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Article Citation - WoS: 24Citation - Scopus: 27The Pimpled Gold Nanosphere: a Superior Candidate for Plasmonic Photothermal Therapy(Dove Medical Press Ltd, 2020) Nasseri, Behzad; Turk, Mustafa; Kosemehmetoglu, Kemal; Kaya, Murat; Piskin, Erhan; Rabiee, Navid; Webster, Thomas J.Background: The development of highly efficient nanoparticles to convert light to heat for anti-cancer applications is quite a challenging field of research. Methods: In this study, we synthesized unique pimpled gold nanospheres (PGNSs) for plasmonic photothermal therapy (PPTT). The light-to-heat conversion capability of PGNSs and PPTT damage at the cellular level were investigated using a tissue phantom model. The ability of PGNSs to induce robust cellular damage was studied during cytotoxicity tests on colorectal adenocarcinoma (DLD-1) and fibroblast cell lines. Further, a numerical model of plasmonic (COMSOL Multiphysics) properties was used with the PPTT experimental assays. Results: A low cytotoxic effect of thiolated polyethylene glycol (SH-PEG400-SH-) was observed which improved the biocompatibility of PGNSs to maintain 89.4% cell viability during cytometry assays (in terms of fibroblast cells for 24 hrs at a concentration of 300 mu g/mL). The heat generated from the nanoparticle-mediated phantom models resulted in Delta T=30 degrees C, Delta T=23.1 degrees C and Delta T=21 degrees C for the PGNSs, AuNRs, and AuNPs, respectively (at a 300 mu g/mL concentration and for 325 sec). For the in vitro assays of PPTT on cancer cells, the PGNS group induced a 68.78% lethality (apoptosis) on DLD-1 cells. Fluorescence microscopy results showed the destruction of cell membranes and nuclei for the PPTT group. Experiments further revealed a penetration depth of sufficient PPTT damage in a physical tumor model after hematoxylin and eosin (H&E) staining through pathological studies (at depths of 2, 3 and 4 cm). Severe structural damages were observed in the tissue model through an 808-nm laser exposed to the PGNSs. Conclusion: Collectively, such results show much promise for the use of the present PGNSs and photothermal therapy for numerous anti-cancer applications.Article Citation - WoS: 13Citation - Scopus: 16An Analytic Network Process Based Risk Assessment Model for Ppp Hydropower Investments(Vilnius Gediminas Tech Univ, 2021) Akcay, Emre CanerThe number of public-private partnership (PPP) projects has gone up especially in developing countries. The risk assessment of PPP projects is essential in ensuring project success. The objective of this study is to develop an Analytic Network Process (ANP) based risk assessment model for hydropower investments, and a tool to facilitate quantification of risk ratings based on this model. The results show that the three most important risk factors that affect the overall risk rating of a PPP hydropower investment are legal risks, contractor/subcontractor risks, and operator risks. In addition, the three most important risk clusters were identified as stakeholders, government requirements, and resources, whereas market was the least important cluster. The tool that measures the risk rating of a PPP of hydropower project was tested on ten real cases, and satisfactory results were obtained in terms of its predictive capability. The contributions of this research include (1) identification of the risk factors and clusters of factors associated with PPP hydropower investments; (2) determination of the priority of each risk factor and cluster; (3) development a tool that guides the investors through the risk assessment of PPP hydropower investments.Article Citation - WoS: 58Fast Neutron Imaging With Semiconductor Nanocrystal Scintillators(Amer Chemical Soc, 2020) McCall, Kyle M.; Sakhatskyi, Kostiantyn; Lehmann, Eberhard; Walfort, Bernhard; Losko, Adrian S.; Montanarella, Federico; Kovalenko, Maksym, VFast neutrons offer high penetration capabilities for both light and dense materials due to their comparatively low interaction cross sections, making them ideal for the imaging of large-scale objects such as large fossils or as-built plane turbines, for which X-rays or thermal neutrons do not provide sufficient penetration. However, inefficient fast neutron detection limits widespread application of this technique. Traditional phosphors such as ZnS:Cu embedded in plastics are utilized as scintillators in recoil proton detectors for fast neutron imaging. However, these scintillation plates exhibit significant light scattering due to the plastic-phosphor interface along with long-lived afterglow (on the order of minutes), and therefore alternative solutions are needed to increase the availability of this technique. Here, we utilize colloidal nanocrystals (NCs) in hydrogen-dense solvents for fast neutron imaging through the detection of recoil protons generated by neutron scattering, demonstrating the efficacy of nanomaterials as scintillators in this detection scheme. The light yield, spatial resolution, and neutron-vs-gamma sensitivity of several chalcogenide (CdSe and CuInS2)-based and perovskite halide-based NCs are determined, with only a short-lived afterglow (below the order of seconds) observed for all of these NCs. FAPbBr(3) NCs exhibit the brightest total light output at 19.3% of the commercial ZnS:Cu(PP) standard, while CsPbBrCl2:Mn NCs offer the best spatial resolution at similar to 2.6 mm. Colloidal NCs showed significantly lower gamma sensitivity than ZnS:Cu; for example, 79% of the FAPbBr(3) light yield results from neutron-induced radioluminescence and hence the neutron-specific light yield of FAPbBr(3) is 30.4% of that of ZnS:Cu(PP). Concentration and thickness-dependent measurements highlight the importance of increasing concentrations and reducing self-absorption, yielding design principles to optimize and foster an era of NC-based scintillators for fast neutron imaging.Article Citation - WoS: 39Citation - Scopus: 44A Novel Treatment Strategy for Preterm Birth: Intra-Vaginal Progesterone-Loaded Fibrous Patches(Elsevier, 2020) Cam, Muhammet Emin; Hazar-Yavuz, Ayse Nur; Cesur, Sumeyye; Ozkan, Ozan; Alenezi, Hussain; Sasmazel, Hilal Turkoglu; Edirisinghe, MohanProgesterone-loaded poly(lactic) acid fibrous polymeric patches were produced using electrospinning and pressurized gyration for infra-vaginal application to prevent preterm birth. The patches were intravaginally inserted into rats in the final week of their pregnancy, equivalent to the third trimester of human pregnancy. Maintenance tocolysis with progesterone-loaded patches was elucidated by recording the contractile response of uterine smooth muscle to noradrenaline in pregnant rats. Both progesterone-loaded patches indicated similar results from release and thermal studies, however, patches obtained by electrospinning had smaller average diameters and more uniform dispersion compared to pressurized gyration. Patches obtained by pressurized gyration had better results in production yield and tensile strength than electrospinning; thereby pressurized gyration is better suited for scaled-up production. The patches did not affect cell attachment, viability, and proliferation on Vero cells negatively. Consequently, progesterone-loaded patches are a novel and successful treatment strategy for preventing preterm birth.Article Citation - WoS: 19Citation - Scopus: 21Lyapunov Type Inequalities for Mixed Nonlinear Riemann-Liouville Fractional Differential Equations With a Forcing Term(Elsevier, 2017) Agarwal, Ravi P.; Ozbekler, AbdullahIn this paper, we present some new Lyapunov and Hartman type inequalities for Riemann-Liouville fractional differential equations of the form ((a)D(alpha)x)(t) + p(t) vertical bar x(t) vertical bar(mu-1) x(t) + q(t) vertical bar x(t) vertical bar(gamma-1) x(t) = f(t), where p, q, f are real-valued functions and 0 < gamma < 1 < mu < 2. No sign restrictions are imposed on the potential functions p, q and the forcing term f. The inequalities obtained generalize and compliment the existing results for the special cases of this equation in the literature. (C) 2016 Elsevier B.V. All rights reserved.Article Queer Lives in the Social Media Prism: Precarious LGBTQIA Plus Visibility and Lateral Surveillance in Azerbaijan(Sage Publications Inc, 2025) Seyidov, Ilgar; Pentzold, ChristianIn countries where state institutions and the public largely reject LGBTQIA+ identities and issues, queer people struggle with visibility. Next to governments and technology providers, what queer people do, who they connect to, and how they express themselves is being watched and scrutinized by their families and proximate relations. This lateral surveillance is afforded by social media that establish, as we argue in this article, a prism. Here, LGBTQIA+ lives become refracted as extensive though incoherent patterns of digital traces. How queer people respond to this situation where the binary of visible versus invisible falls apart is poorly understood. To address that gap, we interrogate the precarious management of visibility attempted by LGBTQIA+ people in Azerbaijan with its heteropatriarchal, honor-driven culture. Based on our exploratory interview study, we find that queer Azerbaijanis were confronted with a highly ambivalent scopic setup where context collision loomed large. In effect, they supported LGBTQIA+ visibility but had personally decided not to live or promote it. Yet whilst their attempts to remain opaque may contradict their activistic compliancy, this was a logical reaction to too hard to handle terms of visibility.Correction Characterization of Lead Glazed Potteries From Smyrna (izmir/Turkey) Using Multiple Analytical Techniques; Part I: Glaze and Engobe (vol 40, Pg 2143, 2014)(Elsevier Sci Ltd, 2014) Ozcatal, M.; Yaygingol, M.; Issi, A.; Kara, A.; Turan, S.; Okyar, F.; Minceva-Sukarova, B.[No Abstract Available]Article Citation - WoS: 4Citation - Scopus: 7Clinical Characteristics of Patients With Intraocular Lens Calcification After Pars Plana Vitrectomy(Mdpi, 2023) Bopp, Silvia; Ozdemir, Huseyin Baran; Aktas, Zeynep; Khoramnia, Ramin; Yildirim, Timur M.; Schickhardt, Sonja; Ozdek, SengulAim: To determine the clinical risk factors that may increase the occurrence of intraocular lens (IOL) calcification in patients who had undergone pars plana vitrectomy (PPV). Methods: The medical records of 14 patients who underwent IOL explantation due to clinically significant IOL opacification after PPV were reviewed. The date of primary cataract surgery, technique and implanted IOL characteristics; the time, cause and technique of PPV; tamponade used; additional surgeries; the time of IOL calcification and explantation; and IOL explantation technique were investigated. Results: PPV had been performed as a combined procedure with cataract surgery in eight eyes and solely in six pseudophakic eyes. The IOL material was hydrophilic in six eyes, hydrophilic with a hydrophobic surface in seven eyes and undetermined in one eye. The endotamponades used during primary PPV were C2F6 in eight eyes, C3F8 in one eye, air in two eyes and silicone oil in three eyes. Two of three eyes underwent subsequent silicone oil removal and gas tamponade exchange. Gas in the anterior chamber was detected in six eyes after PPV or silicone oil removal. The mean interval between PPV and IOL opacification was 20.5 +/- 18.6 months. The mean BCVA in logMAR was 0.43 +/- 0.42 after PPV, which significantly decreased to 0.67 +/- 0.68 before IOL explantation for IOL opacification (p = 0.007) and increased to 0.48 +/- 0.59 after the IOL exchange (p = 0.015). Conclusions: PPV with endotamponades in pseudophakic eyes, particularly gas, seems to increase the risk for secondary IOL calcification, especially in hydrophilic IOLs. IOL exchange seems to solve this problem when clinically significant vision loss occurs.Article Citation - WoS: 172Citation - Scopus: 190Interpolative Reich-Rus Type Contractions on Partial Metric Spaces(Mdpi, 2018) Karapinar, Erdal; Agarwal, Ravi; Aydi, HassenBy giving a counter-example, we point out a gap in the paper by Karapinar (Adv. Theory Nonlinear Anal. Its Appl. 2018, 2, 85-87) where the given fixed point may be not unique and we present the corrected version. We also state the celebrated fixed point theorem of Reich-Rus-Ciric in the framework of complete partial metric spaces, by taking the interpolation theory into account. Some examples are provided where the main result in papers by Reich (Can. Math. Bull. 1971, 14, 121-124; Boll. Unione Mat. Ital. 1972, 4, 26-42 and Boll. Unione Mat. Ital. 1971, 4, 1-11.) is not applicable.Article Citation - WoS: 31Citation - Scopus: 30Structure of the Ξb< Resonance(Amer Physical Soc, 2018) Aliev, T. M.; Azizi, K.; Sarac, Y.; Sundu, H.We explore the recently observed Xi(b)(6227)(-) resonance to fix its quantum numbers. To this end, we consider various possible scenarios: It can be considered as either a 1P or 2S excitation of the Xi(b) and Xi'(b)(5935) ground-state baryons with spin-1/2 or the 1P or 2S excitation of the ground-state Xi(b)(5955) with spin-3/2. We calculate the masses of the possible angular-orbital 1P and 2S excited states corresponding to each channel employing the QCD sum rule technique. It is seen that all the obtained masses are in agreement with the experimentally observed value, implying that the mass calculations are not enough to determine the quantum numbers of the state under question. Therefore, we extend the analysis to investigate the possible decays of the excited states into Lambda K-b(0)- and Xi(-)(b) pi. Using the light cone QCD sum rule method, we calculate the corresponding strong coupling constants, which are used to extract the decay widths of the modes under consideration. Our results on decay widths indicate that the Xi(b)(6227)(-) is a 1P angular-orbital excited state of the Xi(b)(5955) baryon with quantum numbers J(P) = 3/2(-).
