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Article Citation - WoS: 10Citation - Scopus: 10Higher Rates of Cefiderocol Resistance Among Ndm Producing klebsiella Bloodstream Isolates Applying Eucast Over Clsi Breakpoints(Taylor & Francis Ltd, 2023) Isler, Burcu; Vatansever, Cansel; Ozer, Berna; Cinar, Gule; Aslan, Abdullah Tarik; Falconer, Caitlin; Harris, Patrick N. A.BackgroundCefiderocol is generally active against carbapenem-resistant Klebsiella spp. (CRK) with higher MICs against metallo-beta-lactamase producers. There is a variation in cefiderocol interpretive criteria determined by EUCAST and CLSI. Our objective was to test CRK isolates against cefiderocol and compare cefiderocol susceptibilities using EUCAST and CLSI interpretive criteria.MethodsA unique collection (n = 254) of mainly OXA-48-like- or NDM-producing CRK bloodstream isolates were tested against cefiderocol with disc diffusion (Mast Diagnostics, UK). Beta-lactam resistance genes and multilocus sequence types were identified using bioinformatics analyses on complete bacterial genomes.ResultsMedian cefiderocol inhibition zone diameter was 24 mm (interquartile range [IQR] 24-26 mm) for all isolates and 18 mm (IQR 15-21 mm) for NDM producers. We observed significant variability between cefiderocol susceptibilities using EUCAST and CLSI breakpoints, such that 26% and 2% of all isolates, and 81% and 12% of the NDM producers were resistant to cefiderocol using EUCAST and CLSI interpretive criteria, respectively.ConclusionsCefiderocol resistance rates among NDM producers are high using EUCAST criteria. Breakpoint variability may have significant implications on patient outcomes. Until more clinical outcome data are available, we suggest using EUCAST interpretive criteria for cefiderocol susceptibility testing.Article Citation - WoS: 2Citation - Scopus: 2An Investigation of Recycled Rubber Composites Reinforced With Micro Glass Bubbles: an Experimental and Numerical Approach(Taylor & Francis Ltd, 2024) Kabakci, Gamze Cakir; Bayraktar, Emin; Aslan, OzgurRecycled rubber is widely used for its lightweight and cost-effective properties but often has limited mechanical strength, restricting its applications. This study enhances the mechanical performance of devulcanised recycled rubber by reinforcing it with micro glass bubbles (GBs) featuring a density of 0.65 g/cm(3) and an elastic modulus of 3.5 GPa, offering a high strength-to-density ratio. Uniaxial compression tests were conducted on samples with GB volume fractions of 5%, 10%, and 15%. Results were validated through finite element analysis (FEA) in ABAQUS/Standard, incorporating randomised GB distributions. A 2D representative volume element (RVE) with randomly distributed GBs was modelled, applying periodic boundary conditions to simplify the composite into an equivalent homogeneous material. Numerical simulations assessed the effects of GB diameters (30, 40, and 50 mu m) and inclusion size ranges (20-50 mu m and 10-60 mu m), finding minimal impact on results. The RVE, sized at 238 mu m, accurately represented macroscale composite behaviour. Stress-strain behaviour was analysed using average stress and strain tensors. The strong agreement between experimental and numerical results validates the proposed method, demonstrating its accuracy in predicting the mechanical behaviour of the reinforced composite material.Article Citation - WoS: 11Citation - Scopus: 12Structural, optical, electrical and dielectric properties of Bi1.5Zn0.92Nb1.5-xNixO6.92-3x/2 solid solution(Taylor & Francis Ltd, 2012) Qasrawi, A. F.; Nazzal, E. M.; Mergen, A.The effects of Ni content on the structural, optical, dielectric and electrical properties of Bi1.5Zn0.92Nb1.5O6.92 pyrochlore ceramics have been investigated. Nickel atoms were inserted into pure samples in accordance to the composition Bi1.5Zn0.92Nb1.5-xNixO6.92-3x/2, with x varying from 0.07 to 0.40. The structural analysis revealed that a single phase of the pyrochlore compound can be obtained for x values of 0.07 and 0.10 only. Further increase in Ni caused the appearance of multiple phases. The optical energy band gaps are determined as 3.30, 3.35 and 3.52 eV for Ni content of 0.00, 0.07 and 0.10 respectively. The temperature dependent electrical resistivity and the frequency dependent capacitance are observed to increase with increasing Ni content. The resonance frequency, which was determined from the capacitance-frequency dependence, was observed to shift from 12.14 to 10.47 kHz as the x values increase from 0.00 to 0.10 respectively.Article Citation - WoS: 11Citation - Scopus: 20Simulation of the Flood Wave Caused by Hypothetical Failure of the Haditha Dam(Taylor & Francis Ltd, 2023) Mhmood, Harith Hamad; Yilmaz, Meric; Sulaiman, Sadeq OleiwiIn this research, the flood wave resulting from the hypothetical overtopping failure of the Haditha Dam on the Euphrates River, Iraq, was simulated, utilizing the ArcMap 10.2 and HEC-RAS 5.0.7 software and the observed field data from the Iraqi Ministry of Water Resources. Flooding parameters were calculated, for the study reach from the Haditha Dam to Heet city and major cities in between. The Manning coefficient of the study reach was calibrated to 0.035 and 0.07 for the main river and the floodplain, respectively. The results showed the flood wave propagation along the study reach, the flood hydrograph and time to the peak discharge/time to the maximum water surface elevation, maximum velocity, and width of the inundated area at the selected cities. The analysis outputs and the inundation maps can be used to provide an emergency action plan for the flooded regions.Article Citation - WoS: 1Citation - Scopus: 1Machine Vs. Deep Learning Comparision for Developing an International Sign Language Translator(Taylor & Francis Ltd, 2022) Eryilmaz, Meltem; Balkaya, Ecem; Ucan, Eylul; Turan, Gizem; Oral, Seden GulayThis study aims to enable deaf and hard-of-hearing people to communicate with other individuals who know and do not know sign language. The mobile application was developed for video classification by using MediaPipe Library in the study. While doing this, considering the problems that deaf and hearing loss individuals face in Turkey and abroad modelling and training stages were carried out with the English language option. With the real-time translation feature added to the study individuals were provided with instant communication. In this way, communication problems experienced by hearing-impaired individuals will be greatly reduced. Machine learning and Deep learning concepts were investigated in the study. Model creation and training stages were carried out using VGG16, OpenCV, Pandas, Keras, and Os libraries. Due to the low success rate in the model created using VGG16, the MediaPipe library was used in the formation and training stages of the model. The reason for this is that, thanks to the solutions available in the MediaPipe library, it can normalise the coordinates in 3D by marking the regions to be detected in the human body. Being able to extract the coordinates independently of the background and body type in the videos in the dataset increases the success rate of the model in the formation and training stages. As a result of an experiment, the accuracy rate of the deep learning model is 85% and the application can be easily integrated with different languages. It is concluded that deep learning model is more accure than machine learning one and the communication problem faced by hearing-impaired individuals in many countries can be reduced easily.Article Mixed Method Investigation of the Major Challenges to the Sustainable Deployment of the Electric Vehicle Charging Station Network in Türkiye(Taylor & Francis Ltd, 2025) Erol, Ismail; Oztel, Ahmet; Peker, Iskender; Ar, Ilker Murat; Benli, Tolga; Turan, IsmetCharging the increasing number of electric vehicles (EVs) in use requires the deployment of EV charging station networks (EVCSN). However, there are various challenges to deploying EVCSN in a sustainable manner. T & uuml;rkiye, a developing country, should also build a robust EVCSN to encourage future adoption of EVs as the country's market for EVs has been rapidly growing. The literature review concludes that no previous study has systematically explored challenges to the sustainable deployment of EVCSN. The goal of this study is, therefore, twofold: first, it identifies those challenges through the lenses of commonly used theories. Second, it explores them using a multi-criteria decision-making (MCDM) framework that incorporates a rough-derived interval-valued neutrosophic set (R-IVN)-based ISM into MICMAC. By deriving interval neutrosophic information from single-valued expert inputs using rough number operators, the proposed approach more accurately captures epistemic uncertainty and variability in expert judgments compared to conventional interval-based models. The method is further validated through a novel Dice-S & oslash;rensen similarity index-based simulation approach. The findings of this study suggest that developing government policies and regulations and addressing the existence of vertically integrated companies are the critical challenges with higher driving powers. These findings provide key responsibilities for stakeholders, including urban municipalities, in developing guidelines for EVCSN deployment.Article Citation - WoS: 17Citation - Scopus: 17A New Outlier Detection Method Based on Convex Optimization: Application To Diagnosis of Parkinson's Disease(Taylor & Francis Ltd, 2021) Taylan, Pakize; Yerlikaya-Ozkurt, Fatma; Bilgic Ucak, Burcu; Weber, Gerhard-WilhelmNeuroscience is a combination of different scientific disciplines which investigate the nervous system for understanding of the biological basis. Recently, applications to the diagnosis of neurodegenerative diseases like Parkinson's disease have become very promising by considering different statistical regression models. However, well-known statistical regression models may give misleading results for the diagnosis of the neurodegenerative diseases when experimental data contain outlier observations that lie an abnormal distance from the other observation. The main achievements of this study consist of a novel mathematics-supported approach beside statistical regression models to identify and treat the outlier observations without direct elimination for a great and emerging challenge in humankind, such as neurodegenerative diseases. By this approach, a new method named as CMTMSOM is proposed with the contributions of the powerful convex and continuous optimization techniques referred to as conic quadratic programing. This method, based on the mean-shift outlier regression model, is developed by combining robustness of M-estimation and stability of Tikhonov regularization. We apply our method and other parametric models on Parkinson telemonitoring dataset which is a real-world dataset in Neuroscience. Then, we compare these methods by using well-known method-free performance measures. The results indicate that the CMTMSOM method performs better than current parametric models.Article Citation - WoS: 2Citation - Scopus: 2Influence of Surface Finish on Flexural Strength and Microhardness of Indirect Resin Composites and the Effect of Thermal Cycling(Taylor & Francis Ltd, 2012) Bicer, Arzu Zeynep Yildirim; Dogan, Arife; Dogan, Orhan Murat; Sengonul, Merih Cemal; Artvin, ZaferThis study investigated the effect of surface finish and thermal cycling procedures on flexural strength and surface microhardness of three indirect resin composites, Artglass (R), Signum (R), and Solidex (R). The specimens were prepared in sufficient number and size according to flexural and microhardness test requirements (n=10). Scanning electron microscopy-energy dispersive x-ray (SEM-EDX) analysis was also used for studying the morphology, dispersion, and elemental compositions of fillers. The EDX results showed that Artglass contained 1.57% aluminium oxide (Al2O3), 53.29% silicon dioxide (SiO2), and 2.62% barium oxide (BaO); Signum had 55.69% silicon dioxide (SiO2) and Solidex had 44.99% silicon dioxide (SiO2) of total mass. Artglass appeared to display the best flexural strength values under all the test conditions employed (range: 116.8 +/- 32.18 to 147.8 +/- 47.97 MPa), and it was followed by Signum (range: 93.7 +/- 22.84 to 118.0 +/- 33.45 MPa). Thermal cycling did not seem to have affected the flexural strength of Artglass and Signum (p > 0.05); however, it led to a significant decrease, from (110.5 +/- 20.69 MPa) to 74.0 +/- 13.30 MPa (p < 0.001), in the strength of polished Solidex specimens. While surface microhardness of the three materials increased by polishing ( Artglass: 55.7 +/- 2.64/74.1 +/- 8.63 Vickers Hardness Numbers (VHN); Signum: 44.8 +/- 3.12/60.7 +/- 4.50 VHN; Solidex: 44.0 +/- 2.31/53.4 +/- 3.58 VHN for unpolished/polpolished specimens), thermal cycling had a deleterious effect on this property (p < 0.001).Article Citation - WoS: 1Citation - Scopus: 1On the Eigenfunction Expansion of the Laplace-Beltrami Operator in Hyperbolic Space(Taylor & Francis Ltd, 2015) Guseinov, Gusein Sh.We describe the spectral projection of the Laplace-Beltrami operator in n-dimensional hyperbolic space by studying its resolvent as an analytic operator-valued function and applying the technique of contour integration. As a result an integral formula is established for the associated Legendre functionArticle Citation - WoS: 8Citation - Scopus: 9First-principles studies of Tin+1SiNn (n=1, 2, 3) MAX phase(Taylor & Francis Ltd, 2020) Surucu, Gokhan; Gullu, Hasan Huseyin; Candan, Abdullah; Yildiz, Bugra; Erkisi, AytacIn this study, the structural, electronic, mechanical, lattice dynamical and thermodynamic characteristics of ( 1, 2 and 3) phase compounds were investigated using the first principle calculations. These ternary nitride compounds were found to be stable and synthesisable, and the results on the stability nature of them were also evaluated for the possible and phases. -was found to be the most stable one among these new class of layered phases for which limited works are available in the literature. The band structures, that are essential for the electronic properties, were determined along with the partial density of states (PDOS) indicating the metallic behaviour of these compounds. The polycrystalline elastic moduli were calculated based on the single-crystal elastic constants and the mechanical stabilities were verified. Some basic physical parameters, such as bulk modulus, shear modulus, Young's modulus, Poisson's ratio, Debye temperature, and sound velocities, were also predicted. Furthermore, the anisotropic elastic properties were visualised in three dimensions (3D) for Young's modulus, linear compressibility, shear modulus and Poisson's ratio as well as with the calculation of the anisotropic factors. - phase showed the most isotropic characteristics with minimum deviations. These theoretical values were also used to identify the stiffness and ionic characteristics. The phonon dispersion curves and corresponding PDOS indicated that compounds were dynamically stable. Moreover, thermodynamic properties obtained from phonon dispersion curves were investigated in detail.
