WoS

Permanent URI for this collectionhttps://hdl.handle.net/20.500.14411/18

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Mild Solutions for Neutral Conformable Fractional Order Functional Evolution Equations Using Meir-Keeler Type Fixed Point Theorem
(University Politehnica Bucharest, Sci Bull, 2025) Berrighi, Fatma; Medjadj, Imene; Karapinar, Erdal
Our mission is to demonstrate the existence, uniqueness, attractiveness, and controllability of mild solutions to neutral conformable fractional-order functional evolution equations, specifically of order between 1 and 2. These intriguing equations encompass finite delay, all while adhering to local conditions within a separable Banach space. By invoking Meir-Keeler's fixed-point Theorem and enhancing it with measures of noncompactness, we establish the existence of these solutions. To highlight the potency of our approach, we present a captivating example.
The Relationship Between Burnout, Caring Behaviors, and Emotional Intelligence in Oncology Nurses
(Elsevier, 2025) Pars, H.; Sari, T.; Caliskan, B. B.; Guner, P.
Dual Zn/Zr Hybrid Framework-Integrated Membranes With Enhanced Proton Conductivity and Durability for High-Temperature PEM Fuel Cells
(Wiley, 2025) Altinisik, Hasan; Devrim, Yilser
This study proposes an innovative strategy for fabricating advanced composite membranes based on a poly[2,2 '-(m-phenylene)-5,5 '-bibenzimidazole] (PBI) matrix for high-temperature proton exchange membrane fuel cells (HT-PEMFCs). A co-synthesized hybrid porous framework incorporating both Zn- and Zr-based nanostructures was integrated into the PBI backbone, ensuring uniform dispersion and strong interfacial bonding, as verified by comprehensive structural and morphological characterizations. This dual-framework architecture promoted the formation of continuous proton-conductive channels and enhanced membrane stability under demanding operating conditions. Furthermore, the membranes were utilized after acid doping, and the hybrid structure effectively mitigated the acid leaching issue, ensuring stable long-term proton conductivity. At 0.6 V and 170 degrees C, the membranes achieved a current density of approximate to 630 mA/cm2, demonstrating the critical role of structural optimization in improving fuel cell efficiency. These findings offer valuable insights into designing scalable, durable, and thermally stable membranes for next-generation HT-PEMFC applications.
The Great Kapok Tree Growing With Turkish Children: A Kincentric "Writing Project
(Springer, 2025) Hasturkoglu, Gokcen
Environmental problems, increasingly felt on a global scale, have necessitated environmental education from a very young age, a vital component of sustainable development efforts. As an integral part of this education, environmental children's literature, especially picturebooks, can give young children the necessary knowledge, cultivate environmental awareness, help develop sustainable behavioral patterns, and increase environmental literacy. In a similar vein, translated picturebooks can create comparable impacts through intentional translational strategies adopted by all translation agents involved in the process. Approaching translation as a writing project, this study aims to explore how the Turkish translation of the environmental picturebook, The Great Kapok Tree, can help foster a kincentric worldview through adding and omitting semiotic modes in the target text and analyze how these changes may transform and potentially enhance or diminish environmental messages in the translated version. The findings reveal the efficacy of the translator's and other translation agents' active involvement in the translation process by framing the translation as a writing project that can reshape the source text to achieve environmental and educational goals.
How TikTok Works for Digital Diplomacy During Conflict/War Times: The Cases of Russia-Ukraine and Israel-Gaza Conflicts
(Routledge Journals, Taylor & Francis Ltd, 2025) Artan Ozoran, Beris; Seyidov, Ilgar; Erdogan, Burak
During times of conflict and war, public diplomacy undergoes a significant transformation, with strategic communication shifting from traditional channels to highly visual and participatory digital platforms. Among these, TikTok has emerged as a key arena for states to shape perceptions and mobilize international audiences. This study explores how TikTok is utilized as a tool of digital diplomacy by examining the official accounts of Ukraine and Israel during the Russia - Ukraine war and the Israel - Gaza conflict. Drawing on Strategic Narrative Theory (SNT), the analysis categorizes state-produced content into system, identity, and issue narratives and investigates how these narrative types effect audience engagement on the platform. By integrating narrative analysis with quantitative engagement metrics, this research not only extends SNT into the context of short-form video platforms but also contributes to the growing literature on digital diplomacy in wartime contexts.
Immigrants and Road Traffic Safety: A Comparison of Cities
(Oxford Univ Press, 2025) Findik, G.
Reconfiguring Stoicism: Convergence of Self-Improvement and Masculinity on TikTok
(Taylor & Francis Ltd, 2025) Agaoglu, Erhan
This research examines the multimodal representations of Stoic content within TikTok. The research aimed to explore the multifaceted structure of an emerging digital philosophy discourse and its implications for contemporary socio-cultural dynamics. It explores a fragmented version of Stoicism, focussing on the affordances of algorithm-driven platforms and modularity principles. For multimodal discourse analysis, 20 highly viewed (>300,000) videos under the hashtags of #stoic and #stoicism are selected through purposeful sampling. It identifies the emergence of a fragmented Stoicism, built upon platform affordances and audio-visual modularity. Emerging themes include self-improvement, being dangerous and traditional masculinity remarking a divergence from popular and classical interpretations of Stoicism. Through these key themes, construction of an arbitrary link between hegemonic masculinity, glorified individualism and Stoicism is explored. Employing elements of aggression, self-isolation and self-improvement, TikTok content creates a novel discourse of Stoicism which is elusive, abstract, and reliant on visually driven narratives.
Persuasive Appeals, Thematic Content, and Affordances on TikTok: Evidence From the 2023 Turkey Presidential Elections
(Routledge Journals, Taylor & Francis Ltd, 2025) Artan Ozoran, Beris; Seyidov, Ilgar; Agaoglu, Erhan
TikTok has become a central arena for political communication, especially in engaging younger voters. This study examines how Recep Tayyip Erdo & gbreve;an and Kemal K & imath;l & imath;& ccedil;daro & gbreve;lu employed TikTok during the 2023 Turkish Presidential Election by analysing 265 videos through quantitative content analysis. Rather than directly measuring voter attitudes, we focus on how leaders' use of affordances (association, editability), thematic content, and rhetorical appeals related to audience engagement (likes, comments, shares). Results show that both leaders prominently highlighted the economy and relied on pathos-driven appeals, consistent with personalization in Turkish political campaigning. Regression analyses revealed that K & imath;l & imath;& ccedil;daro & gbreve;lu's 'other' and 'law/justice' themes significantly boosted engagement, while high use of association features (hashtags and mentions) reduced it. In Erdo & gbreve;an's case, ethos and pathos appeals strongly decreased engagement, whereas logos-based messages performed relatively better. For both leaders, longer videos predicted lower engagement. These findings illustrate how affordances and persuasive strategies interact to shape engagement on TikTok.
The Educational Use of Facebook: A Phenomenological Exploration of Faculty Members' and Students' Lived Experiences
(Frontiers Media Sa, 2025) Kadirhan, Zafer; Yildirim, Soner
Social media has become a pervasive element of higher education; however, the experiences of faculty and students with its educational use remain underexplored. This study employed a transcendental phenomenological design to investigate the lived experiences of three faculty members and 12 students who used Facebook as a learning tool. Data were collected through in-depth, semi-structured interviews and analyzed using Moustakas' transcendental phenomenological method, which allowed for the identification of the essence of participants' experiences while minimizing researcher bias. Findings indicate that Facebook facilitates communication, supports collaborative learning, and provides flexible access to educational resources, enhancing academic engagement. Participants reported benefits, including immediate information sharing and interactive peer support. However, challenges were also noted, including privacy concerns, potential distractions, and the informal nature of interactions, which may affect structured learning. These findings suggest that while Facebook can supplement formal education meaningfully, it should not replace traditional instruction. The study offers practical guidance on balancing engagement, privacy, and curriculum integration, providing educators with insight into thoughtfully leveraging social media in higher education. By presenting both benefits and limitations, this research contributes to a nuanced understanding of Facebook's educational role and informs strategies for its practical use.
Living Between Belief and Consumption: Religiosity, Hedonism, and Life Satisfaction Among Turkish Youth
(Routledge Journals, Taylor & Francis Ltd, 2025) Gungordu Belbag, Aybegum; Erbil, Cihat
This study examines the relationships among religiosity, materialistic hedonism, control, discomfort, and life satisfaction among 256 young individuals in Turkey. Structural equation modeling shows that religiosity does not curb materialistic hedonism and positively affects control. Life satisfaction is positively influenced by control and materialistic hedonism, and negatively by discomfort. Turkish youth form hybrid identities and practices that integrate both faith and consumer desires. A few studies examine contexts like Turkey, where secularism and religiosity coexist, and religious beliefs fulfill broader social and economic functions. The co-existence of religious beliefs and consumerism -especially among middle and lower class youth- remains underexplored.
Impact of Water Consumption on Structural Members in RC Frames Using Multi-Objective Metaheuristics Algorithm
(Taylor & Francis Ltd, 2025) Nader Negarestani, Mohammad; Fatehi-Nobarian, Bahador; Alizadeh Tabrizi, Sina
The construction industry has a significant global water footprint because buildings incorporate large quantities of embedded materials, such as concrete and steel, whose production consumes substantial amounts of water throughout their life cycle. The grey wolf optimizer (GWO) is particularly suitable for this problem because it is a population-based metaheuristic with strong exploration and exploitation balance, which makes it effective in navigating large discrete search spaces such as structural design variables. GWO has demonstrated robustness in multi-objective problems by efficiently approximating Pareto fronts and avoiding local optima. A numerical structural analysis and design model was developed via an application programming interface. This study is indeed the first optimization of the weight of reinforced concrete (RC) structural elements considering virtual water, with the given structural specifications and using the proposed multi-objective metaheuristic methodology. Results showed the optimal structural weight to be 266 tons, with virtual water usage reaching approximately 253 m3. These findings provide actionable insights for sustainable structural design, guiding material selection and early-stage decision-making to minimize virtual water consumption in RC buildings. This study addresses the research gap by introducing virtual water, alongside structural weight, as a novel objective function within multi-objective metaheuristic optimization of RC frames.
The Relationship Between Operational Efficiency and Financial Efficiency in the Shipping Industry: An Example From Privatized Ports in Türkiye
(EDP Sciences S A, 2025) Kaya, Ebru Nur; Mete, Mevlut Hurol; Belgin, Onder
Since the ports are the backbone of international trade they need to be managed efficiently. This study addresses to analyze the operational and financial efficiency of the selected privatized ports that have been belonged to TCDD (Republic of T & uuml;rkiye State Railways). For this purpose, EATWOS (Efficiency Analysis Technique with Output Satisfying) method is employed, and the weights of the inputs and outputs are determined using LOPCOW (Logarithmic Percentage Change-Driven Objective Weighting), MEREC (Method Based on the Removal Effects of Criteria), and CRITIC (Criteria Importance Through Intercriteria Correlation) methods. After obtaining the weights from these objective methods, the comprehensive weights are calculated using TPOP (Technique of Precise Order Preference) method. Finally, Spearman's rank-order correlation shows that there is no relationship between the operational and financial efficiency of the ports. The number of studies that address both operational and financial efficiency of ports is limited, and this study distinguishes itself by investigating the relationship between both efficiency types.
Design and Fabrication of Dual-Layered PCL/PEG Theranostic Platforms Using 3D Melt Electrowriting for Targeted Delivery and Post-Treatment Monitoring
(Springer, 2025) Ege, Zeynep Ruya; Enguven, Gozde; Ege, Hasan; Durukan, Barkan Kagan; Sasmazel, Hilal Turkoglu; Gunduz, Oguzhan
Advanced pancreatic tumors remain highly resistant to treatment due to their dense stromal environment and poor vascularization, which limit drug penetration and efficacy. Even after surgical resection, the high recurrence rate frequently leads to poor prognosis and mortality. To address these challenges, we developed solvent-free three-dimensional (3D) melt electrowritten (MEW) theranostic microfiber patches composed of poly(epsilon-caprolactone) (PCL) and polyethylene glycol (PEG). The patches were designed as dual-layered, 10-layer structures, with gemcitabine (GEM) loaded in the bottom five layers for localized chemotherapy to suppress tumor recurrence, and indocyanine green (ICG) incorporated in the top five layers to enable fluorescence-based post-surgical monitoring. Following fabrication, the patches were characterized both materially and in vitro, with GEM loaded at 100, 250, or 500 mu g/ml. PEG incorporation improved patch flexibility, facilitating the implantation process. In vitro release analysis demonstrated an initial burst followed by sustained, pH-responsive GEM release (similar to 70% at pH 4.0 and similar to 30% at pH 7.4 for 500 mu g/mL GEM at 168 h), while ICG release reached similar to 25% (pH 7.4) and similar to 10% (pH 4.0). GEM-loaded patches significantly reduced Capan-1 cell viability in a dose- and time-dependent manner, achieving >= 50% reduction at 72 h with 500 mu g/mL. Importantly, ICG incorporation did not impair GEM cytotoxicity; confocal imaging confirmed ICG internalization in viable cells and showed a decline in ICG-positive cells with increasing GEM dose, supporting the potential for concurrent therapy and monitoring. Thus, the theranostic patches enable localized, pH-responsive GEM delivery with integrated ICG-based fluorescence imaging, achieving significant cytotoxicity against pancreatic cancer cells while providing a platform for post-surgical surveillance. This solvent-free, layer-addressable approach represents a promising strategy for personalized, locally implantable theranostic systems in pancreatic cancer treatment.
Bibliometric Analysis of Authors Contributing to the Development of Health Management and Studies Published in WOS in the Field of Health Management
(Sage Publications India Pvt Ltd, 2025) Tengilimoglu, Dilaver; Tas, Merve Ozzeybek; Seyhan, Firat; Younis, Mustafa Z.
In this study, scientific publications on the management of health institutions and health services, which are becoming increasingly important both in the country and in the world agenda, have been analysed, and it is aimed to make a comprehensive determination by analysing the annual publication amounts, most cited works, most relevant and influential source analysis, source co-citation network analysis, most relevant and influential author analysis, cooperation between authors analysis, author co-citation network analysis, and country's scientific production map and cooperation analysis. The result of the analysis showed that 3,940 article-type documents were published from 1,466 different sources between 1977 and 2021. The country that published the highest number of articles in the field of study was the USA, with 3,405 articles. In the analysis of the most relevant and influential sources, the most relevant source was found as 'Health Policy', which has published 80 articles since its first publication in 1986. The most relevant author in the study field was Yasumura who published 63 articles in total and was found to be one of the most influential authors in the study field. This study is evaluated to provide a macroscopic perspective for all stakeholders interested in the subject and those involved in the health system by providing a holistic perspective.
Clinicopathological Predictors of Central Lymph Node Metastasis in Clinically Node-Negative Papillary Thyroid Carcinoma: A Retrospective Cohort Analysis
(Springer, 2025) Sakiz, Davut; Calapkulu, Murat; Sencar, Muhammed Erkam; Unsal, Ilknur Ozturk; Kartal, Mehmet Zabit; Ucan, Bekir; Cakal, Erman
PurposeThis retrospective cohort study aimed to identify clinicopathological predictors of central lymph node metastasis (CLNM) in patients with papillary thyroid carcinoma (PTC).MethodsA total of 503 patients with PTC who underwent thyroidectomy with central lymph node dissection were included. Preoperative clinical data, ultrasonographic features, and postoperative histopathological characteristics were analyzed.ResultsCLNM was detected in 209 (41.55%) patients. Male sex (odds ratio [OR] = 3.12, 95% CI: 1.82-5.35), irregular nodule borders (OR = 2.02, 95% CI: 1.25-3.26) and higher risk categories in the American Thyroid Association (ATA) ultrasonographic pattern stratification system (OR = 13.312, 95% CI: 8.623-20.551) were identified as independent preoperative predictors of CLNM. A simplified model incorporating only the ATA ultrasonographic pattern stratification system and male sex achieved 83.5% accuracy in predicting CLNM. Histopathological evaluation revealed lymphovascular invasion (OR = 4.61, 95% CI: 2.81-7.55), extrathyroidal extension (OR = 2.41, 95% CI: 1.52-3.83), and multifocality (OR = 1.58, 95% CI: 1.04-2.40) as independent predictors of CLNM, while lymphocytic thyroiditis (OR = 0.59, 95% CI: 0.39-0.89) was a protective factor.ConclusionThis study establishes that ATA ultrasonographic suspicion patterns combined with the male sex provide an accurate and simplified model for preoperative CLNM prediction in PTC, outperforming complex nomograms. Key independent predictors included male sex, irregular nodule margins, ATA high-risk patterns, lymphovascular invasion, extrathyroidal extension, and multifocality, while lymphocytic thyroiditis was protective. According to the current study, risk assessment and personalized management should favor a holistic approach, rather than focusing solely on individual risk factors.
From Street Canyons To Corridors: Adapting Urban Propagation Models for an Indoor IQRF Network
(MDPI, 2025) Doyan, Talip Eren; Yalcinkaya, Bengisu; Dogan, Deren; Dalveren, Yaser; Derawi, Mohammad
Among wireless communication technologies underlying Internet of Things (IoT)-based smart buildings, IQRF (Intelligent Connectivity Using Radio Frequency) technology is a promising candidate due to its low power consumption, cost-effectiveness, and wide coverage. However, effectively modeling the propagation characteristics of IQRF in complex indoor environments for simple and accurate network deployment remains challenging, as architectural elements like walls and corners cause substantial signal attenuation and unpredictable propagation behavior. This study investigates the applicability of a site-specific modeling approach, originally developed for urban street canyons, to characterize peer-to-peer (P2P) IQRF links operating at 868 MHz in typical indoor scenarios, including line-of-sight (LoS), one-turn, and two-turn non-line-of-sight (NLoS) configurations. The received signal powers are compared with well-known empirical models, including international telecommunication union radio communication sector (ITU-R) P.1238-9 and WINNER II, and ray-tracing simulations. The results show that while ITU-R P.1238-9 achieves lower prediction error under LoS conditions with a root mean square error (RMSE) of 5.694 dB, the site-specific approach achieves substantially higher accuracy in NLoS scenarios, maintaining RMSE values below 3.9 dB for one- and two-turn links. Furthermore, ray-tracing simulations exhibited notably larger deviations, with RMSE values ranging from 7.522 dB to 16.267 dB and lower correlation with measurements. These results demonstrate the potential of site-specific modeling to provide practical, computationally efficient, and accurate insights for IQRF network deployment planning in smart building environments.
Evaluation of Space Efficiency, Structural Systems, Material Applications, and Design of High-Rise Structures in South Korea
(Highlights of Science, 2025) Aktas, Kurt Orkun; Zaim, Ajda; Aslantamer, Ozlem Nur; Aktas, Gozen Guner; Ilgin, Huseyin Emre
This study examines 61 South Korean towers, analyzing their architectural configurations, structural systems, material applications, and spatial efficiencies. Findings indicate a predominance of central core configurations and prismatic forms, reinforcing a function-driven approach to vertical urbanism. Structural system preferences highlight the widespread use of outriggered frames, ensuring lateral stability while optimizing floor layouts. Material selection trends reveal a reliance on concrete, aligning with global patterns, while composite materials (25%) are used in high-performance supertall structures. Functionally, residential high-rises dominate, with mixed-use (2%) and office towers (11%) remaining limited. This research also identifies an average spatial efficiency of 76%, aligning with international benchmarks, though variations exist across cities due to core-to-gross floor area ratios, structural constraints, and service core allocations. This research underscores South Korea's strategic high-rise development, prioritizing space optimization, structural efficiency, and economic feasibility. However, opportunities remain for increased functional diversity, broader hybrid material adoption, and greater integration of sustainable design innovations. These findings contribute to global skyscraper analysis, offering insights into high-rise architecture's role in urban resilience and density management.
Effectiveness of Boric Acid in Sepsis in Rats With Cecal Perforation
(Springer Nature, 2025) Kurtipek, Ali Can; Dursun, Ali Dogan; Yigman, Zeynep; Ozdemir, Cagri; Kucuk, Aysegul; Gonullu, Ugur; Arslan, Mustafa
Introduction and AimSepsis is a systemic inflammatory response that develops in the host against microorganisms, which results in end-organ damage. Boric acid (BA) has been shown to have immune modulatory effects in vitro and in animal studies. The aim of the study is to investigate the effects of high dose BA on lung and kidney tissues in rats with sepsis induced by the CLP method.Method28 rats were randomly divided into four groups: Group C (control group), Group BA, Group CLP (cecal ligation and puncture), and Group CLP + BA. Cecum was ligated below the ileocecal valve and punctured. BA was administered to the treatment groups at an intraperitoneal dose of 200 mg/kg, and at the end of 24 h, lung and kidney tissue samples were collected and evaluated for biochemical and histopathological parameters.ResultsHistopathologically, in kidney tissue, CLP + BA group showed significantly less peritubular capillary dilatation and brush border loss in the proximal tubule epithelium compared to the CLP group. In lung tissue, CLP + BA group had significantly less alveolar wall thickening compared to the CLP group. Biochemical analyses indicated that BA administration reduced oxidative stress in both renal and lung tissues.ConclusionWe found that intraperitoneal administration of high dose boric acid partially ameliorated the tissue damage in rats subjected to CLP induced sepsis. Further studies are needed regarding the dosage and application at different time points.
Evaluation of Anti-Tetanus IgG Antibody Levels and Influencing Factors in Patients Undergoing Hemodialysis
(Frontiers Media Sa, 2025) Ozsoy, Metin; Ozturk, Hakki; Tuna, Aysegul; Varlibas, Artuner; Cesur, Salih; Aksoy, Altan; Demir, Mehmet Emin
Aim: This study aimed to assess anti-tetanus IgG antibody levels and identify determinants of inadequate tetanus immunity among maintenance hemodialysis (HD) patients. Methods: In this cross-sectional study, anti-tetanus IgG levels were measured by quantitative ELISA in 162 adult HD patients from two dialysis centers in Ankara, Turkey. Protective immunity was evaluated using both international (>= 0.1 IU/mL) and robust (>= 0.5 IU/mL) cut-offs. Demographic and clinical factors associated with immunity were analyzed by multivariate logistic regression. Results: Only 16.7% of HD patients achieved robust protection (>= 0.5 IU/mL), whereas 49.8% had minimal protection (>= 0.1 IU/mL). Protective immunity was independently associated with younger age (OR 1.07 per year; p = 0.004), shorter dialysis duration (OR 1.07; p = 0.030), male sex (female OR 2.92; p = 0.048), and recent booster vaccination within 10 years (OR 0.11; p < 0.001). Diabetes mellitus was not an independent factor. Conclusion: Most HD patients lacked durable tetanus immunity, particularly older females on long-term dialysis. The findings highlight the need for regular antibody monitoring, early revaccination, and structured booster programs to maintain adequate protection in this high-risk population.
Genomic Characterization of Five Novel Salmonella Phages and the Assessment of Their Biocontrol Potential for the Preservation of Chicken Meat
(Elsevier, 2026) Cufaoglu, Gizem; Cengiz, Gorkem; Acar, Bahar Onaran; Kardogan, Ozlem; Onmaz, Nurhan Ertas; Unal, Gultekin; Ayaz, Naim Deniz
The rise of multidrug-resistant Salmonella poses a significant threat to food safety and public health, necessitating novel antimicrobial strategies. The primary objective of this study was to characterize novel bacteriophages and assess their biocontrol potential against predominant Salmonella serotypes. A total of 84 lytic bacteriophages specific to various Salmonella enterica serotypes were isolated from wastewater sources across T & uuml;rkiye. Five phages (S.Hadar 4-5-1, S.Inf 5-2, S.Typ Adana, S.Ent 1-35-3, and S.Kent 1-2-1) demonstrating broad lytic activity to tested major serotypes (S. Enteritidis, S. Typhimurium, S. Infantis, S. Kentucky, S. Newport, S. Hadar, S. Gallinarum and S. Pullorum) and genetic diversity were selected for detailed phenotypic and genomic analysis. These phages, four from Siphoviridae and one from Podoviridae, exhibited tolerance to thermal (up to 60 degrees C) and mildly acidic conditions (pH 4), as well as 12-month stability when stored in Tris-Buffered Saline (TBS) with 20 % (v/v) glycerol at -20 degrees C and - 80 degrees C. Whole-genome sequencing confirmed their novelty and the absence of antimicrobial resistance and virulence genes. A cocktail formulated from these phages was applied against Salmonella Enteritidis both in-vitro (at 37 degrees C) and on artificially contaminated chicken wings (at 4 degrees C). The phage cocktail effectively reduced Salmonella counts in both environments, keeping levels below the detection limit (< 1 log CFU/g) over 24 h. For chicken wings food model, bacterial reductions reached 3.30 log CFU/g and 4.86 log CFU/g. These results underscore the potential of the newly characterized Salmonella phages as effective tools for controlling bacterial contamination on chicken meat, supporting their use as a natural, and antibiotic-free strategy in modern food safety management.

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