99 results
Search Results
Now showing 1 - 10 of 99
Article Citation - WoS: 1Citation - Scopus: 1Short-Term Effectiveness of Epidermis Dermis Fascia Kinesiotaping Technique in Myofascial Pain Syndrome on Upper Trapezius: a Multi-Center, Double-Blind, Randomized Clinical Study(Baycinar Medical Publ-Baycinar Tibbi Yayincilik, 2024) Ayhan, Fikriye Figen; Külcü, Duygu Geler; Keleş, Elif Çiğdem; Dinç, Arzu; Mesci, Nilgün; Çakmak, Bahar; Yılmaz, Zeynep Alpoğuz; Erhan, Belgin; Yavas, Arzu Ding; Kölcö, Duygu Geler; Tur, Birkan SonelObjectives: This study aims to investigate the efficacy of epidermis dermis fascia (EDF) kinesiotaping (KT) technique on pain intensity, number of active trigger points (TrPs), cervical range of motion (ROM) angles, and disability levels in patients with myofascial pain syndrome (MPS) on upper trapezius (UT) muscle. Patients and methods: Between January 2019 and January 2020, a total of 180 patients (21 males, 159 females; mean age: 35.9±9.0 years; range, 18 to 56 years) with MPS were included. The patients were randomized into either KT with EDF technique (Group 1) or sham KT (Group 2). Outcome measures were Visual Analog Scale (VAS) pain score, number of active TrPs, cervical ROM angles, and Neck Pain Disability Scale (NPDS). Results: Both groups improved in terms of all outcome parameters except for cervical flexion and extension angles in Group 2. The VAS pain scores significantly decreased in Group 1 (p<0.05), compared to Group 2. The number of active TrPs (p=0.001) and NPDS scores (p=0.016) of Group 1 significantly improved than Group 2. Cervical flexion (p=0.001), extension (p=0.001), and left and right lateral flexion angles (p<0.0001) significantly improved in Group 1. Cervical left (p=0.001) and right (p<0.0001) lateral flexion angles significantly improved in Group 2. There was no significant difference between the groups regarding cervical ROM angles. Conclusion: Our study results suggest that KT with the EDF technique is an effective method in reducing pain and number of active TrPs, improving disability and cervical ROM angles.Article Citation - WoS: 13Citation - Scopus: 13Evaluation of procedural and clinical outcomes of transcatheter aortic valve implantation: A single-center experience(Kare Publ, 2020) Karaduman, Bilge Duran; Kayaoğlu, Hüseyin Ayhan; Keleş, Telat; Bozkurt, Engin; Ayhan, HuseyinObjective: Transcatheter aortic valve implantation (TAVI) is an established alternative to surgical aortic valve replacement. Our study aimed to evaluate the implementation of TAVI at our large-volume center, having an all-comer patient population with short and long-term follow-ups. Methods: This retrospective, single-center analysis included 556 consecutive patients with symptomatic severe aortic stenosis (AS) who underwent TAVI between July 2011 and December 2019. Results: The mean age of the entire population was 77.6±7.9 years, and 54.9% were women. The Society of Thoracic Surgeons (STS) mean score of the cohort was 6.0%±3.5%. The balloon-expandable valve (Sapien XT, Sapien 3; Edwards Lifesciences, Irvine, California) was the most frequently used valves in this cohort (94.6%). Transfemoral access was used in 96.3% of patients. Implantation success was achieved in 96.6% of cases. During the TAVI procedure, 7.2% of patients required permanent pacemaker implantation, with 37.5% in the Lotus valve group needing the most permanent pacemakers. The mean length of hospital stay for the entire cohort was 4.5±2.3 days. Overall, 22 (3.9%) in-hospital deaths occurred before hospital discharge. The mean follow-up period was 15.1±14.9 months for all patients, and a significant improvement was noted in all echocardiographic parameters and functional capacity. Paravalvular leak (PVL) was documented in 18.9% patients, mild in 17.9%, and moderate in 1% at discharge. No cases with severe PVL, necessitating additional procedures. The multiple logistic regression analysis revealed that sex, STS score, baseline SYNTAX score, bicuspid valve morphology, common femoral artery diameter, and post-TAVI PVL were independent predictors of overall mortality. Conclusion: To our knowledge, this study, which is the largest single-center real-world experience of TAVI in Turkey, demonstrated low complication rates with favorable short- and mid-term THV performance in patients undergoing TAVI.Article Citation - WoS: 2Citation - Scopus: 2Low Carbon Architectural Design(Gazi Univ, 2018) Balku, Saziye; Bal Kocyigit, Filiz; Koçyiğit, Filiz Bal; Architecture; Energy Systems EngineeringTendency towards sustainable energy resources is increasing and leading engineers and architects make joint efforts. Renewable energy potential present in nature can be used more efficiently so that while energy consumption is reducing, rate of energy gain, on the other hand, increases by architectural design methods. A sailing club in Golbasi, Ankara is designed as a low carbon building for optimum usage of solar and wind energy. It can be concluded using an energy efficient architectural design for a building before its construction makes it possible to meet the electrical and heat energy requirements at minimum cost and environmental friendly.Article Citation - WoS: 1Citation - Scopus: 2Cannabinoid Receptor Ligands Modulate Fibrosis and Inflammation in Idiopathic Pulmonary Fibrosis: a Preliminary Study(Tubitak Scientific & Technological Research Council Turkey, 2024) Kose, Sevil; Onen, Selin; Gizer, Merve; Boduroglu, Esin; Gonullu, Ugur; Korkusuz, PetekBackground/aim: No specific pharmacological treatment regimen for idiopathic pulmonary fibrosis (IPF) exists. Therefore, new antiinflammatory therapeutic strategies are needed. Cannabinoids (CBs), known for their inflammation-modulating and antifibrotic effects, may be potential medication candidates for treating IPF. We aim to evaluate the inflammation-modulating and antifibrotic effects of CB receptor (CBR) agonists and antagonists in lipopolysaccharide-stimulated normal human lung fibroblast, epithelial cells, IPF fibroblast cells, and monocytes. Materials and methods: We detected CBRs in normal human lung fibroblasts (LL24) and IPF fibroblast cells (LL29), epithelial cells (A549) and monocytes (THP-1) by flow cytometry. We determined TGF-(31, IL-8, and TNF-alpha inflammatory cytokines in the LL24, LL29, A549, and THP-1 cell culture supernatants on days 1 and 5 by ELISA. We evaluated the cell viability in LL24, LL29, and A549 cells on days 1, 3, and 5 spectrophotometrically and detected collagen Type I (ColI) production in the LL24 and LL29 cell culture supernatants on days 1, 3, and 5 by ELISA. Results: LL24, LL29, A549, and THP-1 cells exhibited CB1 (CB1R) and CB2 (CB2R) receptors. CB1R and CB2R agonists WIN55,2122 and JWH015 inhibited fibroblastic and epithelial cell proliferation on day 5. TGF-(31 and TNF-alpha release increased, while IL-8 release decreased in LL24, LL29, A549, and THP-1 cells in response to the administration of WIN55,212-2 and JWH015 at a 10-2 mM concentration. CB1R and CB2R antagonists AM251 and AM630 did not block agonistic responses, suggesting a nonclassical CBRmediated pathway. CB2R agonist JWH015 decreased ColI expression in IPF lung fibroblasts LL29 on day 3. Conclusion: These results suggest that CB signaling regulates the progression of pulmonary inflammation and fibrosis via CBR activation. This may offer a potential pharmacological tool for developing antifibrosis therapies.Article Citation - WoS: 1Citation - Scopus: 1Bozucu Torklar Altında İzdüşümsel Doğru Akım Motoru Kontrolü(Gazi Univ, Fac Engineering Architecture, 2018) Doruk, Reşat Özgür; Zuglam, İsmail; Doruk, OzgurBu çalışmada, izdüşümsel doğrusal kareselservo geri beslemesi (P-LQSF) yöntemiyle tasarlanmış bir birdoğru akım (DC) motoru denetim yaklaşımı sunulmaktadır. Tasarlanan denetleyicinin kararlılığı girdidenhale-kararlılıkyaklaşımından yola çıkarak incelenmektedir. İzdüşümsel kontrol yöntemi, tam durumdeğişkeni geri beslemeli bir denetleyicinin özdeğer spektrumunu çıktı geri beslemesi kullanarak yaklaşıkolarak elde etmeyi amaçlar. Tasarlanan denetleyicilerin kararlılık analizi hem teorik hem de sayısalbenzetim yoluyla incelenecektir. Temel doğrusal kararlılığın yanı sıra, bozucu etkilerin kapalı döngüyü birdış girdi olarak etkilemesinden yola çıkarak girdiden-çıktıya-kararlılık kavramından yararlanılması olanaklıolabilmektedir. Sonuç olarak bir bozucu etkiden-hale-kararlılık yaklaşımı ortaya çıkmaktadır. Tasarımlar,elde edilen bu yaklaşımla incelenecektir. Performanslar ise sayısal benzetimler yoluyla görülecektir.Article Neuron Modeling: Estimating the Parameters of a Neuron Model From Neural Spiking Data(Tubitak Scientific & Technological Research Council Turkey, 2018) Doruk, Resat Ozgur; Doruk, OzgurWe present a modeling study aiming at the estimation of the parameters of a single neuron model from neural spiking data. The model receives a stimulus as input and provides the firing rate of the neuron as output. The neural spiking data will be obtained from point process simulation. The resultant data will be used in parameter estimation based on the inhomogeneous Poisson maximum likelihood method. The model will be stimulated by various forms of stimuli, which are modeled by a Fourier series (FS), exponential functions, and radial basis functions (RBFs). Tabulated results presenting cases with different sample sizes (# of repeated trials), stimulus component sizes (FS and RBF), amplitudes, and frequency ranges (FS) will be presented to validate the approach and provide a means of comparison. The results showed that regardless of the stimulus type, the most effective parameter on the estimation performance appears to be the sample size. In addition, the lowest variance of the estimates is obtained when a Fourier series stimulus is applied in the estimation.Article Citation - WoS: 20Citation - Scopus: 22Electrochemical and Optical Properties of an Azo Dye Based Conducting Copolymer(Tubitak Scientific & Technological Research Council Turkey, 2009) Cihaner, Atilla; Algi, FatihThe electrochemical and optical properties of a novel conducting copolymer called poly(2,5'-dimethyl-[4-(2,5-di-thiophen-2-yl-pyrrol-1-yl)-phenyl]azobenzene-co-(3,4-ethylenedioxythiophene)) (poly(1-co-EDOT)) are reported. Electrochemically synthesized poly(1-co-EDOT) based on the azo dye has a well-defined and reversible redox couple (0.37 V vs. Ag/AgCl) with good cycle stability. The copolymer film exhibits high conductivity (13 S/cm) as well as electrochromic behavior (magenta when neutralized and transmissive sky blue when oxidized). Furthermore, electro-optically active copolymer film has a low band gap of 1.79 eV with a pi-pi* transition at 555 nm.Article The Early Turkestani Émigré Struggle and Turkestanism: Nation - Imagining in Emigration:1925-1940(2016) Karasar, Hasan AliErken dönem muhaceretteki Türkistanlıların mücadeleleri vatan dışında \"Milli Kimlik Tasavvuru\" oluşturma gayretlerinin önemli bir örneğidir. Bu makalede ülkeleri Bolşevikler tarafından ele geçirildikten sonra vatanlarını terk eden Türkistanlı milliyetçi liderlerin karşılaştıkları fikirsel sorunların bir kısmı ele alınmaktadır. Özellikle de muhaceret liderleri ve Türkçü düşünürlerden Zeki Velidî Togan, Mustafa Çokayoğlu, Osman Hoca ve Nihal Atsız'ın kimlik merkezli tartışmalarına değinilmektedir. Bu çalışmada siyasa yapımı, propaganda taktikleri, dergi neşriyatı ile medya kullanımı ve sivil toplum örgütlenmesi yolları ile muhaceretteki Türkistanlıların Ruslara karşı birleştirilmelerine çalışılmasına öncelik verilmiştir. Muhaceretteki liderlerin vatandan izole ancak vatandaki problemleri yanlarına alarak başlattıkları bu mücadelenin de ana öğelerinden biri kimlik siyaseti olmuştur.Article Citation - WoS: 1Citation - Scopus: 1Mikro Frezeleme İşleminin Takım Eksen Sapması Göz Önüne Alınarak Mekanistik Modellemesi(Gazi Univ, Fac Engineering Architecture, 2018) Karpat, Yiğit; Kanlı, Muammer; Olıaeı, Samad Nadimi Bavilİşlenmesi zor malzemelerden yapılan mikro parçaların hassas üretiminde mikro frezeleme yaygın olarakkullanılan bir yöntemdir. Malzeme işleme hızının yüksek olması ve işleme sonunda iyi yüzey kalitesiüretilmesi bu yöntemin en belirgin avantajlarıdır. Mikro frezeleme işleminin sonuçlarının tahminedilebilmesi için ilk adım hassas bir mekanistik kuvvet modelinin geliştirilmesidir. Mikro frezelemedeoluşan ortalama kesme kuvvetlerinin ilerlemeye göre değişimi makro ölçek frezelemede olduğu gibidoğrusal bir karakteristik göstermez. Bu çalışmada, kübik polinom karakteristiğine sahip ortalama kuvvetmodeline dayalı bir mekanistik model geliştirilmiştir. Ek olarak mikro takımın eksenel sapması geliştirilenmekanistik modele dahil edilmiştir. Geliştirilen model ile titanyum Ti6Al4V alaşımının işlemesi sırasındatahmin edilen kuvvetlerin yapılan ölçümler ile uyumlu olduğu görülmüştür. Farklı işleme şartlarında takımeksenel sapmasının değeri geliştirilen model vasıtası ile araştırılmıştır.Article Modifications of Knuth Randomness Tests for Integer and Binary Sequences(2018) Koçak, Onur; Sulak, Fatih; Doğanaksoy, Ali; Uğuz, MuhiddinGenerating random numbers and random sequences that are in-distinguishable from truly random sequences is an important task for cryptog-raphy. To measure the randomness, statistical randomness tests are applied tothe generated numbers and sequences. Knuth test suite is the one of the .rststatistical randomness suites. This suite, however, is mostly for real numbersequences and the parameters of the tests are not given explicitly.In this work, we review the tests in Knuth Test Suite. We give test para-meters in order for the tests to be applicable to integer and binary sequencesand make suggestions on the choice of these parameters. We clarify how theprobabilities used in the tests are calculated according to the parameters andprovide formulas to calculate the probabilities. Also, some tests, like Per-mutation Test and Max-of-t-test, are modi.ed so that the test can be usedto test integer sequences. Finally, we apply the suite on some widely usedcryptographic random number sources and present the results.
