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Article Citation - WoS: 4Citation - Scopus: 5Space Efficiency in Tall Hotel Towers(Mdpi, 2024) Aslantamer, Ozlem Nur; Ilgin, Huseyin EmreMaximizing spatial utilization within tall buildings stands as a paramount planning consideration for ensuring project feasibility, particularly accentuated ins the context of hotel constructions. To date, no comprehensive study has addressed this issue while considering crucial architectural and structural planning factors. This article fills this gap by using a case study method based on data from 31 contemporary tall hotel towers. The findings revealed several key points: (i) central core typology was mostly utilized; (ii) prismatic buildings were the most prevalent forms; (iii) shear-walled frame systems were predominantly employed; (iv) concrete was the preferred choice for hotel construction; (v) the average space efficiency and the ratio of core area to gross floor area (GFA) averaged 81.2% and 16%, respectively; (vi) the range changed from a minimum of 70% to 4% to a maximum of 94% to 28%; and (vii) space efficiency showed an inverse relationship with the height of the building. It is anticipated that this paper will assist architects and structural engineers as well as builders involved in the planning of hotel developments.Article Citation - WoS: 4Citation - Scopus: 4The Effect of Cerium Oxide (ceo2) on Ischemia-Reperfusion Injury in Skeletal Muscle in Mice With Streptozocin-Induced Diabetes(Mdpi, 2024) Ozer, Abdullah; Sengel, Necmiye; Kucuk, Ayseguel; Yigman, Zeynep; Ozdemir, Cagri; Kilic, Yigit; Arslan, MustafaObjective: Lower extremity ischemia-reperfusion injury (IRI) may occur with trauma-related vascular injury and various vascular diseases, during the use of a tourniquet, in temporary clamping of the aorta in aortic surgery, or following acute or bilateral acute femoral artery occlusion. Mitochondrial dysfunction and increased basal oxidative stress in diabetes may cause an increase in the effects of increased reactive oxygen species (ROS) and mitochondrial dysfunction due to IRI. It is of great importance to examine therapeutic approaches that can minimize the effects of IRI, especially for patient groups under chronic oxidative stress such as DM. Cerium oxide (CeO2) nanoparticles mimic antioxidant enzymes and act as a catalyst that scavenges ROS. In this study, it was aimed to investigate whether CeO2 has protective effects on skeletal muscles in lower extremity IRI in mice with streptozocin-induced diabetes. Methods: A total of 38 Swiss albino mice were divided into six groups as follows: control group (group C, n = 6), diabetes group (group D, n = 8), diabetes-CeO2 (group DCO, n = 8), diabetes-ischemia/reperfusion (group DIR, n = 8), and diabetes-ischemia/reperfusion-CeO2 (group DIRCO, n = 8). The DCO and DIRCO groups were given doses of CeO2 of 0.5 mg/kg intraperitoneally 30 min before the IR procedure. A 120 min ischemia-120 min reperfusion period with 100% O-2 was performed. At the end of the reperfusion period, muscle tissues were removed for histopathological and biochemical examinations. Results: Total antioxidant status (TAS) levels were found to be significantly lower in group DIR compared with group D (p = 0.047 and p = 0.022, respectively). In group DIRCO, total oxidant status (TOS) levels were found to be significantly higher than in group DIR (p < 0.001). The oxidative stress index (OSI) was found to be significantly lower in group DIR compared with group DCO (p < 0.001). Paraoxanase (PON) enzyme activity was found to be significantly increased in group DIR compared with group DCO (p < 0.001). The disorganization and degeneration score for muscle cells, inflammatory cell infiltration score, and total injury score in group DIRCO were found to be significantly lower than in group DIR (p = 0.002, p = 0.034, and p = 0.001, respectively). Conclusions: Our results confirm that CeO2, with its antioxidative properties, reduces skeletal muscle damage in lower extremity IRI in diabetic mice.Article Citation - WoS: 1Citation - Scopus: 2Current New Approach in Thoracoscopic Surgery: Non-Intubated Uniportal Video-Assisted Thoracoscopic Surgery (Ni-Univats)(Mdpi, 2025) Agar, Mehmet; Gulcek, Ilham; Kalkan, Muhammed; Ulutas, Hakki; Celik, Muhammet Reha; Aksu, Ahmet; Cakmak, MuharremBackground and Objectives: Non-intubated uniportal video-assisted thoracoscopic surgery (NI-UniVATS) is a minimally invasive technique performed using a single port, allowing the entire surgical procedure to be completed with spontaneous breathing without the need for general anesthesia. Materials and Methods: This retrospective study included 51 patients who underwent NI-UniVATS between 2020 and 2023. The intraoperative and postoperative data of patients who underwent NI-UniVATS were evaluated. Results: Among the cases, 37 (72.5%) were male, and 14 (46.6%) were female, with a mean age of 47.73 +/- 20.43 years (range: 18-78 years). The mean operative time was 25.92 +/- 7.31 min. No perioperative complications were observed in any patient. The mean postoperative hospital stay was 4.17 +/- 1.76 days (range: 2-9 days). A right hemithoracic approach was performed in 28 patients (54.9%), whereas a left hemithoracic approach was used in 23 patients (45.1%). The procedures performed included wedge resection in 27 patients (52.9%), biopsy in 22 patients (43.1%), pericardial window creation in one patient (2%), and intrathoracic foreign body removal in one patient (2%). Conclusions: NI-UniVATS allows for safer surgery by preventing the adverse effects and complications associated with general anesthesia. NI-UniVATS can be recommended as a safe and feasible approach for both minor and major thoracic procedures.Article Citation - WoS: 7Citation - Scopus: 8Evaluating Space Efficiency of Tall Buildings in Turkey(Mdpi, 2024) Aslantamer, Ozlem Nur; Ilgin, Huseyin EmreIn response to the increasing building demands in Turkey, particularly in the metropolitan area of Istanbul, followed by other major cities such as Ankara and Izmir, the expansion of construction zones has led to the emergence of tall towers as a pragmatic solution. The design and implementation of tall buildings require newer technologies and interdisciplinary collaboration in aspects such as facade installation, vertical circulation solutions, and fire systems, compared to low-rise buildings. In spite of the proliferation of skyscrapers, there is a noticeable lack of thorough study on space efficiency in Turkey's tall buildings. This article aims to fill this significant gap in the literature. The research method employed in this study focuses on a case study of 54 modern towers constructed in Turkey between 2010 and 2023, ranging in height from 147 to 284 m. Key findings are as follows: (1) residential use, central core, and prismatic forms are the most prevalent architectural preferences; (2) the most preferred structural material and system are concrete and the shear-walled frame system, respectively; (3) average space efficiency and the percentage of core-to-gross-floor area (GFA) were 78% and 19%, respectively, with measurement ranges varying from a minimum of 64% and 9% to a maximum of 86% and 34%. This paper will provide insight for construction stakeholders, especially architects, for sound planning decisions in the development of Turkish tall buildings.Article Citation - WoS: 3Citation - Scopus: 3Integrating Personalized Thermal Comfort Devices for Energy-Efficient and Occupant-Centric Buildings(Mdpi, 2025) Turhan, Cihan; Carpino, CristinaPersonalized thermal comfort (PTC) systems aim to satisfy the individual thermal preferences of occupants rather than relying on average comfort indices. With the growing emphasis on sustainability and reducing energy consumption in buildings, energy efficiency has become a critical factor in the design and selection of PTC systems. While the development of PTC tools has accelerated in the last decade, selecting the most appropriate system remains a challenge due to the dynamic, uncertain, and multi-dimensional nature of the decision-making process. This study introduces a novel application of the KEMIRA-M multi-criteria decision-making (MCDM) method to identify the optimal PTC system for university office buildings-an area with limited prior investigation. A case study is conducted in a naturally ventilated office space located in a temperate climate zone. Eight distinct PTC alternatives are evaluated, including data-driven HVAC systems, wearable devices, and localized conditioning units. Six key criteria are considered: estimated energy consumption, capital cost, indoor and outdoor space requirements, system complexity, mobility, and energy efficiency. The results indicate that wearable wristbands, which condition the occupant's carpus area, offer the most balanced performance across criteria, while radiant ceiling/floor systems perform the poorest. Energy efficiency plays a crucial role in this evaluation, as it directly impacts both the operational cost and the environmental footprint of the system. The study's findings provide a structured and adaptable framework for HVAC engineers and designers to integrate PTC systems into occupant-centric and energy-efficient building designs.
