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  • Article
    Citation - WoS: 53
    Citation - Scopus: 54
    Forward and Reverse Bias Current-Voltage Characteristics of Au/N-si Schottky Barrier Diodes With and Without Sno2 Insulator Layer
    (Elsevier, 2011) Gokcen, M.; Altindal, S.; Karaman, M.; Aydemir, U.; Altndal, S.
    The effects of interfacial insulator layer, interface states (N-ss) and series resistance (R-s) on the electrical characteristics of Au/n-Si structures have been investigated using forward and reverse bias current-voltage (I-V) characteristics at room temperature. Therefore, Au/n-Si Schottky barrier diodes (SBDs) were fabricated as SBDs with and without insulator SnO2 layer to explain the effect of insulator layer on main electrical parameters. The values of ideality factor (n), R-s and barrier height (Phi(Bo)) were calculated from ln(I) vs. V plots and Cheung methods. The energy density distribution profile of the interface states was obtained from the forward bias I-V data by taking bias dependence of ideality factor, effective barrier height (Phi(e)) and R-s into account for MS and MIS SBDs. It was found that N-ss values increase from at about mid-gap energy of Si to bottom of conductance band edge of both SBDs and the MIS SBD's N-ss values are 5-10 times lower than those of MS SBD's. An apparent exponential increase from the mid-gap towards the bottom of conductance band is observed for both SBDs' (MS and MIS) interface states obtained without taking R-s into account. (C) 2011 Elsevier B.V. All rights reserved.
  • Editorial
    Citation - WoS: 47
    Citation - Scopus: 47
    Emergency Changes in International Guidelines on Treatment for Head and Neck Cancer Patients During the Covid-19 Pandemic
    (Elsevier, 2020) Chaves, Aline Lauda Freitas; Castro, Ana Ferreira; Marta, Gustavo Nader; Junior, Gilberto Castro; Ferris, Robert L.; Giglio, Raul Eduardo; Kowalski, Luiz Paulo
    [No Abstract Available]
  • Book Part
    Clinical Development of Quinone-Based Drugs
    (Elsevier, 2024) Altuner, E.E.; Issa, G.; Ozalp, V.C.; Aldemir, O.; Torlak, Y.; Dar, U.A.
    This chapter provides a detailed explanation of the clinical investigations, pharmacological effects, and characteristics of quinone and quinone derivatives, along with references to pertinent sources. Although quinones have an oxygen group in their structure, they are quickly oxidized and interact with reactive oxygen species. This demonstrates how quinones work as drugs. Quinones and their derivatives are used as medications to treat a wide range of diseases, including cancer, lung, kidney, brain, and tumor disorders. Each of the following has effects on a different area of health; lapochols, anthraquinones, naphthoquinone and its derivatives, and other wide range of quinone derivatives are thoroughly explored in this chapter. © 2025 Elsevier Inc. All rights reserved.
  • Article
    Citation - WoS: 39
    Citation - Scopus: 44
    A Novel Treatment Strategy for Preterm Birth: Intra-Vaginal Progesterone-Loaded Fibrous Patches
    (Elsevier, 2020) Cam, Muhammet Emin; Hazar-Yavuz, Ayse Nur; Cesur, Sumeyye; Ozkan, Ozan; Alenezi, Hussain; Sasmazel, Hilal Turkoglu; Edirisinghe, Mohan; Turkoglu Sasmazel, Hilal
    Progesterone-loaded poly(lactic) acid fibrous polymeric patches were produced using electrospinning and pressurized gyration for infra-vaginal application to prevent preterm birth. The patches were intravaginally inserted into rats in the final week of their pregnancy, equivalent to the third trimester of human pregnancy. Maintenance tocolysis with progesterone-loaded patches was elucidated by recording the contractile response of uterine smooth muscle to noradrenaline in pregnant rats. Both progesterone-loaded patches indicated similar results from release and thermal studies, however, patches obtained by electrospinning had smaller average diameters and more uniform dispersion compared to pressurized gyration. Patches obtained by pressurized gyration had better results in production yield and tensile strength than electrospinning; thereby pressurized gyration is better suited for scaled-up production. The patches did not affect cell attachment, viability, and proliferation on Vero cells negatively. Consequently, progesterone-loaded patches are a novel and successful treatment strategy for preventing preterm birth.
  • Article
    Citation - WoS: 19
    Citation - Scopus: 19
    Metagenomic and Chemical Analysis of Tarhana During Traditional Fermentation Process
    (Elsevier, 2021) Soyucok, Ali; Yurt, Mediha Nur Zafer; Altunbas, Osman; Ozalp, Veli Cengiz; Sudagidan, Mert; Zafer Yurt, Mediha Nur
    Tarhana is one of the favourable traditional fermented food consumed as a soup. Different flour, vegetables, spices and yogurt are main constituents and they compose of microbiota of Tarhana. In this study, bacterial communities in each fermentation process and in their constituents were identified by metagenomic analysis. Also, chemical properties (pH, acidity, salt content and dry matter) were analysed in each step. The results showed that in the dough formation, mainly Lactobacillus, Bacillus, Enterococcus and Streptococcus were present and after Day 4, Clostridium and Bacillus became dominant, after drying Clostridium disappeared and in the final product bacterial communities from Bacillus and Streptococcus genus were observed. Chemical analysis showed that pH decreased from 4.94 to 4.46, acidity increased by time at the beginning of fermentation from 7.5% to 22.5% in first 6 days period, then, became stable at 14% in drying process. Salt content increased by time from 1.74 to 3.08 g salt/100 g Tarhana in first 8 days and in drying process salt content was recorded as 2.81-2.90 and dry matter was obtained as 94 g dry matter/100 g Tarhana in the final product. This study elucidated the effects of ingredients, raw materials and how microbiota and chemical properties changes during fermentation steps of home-made traditional Tarhana production and thus preparation methods could be developed to obtain standardized Tarhana products for industrial production in future.
  • Article
    Citation - WoS: 19
    Citation - Scopus: 21
    Lyapunov Type Inequalities for Mixed Nonlinear Riemann-Liouville Fractional Differential Equations With a Forcing Term
    (Elsevier, 2017) Agarwal, Ravi P.; Ozbekler, Abdullah
    In this paper, we present some new Lyapunov and Hartman type inequalities for Riemann-Liouville fractional differential equations of the form ((a)D(alpha)x)(t) + p(t) vertical bar x(t) vertical bar(mu-1) x(t) + q(t) vertical bar x(t) vertical bar(gamma-1) x(t) = f(t), where p, q, f are real-valued functions and 0 < gamma < 1 < mu < 2. No sign restrictions are imposed on the potential functions p, q and the forcing term f. The inequalities obtained generalize and compliment the existing results for the special cases of this equation in the literature. (C) 2016 Elsevier B.V. All rights reserved.
  • Article
    Citation - WoS: 51
    Citation - Scopus: 54
    Recrystallization and Grain Growth Kinetics of In718 Manufactured by Laser Powder Bed Fusion
    (Elsevier, 2022) Dogu, Merve Nur; Davut, Kemal; Obeidi, Muhannad Ahmed; Yalcin, Mustafa Alp; Gu, Hengfeng; Low, Thaddeus Song En; Brabazon, Dermot
    The recrystallization and grain growth behaviour of IN718 alloy additively manufactured by laser powder bed fusion (L-PBF) is presented herein. The effects of three different temperatures (1050, 1150 and 1250 degrees C) and holding times (15, 45 and 90 min) were investigated. The texture evolution of the samples was recorded via electron backscatter diffraction (EBSD). The as-built sample is composed of bowl-shaped melt pools, a chessboard-like grain pattern and has a cube texture {100}<001>. Recrystallized grains were observed in the samples treated at 1150 degrees C for 15 min, as well as the samples treated for longer periods and at higher temperatures. Recrystallization was observed to start from high dislocation density regions, including the overlapping melt pools and the borders of the chessboard-like pattern. The initial cube texture transforms into a first-generation cube-twin texture {122}<212> via a twinning-assisted recrystallization mechanism. Then, those recrystallization nuclei sweep through the high defect density matrix; during which almost no new twins are formed. The samples treated at 1250 degrees C are almost completely recrystallized, which forms a weaker cube texture and a stronger P-orientation {011}<112>. However, the growth of recrystallized grains is very limited due to the presence of non-coherent precipitates. (C) 2022 The Author(s). Published by Elsevier B.V.
  • Article
    Citation - WoS: 25
    Citation - Scopus: 28
    Effect of Solution Heat Treatment on the Microstructure and Crystallographic Texture of In939 Fabricated by Powder Bed Fusion-Laser Beam
    (Elsevier, 2023) Dogu, Merve Nur; Ozer, Seren; Yalcin, Mustafa Alp; Davut, Kemal; Bilgin, Guney Mert; Obeidi, Muhannad Ahmed; Brabazon, Dermot
    The effect of various solution heat treatment temperatures (i.e., 1120, 1160, 1200 and 1240 & DEG;C) on the microstructure, grain morphology and crystallographic texture of IN939 fabricated by powder bed fusion-laser beam (PBF-LB) was investigated. Microstructural analyses showed that the high-temperature gradient and rapid solidification of the PBF-LB processing caused different resulting microstructures compared to conventionally pro-duced counterparts. The melt pool morphologies and laser scanning paths were examined in the as-fabricated samples in the XZ-and XY-planes, respectively. After the application of solution heat treatment at 1120 & DEG;C, the as-fabricated PBF-LB initial microstructure was still apparent. For solution heat treatments of 1200 & DEG;C and above, the melt pool and scanning path morphologies disappeared and converted into a mixture of columnar grains in the XZ-plane and equiaxed grains in the XY-plane. On the other hand, large equiaxed grains were observed when the samples were solutionized at 1240 & DEG;C. Additionally, g' phase precipitated within the matrix after all solution heat treatment conditions, which led to increase in the microhardness values. According to electron backscatter diffraction (EBSD) analyses, both as-fabricated and solution heat-treated samples had intense texture with {001} plane normal parallel to the building direction. The first recrystallized grains began to appear when the samples were subjected to the solution heat treatment at 1160 & DEG;C and the fraction of the recrystallized grains increased with increasing temperature, as supported by kernel average misorientation (KAM) and grain spread orientation (GOS) analyses.& COPY; 2023 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
  • Article
    Citation - WoS: 45
    Citation - Scopus: 51
    On the lifetime behavior of a discrete time shock model
    (Elsevier, 2013) Eryilmaz, Serkan
    In this article, we study a shock model in which the shocks occur according to a binomial process, i.e. the interarrival times between successive shocks follow a geometric distribution with mean 1/p. According to the model, the system fails when the time between two consecutive shocks is less than a prespecified level. This is the discrete time version of the so-called delta-shock model which has been previously studied for the continuous case. We obtain the probability mass function and probability generating function of the system's lifetime. We also present an extension of the results to the case where the shock occurrences are dependent in a Markovian fashion. (C) 2012 Elsevier B.V. All rights reserved.
  • Article
    Citation - WoS: 44
    Citation - Scopus: 61
    Impact of Physical Ambiance on Communication, Collaboration and Coordination in Agile Software Development: an Empirical Evaluation
    (Elsevier, 2012) Mishra, Deepti; Mishra, Alok; Ostrovska, Sofiya
    Context: Communication, collaboration and coordination are key enablers of software development and even more so in agile methods. The physical environment of the workspace plays a significant role in effective communication, collaboration, and coordination among people while developing software. Objective: In this paper, we have studied and further evaluated empirically the effect of different constituents of physical environment on communication, coordination, and collaboration, respectively. The study aims to provide a guideline for prospective agile software developers. Method: A survey was conducted among software developers at a software development organization. To collect data, a survey was carried out along with observations, and interviews. Results: It has been found that half cubicles are 'very effective' for the frequency of communication. Further, half cubicles were discovered 'effective' but not 'very effective' for the quality/effectiveness of communication. It is found that half-height cubicles and status boards are 'very effective' for the coordination among team members according to the survey. Communal/discussion space is found to be 'effective' but not 'very effective' for coordination among team members. Our analysis also reveals that half-height glass barriers are 'very effective' during the individuals problem-solving activities while working together as a team. Infact, such a physically open environment appears to improve communication, coordination, and collaboration. Conclusion: According to this study, an open working environment with only half-height glass barriers and communal space plays a major role in communication among team members. The presence of status boards significantly help in reducing unnecessary communication by providing the required information to individuals and therefore, in turn reduce distractions a team member may confront in their absence. As communication plays a significant role in improving coordination and collaboration, it is not surprising to find the effect of open working environment and status boards in improving coordination and collaboration. An open working environment increases the awareness among software developers e.g. who is doing what, what is on the agenda, what is taking place, etc. That in turn, improves coordination among them. A communal/discussion space helps in collaboration immensely. (C) 2012 Elsevier B.V. All rights reserved.