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Article Citation - WoS: 3Citation - Scopus: 4Some Permutations and Complete Permutation Polynomials Over Finite Fields(Tubitak Scientific & Technological Research Council Turkey, 2019) Ongan, Pınar; Temür, Burcu Gülmez; Gülmez Temür, BurcuIn this paper we determine $b\\in F_{q^n}^\\ast$ for which the polynomial $f(x)=x^{s+1}+bx\\in F_{q^n}\\left[x\\right]$ is a permutationpolynomial and determine $b\\in F_{q^n}^\\ast$ for which the polynominal $f(x)=x^{s+1}+bx\\in F_{q^n}\\left[x\\right]$ is a complete permutationpolynomial where $s=\\frac{q^n-1}t,\\;t\\in\\mathbb{Z}^+$ such that $\\left.t\\;\\right|\\;q^n-1$.Article Neuron Modeling: Estimating the Parameters of a Neuron Model From Neural Spiking Data(Tubitak Scientific & Technological Research Council Turkey, 2018) Doruk, Resat Ozgur; Doruk, OzgurWe present a modeling study aiming at the estimation of the parameters of a single neuron model from neural spiking data. The model receives a stimulus as input and provides the firing rate of the neuron as output. The neural spiking data will be obtained from point process simulation. The resultant data will be used in parameter estimation based on the inhomogeneous Poisson maximum likelihood method. The model will be stimulated by various forms of stimuli, which are modeled by a Fourier series (FS), exponential functions, and radial basis functions (RBFs). Tabulated results presenting cases with different sample sizes (# of repeated trials), stimulus component sizes (FS and RBF), amplitudes, and frequency ranges (FS) will be presented to validate the approach and provide a means of comparison. The results showed that regardless of the stimulus type, the most effective parameter on the estimation performance appears to be the sample size. In addition, the lowest variance of the estimates is obtained when a Fourier series stimulus is applied in the estimation.Article Citation - WoS: 1Citation - Scopus: 1A Short Note on Some Arithmetical Properties of the Integer Part of Ap(Tubitak Scientific & Technological Research Council Turkey, 2019) Akbal, YıldırımLet $a>0$ be an irrational number. We study some of the arithmetical properties of ${\\{\\lfloor ap\\rfloor\\}}_{p=2}^\\infty$ where pdenotes a prime number and $\\lfloor x\\rfloor$ denotes the largest integer not exceeding x.Article Citation - WoS: 3Citation - Scopus: 5Investigation of the Effect of Hyperthyroidism on Endoplasmic Reticulum Stress and Transient Receptor Potential Canonical 1 Channel in the Kidney(Tubitak Scientific & Technological Research Council Turkey, 2021) Aykanat, Nuriye Ezgi Bektur; Şahin, Erhan; Kaçar, Sedat; Bağcı, Rıdvan; Karakaya, Şerife; Dönmez, Dilek Burukoğlu; Şahintürk, Varol; Bektur Aykanat, Nuriye Ezgi; Burukoğlu Dönmez, Dilek; Bektur, EzgiBackground/aim: Hyperthyroidism is associated with results in increased glomerular filtration rate as well as increased renin-angiotensin-aldosterone activation. The disturbance of Ca2+ homeostasis in the endoplasmic reticulum (ER) is associated with many diseases, including diabetic nephropathy and hyperthyroidism. Transient receptor potential canonical 1 (TRPC1) channel is the first cloned TRPC family protein. Although it is expressed in many places in the kidney, its function is uncertain. TRPC1 is involved in regulating Ca2+ homeostasis, and its upregulation increases ER Ca2+ level, activates the unfolded protein response, which leads to cellular damage in the kidney. This study investigated the role of TRPC1 in the kidneys of hyperthyroid rats in terms of ER stress markers that are glucose-regulated protein 78 (GRP78), activating transcription factor 6 (ATF6), (protein kinase R (PKR)-like endoplasmic reticulum kinase) (PERK), Inositol-requiring enzyme 1 (IRE1). Materials and methods: Twenty male rats were assigned into control and hyperthyroid groups (n = 10). Hyperthyroidism was induced by adding 12 mg/L thyroxine into the drinking water of rats for 4 weeks. The serum-free T3 and T4 (fT3, fT4), TSH, blood urea nitrogen (BUN), and creatinine levels were measured. The histochemical analysis of kidney sections for morphological changes and also immunohistochemical and western blot analysis of kidney sections were performed for GRP78, ATF6, PERK, IRE1, TRPC1 antibodies. Results: TSH, BUN, and creatinine levels decreased while fT3 and fT4 levels increased in the hyperthyroid rat. The morphologic analysis resulted in the capillary basal membrane thickening in glomeruli and also western blot, and immunohistochemical results showed an increase in TRPC1, GRP78, and ATF6 in the hyperthyroid rat (p < 0.05). Conclusion: In conclusion, in our study, we showed for the first time that the relationship between ER stress and TRPC1, and their increased expression caused renal damage in hyperthyroid rats.Key words: Hyperthyroidism, endoplasmic reticulum (ER) stress, transient receptor potential canonical 1 (TRPC1), kidney, ratArticle Fedja’s Proof of Deepti’s Inequality(Tubitak Scientific & Technological Research Council Turkey, 2018) Ostrovska, Sofiya; Turan, MehmetThe paper aims to present, in a systematic way, an elegant proof of Deepti’s inequality. Both the inequalityand various ideas concerning the issue were discussed on the Mathoverflow website by a number of users, but none haveappeared in the literature thus far. In this work, suggestions pertaining to users ‘Deepti’ and ‘fedja’ are traced, whencethe title. The results or the paper are new, and the proof is divided into a series of statements, many of which are ofinterest in themselves.Article A Wavelet-Based Feature Set for Recognizing Pulse Repetition Interval Modulation Patterns(2016) Gençol, Kenan; At, Nuray; Kara, AlıThis paper presents a new feature set for the problem of recognizing pulse repetition interval (PRI) modulation patterns. The recognition is based upon the features extracted from the multiresolution decomposition of different types of PRI modulated sequences. Special emphasis is placed on the recognition of jittered and stagger type PRI sequences due to the fact that these types of PRI sequences appear predominantly in modern electronic warfare environments for some specific mission requirements and recognition of them is heavily based on histogram features. We test our method with a broad range of PRI modulation parameters. Simulation results show that the proposed feature set is highly robust and separates jittered, stagger, and other modulation patterns very well. Especially for the stagger type of PRI sequences, wavelet-based features outperform conventional histogram-based features. Advantages of the proposed feature set along with its robustness criteria are analyzed in detail.Article ISAR Imaging of Drone Swarms at 77 GHz(Tubitak Scientific & Technological Research Council Turkey, 2025) Coruk, Remziye Busra; Kara, Ali; Aydin, ElifThe proliferation of easily available, internet-purchased drones, coupled with the emergence of coordinated drone swarms, poses a significant security threat for airspace. Detecting these swarms is crucial to prevent potential accidents, criminal misuse, and airspace disruptions. This paper proposes a novel inverse synthetic aperture radar (ISAR) imaging technique for high-resolution reconstruction of drone swarms at 77 GHz millimeter wave (mmWave) frequency, offering a valuable tool for military and defense antidrone systems. The key parameters affecting down-range and cross-range resolution (0.05 m), ultimately enabling the generation of detailed ISAR images are discussed. Here, we create diverse scenarios encompassing various swarm formations, sizes, and payload configurations by employing ANSYS simulations. To enhance image quality, different window functions are evaluated, and the Hamming window is selected due to its highest peak signal-to-noise ratio (PSNR) (16.3645) and structural similarity (SSIM) (0.9067) values, ensuring superior noise reduction and structural preservation. The results demonstrate that the effectiveness of high-resolution ISAR imaging in accurately detecting and characterizing drone swarms pave the way for enhanced airspace security measures.Article Citation - WoS: 1Citation - Scopus: 1Solving an initial boundary value problem on the semiinfinite interval(Tubitak Scientific & Technological Research Council Turkey, 2016) Atalan, Ferihe; Guseinov, Gusein Sh.We explore the sign properties of eigenvalues and the basis properties of eigenvectors for a special quadratic matrix polynomial and use the results obtained to solve the corresponding linear system of differential equations on the half line subject to an initial condition at t = 0 and a condition at t = infinity.Article Citation - WoS: 12Citation - Scopus: 12A Polarity Calculation Approach for Lexicon-Based Turkish Sentiment Analysis(Tubitak Scientific & Technological Research Council Turkey, 2019) Yurtalan, Gökhan; Koyuncu, Murat; Turhan, ÇiğdemSentiment analysis attempts to resolve the senses or emotions that a writer or speaker intends to send across tothe people about an object or event. It generally uses natural language processing and/or artificial intelligence techniquesfor processing electronic documents and mining the opinion specified in the content. In recent years, researchers haveconducted many successful sentiment analysis studies for the English language which consider many words and wordgroups that set emotion polarities arising from the English grammar structure, and then use datasets to test theirperformance. However, there are only a limited number of studies for the Turkish language, and these studies have lowerperformance results compared to those studies for English. The reasons for this can be incorrect translation of datasetsfrom English into Turkish and ignoring the special grammar structures in the latter. In this study, special Turkish wordsand linguistic constructs which affect the polarity of a sentence are determined with the aid of a Turkish linguist, and anappropriate lexicon-based polarity determination and calculation approach is introduced for this language. The proposedmethodology is tested using different datasets collected from Twitter, and the test results show that the proposed systemachieves better accuracy than the previously developed lexical-based sentiment analysis systems for Turkish. The authorsconclude that especially analysis of word groups increases the overall performance of the system significantly.Article Citation - WoS: 9Citation - Scopus: 10Impact of Hospital-Acquired Acute Kidney Injury on Covid-19 Outcomes in Patients With and Without Chronic Kidney Disease: a Multicenter Retrospective Cohort Study(Tubitak Scientific & Technological Research Council Turkey, 2021) Ozturk, Savas; Turgutalp, Kenan; Arıcı, Mustafa; Çetinkaya, Hakkı; Altıparmak, Mehmet Rıza; Aydın, Zeki; Ateş, Kenan; Dolarslan, Mursıde Esra; Seyahi, Nurhan; Yıldız, Alaattın; Bora, FeyzaBackground/aim: Hospital-acquired acute kidney injury (HA-AKI) may commonly develop in Covid-19 patients and is expected to have higher mortality. There is little comparative data investigating the effect of HA-AKI on mortality of chronic kidney disease (CKD) patients and a control group of general population suffering from Covid-19. Materials and methods: HA-AKI development was assessed in a group of stage 3–5 CKD patients and control group without CKD among adult patients hospitalized for Covid-19. The role of AKI development on the outcome (in-hospital mortality and admission to the intensive care unit [ICU]) of patients with and without CKD was compared. Results: Among 621 hospitalized patients (age 60 [IQR: 47–73]), women: 44.1%), AKI developed in 32.5% of the patients, as stage 1 in 84.2%, stage 2 in 8.4%, and stage 3 in 7.4%. AKI developed in 48.0 % of CKD patients, whereas it developed in 17.6% of patients without CKD. CKD patients with HA-AKI had the highest mortality rate of 41.1% compared to 14.3% of patients with HA-AKI but no CKD (p < 0.001). However, patients with AKI+non-CKD had similar rates of ICU admission, mechanical ventilation, and death rate to patients with CKD without AKI. Adjusted mortality risks of the AKI+non-CKD group (HR: 9.0, 95% CI: 1.9–44.2) and AKI+CKD group (HR: 7.9, 95% CI: 1.9–33.3) were significantly higher than that of the non-AKI+non-CKD group. Conclusion: AKI frequently develops in hospitalized patients due to Covid-19 and is associated with high mortality. HA-AKI has worse outcomes whether it develops in patients with or without CKD, but the worst outcome was seen in AKI+CKD patients.Key words: Acute kidney injury, chronic kidney disease, Covid-19, hospitalization, mortality
