1330 results
Search Results
Now showing 1 - 10 of 1330
Article Nonspesifik Kronik Boyun Ağrısı Olan Akademik Personelde İleri Baş Postürünü Etkileyen Faktörlerin Karşılaştırılması: Tanımlayıcı Çalışma(2024) Yelvar, Gul Deniz Yilmaz; Cirak, Yasemin Buran; Begen, Sena Nur; Arslan, Fatma Cansu Aktaş; Uluğ, Naime; Kılıç, ErdenAmaç: Çalışmanın amacı, nonspesifik kronik boyun ağrısı olan akademik personelde ileri baş pozisyonuna etkileyen faktörlerin karşı laştırılmasıdır. Gereç ve Yöntemler: Bu çalışmaya, nonspesifik kronik boyun ağrısı olan elli katılımcı dâhil edildi. Katılımcılar, kranioverteb ral açı değerine göre “normal servikal pozisyon” ve “ileri baş du ruşu(FHP+)” olmak üzere iki gruba ayrıldı. Demografik bilgiler ve oturma, bilgisayar ve telefon kullanım süresi kaydedildi. Dinlenme, uyku ve aktivasyon sırasındaki ağrı şiddeti, görsel analog skalası kul lanılarak değerlendirildi. Üst trapezius ve suboksipital kaslarının ağrı eşiği algometre ile değerlendirildi. Skapulotorasik kas kuvveti, derin servikal kas kuvvet ve enduransı el dinamometresi ve stabilizer basın çlı biyofeedback ünitesi kullanılarak değerlendirildi. Kraniovertebral açı, fotoğraf analiz yöntemleriyle belirlendi. Servikal eklem pozisyon hissi, dijital inklinometre kullanılarak değerlendirildi. Bulgular: Top lam 50 akademik personel dâhil edildi. FHP+ grubunda kilo, beden kitle indeksi ve cep telefonu kullanım süresi anlamlı olarak daha yük sek olduğu belirlendi (p=0,02; p=0,01). FHP+ grubunda üst trapezius ağrı eşiğinin anlamlı olarak daha yüksek olduğu belirlendi (p=0,02). Gruplar arasında orta trapezius kas kuvveti, derin servikal fleksör kas dayanıklılığı ve eklem pozisyon hissi bakımıdan anlamlı fark olduğu belirlendi. (sırasıyla p=0,02; p=0,03; p=0,01). Sonuç: Nonspesifik boyun ağrısı olan hastalarda, FHP; üst trapezius kas ağrı eşiği, orta tra pezius kas kuvveti, azalmış derin servikal fleksör kas dayanıklılığı ve servikal eklem pozisyon hissi ile ilişkilidir.Article Atlas’ın Yükü Adlı Eserinde Hileci Yazar Jeanette Winterson(2021) Adiguzel, Leyla; Tekin, KuğuHileci, İsviçreli psikiyatr Carl Gustav Jung tarafından ilk kez ortaya atılan arketip kavramının önde gelen örneklerinden biridir ve genel olarak bireylerin karakterlerindeki bayağı özellikler olarak tanımlanır. Bununla birlikte çağdaş edebiyatta hileci arketipi; kurnaz, doğruyu söyleyen, hikâye anlatıcısı ve evrenin yasalarıyla oynayan bir dönüştürücü olarak tanımlanmaktadır. Hileci figür, gerçeği körü körüne kabul etmeyi reddeder; modası geçmiş zihniyetin yeri geldiğinde yıkılması gerektiği görüşünü savunur. Yıkıcı tutumuna rağmen kültürlerin tasarımına katkısından dolayı saygı duyulur. Jeanette Winterson’ın Atlas ve Herakles mitini tekrar kaleme aldığı Weight (Atlas’ın Yükü) adlı eseri, 2005 yılında farklı kültürlere ait mitleri tanınmış yazarlara yeniden yazdıran Canongate Myth Series projesi kapsamında yayınlandı. İngiliz edebiyatının önde gelen yazarlarından biri olan Winterson; titizlikle yazdığı hibrit kurgusunda, epik gelenekleri çeşitli edebi araçlar ve farklı türlerin karışımı ile yapı bozuma uğratır. Yazar, çok katmanlı eserinde gerçekte kendisini özdeşleştirdiği mitolojik kahraman Atlas üzerinden hikâyesini anlatır. Bu çalışma, eski miti yeniden kaleme alma sürecinde, kurnaz ve bilge bir dönüştürücü ve öykü anlatıcısı olarak Jeanette Winterson'ın hileci-sanatçı yönüne dikkat çekmeyi amaçlamaktadır.Article Citation - WoS: 1Citation - Scopus: 2The Detailed Transseptal Puncture Technique for Optimal Closure in Patients With a Patent Foramen Ovale(Frontiers Media Sa, 2024) Ilkay, Erdogan; Saricam, Ersin; Kacmaz, Fehmi; Yakici, Aysel; Koca, Cigdem; Ozeke, Ozcan; Onal, Mehmet ZulkufBackground The closure of a patent foramen ovale (PFO) using transseptal puncture has particular advantages and disadvantages. Thus, transseptal puncture should be re-evaluated in detail. Aims We aimed to assess the effectiveness of the detailed transseptal puncture technique in patients who underwent PFO closure due to cryptogenic stroke or transient ischemic attack in terms of residual shunts and atrial fibrillation. Methods We prospectively analyzed 144 consecutive patients who underwent PFO closure by the detailed transseptal puncture technique between February 2013 and April 2023 in two centers. All of the patients had a >10 mm long-tunnel PFO. Results The procedural success rate was 100%. However, after the procedure, moderate pericardial effusion developed in one patient (0.7%) and an acute pulmonary embolism related to femoral vein thrombosis was observed in one patient (0.7%) during the first month. Complications related to the procedure were noted in two patients (1.4%) during the first month of follow-up. Residual shunts were observed in 1.4% of cases after PFO closure. Conclusion We demonstrated that the detailed transseptal technique is safe and effective for PFO closure. The detailed transseptal PFO closure technique significantly reduced the risk of atrial fibrillation, and the occurrence of residual shunts was significantly low following the closure.Article Ab Adalet Divanı’nın Hukuk Yaratması Ultra-vires Tasarruf Olarak Görülebilir Mi?(2021) Arsava, Ayşe FüsunAB Adalet Divanı Taricco II davasında vermiş olduğu kararla İtalyan Anayasa Mahkemesi ile kendi arasındaanayasal kimliğin korunması konusundaki mevcut uyuşmazlığın tırmanmasını önleyebilmiştir. AB Adalet Divanı birönceki kararında İtalyan hukukunun zaman aşımı kurallarının AB’nin Çalışma Usulleri Hakkındaki Sözleşme’nin325. maddesi muvacehesinde uygulanmaması gerektiği sonucuna varmıştır. İtalyan Anayasa Mahkemesi ise budurumu İtalyan Anayasasının kimliğinin korunması ile bağdaşmaz olarak görmüştür. Makalede AB’nin ÇalışmaUsulleri Hakkındaki Sözleşme’nin 325. maddesinin etkisine ilişkin olarak AB Adalet Divanı tarafından getirilengerekçelere ve Taricco I kararında getirilen AB Adalet Divanının hukuk yaratma sınırlarına ışık tutulmaktadır.Article W-Band RCS Prediction of Small Objects: Comparing Two Widely Used Methods with Experimental Validation(Gazi University, 2025) Kara, Ali; Aydın, Elif; Yardım, Funda Ergün; Sezgin, DenizThis paper compares the accuracy of Shooting and Bouncing Rays and Electric Field Integral Equation methods for Radar Cross Section prediction of small objects at 77-81 GHz band. Existing studies on RCS prediction methods often lack comprehensive comparisons between computational and experimental results, particularly for small objects measured with a 77 GHz radar. This study addresses this gap by presenting an in-depth analysis of both simulation and measurement data. In this work, three targets with varying geometries and materials were measured with a frequency modulated continuous wave radar and simulated using Ansys HFSS and CST Studio Suite. The measurements were performed with a commercial off-the-shelf (COTS) frequency modulated continuous wave radar operating at 77–81 GHz. This study aims to emphasize the importance of considering both efficiency and accuracy when opting for an RCS prediction method. Overall, the outcomes of both methods have largely demonstrated good alignment. It has been noted that, while Shooting and Bouncing Rays method offers promising time-saving advantages, Electric Field Integral Equation method remains a valuable tool for complex geometries where precise results are crucial.Article Citation - WoS: 7Citation - Scopus: 10Comparison of Three Different Learning Methods of Multilayer Perceptron Neural Network for Wind Speed Forecasting(Gazi Univ, 2021) Bulut, Mehmet; Tora, Hakan; Buaisha, Dr.magdiIn the world, electric power is the highest need for high prosperity and comfortable living standards. The security of energy supply is an essential concept in national energy management. Therefore, ensuring the security of electricity supply requires accurate estimates of electricity demand. The share of electricity generation from renewables is significantly growing in the world. This kind of energy types are dependent on weather conditions as the wind and solar energies. There are two vital requirements to locate and measure specific systems to utilize wind power: modelling and forecasting of the wind velocity. To this end, using only 4 years of measured meteorological data, the present research attempts to estimate the related speed of wind within the Libyan Mediterranean coast with the help of ANN (artificial neural networking) with three different learning algorithms, which are Levenberg-Marquardt, Bayesian Regularization and Scaled Conjugate Gradient. Conclusions reached in this study show that wind speed can be estimated within acceptable limits using a limited set of meteorological data. In the results obtained, it was seen that the SCG algorithm gave better results in tests in this study with less data.Article Citation - WoS: 37Citation - Scopus: 45Study on the Cytocompatibility, Mechanical and Antimicrobial Properties of 3d Printed Composite Scaffolds Based on Pva/ Gold Nanoparticles (aunp)/ Ampicillin (amp) for Bone Tissue Engineering(Elsevier, 2021) Topsakal, Aysenur; Midha, Swati; Yuca, Esra; Tukay, Ari; Sasmazel, Hilal Turkoglu; Kalaskar, Deepak M.; Gunduz, OguzhanOver the years, gold nanoparticles (AuNP) have been widely used in several biomedical applications related to the diagnosis, drug delivery, bio-imaging, photo-thermal therapy and regenerative medicine, owing to their unique features such as surface plasmon resonance, fluorescence and easy surface functionality. Recent studies showed that gold nanoparticles display positive effect on osteogenic differentiation. In line with this effect, 3-Dimesional (3D) scaffolds that can be used in bone tissue were produced by exploiting the properties of gold nanoparticles that increase biocompatibility and support bone tissue development. In addition, ampicillin was added to the scaffolds containing gold nanoparticles as a model drug to improve its antimicrobial properties. The scaffolds were produced as composites of polyvinyl alcohol (PVA) main matrix as PVA, PVA/AuNP, PVA/Ampicillin (AMP) and PVA/AuNP/AMP. Scanning Electron Microscopy (SEM) Fourier Transform Infrared Spectroscopy (FTIR), tensile measurement tests, and in vitro applications of 3D scaffolds were performed. As depicted by SEM, scaffolds were produced at pore sizes appropriate for bone tissue regeneration. According to FTIR results, there was no modification observed in the AMP, PVA and gold nanoparticles due to mixing in the resultant scaffolds. In vitro results show that 3D printed composite scaffold based on PVA/AuNP/AMP are biocompatible, osteo-inductive and exhibit antimicrobial properties, compared to PVA scaffolds. This study has implications for addressing infections during orthopedic surgeries. The PVA-based gold nanoparticle 3D tissue scaffold study containing ampicillin covers a new study compared to other articles based on gold nanoparticles.Book Non-Discrimination in Turkey(Springer International Publishing, 2022) Yilmaz,G.The book “Non-discrimination in Turkey” focuses on issue areas within the broader non-discrimination framework in Turkey. It looks domestic change in Turkey regarding non-discrimination across time. The book unpacks the principle of non-discrimination and provides analysis in many issue areas like LGBTI rights, disability rights or age discrimination that rely under the framework of non-discrimination. Adopting a comprehensive approach including many areas within non-discrimination, the book will be useful for the students, scholars and researchers of international relations, political science, Middle East and Turkish studies and those interested in human rights. © The Editor(s)(if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022.Editorial Citation - WoS: 5Citation - Scopus: 6Transcatheter Treatment Tricuspid Regurgitation by Valve-In Implantation With a Novel Balloon-Expandable Myval® Thv(Polish Cardiac Soc-polskie Towarzystwo Kardiologiczne, 2022) Ayhan, Huseyin; Karaduman, Bilge Duran; Keles, Telat; Bozkurt, Engin[No Abstract Available]Article Citation - WoS: 2Citation - Scopus: 22-Ag and Bone Marrow-Targeted Pcl Nanoparticles as Nanoplatforms for Hematopoietic Cell Line Mobilization(Bmc, 2024) Kose, Sevil; Varan, Cem; Onen, Selin; Nemutlu, Emirhan; Bilensoy, Erem; Korkusuz, PetekBackgroundThe use of mobilizing agents for hematopoietic stem cell (HSC) transplantation is insufficient for an increasing number of patients. We previously reported lipid made endocannabinoid (eCB) ligands act on the human bone marrow (hBM) HSC migration in vitro, lacking long term stability to be therapeutic candidate. In this study, we hypothesized if a novel 2-AG-loaded polycaprolactone (PCL)-based nanoparticle delivery system that actively targets BM via phosphatidylserine (Ps) can be generated and validated.MethodsPCL nanoparticles were prepared by using the emulsion evaporation method and characterized by Zetasizer and scanning electron microscopy (SEM). The encapsulation efficiency and release profile of 2-AG were determined by liquid chromatography-tandem mass spectrometry (LC-MS/MS). The presence of cannabinoid receptors (CBRs) in HSCs and monocytes was detected by flow cytometry. Cell morphology and viability were assessed using transmission electron microscopy (TEM), SEM, and the WST-1 viability assay. The migration efficacy of the 2-AG and 2-AG-loaded nanoparticle delivery system on HSCs and HPSCs (TF-1a and TF-1) and monocytes (THP-1) was evaluated using a transwell migration assay.ResultsThe 140-225 nm PCL nanoparticles exhibited an increasing polydispersity index (PDI) after the addition of Ps and 2-AG, with a surface charge ranging from - 25 to -50 mV. The nanoparticles released up to 36% of 2-AG within the first 8 h. The 2-AG-Ps-PCL did not affect cellular viability compared to control on days 5 and 10. The HSCs and monocytes expressed CB1R and CB2R and revealed increased migration to media containing 1 mu M 2-AG-Ps-PCL compared to control. The migration rate of the HSCs toward monocytes incubated with 1 mu M 2-AG-Ps-PCL was higher than that of the monocytes of control. The 2-AG-Ps-PCL formulation provided a real time mobilization efficacy at 1 mu M dose and 8 h time window via a specific CBR agonism.ConclusionThe newly generated and validated 2-AG-loaded PCL nanoparticle delivery system can serve as a stable, long lasting, targeted mobilization agent for HSCs and as a candidate therapeutic to be included in HSC transplantation (HSCT) protocols following scale-up in vivo preclinical and subsequent clinical trials.
