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Article Citation - WoS: 121Citation - Scopus: 134Isrm Suggested Methods for Determining the Creep Characteristics of Rock(Springer Wien, 2014) Aydan, Oemer; Ito, Takashi; Oezbay, Ugur; Kwasniewski, M.; Shariar, K.; Okuno, T.; Okada, T.[No Abstract Available]Article Citation - WoS: 29Citation - Scopus: 38An Experimental Study of Cutting Performances of Worn Picks(Springer Wien, 2016) Dogruoz, Cihan; Bolukbasi, Naci; Rostami, Jamal; Acar, CemilThe best means to assess rock cuttability and efficiency of cutting process for using mechanical excavation is specific energy (SE), measured in full-scale rock cutting test. This is especially true for the application of roadheaders, often fitted with drag-type cutting tools. Radial picks or drag bits are changed during the operation as they reach a certain amount of wear and become blunt. In this study, full-scale cutting tests in different sedimentary rock types with bits having various degree of wear were used to evaluate the influence of bit wear on cutting forces and specific energy. The relationship between the amount of wear as represented by the size of the wear flats at the tip of the bit, and cutting forces as well as specific energy was examined. The influence of various rock properties such as mineral content, uniaxial compressive strength, tensile strength, indentation index, shore hardness, Schmidt hammer hardness, and density with required SE of cutting using different levels of tool wear was also studied. The preliminary analysis of the data shows that the mean cutting forces increase 2-3 times and SE by 4-5 times when cutting with 4 mm wear flat as compared to cutting with new or sharp wedge shape bits. The grain size distribution of the muck for cutting different rock types and different level of bit wear was analyzed and discussed. The best fit prediction models for SE based on statistical analysis of laboratory test results are introduced. The model can be used for estimating the performance of mechanical excavators using radial tools, especially roadheaders, continuous miners and longwall drum shearers.Article Citation - WoS: 22Citation - Scopus: 27The Stress Response and Onset of Yield of Rotating Fgm Hollow Shafts(Springer Wien, 2006) Akis, T.; Eraslan, A. N.An analytical model is developed to study the stress response and the yielding of rotating functionally graded hollow shafts in the framework of generalized plane strain. The modulus of elasticity and the uniaxial yield limit of the shaft material are assumed to vary radially in nonlinear forms. It is shown that different modes of plasticization may take place. Analytical expressions for the critical values of the material parameters leading to different modes of plastic deformation and the corresponding elastic limit rotation speeds are derived by the use of Tresca's yield criterion.Article Citation - WoS: 10Citation - Scopus: 11Biosensor for Atp Detection Via Aptamer-Modified Pda@poss Nanoparticles Synthesized in a Microfluidic Reactor(Springer Wien, 2024) Kibar, Gunes; Sahinoglu, O. Berkay; Kilincli, Betul; Erdem, E. Yegan; Cetin, Barbaros; Ozalp, V. CengizThis study introduces aptamer-functionalized polyhedral oligomeric silsesquioxane (POSS) nanoparticles for adenosine triphosphate (ATP) detection where the POSS nanoparticles were synthesized in a one-step, continuous flow microfluidic reactor utilizing thermal polymerization. A microemulsion containing POSS monomers was generated in the microfluidic reactor which was designed to prevent clogging by using a continuous oil flow around the emulsion during thermal polymerization. Surfaces of POSS nanoparticles were biomimetically modified by polydopamine. The aptamer sequence for ATP was successfully attached to POSS nanoparticles. The aptamer-modified POSS nanoparticles were tested for affinity-based biosensor applications using ATP as a model molecule. The nanoparticles were able to capture ATP molecules successfully with an affinity constant of 46.5 mu\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\upmu $$\end{document}M. Based on this result, it was shown, for the first time, that microfluidic synthesis of POSS nanoparticles can be utilized in designing aptamer-functionalized nanosystems for biosensor applications. The integration of POSS in biosensing technologies not only exemplifies the versatility and efficacy of these nanoparticles but also marks a significant contribution to the field of biorecognition and sample preparation.Article Citation - WoS: 5Citation - Scopus: 5Aptamer decorated PDA@magnetic silica microparticles for bacteria purification(Springer Wien, 2024) Kavruk, Murat; Babaie, Zahra; Kibar, Gunes; Cetin, Barbaros; Yesilkaya, Hasan; Amrani, Yassine; Ozalp, V. CengizOne significant constraint in the advancement of biosensors is the signal-to-noise ratio, which is adversely affected by the presence of interfering factors such as blood in the sample matrix. In the present investigation, a specific aptamer binding was chosen for its affinity, while exhibiting no binding affinity towards non-target bacterial cells. This selective binding property was leveraged to facilitate the production of magnetic microparticles decorated with aptamers. A novel assay was developed to effectively isolate S. pneumoniae from PBS or directly from blood samples using an aptamer with an affinity constant of 72.8 nM. The capture experiments demonstrated efficiencies up to 87% and 66% are achievable for isolating spiked S. pneumoniae in 1 mL PBS and blood samples, respectively.Article Citation - WoS: 16Citation - Scopus: 16Elastic Analysis of Variable Profile and Polar Orthotropic Fgm Rotating Disks for a Variation Function With Three Parameters(Springer Wien, 2017) Essa, Saad; Argeso, HakanAnalytical solutions are developed for the analysis of elastic polar orthotropic functionally graded annular disks rotating with constant angular velocity. The formulations are carried out by presuming a state of plane stress and small deformations. The elasticity moduli and thickness are varied radially by a nonlinear function controlled by three parameters, while the radial variation of density may be defined by any form of continuous function. Poisson's ratios are taken to be constant. Annular disks having traction-free inner and outer surfaces, and annular disks mounted on a circular rigid shaft having traction-free outer surface are studied separately. The analytical solutions are verified numerically by the use of a computational model based on the nonlinear shooting method. An analysis that inspects the effects of the degree of orthotropy is presented. Elastic limit angular velocities are determined according to Hosford's yield criteria. Stress, displacement and strain profiles are compared within the elastic range.Article Citation - WoS: 18Citation - Scopus: 20Quartz Crystal Microbalance-Based Aptasensor Integrated With Magnetic Pre-Concentration System for Detection of listeria Monocytogenes in Food Samples(Springer Wien, 2024) Beyazit, Fatma; Arica, Mehmet Yakup; Acikgoz-Erkaya, Ilkay; Ozalp, Veli Cengiz; Bayramoglu, GulayA fast and accurate identification of Listeria monocytogenes. A new quartz crystal microbalance (QCM) aptasensor was designed for the specific and rapid detection of L. monocytogenes. Before detection of the target bacterium from samples in the QCM aptasensor, a magnetic pre-enrichment system was used to eliminate any contaminant in the samples. The prepared magnetic system was characterized using ATR-FTIR, SEM, VSM, BET, and analytical methods. The saturation magnetization values of the Fe3O4, Fe3O4@PDA, and Fe3O4@PDA@DAPEG particles were 57.2, 40.8, and 36.4 emu/g, respectively. The same aptamer was also immobilized on the QCM crystal integrated into QCM flow cell and utilized to quantitatively detect L. monocytogenes cells from the samples. It was found that a specific aptamer-magnetic pre-concentration system efficiently captured L. monocytogenes cells in a short time (approximately 10 min). The Fe3O4@PDA@DA-PEG-Apt particles provided selective isolation of L. monocytogenes from the bacteria-spiked media up to 91.8%. The immobilized aptamer content of the magnetic particles was 5834 mu g/g using 500 ng Apt/mL. The QCM aptasensor showed a very high range of analytical performance to the target bacterium from 1.0 x 10(2) and 1.0 x 10(7) CFU/mL. The limit of detection (LOD) and limit of quantitation (LOQ) were 148 and 448 CFU/mL, respectively, from the feeding of the QCM aptasensor flow cell with the eluent of the magnetic pre-concentration system. The reproducibility of the aptasensor was more than 95%. The aptasensor was very specific to L. monocytogenes compared to the other Listeria species (i.e., L. ivanovii, L. innocua, and L. seeligeri) or other tested bacteria such as Staphylococcus aureus, Escherichia coli, and Bacillus subtilis. The QCM aptasensor was regenerated with NaOH solution, and the system was reused many times.Article Citation - WoS: 93Citation - Scopus: 101On the Plane Strain and Plane Stress Solutions of Functionally Graded Rotating Solid Shaft and Solid Disk Problems(Springer Wien, 2006) Eraslan, AN; Akış, Tolga; Akis, T; Akış, Tolga; Civil Engineering; Civil EngineeringClosed form solutions to functionally graded rotating solid shaft and rotating solid disk problems are obtained under generalized plane strain and plane stress assumptions, respectively. The nonhomogeneity in the material arises from the fact that the modulus of elasticity of the material varies radially according to two different continuously nonlinear forms: exponential and parabolic. Both forms contain two material parameters and lead to finite values of the modulus of elasticity at the center. Analytical expressions for the stresses at the center are determined. These limiting expressions indicate that at the center of shaft/disk: (i) the stresses are finite, (ii) the radial and the circumferential stress components are equal, and (iii) the values of the stresses are independent of the variation of the modulus of elasticity. It is also shown mathematically that the nonhomogeneous solutions presented here reduce to those of homogeneous ones by an appropriate choice of the material parameters describing the variation of the modulus of elasticity.Article Citation - WoS: 18Citation - Scopus: 20Periodicity in Precipitation and Temperature for Monthly Data of Turkey(Springer Wien, 2021) Akdi, Yilmaz; Unlu, Kamil DemirberkIn this study, we model and forecast monthly average temperature and monthly average precipitation of Turkey by employing periodogram-based time series methodology. We compare autoregressive integrated moving average methodology and harmonic regression. We show that harmonic regression performs better than the classical methodology in both time series. Also, we find that the monthly average temperature and monthly average precipitation have two different periodic structures of 6 months and 12 months which coincide with the seasonal pattern of the time series.
