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Now showing 1 - 10 of 144
  • Article
    Citation - WoS: 13
    Citation - Scopus: 13
    Are Gender-Neutral Pronouns Really Neutral? Testing a Male Bias in the Grammatical Genderless Languages Turkish and Finnish
    (Sage Publications inc, 2023) Renstrom, Emma A.; Lindqvist, Anna; Akbas, Gulcin; Hekanaho, Laura; Senden, Marie Gustafsson
    Languages differ in how grammatically salient gender is. We explored if grammatically gender-neutral pronouns in Finnish and Turkish, two grammatically genderless languages, are gender neutral or male biased, thereby activating male, rather than female, exemplars. We also tested whether differences in national level gender equality influence the male bias. Results indicated a male bias in both languages, whereas national level gender equality had no influence. Implications for gender-fair language reforms in grammatically genderless languages are discussed.
  • Article
    Citation - WoS: 3
    Citation - Scopus: 3
    Synthesis of Silver Nanoparticle-Immobilized Antibacterial Anion-Exchange Membranes for Salinity Gradient Energy Production by Reverse Electrodialysis
    (Amer Chemical Soc, 2024) Eti, Mine; Cihanoglu, Aydin; Hamaloglu, Kadriye Ozlem; Altiok, Esra; Guler, Enver; Tuncel, Ali; Kabay, Nalan
    Biofouling, stemming from the attachment of living microorganisms, such as bacteria, which form resilient biofilms on membrane surfaces, presents a significant challenge that hampers the efficiency of anion-exchange membranes (AEMs) in reverse electrodialysis (RED) applications. This limitation curtails the generation of electrical power from salinity gradients, which notably is a sustainable form of energy known as osmotic energy. RED stands as a clean and promising process to harness this renewable energy source. This study aimed to impart antibacterial activity to synthesized AEMs by using silver nanoparticles (AgNPs). For that purpose, AgNPs were synthesized at 30 degree celsius using two different pH values (6.0 and 9.0) and immobilized into synthesized AEMs using the dip-coating technique. In nanoparticle synthesis, ascorbic acid and trisodium citrate were used as a reductant and a stabilizer, respectively, to take control of the particle size and agglomeration behavior. The results indicated that AgNPs synthesized at pH 6.0 were dispersed on the AEM surface without agglomeration. The stability of AgNPs immobilized on the membrane surface was tested under low- and high-saline solutions. The antibacterial activities of AEMs were determined with the colony-counting method using Gram-negative (Escherichia coli) bacterial suspension. The viability of bacteria dramatically decreased after the immobilization of AgNPs in the AEMs. In the short- and long-term RED tests, it has been observed that the AEMs having AgNPs have high energy-generating potentials, and power density up to 0.372 W/m(2) can be obtained.
  • Article
    Citation - WoS: 11
    Citation - Scopus: 11
    Higher Rates of Cefiderocol Resistance Among Ndm Producing klebsiella Bloodstream Isolates Applying Eucast Over Clsi Breakpoints
    (Taylor & Francis Ltd, 2023) Isler, Burcu; Vatansever, Cansel; Ozer, Berna; Cinar, Gule; Aslan, Abdullah Tarik; Falconer, Caitlin; Harris, Patrick N. A.
    BackgroundCefiderocol is generally active against carbapenem-resistant Klebsiella spp. (CRK) with higher MICs against metallo-beta-lactamase producers. There is a variation in cefiderocol interpretive criteria determined by EUCAST and CLSI. Our objective was to test CRK isolates against cefiderocol and compare cefiderocol susceptibilities using EUCAST and CLSI interpretive criteria.MethodsA unique collection (n = 254) of mainly OXA-48-like- or NDM-producing CRK bloodstream isolates were tested against cefiderocol with disc diffusion (Mast Diagnostics, UK). Beta-lactam resistance genes and multilocus sequence types were identified using bioinformatics analyses on complete bacterial genomes.ResultsMedian cefiderocol inhibition zone diameter was 24 mm (interquartile range [IQR] 24-26 mm) for all isolates and 18 mm (IQR 15-21 mm) for NDM producers. We observed significant variability between cefiderocol susceptibilities using EUCAST and CLSI breakpoints, such that 26% and 2% of all isolates, and 81% and 12% of the NDM producers were resistant to cefiderocol using EUCAST and CLSI interpretive criteria, respectively.ConclusionsCefiderocol resistance rates among NDM producers are high using EUCAST criteria. Breakpoint variability may have significant implications on patient outcomes. Until more clinical outcome data are available, we suggest using EUCAST interpretive criteria for cefiderocol susceptibility testing.
  • Article
    A Benchmark of Expert-Level Academic Questions to Assess AI Capabilities
    (Nature Portfolio, 2026) Phan, Long; Gatti, Alice; Li, Nathaniel; Khoja, Adam; Kim, Ryan; Ren, Richard; Scaramuzza, Davide; Park, Jongee
    Benchmarks are important tools for tracking the rapid advancements in large language model (LLM) capabilities. However, benchmarks are not keeping pace in difficulty: LLMs now achieve more than 90% accuracy on popular benchmarks such as Measuring Massive Multitask Language Understanding(1), limiting informed measurement of state-of-the-art LLM capabilities. Here, in response, we introduce Humanity's Last Exam (HLE), a multi-modal benchmark at the frontier of human knowledge, designed to be an expert-level closed-ended academic benchmark with broad subject coverage. HLE consists of 2,500 questions across dozens of subjects, including mathematics, humanities and the natural sciences. HLE is developed globally by subject-matter experts and consists of multiple-choice and short-answer questions suitable for automated grading. Each question has a known solution that is unambiguous and easily verifiable but cannot be quickly answered by internet retrieval. State-of-the-art LLMs demonstrate low accuracy and calibration on HLE, highlighting a marked gap between current LLM capabilities and the expert human frontier on closed-ended academic questions. To inform research and policymaking upon a clear understanding of model capabilities, we publicly release HLE at https://lastexam.ai.
  • Article
    Citation - WoS: 24
    Citation - Scopus: 27
    Effect of Solution Heat Treatment on the Microstructure and Crystallographic Texture of In939 Fabricated by Powder Bed Fusion-Laser Beam
    (Elsevier, 2023) Dogu, Merve Nur; Ozer, Seren; Yalcin, Mustafa Alp; Davut, Kemal; Bilgin, Guney Mert; Obeidi, Muhannad Ahmed; Brabazon, Dermot
    The effect of various solution heat treatment temperatures (i.e., 1120, 1160, 1200 and 1240 & DEG;C) on the microstructure, grain morphology and crystallographic texture of IN939 fabricated by powder bed fusion-laser beam (PBF-LB) was investigated. Microstructural analyses showed that the high-temperature gradient and rapid solidification of the PBF-LB processing caused different resulting microstructures compared to conventionally pro-duced counterparts. The melt pool morphologies and laser scanning paths were examined in the as-fabricated samples in the XZ-and XY-planes, respectively. After the application of solution heat treatment at 1120 & DEG;C, the as-fabricated PBF-LB initial microstructure was still apparent. For solution heat treatments of 1200 & DEG;C and above, the melt pool and scanning path morphologies disappeared and converted into a mixture of columnar grains in the XZ-plane and equiaxed grains in the XY-plane. On the other hand, large equiaxed grains were observed when the samples were solutionized at 1240 & DEG;C. Additionally, g' phase precipitated within the matrix after all solution heat treatment conditions, which led to increase in the microhardness values. According to electron backscatter diffraction (EBSD) analyses, both as-fabricated and solution heat-treated samples had intense texture with {001} plane normal parallel to the building direction. The first recrystallized grains began to appear when the samples were subjected to the solution heat treatment at 1160 & DEG;C and the fraction of the recrystallized grains increased with increasing temperature, as supported by kernel average misorientation (KAM) and grain spread orientation (GOS) analyses.& COPY; 2023 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
  • Article
    Citation - WoS: 28
    Citation - Scopus: 31
    A Model for the Prediction of Thermal Runaway in Lithium-Ion Batteries
    (Elsevier, 2024) Azuaje-Berbeci, Bernardo J.; Ertan, H. Bulent
    The increasing popularity of electric vehicles is driving research into lithium -ion batteries (LIBs). Thermal runaway (TR) in LIBs is a serious concern for the safe operation of these high-energy-density batteries that is yet to be overcome. A reliable model is needed to predict voltage variation, heat generation, temperature rise, and the process leading to TR of a LIB battery under its operating conditions (charging-discharging). Such a model can be used to design battery packs more resilient to thermal runaway or assess how a battery pack would perform under hazardous conditions. Furthermore, it can be used for generating a warning signal if there is a possibility of the battery going towards TR. This paper presents an approach to solving this problem, which is not currently well addressed in the literature. The approach adopted in this paper is based on a numerical analysis of a multilayered electrochemical-thermal model of LIB. Tuning the parameters of a LIB for accurate results from this numerical model is presented, as well as the details of the approach in the paper. Experiments are performed under several LIBs, and their voltage and surface temperature variations are measured under various operating conditions, including thermal runaway. The results of the experiments are compared with the predictions of the numerical simulations. An excellent agreement is observed with the experimental results, proving the accuracy of the proposed approach. This approach can be configured to give results in a few minutes. The paper also discusses how the developed approach can be used to create a TR warning during operating conditions or to change the mode of operation of a LIB before a hazard occurs.
  • Article
    Citation - WoS: 4
    Citation - Scopus: 4
    Effects of Cerium Oxide on Kidney and Liver Tissue Damage in an Experimental Myocardial Ischemia-Reperfusion Model of Distant Organ Damage
    (Mdpi, 2024) Gunes, Isin; Dursun, Ali Dogan; Ozdemir, Cagri; Kucuk, Aysegul; Sezen, Saban Cem; Arslan, Mustafa; Ozer, Abdullah
    Background and Objectives: Ischemia-reperfusion (I/R) injury is a process in which impaired perfusion is restored by restoring blood flow and tissue recirculation. Nanomedicine uses cutting-edge technologies that emerge from interdisciplinary influences. In the literature, there are very few in vivo and in vitro studies on how cerium oxide (CeO2) affects systemic anti-inflammatory response and inflammation. Therefore, in our study, we aimed to investigate whether CeO2 administration has a protective effect against myocardial I/R injury in the liver and kidneys. Materials and Methods: Twenty-four rats were randomly divided into four groups after obtaining approval from an ethics committee. A control (group C), cerium oxide (group CO), IR (group IR), and Cerium oxide-IR (CO-IR group) groups were formed. Intraperitoneal CeO2 was administered at a dose of 0.5 mg/kg 30 min before left thoracotomy and left main coronary (LAD) ligation, and myocardial muscle ischemia was induced for 30 min. After LAD ligation was removed, reperfusion was performed for 120 min. All rats were euthanized using ketamine, and blood was collected. Liver and kidney tissue samples were evaluated histopathologically. Serum AST (aspartate aminotransferase), ALT (alanine aminotransaminase), GGT (gamma-glutamyl transferase), glucose, TOS (Total Oxidant Status), and TAS (Total Antioxidant Status) levels were also measured. Results: Necrotic cell and mononuclear cell infiltration in the liver parenchyma of rats in the IR group was observed to be significantly increased compared to the other groups. Hepatocyte degeneration was greater in the IR group compared to groups C and CO. Vascular vacuolization and hypertrophy, tubular degeneration, and necrosis were increased in the kidney tissue of the IR group compared to the other groups. Tubular dilatation was significantly higher in the IR group than in the C and CO groups. TOS was significantly higher in all groups than in the IR group (p < 0.0001, p < 0.0001, and p = 0.006, respectively). However, TAS level was lower in the IR group than in the other groups (p = 0.002, p = 0.020, and p = 0.031, respectively). Renal and liver histopathological findings decreased significantly in the CO-IR group compared to the IR group. A decrease in the TOS level and an increase in the TAS level were found compared to the IR group. The AST, ALT, GGT, and Glucose levels are shown. Conclusions: CeO2 administered before ischemia-reperfusion reduced oxidative stress and ameliorated IR-induced damage in distant organs. We suggest that CeO2 exerts protective effects in the myocardial IR model.
  • Article
    The Effect of a Single Session Rubber Hand Illusion on Pressure Pain Is Not Long-Lasting
    (John Wiley and Sons Inc, 2025) Ceylan, H.; Acet, N.; Günendi, Z.
    Background: Rubber hand illusion (RHI) is an experience that causes changes in body perception and awareness as a result of the integration of simultaneous perceived visual and tactile stimuli. After synchronous brush strokes with rubber and real hands, the person perceives the rubber hand as their own. RHI is known to alter pain perception. In this study, it was aimed to evaluate the effects of RHI on pressure pain threshold and continuity of this effect. Methods: Twenty-three volunteers who developed RHI were included in our study and two conditions, illusion (synchronous) and control (asynchronous), were applied. The illusion condition was created by synchronous brush strokes, while the control condition was created by asynchronous brush application using different frequency and different finger areas in the same individuals. In both conditions, pressure pain threshold measurements with an algometer were performed at four times: baseline/1st measurement, during the brush stroke/2nd measurement, at the end of the brush stroke/3rd measurement and after the hand was removed from the environment/4th measurement. Results: It was shown that RHI increased the pressure-pain threshold (p = 0.004) in healthy volunteers. Asynchronous brush strokes arranged as a control trial significantly decreased the pressure pain threshold (p = 0.002). Conclusions: It was found that the threshold values that change during the brush strokes return to the initial state after the brush strokes are terminated and the rubber hand is removed from the environment so that the effect of the illusion does not last for a long time with a single session application. © 2025 European Pain Federation - EFIC ®.
  • Article
    Exploring the Role of Search Experience and Self-Efficacy in Cognitive Self-Esteem: a Latent Growth Modelling Approach
    (Sage Publications inc, 2025) Akgun, Mahir; Toker, Sacip
    In this study, we seek to contribute to a broader understanding of the processes and contexts that lead to inflated judgments of cognitive ability in human-computer partnerships. We conducted a within-subject experiment design study with 164 college students in order to explore the impact of the search experience on cognitive self-esteem (CSE). Our preliminary findings revealed that search experience is an important factor that influences individuals' perception of their abilities to answer questions. This influence was observed regardless of whether they have access to search tools or not. However, search experience does not explain the significant change in CSE that we found between "access" and "no access" (to search tools) conditions.
  • Article
    Citation - WoS: 5
    Citation - Scopus: 3
    Investigation of Λ (1405)as a molecular pentaquark state
    (Springer, 2024) Azizi, K.; Sarac, Y.; Sundu, H.
    Lambda ( 1405 ) is one of the interesting particles with its unclear structure and distinct properties. It has a light mass compared to its non-strange counterpart, despite the strange quark it carries. This situation puts the investigation of this resonance among the hot topics in hadron physics and collects attention to clarify its properties. In this study, we focus on the calculation of the mass and residue of the Lambda ( 1405 ) resonance within the framework of QCD sum rules. We assign a structure in the form of a molecular pentaquark composed from admixture of K - meson-neutron. Using an interpolating current in this form, the masses and the current coupling constant are attained as m = 1406 +/- 128 MeV and lambda = ( 3.35 +/- 0.35 ) x 10( - 5) GeV 6 for q and m = 1402 +/- 141 MeV and lambda = ( 4.08 +/- 1.08 ) x 10( - 5) GeV 6 for I Lorentz structures entering the calculations, respectively. The obtained mass values agree well with the experimental data supporting the plausibility of the considered structure.