153 results
Search Results
Now showing 1 - 10 of 153
Conference Object Citation - WoS: 5Citation - Scopus: 3Evaluation of Efficiencies of Diffuse Allochthonous and Autochthonous Nutrient Input Control in Restoration of a Highly Eutrophic Lake(I W A Publishing, 2002) Muhammetoglu, A; Muhammetoglu, H; Soyupak, SMogan Lake is an important recreational area for Metropolitan Ankara-Turkey. It is a shallow eutrophic lake with a dense growth of macrophytes. The main contributors of nutrients and other pollutants to the lake are the creeks carrying the runoff water from the watershed and upland farming land, in addition to the domestic and industrial wastewater discharges from a nearby town and industries. Hydrodynamic and water quality modeling techniques were used to determine the optimum management schemes for the lake restoration and diffuse pollution control. Management scenarios were devised and tested to control allochthonous and autochthonous nutrient inputs to the lake. Phosphorus and nitrogen load reductions were the main test elements for the control of allochthonous nutrient inputs. The scenario analysis revealed that reduction of phosphorus and nitrogen loads from diffused sources will have a marginal effect on controlling eutrophication if macrophyte growth is left uncontrolled. Scenarios employing macrophyte harvesting and sediment dredging have been evaluated for autochthonous nutrient input control. Sediment dredging alone has been shown to yield the most favorable conditions for water quality improvement in Mogan Lake. Further, control of diffuse pollution was an essential final step to achieve an acceptable long-term sustainable water quality improvement in the lake.Article Citation - WoS: 102Citation - Scopus: 113A 1.6-Mm, Metal Tube Ultrasonic Motor(Ieee-inst Electrical Electronics Engineers inc, 2003) Cagatay, S; Koc, B; Uchino, KA miniaturized metal tube ultrasonic motor, the dimensions of which are 1.6 mm in diameter and 6 rum in length, was developed. Two flattened surfaces with 90-degrees were ground on the outer surface of the stator. Two PZT-based piezoelectric ceramics were bonded onto these flat surfaces. The asymmetrical surface of the stator developed the split of the two degenerated orthogonal bending modes, resulting in a wobble motion. The working frequency of the 1.6-mm motor with 6 mm in length was 130 kHz. A torque of 0.5 mNm was reached at a maximum power of 45 mW with a speed of 45 rad/sec. The maximum efficiency was 16%.Article Citation - WoS: 29Citation - Scopus: 33Health Literacy of Nursing Students and Its Effective Factors(Wiley-hindawi, 2019) Ozen, Nurten; Ozkaptan, Bilge Bal; Coskun, Sabahat; Terzioglu, FusunBackground The insufficiency of health literacy negatively affects the national economy as it leads to increased health service expenditure. It is very important for individuals to have accurate health-related information to reduce these negative effects. Aim The aim of the study is to examine the health literacy of nursing students and its effective factors. Methods This descriptive study was carried out with students from the nursing department of a vocational school of health sciences between September and October 2018 in Turkey. A semi-structured questionnaire regarding the descriptive features of the participants and the European Health Literacy Scale were used for data collection. Results The study included 283 nursing students; 29.3% had a problematic-limited health literacy level. The study found a statically significant difference between student year, high school graduation and family's income level and the total mean score of the HLS-EU scale. Conclusion The subject of health literacy should be integrated into the educational program of nursing students. The nurses are the most important workforce in health services, and awareness about this subject should be raised.Article Citation - WoS: 22Citation - Scopus: 22The impact of the using high-fidelity simulation and standardized patients to management of postpartum hemorrhage in undergraduate nursing students: A randomized controlled study in Turkey(Taylor & Francis inc, 2019) Karadas, Merve Mert; Terzioglu, FusunWe examined the efficiency of different simulation methods for the improvement of knowledge and skills of nursing students in the management of postpartum hemorrhage. A total of 84 nursing students participated in the study. Data were obtained using a Semi-Structured Questionnaire Form, Student Satisfaction Evaluation Form, Effective Communication Skills Checklist, Spielberger's State-Trait Anxiety Inventory, and Skills Evaluation Form for Postpartum Bleeding Management. We suggest that the use of different simulation methods may be effective in improving the knowledge and skills of nursing students in the management of postpartum hemorrhage.Article Citation - WoS: 19Citation - Scopus: 20The consumers' social media use in choosing physicians and hospitals: the case study of the province of Izmir(Wiley, 2017) Tengilimoglu, Dilaver; Sarp, Nilgn; Yar, Cemre Eda; Bektas, Meral; Hidir, Mehmet Nil; Korkmaz, EsinManifested as a reflection of the Internet technology progress, web 2.0 has transformed communication among people to different dimensions while increasing the social use of Internet. Thus, the concept of social media has entered our lives. Blogs, forums, Facebook, Twitter and YouTube applications are but few of the social media platforms with active users exceeding millions. As in many other subjects, these and others are also environments where people share information and their positive or negative experiential views with respect to healthcare issues and services. Hence, the social media communication and exchange of information are deemed influential on the process of receiving health services. In the present study that aims to determine social media use of individuals in their choice of physicians, dentists and hospitals, a survey, as a data collection instrument, has been carried out to 947 residents of the province of Izmir. Individuals participating in the study have stated that they have used social media in choosing a physician (41.9% of the participants), dentist (34.1% of the participants) and hospitals (41.7% of the participants). The study has revealed that individuals are affected by social media in their healthcare choices. Copyright (C) 2015 John Wiley & Sons, Ltd.Article Citation - WoS: 8Citation - Scopus: 6A platinum blue complex exerts its cytotoxic activity via DNA damage and induces apoptosis in cancer cells(Wiley, 2017) Adiguzel, Zelal; Ozalp-Yaman, Seniz; Celik, Gokalp; Salem, Safia; Bagci-Onder, Tugba; Senbabaoglu, Filiz; Acilan, CeydaHere, we describe the characteristics of a Pt-blue complex [Pt-4(2-atp)(8)(H2O)(OH)] (2-atp: 2-aminothiophenol) as a prodrug for its DNA-binding properties and its use in cancer therapy. The nature of the interaction between the Pt-blue complex and DNA was evaluated based on spectroscopic measurements, the electronic absorption spectra, thermal behavior, viscosity, fluorometric titration, and agarose gel electrophoresis. Our results suggested that the compound was able to partially intercalate DNA and appeared to induce both single- and double-stranded breaks (DBS) on DNA in vitro, but no DSBs in cells. The ability of the compound to induce DNA damage was dependent on reactive oxygen species (ROS) in vitro. There was also elevated formation of ROS and SOD expression in response to drug treatment in cell culture. The complex was found to be more cytotoxic to cancer cells in comparison with noncancer controls using WST-1 assay. The mean of cell death was determined to be apoptosis as assessed via biochemical, morphological, and molecular observations, including DNA condensation/fragmentation analysis, live cell imaging microscopy, TUNEL analyses, and increase in the levels of pro-apoptotic genes such as Bag3, Bak, Bik, Bmf, and Hrk. Hence, the Pt-blue complex under study grants premise for further studies.Article Citation - WoS: 68Citation - Scopus: 91The Potential Medicinal Value of Plants From Asteraceae Family With Antioxidant Defense Enzymes as Biological Targets(Taylor & Francis Ltd, 2015) Koc, Suheda; Isgor, Belgin S.; Isgor, Yasemin G.; Moghaddam, Naznoosh Shomali; Yildirim, OzlemContext: Plants and most of the plant-derived compounds have long been known for their potential pharmaceutical effects. They are well known to play an important role in the treatment of several diseases from diabetes to various types of cancers. Today most of the clinically effective pharmaceuticals are developed from plant-derived ancestors in the history of medicine. Objective: The aim of this study was to evaluate the free radical scavenging activity and total phenolic and flavonoid contents of methanol, ethanol, and acetone extracts from flowers and leaves of Onopordum acanthium L., Carduus acanthoides L., Cirsium arvense (L.) Scop., and Centaurea solstitialis L., all from the Asteraceae family, for investigating their potential medicinal values of biological targets that are participating in the antioxidant defense system such as catalase (CAT), glutathione S-transferase (GST), and glutathione peroxidase (GPx). Materials and methods: In this study, free radical scavenging activity and total phenolic and flavonoid contents of the plant samples were assayed by DPPH, Folin-Ciocalteu, and aluminum chloride colorimetric methods. Also, the effects of extracts on CAT, GST, and GPx enzyme activities were investigated. Results and discussion: The highest phenolic and flavonoid contents were detected in the acetone extract of C. acanthoides flowers, with 90.305 mg GAE/L and 185.43 mg Q/L values, respectively. The highest DPPH radical scavenging was observed with the methanol leaf extracts of C. arvense with an IC50 value of 366 ng/mL. The maximum GPx and GST enzyme inhibition activities were observed with acetone extracts from the flower of C. solstitialis with IC50 values of 79 and 232 ng/mL, respectively.Article Citation - WoS: 47Citation - Scopus: 52Biocompatible Electroactive Tetra(aniline)-Conjugated Peptide Nanofibers for Neural Differentiation(Amer Chemical Soc, 2018) Arioz, Idil; Erol, Ozlem; Bakan, Gokhan; Dikecoglu, F. Begum; Topal, Ahmet E.; Urel, Mustafa; Guler, Mustafa O.Peripheral nerve injuries cause devastating problems for the quality of patients' lives, and regeneration following damage to the peripheral nervous system is limited depending on the degree of the damage. Use of nanobiomaterials can provide therapeutic approaches for the treatment of peripheral nerve injuries. Electroactive biomaterials, in particular, can provide a promising cure for the regeneration of nerve defects. Here, a supramolecular electroactive nanosystem with tetra(aniline) (TA)-containing peptide nanofibers was developed and utilized for nerve regeneration. Self-assembled TA conjugated peptide nanofibers demonstrated electroactive behavior. The electroactive self-assembled peptide nanofibers formed a well-defined three-dimensional nanofiber network mimicking the extracellular matrix of the neuronal cells. Neurite outgrowth was improved on the electroactive TA nanofiber gels. The neural differentiation of PC-12 cells was more advanced on electroactive peptide nanofiber gels, and these biomaterials are promising for further use in therapeutic neural regeneration applications.Review Citation - WoS: 16Citation - Scopus: 20Assessing the Coverage of E-Health Services in Sub-Saharan Africa a Systematic Review and Analysis(Georg Thieme verlag Kg, 2017) Adeloye, Davies; Adigun, Taiwo; Misra, Sanjay; Omoregbe, NicholasBackground: E-Health has attracted growing interests globally. The relative lack of facilities, skills, funds and information on existing e-Health initiatives has affected progress on e-Health in Africa. Objectives: To review publicly available literature on e-Health in sub-Saharan Africa (sSA) towards providing information on existing and ongoing e-Health initiatives in the region. Methods: Searches of relevant literature were conducted on Medline, EMBASE and Global Health, with search dates set from 1990 to 2016. We included studies on e-Health initiatives (prototypes, designs, or completed projects) targeting population groups in sSA. Results: Our search returned 2322 hits, with 26 studies retained. Included studies were conducted in 14 countries across the four sub-regions in sSA (Central, East, South and West) and spreading over a 12-year period, 2002-2014. Six types of e-Health interventions were reported, with 17 studies (65%) based on telemedicine, followed by mHealth with 5 studies (19%). Other e-Health types include expert system, electronic medical records, e-mails, and online health module. Specific medical specialties covered include dermatology (19%), pathology (12%) and radiology (8%). Successes were 'widely reported' (representing 50% overall acceptance or positive feedbacks in a study) in 10 studies (38%). The prominent challenges reported were technical problems, poor inter net and connectivity, participants' selection biases, contextual issues, and lack of funds. Conclusion: E-Health is evolving in sSA, but with poorly published evidence. While we call for more quality research in the region, it is also important that population-wide policies and on-going e-Health initiatives are contextually feasible, acceptable, and sustainable.Article Citation - WoS: 10Alkaline Hydrothermal Synthesis, Characterization, and Photocatalytic Activity of Tio2 Nanostructures: the Effect of Initial Tio2 Phase(Amer Scientific Publishers, 2019) Erdogan, Nursev; Park, Jongee; Choi, Woohyuk; Kim, Soo Young; Ozturk, AbdullahOne-dimensional (1D) titanate nanostructures were synthesized by hydrothermal route, using commercially available TiO2 (P25) and anatase powders as precursor materials and strong NaOH solution as catalyzer. The prepared titanates were calcined, followed by protonation to produce TiO2 nanostructures having enhanced photocatalytic and photovoltaic properties. The synthesized TiO2 1D nanostructures were characterized using field-emission scanning electron microscope, high-resolution electron microscope, X-ray diffraction analysis, and UV-Vis photospectroscopy to understand the effect of initial TiO2 phase on morphological and crystallographic features, and bandgap. Methylene blue degradation test was applied to evaluate the photoactivity of the products obtained after different stages of the process. The findings indicate that 1D TiO2 nanostructures form by different mechanisms from dissolved aggregates during hydrothermal process, depending on the crystal structure of the initial precursor used. Photocatalytic test results reveal that protonated titanates have considerable adsorption capability, while photocatalytic degradation depends on TiO2 transformation.
