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Article Citation - Scopus: 1Thermodynamic Modeling and Multi-Objective Optimization of a New System Presented for Reutilization of the Lost Heat in Combined-Cycle Power Plants(John Wiley and Sons Inc, 2023) Peng,W.; Karimi Sadaghiani,O.In combined-cycle power plants, a large amount of thermal energy is lost when the boiler and steam unit are out of order and the gas unit is operated in single mode. For the first time, this work suggests every combined-cycle power plants should be equipped with this kind of energy system to recover the waste heat by producing hydrogen and generating electricity. This system combines a Rankine cycle with a thermoelectric generator, a finned-tube heat exchanger, and a proton exchange membrane to produce hydrogen. Having been designed, the suggested energy system is assessed by energy, exergy, and exergo-economy laws. Furthermore, the impacts of some effective factors on the efficiency and the costs are precisely analyzed. Eventually, the presented system is optimized considering two main purposes of exergy efficiency and costs. The achieved results show that the proposed system can effectively link to the gas unit to restore and even save the lost thermal energy in the single-mode condition. The conducted optimization attenuates the objective parameter of exergy efficiency from 48.39% to 41.65% and diminishes the costs from 550.14 to 480.82 $ GJ−1. Eventually, the optimization causes (Formula presented.) to rise from 1.2 to 1.32 kg h−1. © 2023 The Authors. Energy Technology published by Wiley-VCH GmbH.Article Selection of DNA Aptamers Against Parathyroid Hormone for Electrochemical Impedimetric Biosensor System Development(John Wiley and Sons Inc, 2025) Didarian, Reza; Bargh, Saharnaz; Gulerman, Almina; Ozalp, Veli Cengiz; Erel, Ozcan; Yildirim-Tirgil, NimetThis work presents the pioneering development of an aptamer-based electrochemical biosensor for real-time monitoring of parathyroid hormone (PTH) levels, with a focus on intraoperative assessment during parathyroid surgery. It introduces, for the first time, the selection and characterization of aptamers targeting distinct segments of the PTH peptide. The study demonstrates the feasibility and efficacy of the biosensing platform through a precisely designed experimental framework, including SELEX-based aptamer selection, aptamer-peptide interaction analysis, and biosensor fabrication. The SELEX process yields aptamers with notable binding affinities to different fragments of PTH, with the PTH (53-84) aptamer showing particularly sensitive binding to the hormone's C terminus, allowing for precise PTH analysis. Electrochemical characterization reveals significant changes in electrochemical impedance spectroscopy (EIS) signals upon exposure to varying PTH concentrations, highlighting the sensor's sensitivity and selectivity. The increase in charge transfer resistance (Rct) values with rising PTH concentrations underscores the biosensor's capability to detect PTH-induced structural changes, validating its potential for accurate measurement. The biosensor shows remarkable selectivity in the presence of common interferents in serum samples, ensuring precise PTH detection. Stability assessments over a 45-day storage period demonstrate the biosensor's robustness and long-term reliability, affirming its practical suitability. In summary, the developed aptamer-based biosensor represents a promising tool for sensitive and selective PTH detection, with potential applications in biomedical research and clinical diagnostics, particularly for intraoperative PTH analysis during parathyroidectomy. Continued research and optimization efforts hold promise for enhancing its performance and expanding its utility in diverse healthcare settings.Article Citation - Scopus: 3Intensive Care Nurses' Knowledge and Practices Regarding Medical Device-Related Pressure Injuries: a Descriptive Cross-Sectional Study(John Wiley and Sons Inc, 2024) Kurtgöz,A.; Kızıltepe,S.K.; Keskin,H.; Sönmez,M.; Aşatır,İ.This study aims to determine the levels of knowledge and practices of intensive care nurses regarding medical device-related pressure injuries (MDRPIs). This descriptive cross-sectional study was carried out between September 2023 and February 2024, involving 143 nurses working in intensive care units across three hospitals in Türkiye. The data were collected using the demographic form and the Medical Device-related Pressure Injuries Knowledge and Practice Assessment Tool (MDPI-ASSET). Of the nurses, 74.1% have encountered MDRPIs in their unit, 63.6% feel that their knowledge about MDRPIs is insufficient and 90.2% express a desire to receive training about MDRPIs. The participants' total mean MDPI-ASSET score was 11.12 (out of 21). The nurses achieved the highest mean score on the Aetiology/risk factors sub-scale and the lowest mean score on the Staging sub-scale. The analysis revealed significant differences in the mean MDPI-ASSET total scores among nurses based on the status of previous encounters with MDRPIs (t = 2.342; p = 0.021) and their feelings of responsibility for the development of MDRPIs (t = −2.746; p = 0.007). In this study, the knowledge and practices of intensive care nurses regarding medical device-induced pressure injuries were found to be inadequate. Given the frequent occurrence of MDRPIs in intensive care units, it is necessary to support nurses with continuous organizational-level training to improve the quality of care for critically ill patients. © 2024 The Author(s). International Wound Journal published by Medicalhelplines.com Inc and John Wiley & Sons Ltd.Article Dual Zn/Zr Hybrid Framework-Integrated Membranes With Enhanced Proton Conductivity and Durability for High-Temperature PEM Fuel Cells(John Wiley and Sons Inc, 2025) Altınışık, H.; Devrim, Y.This study proposes an innovative strategy for fabricating advanced composite membranes based on a poly[2,2′-(m-phenylene)-5,5′-bibenzimidazole] (PBI) matrix for high-temperature proton exchange membrane fuel cells (HT-PEMFCs). A co-synthesized hybrid porous framework incorporating both Zn- and Zr-based nanostructures was integrated into the PBI backbone, ensuring uniform dispersion and strong interfacial bonding, as verified by comprehensive structural and morphological characterizations. This dual-framework architecture promoted the formation of continuous proton-conductive channels and enhanced membrane stability under demanding operating conditions. Furthermore, the membranes were utilized after acid doping, and the hybrid structure effectively mitigated the acid leaching issue, ensuring stable long-term proton conductivity. At 0.6 V and 170°C, the membranes achieved a current density of ≈630 mA/cm2, demonstrating the critical role of structural optimization in improving fuel cell efficiency. These findings offer valuable insights into designing scalable, durable, and thermally stable membranes for next-generation HT-PEMFC applications. © 2025 Society of Plastics Engineers.
