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Article Citation - WoS: 3Citation - Scopus: 3Modeling and Measurement of Human Body Blockage Loss at 28 Ghz(Taylor & Francis Ltd, 2023) Benzaghta, Mohamed; Gokdogan, Bengisu Yalcinkaya; Coruk, Remziye Busra; Kara, AliMillimeter-wave (mm-Wave) spectrum is an essential enabler to the fifth generation (5G) wireless technology. Humans are one of the most noticeable blockers that cause temporal variation in indoor radio channels. This paper presents human blockage measurements at 28 GHz, with several humans of different sizes. The effect of the crossing orientations of the human bodies is investigated for three different transmitter heights. A human blockage model based on the Fresnel diffraction scheme is shown to be applicable in estimating the human blockage loss in indoor radio links considering various body sizes, different crossing orientations, and different transmitter heights. The findings reported in this paper could help improve indoor radio channel models at 28 GHz bands for 5G technologies considering the presence of human body blockages.Article Citation - WoS: 1Citation - Scopus: 1Machine Vs. Deep Learning Comparision for Developing an International Sign Language Translator(Taylor & Francis Ltd, 2022) Eryilmaz, Meltem; Balkaya, Ecem; Ucan, Eylul; Turan, Gizem; Oral, Seden GulayThis study aims to enable deaf and hard-of-hearing people to communicate with other individuals who know and do not know sign language. The mobile application was developed for video classification by using MediaPipe Library in the study. While doing this, considering the problems that deaf and hearing loss individuals face in Turkey and abroad modelling and training stages were carried out with the English language option. With the real-time translation feature added to the study individuals were provided with instant communication. In this way, communication problems experienced by hearing-impaired individuals will be greatly reduced. Machine learning and Deep learning concepts were investigated in the study. Model creation and training stages were carried out using VGG16, OpenCV, Pandas, Keras, and Os libraries. Due to the low success rate in the model created using VGG16, the MediaPipe library was used in the formation and training stages of the model. The reason for this is that, thanks to the solutions available in the MediaPipe library, it can normalise the coordinates in 3D by marking the regions to be detected in the human body. Being able to extract the coordinates independently of the background and body type in the videos in the dataset increases the success rate of the model in the formation and training stages. As a result of an experiment, the accuracy rate of the deep learning model is 85% and the application can be easily integrated with different languages. It is concluded that deep learning model is more accure than machine learning one and the communication problem faced by hearing-impaired individuals in many countries can be reduced easily.Article Citation - WoS: 6Effectiveness of Proprioceptive Neuromuscular Facilitation and Myofascial Release Techniques in Patients With Subacromial Impingement Syndrome(Taylor & Francis Ltd, 2022) Celik, Merve Sinem; Sonmezer, Emel; Acar, ManolyaPurpose To compare the effectiveness of proprioceptive neuromuscular facilitation and myofascial release technique in patients with subacromial impingement syndrome on pain, range of motion, muscle strength, quality of life, functionality and disability. Methods Thirty patients were randomly divided into two groups: proprioceptive neuromuscular facilitation group (n = 15) and proprioceptive neuromuscular facilitation combined with myofascial release technique group (n = 15). Both treatment methods were performed 3 times a week for 4 weeks. Pain severity was assessed by Visuel Analog Scale, range of motion by a goniometer, muscle strength by digital hand dynamometer, quality of life by Nottingham health profile, functionality by arm, shoulder and hand problems questionnaire, disability by shoulder pain and disability index. All measurements were used before and after treatments. Pain severity, range of motion and muscle strength were also evaluated after the first session. Results After the treatment, shoulder pain, range of motion, muscle strength, functionality and disability were improved in two groups (p < 0.05). Proprioceptive neuromuscular facilitation showed improvement in pain, whereas myofascial release technique improved pain, physical activity, emotional state, sleep and total dimensions of life quality (p < 0.05). Proprioceptive neuromuscular facilitation was more effective in reducing activity pain, whereas myofascial release technique was more effective in increasing flexion, external and internal rotation range of motion, flexion and abduction muscle strength after the first session (p < 0.05). Conclusions The combined application of proprioceptive neuromuscular facilitation and myofascial release technique has a more acute and cumulative positive effect on pain, range of motion, muscle strength, functionality, disability and quality of life in patients with subacromial impingement syndrome.Article Citation - WoS: 2Citation - Scopus: 2Cb65 and Novel Cb65 Liposomal System Suppress Mg63 and Saos-2 Osteosarcoma Cell Growth in Vitro(Taylor & Francis Ltd, 2024) Zorba, Basak Isil; Boyacioglu, Oezge; Caglayan, Tugba; Recber, Tuba; Nemutlu, Emirhan; Eroglu, Ipek; Korkusuz, PetekCurable approaches for primary osteosarcoma are inadequate and urge investigation of novel therapeutic formulations. Cannabinoid ligands exert antiproliferative and apoptotic effect on osteosarcoma cells via cannabinoid 2 (CB2) or transient receptor potential vanilloid type (TRPV1) receptors. In this study, we confirmed CB2 receptor expression in MG63 and Saos-2 osteosarcoma cells by qRT-PCR and flow cytometry (FCM), then reported the reduction effect of synthetic specific CB2 receptor agonist CB65 on the proliferation of osteosarcoma cells by WST-1 (water-soluble tetrazolium-1) and RTCA (real-time impedance-based proliferation). CB65 revealed an IC50 (inhibitory concentration) for MG63 and Saos-2 cells as 1.11 x 10(-11) and 4.95 x 10(-11) M, respectively. The specific antiproliferative effect of CB65 on osteosarcoma cells was inhibited by CB2 antagonist AM630. CB65 induced late apoptosis of MG63 and Saos-2 cells at 24 and 48 h, respectively by FCM when applied submaximal concentration. A novel CB65 liposomal system was generated by a thin film hydration method with optimal particle size (141.7 +/- 0.6 nm), polydispersity index (0.451 +/- 0.026), and zeta potential (-10.9 +/- 0.3 mV) values. The encapsulation efficiency (EE%) of the CB65-loaded liposomal formulation was 51.12%. The CB65 and CB65-loaded liposomal formulation releasing IC50 of CB65 reduced proliferation by RTCA and invasion by scratch assay and induced late apoptosis of MG63 and Saos-2 cells, by FCM. Our results demonstrate the CB2 receptor-mediated antiproliferative and apoptotic effect of a new liposomal CB65 delivery system on osteosarcoma cells that can be used as a targeted and intelligent tool for bone tumors to ameliorate pediatric bone cancers following in vivo validation.Article Citation - WoS: 23Citation - Scopus: 27Facile synthesis of CsPbBr3/PbSe composite clusters(Taylor & Francis Ltd, 2018) Thang Phan Nguyen; Ozturk, Abdullah; Park, Jongee; Sohn, Woonbae; Tae Hyung Lee; Jang, Ho Won; Kim, Soo YoungIn this work, CsPbBr3 and PbSe nanocomposites were synthesized to protect perovskite material from self-enlargement during reaction. UV absorption and photoluminescence (PL) spectra indicate that the addition of Se into CsPbBr3 quantum dots modified the electronic structure of CsPbBr3, increasing the band gap from 2.38 to 2.48 eV as the Cs:Se ratio increased to 1:3. Thus, the emission color of CsPbBr3 perovskite quantum dots was modified from green to blue by increasing the Se ratio in composites. According to X-ray diffraction patterns, the structure of CsPbBr3 quantum dots changed from cubic to orthorhombic due to the introduction of PbSe at the surface. Transmission electron microscopy and X-ray photoemission spectroscopy confirmed that the atomic distribution in CsPbBr3/PbSe composite clusters is uniform and the composite materials were well formed. The PL intensity of a CsPbBr3/PbSe sample with a 1:1 Cs: Se ratio maintained 50% of its initial intensity after keeping the sample for 81 h in air, while the PL intensity of CsPbBr3 reduced to 20% of its initial intensity. Therefore, it is considered that low amounts of Se could improve the stability of CsPbBr3 quantum dots.Review Citation - WoS: 18Citation - Scopus: 24A Literature Review on Mhe Selection Problem: Levels, Contexts, and Approaches(Taylor & Francis Ltd, 2015) Saputro, Thomy Eko; Masudin, Ilyas; Rouyendegh (Babek Erdebilli), Babak DaneshvarThis paper presents a review on selection problem of material handling equipment (MHE) and general equipment used in industry area. The issue on MHE is widely paid attention since MHE has contribution on material, good and product accomplishment. Few methods and softwares have been proposed and developed to select the most appropriate MHE for a complex selection problem. Today's high diverisity of MHE categories and types influence the generation of many possible choices which leads to the complexity. In this paper, a further discussion in terms of MHE and equipment including three major points namely level of selection, the context of selection problem and the approaches are served to highlight the complex MHE selection according to the number of possible choices provided, to analyse the consideration for the problem context, and to reveal the superior method for complex MHE selection. Forty-two papers collected from the past study are presented asscociating each point of the discussion.Article Mixed Method Investigation of the Major Challenges to the Sustainable Deployment of the Electric Vehicle Charging Station Network in Türkiye(Taylor & Francis Ltd, 2025) Erol, Ismail; Oztel, Ahmet; Peker, Iskender; Ar, Ilker Murat; Benli, Tolga; Turan, IsmetCharging the increasing number of electric vehicles (EVs) in use requires the deployment of EV charging station networks (EVCSN). However, there are various challenges to deploying EVCSN in a sustainable manner. T & uuml;rkiye, a developing country, should also build a robust EVCSN to encourage future adoption of EVs as the country's market for EVs has been rapidly growing. The literature review concludes that no previous study has systematically explored challenges to the sustainable deployment of EVCSN. The goal of this study is, therefore, twofold: first, it identifies those challenges through the lenses of commonly used theories. Second, it explores them using a multi-criteria decision-making (MCDM) framework that incorporates a rough-derived interval-valued neutrosophic set (R-IVN)-based ISM into MICMAC. By deriving interval neutrosophic information from single-valued expert inputs using rough number operators, the proposed approach more accurately captures epistemic uncertainty and variability in expert judgments compared to conventional interval-based models. The method is further validated through a novel Dice-S & oslash;rensen similarity index-based simulation approach. The findings of this study suggest that developing government policies and regulations and addressing the existence of vertically integrated companies are the critical challenges with higher driving powers. These findings provide key responsibilities for stakeholders, including urban municipalities, in developing guidelines for EVCSN deployment.Review Citation - WoS: 10Citation - Scopus: 10Latest Developments in Engineered Skeletal Muscle Tissues for Drug Discovery and Development(Taylor & Francis Ltd, 2023) Ostrovidov, Serge; Ramalingam, Murugan; Bae, Hojae; Orive, Gorka; Fujie, Toshinori; Shi, Xuetao; Kaji, HirokazuIntroductionWith the advances in skeletal muscle tissue engineering, new platforms have arisen with important applications in biology studies, disease modeling, and drug testing. Current developments highlight the quest for engineering skeletal muscle tissues with higher complexity . These new human skeletal muscle tissue models will be powerful tools for drug discovery and development and disease modeling.Areas coveredThe authors review the latest advances in in vitro models of engineered skeletal muscle tissues used for testing drugs with a focus on the use of four main cell culture techniques: Cell cultures in well plates, in microfluidics, in organoids, and in bioprinted constructs. Additional information is provided on the satellite cell niche.Expert opinionIn recent years, more sophisticated in vitro models of skeletal muscle tissues have been fabricated. Important developments have been made in stem cell research and in the engineering of human skeletal muscle tissue. Some platforms have already started to be used for drug testing, notably those based on the parameters of hypertrophy/atrophy and the contractibility of myotubes. More developments are expected through the use of multicellular types and multi-materials as matrices . The validation and use of these models in drug testing should now increase.Article Citation - WoS: 18Citation - Scopus: 18A New Outlier Detection Method Based on Convex Optimization: Application To Diagnosis of Parkinson's Disease(Taylor & Francis Ltd, 2021) Taylan, Pakize; Yerlikaya-Ozkurt, Fatma; Bilgic Ucak, Burcu; Weber, Gerhard-WilhelmNeuroscience is a combination of different scientific disciplines which investigate the nervous system for understanding of the biological basis. Recently, applications to the diagnosis of neurodegenerative diseases like Parkinson's disease have become very promising by considering different statistical regression models. However, well-known statistical regression models may give misleading results for the diagnosis of the neurodegenerative diseases when experimental data contain outlier observations that lie an abnormal distance from the other observation. The main achievements of this study consist of a novel mathematics-supported approach beside statistical regression models to identify and treat the outlier observations without direct elimination for a great and emerging challenge in humankind, such as neurodegenerative diseases. By this approach, a new method named as CMTMSOM is proposed with the contributions of the powerful convex and continuous optimization techniques referred to as conic quadratic programing. This method, based on the mean-shift outlier regression model, is developed by combining robustness of M-estimation and stability of Tikhonov regularization. We apply our method and other parametric models on Parkinson telemonitoring dataset which is a real-world dataset in Neuroscience. Then, we compare these methods by using well-known method-free performance measures. The results indicate that the CMTMSOM method performs better than current parametric models.Article Citation - WoS: 2Citation - Scopus: 2Influence of Surface Finish on Flexural Strength and Microhardness of Indirect Resin Composites and the Effect of Thermal Cycling(Taylor & Francis Ltd, 2012) Bicer, Arzu Zeynep Yildirim; Dogan, Arife; Dogan, Orhan Murat; Sengonul, Merih Cemal; Artvin, ZaferThis study investigated the effect of surface finish and thermal cycling procedures on flexural strength and surface microhardness of three indirect resin composites, Artglass (R), Signum (R), and Solidex (R). The specimens were prepared in sufficient number and size according to flexural and microhardness test requirements (n=10). Scanning electron microscopy-energy dispersive x-ray (SEM-EDX) analysis was also used for studying the morphology, dispersion, and elemental compositions of fillers. The EDX results showed that Artglass contained 1.57% aluminium oxide (Al2O3), 53.29% silicon dioxide (SiO2), and 2.62% barium oxide (BaO); Signum had 55.69% silicon dioxide (SiO2) and Solidex had 44.99% silicon dioxide (SiO2) of total mass. Artglass appeared to display the best flexural strength values under all the test conditions employed (range: 116.8 +/- 32.18 to 147.8 +/- 47.97 MPa), and it was followed by Signum (range: 93.7 +/- 22.84 to 118.0 +/- 33.45 MPa). Thermal cycling did not seem to have affected the flexural strength of Artglass and Signum (p > 0.05); however, it led to a significant decrease, from (110.5 +/- 20.69 MPa) to 74.0 +/- 13.30 MPa (p < 0.001), in the strength of polished Solidex specimens. While surface microhardness of the three materials increased by polishing ( Artglass: 55.7 +/- 2.64/74.1 +/- 8.63 Vickers Hardness Numbers (VHN); Signum: 44.8 +/- 3.12/60.7 +/- 4.50 VHN; Solidex: 44.0 +/- 2.31/53.4 +/- 3.58 VHN for unpolished/polpolished specimens), thermal cycling had a deleterious effect on this property (p < 0.001).
