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Article On the Definition of Sequential Consistency(Elsevier Science Bv, 2005) Sezgin, A; Gopalakrishnan, GThe definition of sequential consistency is compared with an intuitive notion of correctness. That the definition is not strong enough is illustrated through a hypothetical memory system which is clearly incorrect, yet sequentially consistent. It is claimed that the reason for this is the absence of a relation between what actually happens (temporal order) and what seems to happen (logical order). A stronger version of sequential consistency is proposed. (c) 2005 Elsevier B.V. All rights reserved.Article Citation - WoS: 2Citation - Scopus: 4State-Based Conceptual Design in Mechatronics Via Petri Nets: a Case Study for an Educational Robot(Romanian Soc Control Tech informatics, 2011) Erden, Zuhal; Mechatronics EngineeringUse of state-based models to represent artifact behaviors at conceptual design is a challenging area for design research. Conceptual design of mechatronic systems needs a multi-domain approach in which the "logical behavior" of a mechatronic design artifact is described without any physical realization. This paper presents a case study on state-based representation for the intended behavior of a non-existent robot at early conceptual level. The behavior is defined through a demonstrative scenario and represented as states and state transitions independent of any physical embodiment. Discrete Event System Specification (DEVS) and Petri Net formalism are used for the model. This representational model is first step towards the development of a virtual prototype for the logical behavior of robot design.Article Citation - WoS: 3Citation - Scopus: 3Modeling and Measurement of Human Body Blockage Loss at 28 Ghz(Taylor & Francis Ltd, 2023) Benzaghta, Mohamed; Gokdogan, Bengisu Yalcinkaya; Coruk, Remziye Busra; Kara, AliMillimeter-wave (mm-Wave) spectrum is an essential enabler to the fifth generation (5G) wireless technology. Humans are one of the most noticeable blockers that cause temporal variation in indoor radio channels. This paper presents human blockage measurements at 28 GHz, with several humans of different sizes. The effect of the crossing orientations of the human bodies is investigated for three different transmitter heights. A human blockage model based on the Fresnel diffraction scheme is shown to be applicable in estimating the human blockage loss in indoor radio links considering various body sizes, different crossing orientations, and different transmitter heights. The findings reported in this paper could help improve indoor radio channel models at 28 GHz bands for 5G technologies considering the presence of human body blockages.Article Citation - WoS: 6Synthesis and Biological Study of Novel Indole-3 Derivatives as Src Kinase and Glutathione S-Transferase Inhibitors(Bentham Science Publ Ltd, 2013) Kurt, Z. Kilic; Aydin, D.; Isgor, Y. G.; Isgor, B. S.; Olgen, S.The aim of this study is to design and synthesize novel dual inhibitors of Src protein tyrosine kinase (PTK) and Glutathione S-transferases (GSTs), as a potential drug lead with therapeutic efficacy on cancer and immune disorders. The biological activity profiling of small molecule inhibitors via miniaturized biochemical techniques compatible with medium throughput screening and focused screening methodologies were performed. To determining the effects of small molecule inhibitors on Src kinase and Phase II detoxification enzyme GST isozymes in liver homogenates used to verify their roles in drug resistance mechanism for cancer chemotherapeutics. In this study, 14 indole-3-imine-2-on and N-benzyl indole-3-imine-2-on derivatives were synthesized for dual activities against Src and GST. The chemical structures and purities of compounds were verified by IR, H-1 NMR, MASS spectroscopy, and elemental analysis. The compounds 2, 3 and 9 are found slightly active against both enzyme Src and GST.Article On a Boundary Value Problem for a Class of Second-Order Complex Partial Differential Equations(Univ Simon Bolivar, 2023) Aksoy, Umit; Celebi, Ahmet OkayIn this article, a boundary value problem for a second-order complex partial differential equation whose main part is the Laplacian, is introduced and its solvability is discussed by reduction of the problem into the Schwarz problem for a first-order equation. The condition for solvability is presented and an estimate for the unique solution is provided.Article Citation - WoS: 2Citation - Scopus: 1Can Job Crafting Be a Remedy for Struggling With Work Alienation? the Moderator Effect of Perceived Supervisor Support*(Nomos verlagsgesellschaft Mbh & Co Kg, 2022) Aydin, Esra; Cinar, Esra; Basim, H. NejatDrawing on self-determination theory, this study focuses on the relationship between job crafting and work alienation and the moderating effect of perceived supervisor support. Based on theoretical discussions, this study examines (1) whether a negative relationship exists between job crafting and work alienation; (2) whether and how perceived supervisor support moderates that relationship. Findings are based on the data collected from a survey of 203 participants working in Turkey. The results indicate job crafting's negative association with work alienation. Perceived supervisor support is a moderating variable, fostering employee that, in turn, leads to reduced work alienation.Article Citation - WoS: 4Citation - Scopus: 6A Test Bench To Study Bioinspired Control for Robot Walking(Romanian Soc Control Tech informatics, 2011) Arikan, Kutluk B.; Irfanoglu, Bulent; Department of Mechatronics EngineeringTest bench to study robot walking within the predicted structures of biological control systems is discussed. Physical system is briefly presented with components. Kinematic model and evolutionary way of gait generation for the leg structure in test bench is discussed. Different forms of gaits can be found by genetic optimization using patterns formed by central pattern generators.Article Citation - WoS: 6Effectiveness of Proprioceptive Neuromuscular Facilitation and Myofascial Release Techniques in Patients With Subacromial Impingement Syndrome(Taylor & Francis Ltd, 2022) Celik, Merve Sinem; Sonmezer, Emel; Acar, ManolyaPurpose To compare the effectiveness of proprioceptive neuromuscular facilitation and myofascial release technique in patients with subacromial impingement syndrome on pain, range of motion, muscle strength, quality of life, functionality and disability. Methods Thirty patients were randomly divided into two groups: proprioceptive neuromuscular facilitation group (n = 15) and proprioceptive neuromuscular facilitation combined with myofascial release technique group (n = 15). Both treatment methods were performed 3 times a week for 4 weeks. Pain severity was assessed by Visuel Analog Scale, range of motion by a goniometer, muscle strength by digital hand dynamometer, quality of life by Nottingham health profile, functionality by arm, shoulder and hand problems questionnaire, disability by shoulder pain and disability index. All measurements were used before and after treatments. Pain severity, range of motion and muscle strength were also evaluated after the first session. Results After the treatment, shoulder pain, range of motion, muscle strength, functionality and disability were improved in two groups (p < 0.05). Proprioceptive neuromuscular facilitation showed improvement in pain, whereas myofascial release technique improved pain, physical activity, emotional state, sleep and total dimensions of life quality (p < 0.05). Proprioceptive neuromuscular facilitation was more effective in reducing activity pain, whereas myofascial release technique was more effective in increasing flexion, external and internal rotation range of motion, flexion and abduction muscle strength after the first session (p < 0.05). Conclusions The combined application of proprioceptive neuromuscular facilitation and myofascial release technique has a more acute and cumulative positive effect on pain, range of motion, muscle strength, functionality, disability and quality of life in patients with subacromial impingement syndrome.Article Citation - WoS: 12Citation - Scopus: 15Discrete Parameter-Nonlinear Constrained Optimisation of a Gear Train Using Genetic Algorithms(inderscience Enterprises Ltd, 2005) Dolen, M.; Kaplan, H.; Seireg, A.This paper investigates the optimal design of a four-stage gear train using genetic algorithms. Five different genetic encoding schemes, which incorporate various heuristic search techniques, are proposed to deal with the most critical constraints of the problem. The fitness criterion used by all genetic algorithms includes a merit function for minimising the size of the gearbox. The results show improvement in the design merit over previous approaches without reliance on the designer's interaction to avoid geometric constraint violations and facilitate the convergence.Article Toxoplasma gondii Coinfection in HIV-Positive Patients at a Tertiary Care Hospital(Bentham Science Publ Ltd, 2025) Kurkcu, Muhammed Furkan; Bakir, Ayfer; Kaba, Semiha Berra Topsakal; Kusabbi, Ilknur Alkan; Usluca, SelmaIntroduction: Toxoplasma gondii (T. gondii) can cause serious complications in both immunocompetent and immunosuppressed individuals. This study aims to assess the seroprevalence of T. gondii among HIV-positive individuals and to investigate its association with age, sex, CD4+ T cell count, HIV RNA levels, and hematological parameters. Methods: This study included 247 HIV-positive individuals followed up at a tertiary care hospital between November 1, 2022, and November 30, 2024. We analyzed serum samples for T. gondii IgG antibodies using electrochemiluminescent microparticle immunoassay. Results: The prevalence of T. gondii IgG seropositivity was found to be 32.8% (n=81; 95% CI: 26.9-39). The median age of seropositive individuals was 52 years (IQR: 42-61), which was significantly higher compared to seronegative individuals (p<0.001). The highest IgG seropositivity rate (66.7%) was observed in the 61-80 age group. Hemoglobin levels were significantly lower in IgG seropositive individuals (p=0.040). Logistic regression analysis indicated an increased risk of T. gondii infection with advancing age. The odds ratio for the 41-60 age group was 13.3 (95% CI: 1.6-106, p=0.02), while for the 61-80 age group, it was 28 (95% CI: 3.3-240, p=0.002). Discussion: The seroprevalence of T. gondii in HIV-positive individuals was lower than both global and regional averages. Age was identified as an independent risk factor for T. gondii seropositivity. Additionally, hematological alterations associated with anemia were observed in seropositive individuals. Further large-scale, multi-center, and regionally representative studies are required to optimize T. gondii infection management and screening strategies in people living with HIV. Conclusion: These findings suggest that T. gondii infection in HIV-positive individuals increases with age and may be associated with anemia, highlighting the need for age-focused screening and management strategies.
