2 results
Search Results
Now showing 1 - 2 of 2
Book Part Morphogenesis and Biomechanics of the Human Embryo and Fetus(Elsevier, 2020) Köse,S.; Baykal,B.; Korkusuz,F.; Korkusuz,P.Human embryo begins moving at tissue, cell and sub-cellular levels long before the mother emotionally feels the movement of the fetus. The human embryo and fetus not only develop in a mechanical environment but they exaggerate mechanical forces on themselves and their surroundings. Mechanical forces in example influence embryonic musculoskeletal development. In this chapter, the development and morphogenesis of human musculoskeletal system will be overviewed with their molecular aspects and the biomechanics of embryo and fetus will be discussed. © 2020 Elsevier Inc. All rights reserved.Book Part Citation - Scopus: 31Architecture of Bone Tissue and Its Adaptation To Pathological Conditions(Elsevier, 2020) Bilgiç,E.; Boyacıoğlu,Ö.; Gizer,M.; Korkusuz,P.; Korkusuz,F.Bone tissue is a mineralized and viscous-elastic connective tissue, which exerts crucial functions in our body such as support and protection of other tissues and mineral storage. Bone can adapt itself through a remodeling process, which is controlled by its cells, various local and systemic factors. It is a very complicated process composed of both cellular reactions and its effects on the internal structure of the bone. An imbalance between bone resorption and formation due to disease may alter its structure and mechanics. Mechanical properties of bone tissue are affected by different loading grades. Collagen material found in the extracellular matrix gives bone its elasticity. Bone is, nevertheless, a fragile structure depending on the loading and mineral content that also strengthens the bone. In this chapter, the structure of the bone in micro and macro scale, its mechanical properties in physiological circumstances and adaptation to pathological conditions will be discussed. © 2020 Elsevier Inc. All rights reserved.
