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Now showing 1 - 10 of 173
  • Review
    Citation - WoS: 7
    Citation - Scopus: 8
    Stereotactic Radiosurgery After Subtotal Resection of Critically-Located Grade I Meningioma: a Single-Center Experience and Review of Literature
    (Turkish Neurosurgical Soc, 2021) Karaaslan, Burak; Celtikci, Emrah; Bulduk, Erkut Baha; Borcek, Alp Ozgun; Kurt, Gokhan; Kaymaz, Memduh; Emmez, Hakan
    AIM: To analyze the results of stereotactic radiosurgery in 295 patients with residual Grade I meningiomas located at parasellar region, petroclival region, cerebellopontine angle and parasagittal region. MATERIAL and METHODS: A total of 295 patients with Grade 1 residual Meningiomas (197 women, 98 men), who were treated by adjuvant radiosurgery in Gazi University Gamma Knife Center between 2004-2015 were analyzed. WHO Grade 2 and 3 meningiomas were not included in our study. Minimum radiological follow-up was 24 months. The median follow-up was 54 months. The tumor volume, location, treatment dose, morbidity, progression free survival and tumor control rate were analyzed. RESULTS: The median tumor volume was 5.2 cm(3) (0.04-39.7), median age was 50 (20-80), median dose was 14 Gy and tumor control rate was 94.5% (stationary in 85.0%, volume reduction in 9.5%). Increase in tumor volume was seen in 16 patients (5.5%) and re-operation was performed in 5 of them (1.6%). Stereotactic radiosurgery was performed again for 8 patients (2.7%).The location of the tumors was as follows: 39.3% parasellar region, 20% cerebellopontine angle, 13.6% petroclival and 27.1% was parasagittal, falcine or convexity. Major morbidities were detected in 6 (2%) patients. Minor morbidities were detected in 18 (6.1%) patients. CONCLUSION: Stereotactic radiosurgery is an effective and safe treatment modality for residual Grade I meningiomas.
  • Review
    Citation - WoS: 6
    Binary Alloy Clusters: Structures and Electronic Properties
    (Amer Scientific Publishers, 2014) Pekoez, Rengin; Oymak, Hueseyin; Erkoc, Akir
    Synthesis, characterization, physics, and chemistry of nanoclusters have been the focus of intense attention for the last two decades. Also, their unique statues that they are between molecule and bulk material is the central reason for the theoretical researcher to understand the transition from atom to cluster/molecule and then to solid state. In this review we restrict ourselves to the recent advances in the structural and electronic properties of binary alloy clusters. This type of clusters is particularly of importance thanks to their very availability for being tuned, by changing their sizes, according to any special needs. A brief summary of the classification of clusters as well as the experimental techniques and theoretical methods to study them, and the possible applications of alloy clusters are given in the introduction part. Several binary alloy cluster types, including semiconductor, alkali and transition metal, oxide, and ionic binary alloy clusters, are widely reviewed considering extensively the most recent articles.
  • Review
    Citation - WoS: 88
    Citation - Scopus: 96
    Vision 2023: Forecasting Turkey's Natural Gas Demand Between 2013 and 2030
    (Pergamon-elsevier Science Ltd, 2013) Melikoglu, Mehmet
    Natural gas is the primary source for electricity production in Turkey. However, Turkey does not have indigenous resources and imports more than 98.0% of the natural gas it consumes. In 2011, more than 20.0% of Turkey's annual trade deficit was due to imported natural gas, estimated at US$ 20.0 billion. Turkish government has very ambitious targets for the country's energy sector in the next decade according to the Vision 2023 agenda. Previously, we have estimated that Turkey's annual electricity demand would be 530,000 GWh at the year 2023. Considering current energy market dynamics it is almost evident that a substantial amount of this demand would be supplied from natural gas. However, meticulous analysis of the Vision 2023 goals clearly showed that the information about the natural gas sector is scarce. Most importantly there is no demand forecast for natural gas in the Vision 2023 agenda. Therefore, in this study the aim was to generate accurate forecasts for Turkey's natural gas demand between 2013 and 2030. For this purpose, two semi-empirical models based on econometrics, gross domestic product (GDP) at purchasing power parity (PPP) per capita, and demographics, population change, were developed. The logistic equation, which can be used for long term natural gas demand forecasting, and the linear equation, which can be used for medium term demand forecasting, fitted to the timeline series almost seamlessly. In addition, these two models provided reasonable fits according to the mean absolute percentage error, MAPE %, criteria. Turkey's natural gas demand at the year 2030 was calculated as 76.8 billion m(3) using the linear model and 83.8 billion m(3) based on the logistic model. Consequently, found to be in better agreement with the official Turkish petroleum pipeline corporation (BOTAS) forecast, 76.4 billion m(3), than results published in the literature. (C) 2013 Elsevier Ltd. All rights reserved.
  • Review
    Milli Mücadele Döneminde Ayrılıkçı Faaliyetlerde Kilisenin Rolü ve Hrisostomos-hrisantos Girişimlerine Kesitsel Bir Bakış
    (2010) Keser, Ulvi
    1919–1922 süreci Anadolu’da Milli Mücadele’ninyaşandığı bir dönemdir. 30 Ekim 1918 sonrasındaİngiltere, Fransa, İtalya arasında paylaşılmaya başlanılanAnadolu topraklarında 15 Mayıs 1919 tarihinde başlayanYunan işgaliyle birlikte işgal, isyan ve mücadele iç içegirer. Bu dönemde silahlı mücadele yanında özellikleYunan kilisesinin etkili rolü de kendisini göstermeyebaşlar. Megali İdea düşüncesi doğrultusunda BüyükYunanistan kurma hayali bir kere daha canlanır veAnadolu’nun iki farklı noktasında olmak üzere MetropolitHrisostomos İzmir ve Batı Anadolu’da, MetropolitHrisantos ise Trabzon ve Karadeniz bölgesinde işgal vekıyım hareketlerine öncülük eder, halkı kışkırtır ve Megaliİdea rüyasının gerçekleşmesi için var gücüyle çalışır. Buçalışma her iki metropolitin İzmir ve Trabzonbölgelerindeki faaliyetlerini ve amaç birliği çerçevesindeyaptıkları çabaları ortaya koymak amacıylahazırlanmıştır.
  • Review
    Citation - WoS: 35
    Citation - Scopus: 38
    Aptamer Hybrid Nanocomplexes as Targeting Components for Antibiotic/Gene Delivery Systems and Diagnostics: a Review
    (Dove Medical Press Ltd, 2020) Rabiee, Navid; Ahmadi, Sepideh; Arab, Zeynab; Bagherzadeh, Mojtaba; Safarkhani, Moein; Nasseri, Behzad; Tayebi, Lobat; Rabiee, Mohammad; Tahriri, Mohammadreza
    With the passage of time and more advanced societies, there is a greater emergence and incidence of disease and necessity for improved treatments. In this respect, nowadays, aptamers, with their better efficiency at diagnosing and treating diseases than antibodies, are at the center of attention. Here, in this review, we first investigate aptamer function in various fields (such as the detection and remedy of pathogens, modification of nanoparticles, antibiotic delivery and gene delivery). Then, we present aptamer-conjugated nanocomplexes as the main and efficient factor in gene delivery. Finally, we focus on the targeted co-delivery of genes and drugs by nanocomplexes, as a new exciting approach for cancer treatment in the decades ahead to meet our growing societal needs.
  • Review
    Citation - WoS: 1
    Evolution of the Relationship Between Urban Planning and Urban Infrastructure
    (Kare Publ, 2018) Sahin, Savas Zafer
    In the face of disasters caused by climate change and ecological degradation, the future of cities has become closely interrelated with the sensitive balance between urban planning and urban infrastructure. Integrated sustainable urban planning and management approaches, where the relationship between urban planning and urban infrastructure is re-examined to manage urban risks, manage the capacity of existing infrastructure, and adapt to climate change have been discussed for a long time. Particularly in the last 2 to 3 decades, in various countries and for different reasons, urban planning and urban infrastructure investments have diverged. Under the influence of neo-liberal policies, the urban planning process has often been transformed into a mechanism of re-distributing urban rents via urban projects, and urban infrastructure investments are presented to society as mega projects to help legitimize the effects of this transformation politically. This dissociation results in an inefficient and ineffective use of resources, a negative effect on the urban ecosystem, and an urban daily life that is fragile and disrupted. The development of a framework that re-integrates planning with infrastructure is an inevitable necessity.
  • Review
    Citation - WoS: 59
    Citation - Scopus: 66
    Application of Minimum Quantity Lubrication Techniques in Machining Process of Titanium Alloy for Sustainability: a Review
    (Springer London Ltd, 2019) Osman, Khaled Ali; Unver, Hakki Ozgur; Seker, Ulvi
    Recently, the manufacturing sector is increasingly keen to apply sustainability at all levels of sustainability from system to products and processes. At the processes level, cutting fluids (CFs) are among the most unsustainable materials and need to be addressed properly in accordance with three main and decisive aspects, also known as the triple bottom line: ecology, society, and economics. Minimum quantity lubrication (MQL) is a promising technique that minimizes the use of CFs, thus improving sustainability. This paper presents a review of the literature available on the use of the MQL technique during different machining processes involving titanium alloys (Ti-6Al-4V). To carry out the study, four search engines were used to focus on the most cited articles published over a span of 17years from 2000 to 2016. The performance and drawbacks are compiled for each eco-friendly technique: dry, MQL, and cryogenics with combinations of MQL and cryogenics, critically considering machining parameters such as cutting speed, feed rate, and output measures, namely surface roughness, tool life, and cutting temperature. After drawing conclusions from critical evaluation of research body, future research avenues in the field are proposed for the academics and industry.
  • Review
    KORONAVİRÜS (COVİD-19) SALGINI NEDENİYLE OKUL SINIFI ORTAMLARININ EV TABANLI SINIF ORTAMLARINA DÖNÜŞÜMÜ
    (2021) Güneş, Elif; Ünal, Bülent; Memikoğlu, İpek
    Özellikle küçük çocuklar için eğitim alanları, okul öncesi ve ilkokulun en küçük çocuklar içinkullandıkları ve anında tanıdıkları ilk halka açık yerler olduğu için mekânsal algılarında en büyüketkiye sahip mekânlardır. Okul binalarında renk, aydınlatma, akustik, havalandırma ve sıcaklık gibifiziksel mimari parametreler, öğrenci ve öğretmenlerin davranışları, refahları ve kazanımlarıüzerinde önemli etkilere sahiptir. Günümüz COVID-19 salgın koşullarında sınıf ortamlarınınbilgisayar ekranlarına dönüşmesi ile fiziksel eğitim ortamları aniden bilgisayar ekranlarınataşınmış ve eğitim alanlarındaki sınıf ortamları, evin herhangi bir alanına taşınmıştır. Yani, uzaktaneğitim süreci ile öğrencilerin eğitim ortamı değişim yaşamıştır. Eğitim mekânlarında çocuklarınkonsantrasyonu, üretkenliği ve refahı açısından alınması gereken önemli tasarım kararları varken,bu durum bilgisayar ekranının başrol oynadığı evde yeni oluşturulan sınıflarda da geçerlidir. Buçalışmanın amacı, bu ev eğitim ortamlarının fiziksel mimari ve tasarım parametreleri açısındanampirik ve teorik kanıtlar ışığında nasıl yaratılması gerektiğine dair bilgi sağlamaktır. Bu amacaulaşmak için bu araştırmanın temel yöntemi evde oluşturulabilecek eğitim ortamları için birmodel sunmaktır.
  • Review
    Çikolata ve Sağlık Beyanları
    (2018) Cömert, Tuğba Küçükkasap; Merdol, Türkan Kutluay
    Çikolata, bileşimindeki kakao oranı ve yapımında kullanılan maddelere göre bitter çikolata, sütlü çikolata vb. olarakadlandırılır. Kakao oranı ile en zengin olan bitter çikolatanın sağlık üzerine etkileri pek çok çalışmada değerlendirilmişancak tutarlı sonuçlar elde edilememiştir. Bazı araştırmalar, kakaonun yararlı etkisinin ancak çiğ tüketimi ile mümkünolabileceğini vurgularken, bazıları bitter çikolatanın yüksek doymuş yağ ve şeker içeriği nedeniyle vücut ağırlığında artışaneden olabileceğine dikkat çekmektedir. Bunun yanı sıra, kakao ve çikolata, teobromin ve kafein içeriğinden dolayı, belirginyüksek nabız ile ilişkilendirilmekte, bu nedenle aritmisi olanlarda ve yaşlı hastalarda tüketiminin kısıtlanması gerektiğibelirtilmektedir. Bununla birlikte, çikolatanın olumlu etkileri olduğunu gösteren bir çok çalışma da bulunmaktadır.Bu çalışmalarda, çikolatada bulunan sağlıksız bileşenlere karşılık, olumlu etkilerinin değerlendirilmesi gerektiğivurgulanmakta, istenmeyen olumsuz etkileri engellemek için uygun miktarlarda tüketilmesi gerektiği belirtilmektedir. Buderlemede, çikolata ve sağlık beyanları üzerine yapılan çalışmalar ve sonuçları değerlendirilmiştir.