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Article DOĞRUSAL OLMAYAN SINIR KOŞULLARINA SAHİP ISI TRANSFERİ PROBLEMLERİNİN SINIR ELEMAN YÖNTEMİ İLE ANALİZİNE YÖNELİK YENİ BİR FORMÜLASYON(2019) Baranoğlu, BesimBu çalışmada Fourier denklemi ile ifade edilen ısı transferi problemlerinin bir ya da daha fazla bölgesinde tanımlı doğrusal olmayan sınır koşulları altında çözümüne yönelik sınır eleman yöntemi tabanlı etkili bir sayısal çözüm sunulmaktadır. Çözüm, sınır eleman yöntemi sistem matrislerinin üzerinde yapılan matematiksel işlemler ile bilinmeyenleri sadece doğrusal olmayan sınır bölgesindeki sıcaklık farkı olan indirgenmiş matris denklemleri elde etmektedir. Bu sayede doğrusal olmayan sınır koşullarına dayalı iterasyonlar daha hızlı gerçekleştirilebilmektedir. Doğrusal olmayan sınır koşullarının tanımlı olduğu bölgelerde çözüm elde edildikten sonra tüm sınır çözümü tanımlı bir son-işlem ile gerçekleştirilebilmektedir. Gerçek çözümü elde edilmiş bir örnek kullanılarak elde edilen sonuçlar değerlendirilmiştir.Article Citation - WoS: 5Citation - Scopus: 5Covid-19 Infection in Peritoneal Dialysis Patients: \ra Comparative Outcome Study With Patients on \rhemodialysis and Patients Without Kidney Disease(Aves, 2022) Kazancıoğlu, Rümeyza; Ozturk, Savas; Turgutalp, Kenan; Gürsu, Meltem; Arıcı, Mustafa; Oruç, Ayşegül; Ateş, KenanObjectives: There is limited data about coronavirus disease-19 (COVID-19) characteristics and results in peritoneal dialysis \r(PD) patients. This study aimed to investigate the characteristics and outcomes among PD patients and compare them with \rmatched hemodialysis (HD) patients and a control group without kidney disease.\rMethods: We included 18 PD patients and consecutive age- and gender-matched 18 HD and 18 patients without kidney \rdisease (control group) registered into the Turkish Society of Nephrology database including 1301 COVID-19 patients. We \rcompared demographic, clinical, radiological, laboratory data, and outcomes namely intensive care unit (ICU) admission, \rmechanical ventilation, mortality, and composite outcome (death and/or ICU admission).\rResults: ICU admission, mechanical ventilation, and mortality rates in PD patients (27.8%, 22.2%, and 22.2%, respectively) \rand the HD group (16.7%, 11.1%, and 16.7%, respectively) were higher than the control group (11.1%, 11.1%, and 5.6%, \rrespectively), but intergroup comparison did not reveal difference. A total of 11 (20.3%) patients had composite outcome \r(6 PD patients, 3 HD patients, and 2 patients in the control group). In Cox regression analysis, higher age and higher CRP level were related to increased risk of composite outcome. Adjusted rate of composite outcome in PD group was significantly higher than \rthe control group (P = .050). This rate was similar in HD and control groups (P = .30).\rConclusions: Combined in-hospital mortality and/or ICU admission of PD patients with COVID-19 was significantly higher than the control \rpatients. There is a need for careful surveillance of PD patients for infection signs and prompt treatment of COVID-19.Article Citation - WoS: 8Citation - Scopus: 10Nöromüsküler Hastalarda Gövde Kontrolünün Değerlendirilmesi: Gövde Bozukluk Ölçeği’nin Geçerlik ve Güvenirliği(Turkish Neurological Soc, 2018) Demir, Yasemin Parlak; Yıldırım, Sibel AksuAmaç: Çalışmamızın amacı Gövde Bozukluk Ölçeği’nin (GBÖ) erişkin nöromüsküler hastalıklarda geçerlik ve güvenirliğini araştırmaktır. Gereç ve Yöntem: Çalışmaya 66 nöromüsküler hastalık tanısı olan birey alındı. Çalışmaya dahil edilen olgulara GBÖ, Manuel Kas Testi (gövde, üst ve alt ekstremite), Motor Fonksiyon Değerlendirme Ölçeği (MFM), Fonksiyonel Bağımsızlık Ölçeği (FIM), Rivermead Mobilite İndeksi (RMI) yapıldı. Bulgular: GBÖ’nün test tekrar test, ICC güvenirlikleri mükemmel bulundu (GBÖ: 0,96 ve 0,98). Cronbach alfa katsayısı 0,82 bulundu. Yapı geçerliği için GBÖ ile MFM (r=0,29), MFM gövde (r=0,31), toplam gövde kas kuvveti (r=0,34), toplam alt ekstremite kas kuvveti (r=0,34, p<0,05), toplam kas kuvveti (gövde, alt ve üst ekstremite) (r=0,52, p<0,05) arasında anlamlı ilişki bulundu. GBÖ uyum geçerliği için FIM (r=0,32, p<0,05) ve RMI (r=0,39, p<0,05) ile ilişkili bulundu. Sonuç: Çalışmanın sonucunda GBÖ’nün erişkin kas hastalıklarında yapı ve uyum geçerliliğinin olduğu ve mükemmel güvenirliğe sahip olduğu bulundu. GBÖ rehabilitasyon kliniklerinde uygulaması kolay ve kısa zaman alan bir ölçektirArticle Citation - WoS: 8Effect of H2o Ratio on Photocatalytic Activity of Sol-Gel Tio2 Powder(Ice Publishing, 2013) Agartan, Lutfi; Kapusuz, Derya; Park, Jongee; Ozturk, AbdullahEffect of water/tetraethyl orthotitanate molar ratio (R) on the formation and morphology of sol-gel-derived titania powder has been studied. Solutions for R of 3 and 5 have been prepared. Initial viscosity of the solutions and viscosity of the gels prepared by aging the solutions for some time were measured. Results revealed that lower gel viscosities lead to better crystallization of the aerogel. Aerogels were dried at 80 degrees C for 24 h and then calcined at 300 degrees C for 1 h to obtain titania powders. The structural and morphological analyses of the powders were performed using X-ray diffraction and scanning electron microscopic characterization techniques. Titania particles obtained after calcination composed of only anatase phase and were in the size range of 9-50 nm. The photocatalytic activity of the powders was evaluated in terms of the degradation of methylene blue (MB) solution under UV (ultraviolet) illumination. A diffuse reflectance spectroscopy was used for the band gap energy measurements. Results revealed that R had a profound effect on the particle morphology and photocatalytic activity of sol-gel-derived titania powders. The titania powders prepared from the solution for R of 5 degraded 99.47% of MB solution under UV illumination in 90 min.Article Citation - WoS: 3On Ciric Type φ-Geraghty Contractions(Chiang Mai Univ, Fac Science, 2019) Alqahtani, Badr; Fulga, Andreea; Karapinar, ErdalIn this paper we introduce the notions of phi-Geraghty contractions and Ciric type phi-Geraghty contractions. We also investigate under which conditions such mappings posses a unique fixed point in the framework of complete metric spaces. We consider examples to show the validity of our main results.Article Citation - WoS: 5Heterogeneity in Classes: Cooperative Problem-Solving Activities Through Cooperative Learning(Fac Teacher Education, 2014) Cigdemoglu, Ceyhan; Kapusuz, Kamil Yavuz; Kara, AliTeachers, from primary schools to college, experience challenges regarding both increased class sizes and a greater diversity of students having a broad spectrum of abilities, interests, needs, and goals. The aim of this paper is to investigate the effect of cooperative learning through Cooperative Problem-Solving (CPS) activities on homogenous and heterogeneous grouping in an engineering course. As a mixed method design, the study utilized both quantitative and qualitative data. The participants, 47 engineering students selected conveniently, were enrolled in a communication systems course. The analysis of the quantitative data indicated that no significant difference (p=.791) exists between the ways in which the students in homogenous and the students in heterogeneous group understand communication systems. In order to reveal the perceptions of students regarding the implementation, they were interviewed at the end of the semester. The qualitative data obtained from these interviews suggests that students prefer heterogeneous to homogenous grouping. The findings also imply that further research should concentrate on heterogeneous grouping strategies and more detailed qualitative data in order to reveal what kind of patterns emerge from students' interactions in different groupings.Article Citation - WoS: 3Citation - Scopus: 4Semptomatik Çok Ciddi Aort Darlıklı Hastalarda Transkateter Aort Kapak İmplantasyonun Etkisi(Kare Publ, 2021) Karaduman, Bilge Duran; Ayhan, Hüseyin; Keles, Telat; Bozkurt, EnginAmaç: Aort darlığı (AD) ilerleyici bir hastalıktır ve tek tedavi seçeneği olan kapak replasmanı semptomatik hale geldikten sonra ve geri dönüşümsüz miyokardiyal hasar gelişmeden önce yapılmalıdır. Çok ciddi aort darlığı (ÇCAD) hastalarında cerrahi kapak replasmanı asemptomatik olsa bile önerilmektedir. Ancak ÇCAD hastalarında transkateter aortik kapak implantasyonunun (TAVI) etkisi hakkında ayrıntılı bir çalışma yoktur. Bu çalışmada amacımız, semptomatik ÇCAD hastalarında TAVI’nin uygulanabilirliğini ve güvenilirliğini göstermektir. Yöntemler: Merkezimizde TAVI uygulanan toplam 505 ardışık semptomatik AD hastası retrospektif olarak incelendi. Hastaların ortalama yaşı 77.8±7.6 yıl ve %56.4 kadın idi. Hastalar ÇCAD grubu (n: 134 hasta) ve yüksek gradyentli AD grubu (YGAD, n: 371 hasta) olarak iki gruba ayrıldı. Bulgular: ÇCAD grubunda daha fazla kadın cinsiyet, daha yüksek sol ventrikül ejeksiyon (SV) fraksiyonu, daha fazla küçük SV, hipertrofik SV, daha fazla normal koronerler ve daha az koroner arter hastalığı, bypas cerrahisi, miyokard enfarktüsü ve atriyal fibrilasyon öyküsü vardı. Predilatasyon ve Edwards SAPIEN 3 ÇCAD grubunda olarak daha az kullanıldı. VARC-2 kriterlerine göre majör komplikasyonlar ve hastane içi mortalitede (ÇCAD grubu; 5 hasta, YG AD grubu; 16 hasta, p: 0.769) istatistiksel fark saptanmadı. İki grup arasında Cox regresyon modeli sağ kalım eğrisinde ÇCAD lehine istatistiksel olarak anlamlı fark vardı (p<0.001). Sonuç: Bu çalışmamız ile semptomatik çok ciddi aort darlığında TAVI’nin kabul edilebilir komplikasyon ve daha yüksek sağ kalım oranları ile uygulanabilir ve güvenli olduğu gösterilmiştir. Hâlihazırda cerrahi kapak replasmanı endikasyonu olan asemptomatik ÇCAD hastalarında TAVI uygulanabilmesi için daha fazla randomize büyük çalışma gereklidir.Article Citation - WoS: 3Citation - Scopus: 4Public Policies and Social Movements: The Implications of Protest Movements on Mining Policy in Turkey(Ankara Haci Bayram veli Univ, 2010) Ozen, Hayriye; Ozen, Suekrue; Department of Public Administration and Political ScienceThis article proposes that public policy and social movements literatures can help each one another achieve for a better understanding of the role of social movements in the process of public policy formation. In order to illustrate this suggestion, taking insights from both types of literatures, we investigate how and to what extent the anti-gold-mining protest movements in Izmir-Bergama, Usak-Esme, Izmir-Efemcukuru, and Canakkale-Balikesir have influenced the mining policy in Turkey since 1985. The results indicate that a centralized policy-making tradition can influence atin what stage of the policy-making process protest movements emerge, and what kindssorts of tactics are pursued. The results also show that the repressive attitude against the protest movements adopted by an advocacy coalition formed between the governments and multinational companies to further enforce the existing policy, can lead to the growth of thegrowing opposition against the existing policy through the emergence of new protest movements.Article Citation - WoS: 2Citation - Scopus: 4State-Based Conceptual Design in Mechatronics Via Petri Nets: a Case Study for an Educational Robot(Romanian Soc Control Tech informatics, 2011) Erden, Zuhal; Mechatronics EngineeringUse of state-based models to represent artifact behaviors at conceptual design is a challenging area for design research. Conceptual design of mechatronic systems needs a multi-domain approach in which the "logical behavior" of a mechatronic design artifact is described without any physical realization. This paper presents a case study on state-based representation for the intended behavior of a non-existent robot at early conceptual level. The behavior is defined through a demonstrative scenario and represented as states and state transitions independent of any physical embodiment. Discrete Event System Specification (DEVS) and Petri Net formalism are used for the model. This representational model is first step towards the development of a virtual prototype for the logical behavior of robot design.Article Citation - WoS: 6Synthesis and Biological Study of Novel Indole-3 Derivatives as Src Kinase and Glutathione S-Transferase Inhibitors(Bentham Science Publ Ltd, 2013) Kurt, Z. Kilic; Aydin, D.; Isgor, Y. G.; Isgor, B. S.; Olgen, S.The aim of this study is to design and synthesize novel dual inhibitors of Src protein tyrosine kinase (PTK) and Glutathione S-transferases (GSTs), as a potential drug lead with therapeutic efficacy on cancer and immune disorders. The biological activity profiling of small molecule inhibitors via miniaturized biochemical techniques compatible with medium throughput screening and focused screening methodologies were performed. To determining the effects of small molecule inhibitors on Src kinase and Phase II detoxification enzyme GST isozymes in liver homogenates used to verify their roles in drug resistance mechanism for cancer chemotherapeutics. In this study, 14 indole-3-imine-2-on and N-benzyl indole-3-imine-2-on derivatives were synthesized for dual activities against Src and GST. The chemical structures and purities of compounds were verified by IR, H-1 NMR, MASS spectroscopy, and elemental analysis. The compounds 2, 3 and 9 are found slightly active against both enzyme Src and GST.
