WoS

Permanent URI for this collectionhttps://hdl.handle.net/20.500.14411/18

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Citation - WoS: 1
Acting Locally: Local Environmental Mobilizations and Campaigns
(Sage Publications Ltd, 2013) Ozen, Hayriye; Department of Public Administration and Political Science; 17. Graduate School of Social Sciences; 01. Atılım University
[No Abstract Available]
An Adaptive Element Division Algorithm for Accurate Evaluation of Singular and Near Singular Integrals in 3d
(Tubitak Scientific & Technological Research Council Turkey, 2021) Bayindir, Hakan; Baranoglu, Besim; Yazici, Ali; Software Engineering; Manufacturing Engineering; 06. School Of Engineering; 01. Atılım University
An adaptive algorithm for evaluation of singular and near singular integrals in 3D is presented. The algorithm is based on successive adaptive/selective subdivisions of the element until a prescribed error criteria is met. For evaluating the integrals in each subdivision, Gauss quadrature is applied. The method is computationally simple, memory efficient and can be applied for both triangular and quadrilateral elements, including the elements with nonplanar and/or curved surfaces. To assess the method, several examples are discussed. It has shown that the algorithm performs well for singular and near-singular integral examples presented in the paper and evaluates the integrals with very high accuracy.
Citation - Scopus: 1
Adaptive Neuro-Fuzzy Inference Technique for Estimation of Light Penetration in Reservoirs
(Springer Japan Kk, 2007) Soyupak, Selcuk; Karaer, Feza; Senturk, Engin; Hekim, Huseyin; 01. Atılım University
An adaptive neuro-fuzzy inference technique has been adopted to estimate light levels in a reservoir. The data were collected randomly from Doganci Dam Reservoir over a number of years. The input data set is a matrix with vectors of time, depth, sampling location, and incident solar radiation. The output data set is a vector representing light measured at various depths. Randomization and logarithmic transformations have been applied as preprocessing. One-half of the data have been utilized for training; testing and validation steps utilized one-fourth each. An adaptive neuro-fuzzy inference system (ANFIS) has been built as a prediction model for light penetration. Very high correlation values between predictions and real values on light measurements with relatively low root mean square error values have been obtained for training, test, and validation data sets. Elimination of the overtraining problem was ensured by satisfying close root mean square error values for all sets.
Afthd: Bayesian Accelerated Failure Time Model for High-Dimensional Time-To Data
(Springernature, 2025) Kumari, Pragya; Bhattacharjee, Atanu; Vishwakarma, Gajendra K.; Tank, Fatih; 01. Atılım University
Analyzing high-dimensional (HD) data with time-to-event outcomes poses a formidable challenge. The accelerated failure time (AFT) model, an alternative to the Cox proportional hazard model in survival analysis, lacks sufficient R packages for HD time-to-event data under the Bayesian paradigm. To address this gap, we develop the R package afthd. This tool facilitates advanced AFT modeling, offering Bayesian analysis for univariate and multivariable scenarios. This work includes diagnostic plots and an open-source R code for working with HD data, extending the conventional AFT model to the Bayesian framework of log-normal, Weibull, and log-logistic AFT models. The methodology is rigorously validated through simulation techniques, yielding consistent results across parametric AFT models. The application part is also performed on two different real HD liver cancer datasets, which reveals the proposed method's significance by obtaining inferences for survival estimates for the disease. Our developed package afthd is competent in working with HD time-to-event data using the conventional AFT model along with the Bayesian paradigm. Other aspects, like missing values in covariates within HD data and competing risk analysis, are also covered in this article.
Citation - WoS: 12
Citation - Scopus: 15
Alternative Numerical Modeling of a Superconducting Charge Qubit as an Eigenvalue Problem
(Emerald Group Publishing Ltd, 2011) Canturk, Mehmet; Kurt, Erol; Askerzade, Iman N.; Computer Engineering; 06. School Of Engineering; 01. Atılım University
Purpose - The purpose of this paper is to employ an alternative numerical approach to analyze the characteristics of superconducting charge qubit based on a single Cooper pair box (SCB), also to study the influence of the bias current. Design/methodology/approach - The paper starts with the circuit model of a charge qubit system based on Josephson junction using Hamiltonian formalism. Corresponding Schrodinger eigenvalue problem with periodic boundary condition is converted to the Mathieu type eigenvalue problem. By applying finite difference technique, energy spectrum of charge qubit is obtained and the solutions in the lowest band are obtained in the form of Bloch waves whose superposition provides a wave packet to investigate the effect of bias current to the Coulomb blockade. Findings - The paper identifies a periodic tridiagonal Hermitian matrix form of the eigenvalue problem that is believed to be a special eigenvalue problem. The paper emphasizes that Schrodinger formalism is very, useful to model superconducting qubits systems. The investigations indicate that the bias current strongly influences the Coulomb blockade and expectation value of supercurrent (as well as number of Cooper pairs) are affected by gate voltage and energy scale. Research limitations/implications - In the present study, Schrodinger eigenvalue problem is time independent, therefore, current-voltage characteristics of the charge qubit system could not be considered. The solution technique applied here can also be used to apply other type of Josephson junction based qubits and circuits. Practical implications - The paper includes theoretical findings for the development of superconducting qubit that can be valuable for experimentalist. The result obtained in this study is useful for the comparison of experimental study with the expectation value of number of Cooper pairs as function of gate voltage. Working parameters of a SCB can be determined from the findings. Originality/value This paper fulfils the contribution of the numerical study of Schrodinger equation for the investigation of superconducting qubits under the influence of bias current.
Citation - WoS: 45
Citation - Scopus: 45
An Ambipolar Low Band Gap Material Based on Bodipy and Edot
(Elsevier Science Bv, 2009) Algi, Fatih; Cihaner, Atilla; Chemical Engineering; 06. School Of Engineering; 01. Atılım University
A novel donor-acceptor type conducting polymer based on BODIPY dye as acceptor and EDOT units as donor parts is synthesized electrochemically. The unique combination of BODIPY and EDOT units provides an ambipolar (n- and p-doping processes) low band gap material (4). This is the first example of p-n junction in an organic pi-conjugated material where BODIPY unit is incorporated directly in the main chain. Furthermore, the polymer film exhibits electrochromic behavior upon p-doping: a color change from light violet (neutral) to indigo (oxidized). (C) 2009 Elsevier B.V. All rights reserved.
Citation - WoS: 33
Citation - Scopus: 34
An ambipolar neutral state green polymeric electrochromic
(Elsevier, 2009) Algi, Fatih; Cihaner, Atilla; Chemical Engineering; 06. School Of Engineering; 01. Atılım University
The synthesis and properties of highly stable neutral state green polymeric electrochromic, P1, which is based on 5,8-bis(2,3-dihydrothieno[3,4-b][1,4]dioxin-5-yl)-2,3-di(1H-pyrrol-2-yl)quinoxaline were highlighted. P1 exhibits three well-defined absorption bands with a narrow band gap (1.17 eV). The n- and p-doping (ambipolar) processes suggest that P1 is one of the most promising neutral state green polymers and it can be used in supercapacitors as either cathode or anode electrode material. Apart from the stability and the robustness of the polymer film, P1 shows multi-electrochromic behavior; gray-purple in the reduced form and highly transmissive blue color in the oxidized state. (C) 2009 Elsevier B.V. All rights reserved.
Citation - WoS: 29
Amine-Functionalized Graphene Nanosheet-Supported Pdauni Alloy Nanoparticles: Efficient Nanocatalyst for Formic Acid Dehydrogenation
(Royal Soc Chemistry, 2018) Bulut, Ahmet; Yurderi, Mehmet; Kaya, Murat; Aydemir, Murat; Baysal, Akin; Durap, Feyyaz; Zahmakiran, Mehmet; Chemical Engineering; 06. School Of Engineering; 01. Atılım University
Formic acid (HCOOH), a major by-product of biomass processing with high energy density, stability and non-toxicity, has a great potential as a safe and a convenient liquid hydrogen (H-2) storage material for combustion engines and fuel cell applications. However, high-purity hydrogen release from the catalytic decomposition of aqueous formic acid solution at desirable rates under mild conditions stands as a major challenge that needs to be solved for the practical use of formic acid in on-demand hydrogen generation systems. Described herein is a new nanocatalyst system comprised of 3-aminopropyltriethoxysilane-functionalized graphene nanosheet-supported PdAuNi alloy nanoparticles (PdAuNi/f-GNS), which can reproducibly be prepared by following double solvent method combined with liquid-phase chemical reduction, all at room temperature. PdAuNi/f-GNS selectively catalyzes the decomposition of aqueous formic acid through the dehydrogenation pathway (similar to 100% H-2 selectivity), in the absence of any promoting additives (alkali formates, Bronsted bases, Lewis bases, etc.). PdAuNi/f-GNS nanocatalyst provides CO-free H-2 generation with a turnover frequency of 1090 mol H-2 mol metal(-1) h(-1) in the additive-free dehydrogenation of formic acid at almost complete conversion (>= 92%) even at room temperature. The catalytic activity provided by PdAuNi/f-GNS nanocatalyst is higher than those obtained with the heterogeneous catalysts reported to date for the additive-free dehydrogenation of formic acid. Moreover, PdAuNi/f-GNS nanoparticles show high durability against sintering, clumping and leaching throughout the catalytic runs, so that the PdAuNi/f-GNS nanocatalyst retains almost its inherent catalytic activity and selectivity at the end of the 10th recycle.
Citation - WoS: 17
Citation - Scopus: 30
Analysis of Cultural and Gender Influences on Teamwork Performance for Software Requirements Analysis in Multinational Environments
(Wiley, 2012) Fernandez-Sanz, L.; Misra, Sanjay; Computer Engineering; 06. School Of Engineering; 01. Atılım University
Software development is mainly a social activity where teams of developers should work as a coordinated unit to fulfill the needs of customers. Studies have shown the importance of teamwork ability as the main skill for software professionals both in local settings and in global software development. Teamwork performance can be evaluated according to different approaches but we need deeper analysis within software teams of differences in individuals' performance related to culture, nationality or even gender. We applied a simple evaluation experience named teamwork benefits awareness (TBA) to groups of last-year students of computing degrees with experience as junior IT professionals during intensive multinational workshops based on international software projects. TBA allowed to measure individual and team performance during a requirements analysis session based on a real project. Results segmented by nationality and gender are presented and analysed in comparison with the data collected from computing professionals in local settings. In general, no significant differences have been found out although interesting relations are suggested with two Hofstede's country indicators. TBA is also perceived as a good technique for highlighting both teamwork benefits as well as the nature of real situations of software requirements analysis and orientation to customer needs.
Citation - WoS: 7
Citation - Scopus: 9
Analysis of the Hall Effect in Tlgate₂ Single Crystals
(Iop Publishing Ltd, 2009) Qasrawi, A. F.; Gasanly, N. M.; Department of Electrical & Electronics Engineering; 15. Graduate School of Natural and Applied Sciences; 01. Atılım University
The electrical resistivity and Hall coefficient of p-type TlGaTe2 crystals were measured in the temperature range of 110-320 K. The electrical resistivity, charge carrier density and Hall mobility data for the crystals have been analyzed by means of existing theories and models to determine the extrinsic energy levels, the carrier effective mass, the donor and acceptor concentrations and the dominant scattering mechanism in the crystal as well. The analysis of the temperature-dependent electrical resistivity recorded parallel and perpendicular to the crystal's axis ( c-axis) reflected the existence of energy levels located at 0.26 and at 0.20 eV, respectively. The difference of these two energy levels is due to crystal anisotropy. The energy level at 0.26 eV was found to represent an acceptor level, as confirmed from Hall data analysis. The temperature dependence of the carrier density was analyzed by using the single-donor-single-acceptor model. The latter analysis revealed the carrier effective mass and the acceptor and donor concentrations as 0.73m(0), 4.10 x 10(17) cm(-3) and 1.20 x 10(17) cm(-3), respectively. The Hall mobility of TlGaTe2 is found to be limited by the scattering of hole-acoustic phonon interactions. The calculated theoretical mobility fits to the experimental one under the condition that the acoustic deformation potential is 11.0 eV, which is the energy position of the top of valence band maximum that is formed by the Te 5s states.
Analyzing Space Efficiency in Japanese Tall Buildings
(Taylor & Francis Ltd, 2025) Ilgin, Huseyin Emre; Aslantamer, Ozlem Nur; Interior Architecture and Environmental Design; 03. School of Fine Arts Design & Architecture; 01. Atılım University
Space efficiency in Japanese tall buildings holds substantial significance, shaped by financial, societal, and environmental imperatives. Nevertheless, comprehensive studies addressing spatial efficiency in such towers remain scarce. To bridge this gap, this article undertakes a quantitative spatial analysis of 40 Japanese tall buildings through BIM/CAD-based floor plan evaluations and comparison of net-to-gross and core-to-GFA efficiency ratios. Key findings include: (1) mixed-use and office typologies, central cores, and prismatic massing dominate contemporary Japanese high-rise design; (2) composite structures with shear-walled frame systems are prevalent; and (3) the average net-to-gross ratio is 75%, with core areas occupying 23% of total GFA. The efficiency metrics range from 64% to 85% for net-to-gross ratios, and from 13% to 34% for core-to-GFA ratios. This research offers practical insights for stakeholders - especially architects and planners - to support more efficient and sustainable high-rise design strategies in Japan.
Citation - Scopus: 1
Analyzing Students' Academic Success in Pre-requisite Course Chains: A Case Study in Turkey
(Tempus Publications, 2018) Karakaya, Murat; Eryilmaz, Meltem; Ceyhan, Ulas; Computer Engineering; Computer Engineering; 06. School Of Engineering; 01. Atılım University
There are several principles which have been accepted as approaches to successful curriculum development. In spite of the differences in the proposed sequencing of topics, all approaches basically depend on the pre-requisite chains to implement their educational approach in the curriculum development for specifying the order of the subjects. In this research, two prerequisite chains representing two different curriculum development approaches are taken into consideration in a case study. The first research question considered is whether academic success in a follow-up course is positively related to success attained in the pre-requisite course. The second one is whether or not the selected curriculum development approach for deciding the chains has a significant impact on the academic success relationships between a pre-requisite and its follow-up course. To answer these questions, course data of 441 undergraduate students who graduated from the Atilim University between Fall 2001 and Spring 2015 semesters were collected and analyzed. The results indicate that the succes levels gained in a pre-requisite and its follow-up course are corelated. Moreover, different cirriculum development methods can affect this corelation. Thus, cirriculum developers should consider appropriate approaches to improve student success for deciding chaining courses and their contents.
Citation - WoS: 5
Citation - Scopus: 6
Analyzing Two Decades of Intimate Partner Femicide-Suicides in T?rkiye*
(Elsevier Sci Ltd, 2023) Cavlak, Mehmet; Odabasi, Aysun Balseven; Mutlu, Niluefer Dilara Ar; Erbaydar, Nueket Paksoy; 01. Atılım University
Intimate partner femicide-suicide (IPF-S) is an understudied subgroup of homicide-suicide deaths. Limited research has been conducted on IPF-Ss in the Eastern Mediterranean region. This study thus aimed to evaluate the characteristics of IPF-Ss that occurred in Turkiye between 2000 and 2019. IPF-Ss (n = 226) were extracted from electronic news stories. Data on victims, perpetrators, their relationships, and incidents of murder and suicide were collected. Descriptive statistics were calculated, and logistic regression analysis, mortality rates, and proportion of IPF-S in femicide calculations were conducted, showing that 13.3% of the femicides (n = 1699) were IPF-Ss. The IPF-Ss increased in 5-year intervals and were the highest during the 2015-2019 period (62.5%). Victims were married in 48.2% of the cases and 56% were aged <35 years, while 51.3% of the perpetrators were married and 52.6% were aged >40 years. In 42.0% of the cases, the perpetrator lived with the victim. Most (79.2%) of the cases took place in urban settlements, and the perpetrators used firearms in 84.1% of femicide cases. Firearm use was the most common method in cases where IPF-S was planned (OR = 2.98), when the IPF-S method was the same (OR = 29.6), and when the perpetrator committed suicide (OR = 7.82). In addition, it was found that firearm ownership is an important risk factor for IPF-S in Turkiye. Therefore, we recommend legislation to restrict firearms, as well as new measures to prevent illegal access to weapons.
Citation - WoS: 2
Citation - Scopus: 2
Anisotropic Electrical and Dispersive Optical Parameters in Ins Layered Crystals
(Pergamon-elsevier Science Ltd, 2010) Qasrawi, A. F.; Gasanly, N. M.; Department of Electrical & Electronics Engineering; 15. Graduate School of Natural and Applied Sciences; 01. Atılım University
The anisotropy effect on the current transport mechanism and on the dispersive optical parameters of indium monosulfide crystals has been studied by means of electrical conductivity and polarized reflectance measurements along the a-axis and the b-axis, respectively. The temperature-dependent electrical conductivity analysis in the range 10-350 K for the a-axis and in the range 30-350 K for the b-axis revealed the domination of the thermionic emission of charge carriers and the domination of variable range hopping above and below 100 K, respectively. At high temperatures (T > 100 K) the conductivity anisotropy, s, decreased sharply with decreasing temperature following the law s proportional to exp(-E(s)/kT). The anisotropy activation energy, E(s), was found to be 330 and 17 meV above and below 220 K, respectively. Below 100 K, the conductivity anisotropy is invariant with temperature. in that region, the calculated hopping parameters are altered significantly by the conductivity anisotropy. The optical reflectivity analysis in the wavelength range 250-650 nm revealed a clear anisotropy effect on the dispersive optical parameters. In particular, the static refractive index, static dielectric constant, lattice dielectric constant, dispersion energy and oscillator energy exhibited values of 2.89, 8.39, 19.7, 30.02 eV and 4.06 eV, and values of 2.76, 7.64, 25.9, 22.26 eV and 3.35 eV for light polarized along the a-axis and the b-axis, respectively. (C) 2009 Elsevier Ltd. All rights reserved.
Citation - WoS: 7
Citation - Scopus: 9
Ann-Assisted Forecasting of Adsorption Efficiency To Remove Heavy Metals
(Tubitak Scientific & Technological Research Council Turkey, 2019) Buaısha, Magdi; Balku, Şaziye; Yaman, Şeniz Özalp; Energy Systems Engineering; Chemical Engineering; 06. School Of Engineering; 01. Atılım University
In wastewater treatment, scientific and practical models utilizing numerical computational techniques suchas artificial neural networks (ANNs) can significantly help to improve the process as a whole through adsorption systems.In the modeling of the adsorption efficiency for heavy metals from wastewater, some kinetic models have been used such as pseudo first-order and second-order. The present work develops an ANN model to forecast the adsorption efficiency of heavy metals such as zinc, nickel, and copper by extracting experimental data from three case studies. To do this, we apply trial-and-error to find the most ideal ANN settings, the efficiency of which is determined by mean square error (MSE) and coefficient of determination (R2). According to the results, the model can forecast adsorption efficiency percent (AE%) with a tangent sigmoid transfer function (tansig) in the hidden layer with 10 neurons and a linear transferfunction (purelin) in the output layer. Furthermore, the Levenberg–Marquardt algorithm is seen to be most ideal for training the algorithm for the case studies, with the lowest MSE and high R2 . In addition, the experimental results and the results predicted by the model with the ANN were found to be highly compatible with each other.
Ann-Based Maximum Power Tracking for a Grid-Synchronized Wind Turbine-Driven Doubly Fed Induction Generator Fed by Matrix Converter
(Multidisciplinary Digital Publishing Institute (MDPI), 2025) Alarabi, M.A.; Sünter, S.; 01. Atılım University
The integration of renewable energy sources, such as wind power, into the electrical grid is essential for the development of sustainable energy systems. Doubly fed induction generators (DFIGs) have been significantly utilized in wind energy conversion systems (WECSs) because of their efficient power generation and variable speed operation. However, optimizing wind power extraction at variable wind speeds remains a major challenge. To address this, an artificial neural network (ANN) is adopted to predict the optimal shaft speed, ensuring maximum power point tracking (MPPT) for a wind energy-driven DFIG connected to a matrix converter (MC). The DFIG is controlled via field-oriented control (FOC), which allows independent power output regulation and separately controls the stator active and reactive power components. Through its compact design, bidirectional power flow, and enhanced harmonic performance, the MC, which is controlled by the simplified Venturini modulation technique, improves the efficiency and dependability of the system. Simulation outcomes confirm that the ANN-based MPPT enhances the power extraction efficiency and improves the system performance. This study shows how wind energy systems can be optimized for smart grids by integrating advanced control techniques like FOC and simplified Venturini modulation with intelligent algorithms like ANN. © 2025 by the authors.
Citation - WoS: 6
Citation - Scopus: 6
Anodic Oxidation of N-Substituted Dipyrrolyl Linked by Polyether Bridge
(Taylor & Francis inc, 2006) Cihaner, Atilla; Chemical Engineering; 06. School Of Engineering; 01. Atılım University
Electroactive polymer containing polyether pseudo-cages has been synthesized by anodic oxidation of 1,11-bis(1,1-pyrrole)-3,6,9-trioxaundecane (I) using acetonitrile (ACN) as solvent and tetrabutylammonium perchlorate (TBAClO 4 ) as supporting electrolyte. Electrochemical behavior of monomer I and its polymer, poly-I , were studied using cyclic voltammetry (CV) and UV-VIS spectroscopic techniques. Also, a doping/dedoping study was carried out using electron spin resonance (ESR) and UV-VIS spectroscopic techniques. Thermal behavior of the product was studied using differential scanning calorimetry (DSC) and thermal gravimetric analysis (TGA).
Citation - WoS: 1
Citation - Scopus: 1
Anticipatory Effect of Execution on Observation: an Approach Using Exopinch Finger Robot
(Tubitak Scientific & Technological Research Council Turkey, 2019) Arıkan, Kutluk Bilge; Zadeh, Hassan Gol Mohammad; Turgut, Ali Emre; Zinnuroğlu, Murat; Bayer, Gözde; Günendi, Zafer; Cengiz, Bülent; Department of Mechatronics Engineering; 01. Atılım University
Background/aim: This study aims to explore the mirror neuron system (MNS) involvement using mu (8–12 Hz)/beta (15–25 Hz) bandsuppression in an action observation-execution paradigm.Materials and methods: Electrophysiological (EEG) data from 16 electrodes were recorded while 8 participants observed video clips ofa hand squeezing a spring. Specifically, the effect of anticipated execution on observation was studied. For this purpose, a fully actuatedfinger exoskeleton robot was utilized to synchronize observation and execution and to control the execution condition for the participants. Anticipatory effect was created with a randomized robot accompany session.Results: The results showed that the observational condition (with or without anticipation) interacted with hemisphere at central channels near somatosensory cortex. Additionally, we explored the response of MNS on the kinetics features of visual stimuli (hard or softspring).Conclusion: The results showed an interaction effect of kinetics features and hemisphere at frontal channels corresponding nearly tothe ventral premotor cortex area of the brain. The activation of mirror neurons in this area plays a crucial role in observational learning.Based on our results, we propose that specific type of visual stimuli can be combined with the functional abilities of the MNS in the action observation based treatment of hand motor dysfunction of stroke patients to have a positive additional impact.
Citation - WoS: 2
Citation - Scopus: 2
Antiproliferative Activity of Platinum(ii) and Copper(ii) Complexes Containing Novel Biquinoxaline Ligands
(Oxford Univ Press, 2024) El-Beshti, Hager Sadek; Gercek, Zuhal; Kayi, Hakan; Yildizhan, Yasemin; Cetin, Yuksel; Adiguzel, Zelal; Ozalp-Yaman, Seniz; Chemical Engineering; 06. School Of Engineering; 01. Atılım University
Nowadays, cancer represents one of the major causes of death in humans worldwide, which renders the quest for new and improved antineoplastic agents to become an urgent issue in the field of biomedicine and human health. The present research focuses on the synthesis of 2,3,2MODIFIER LETTER PRIME,3MODIFIER LETTER PRIME-tetra(pyridin-2-yl)-6,6MODIFIER LETTER PRIME-biquinoxaline) and (2,3,2MODIFIER LETTER PRIME,3MODIFIER LETTER PRIME-tetra(thiophen-2-yl)-6,6MODIFIER LETTER PRIME-biquinoxaline) containing copper(II) and platinum(II) compounds as prodrug candidates. The binding interaction of these compounds with calf thymus DNA (CT-DNA) and human serum albumin were assessed with UV titration, thermal decomposition, viscometric, and fluorometric methods. The thermodynamical parameters and the temperature-dependent binding constant (KMODIFIER LETTER PRIMEb) values point out to spontaneous interactions between the complexes and CT-DNA via the van der Waals interactions and/or hydrogen bonding, except Cu(ttbq)Cl2 for which electrostatic interaction was proposed. The antitumor activity of the complexes against several human glioblastomata, lung, breast, cervix, and prostate cell lines were investigated by examining cell viability, oxidative stress, apoptosis-terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling, in vitro migration and invasion, in vitro-comet DNA damage, and plasmid DNA interaction assays. The U87 and HeLa cells were investigated as the cancer cells most sensitive to our complexes. The exerted cytotoxic effect of complexes was attributed to the formation of the reactive oxygen species in vitro. It is clearly demonstrated that Cu(ttbq)Cl2, Pt(ttbq)Cl2, and Pt(tpbq)Cl2 have the highest DNA degradation potential and anticancer effect among the tested complexes by leading apoptosis. The wound healing and invasion analysis results also supported the higher anticancer activity of these two compounds. Graphical Abstract Antitumor activity of biqunoxaline complexes.
Citation - WoS: 16
Citation - Scopus: 22
Applicability of Weyuker's Properties on Oo Metrics: Some Misunderstandings
(Comsis Consortium, 2008) Misra, Sanjay; Akman, Ibrahim; Computer Engineering; 06. School Of Engineering; 01. Atılım University
Weyuker's properties have been suggested as a guiding tool in identification of a good and comprehensive complexity measure by several researchers. Weyuker proposed nine properties to evaluate complexity measure for traditional programming. However, they are extensively used for evaluating object-oriented (OO) metrics, although the object-oriented features are entirely different in nature. In this paper, two recently reported OO metrics were evaluated and, based on it; the usefulness and relevance of these properties for evaluation purpose for object-oriented systems is discussed.

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