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  • Article
    Citation - Scopus: 1
    An Investigation on the Dna Binding Activities of Melamine, Cyanuric Acid and Uric Acid
    (Editura Acad Romane, 2021) Senol, Ali; Devrim, Alparslan Kadir; Sudagidan, Mert; Ozalp, Veli Cengiz
    Melamine can be added to various foods such as milk, milk powder, baby food, pet, and livestock feed for cheating purposes due to its high nitrogen content. Regarding its usage in food products, there is a need to investigate its possible interactions with DNA. Thus, this study aimed to investigate the interactions of melamine and its metabolized products, cyanuric acid and uric acid with genomic DNA, isolated from eukaryotic (calf thymus) and prokaryotic (Staphylococcus aureus) sources. UV-absorbance spectrophotometry, fluorescence spectrophotometry, and agarose gel electrophoresis techniques were used to evaluate these interactions. The five different concentrations of melamine, cyanuric acid, and uric acid were incubated with fixed DNA concentration and it was determined that the test compounds interacted with the DNA molecules. The data obtained by UV-absorbance and fluorescence spectrophotometry techniques revealed an increase in wave peaks observed with the increasing substance concentration. After the obtained data of the aforementioned techniques were evaluated together, it was concluded that melamine, cyanuric acid, and uric acid bonded to the eukaryotic and prokaryotic genomic DNA materials via groove binding.
  • Article
    Citation - WoS: 6
    A Light Bulb in Every House the Istanbul General Electric Factory and American Technology Transfer To Turkey
    (Johns Hopkins Univ Press, 2022) Tunc, Tanfer Emin; Tunc, Gokhan
    In 1946, Turkish entrepreneur Vehbi Koc signed an agreement with the U.S. firm General Electric to build and operate its first light bulb factory in the Near/Middle East, in Istanbul. This private joint venture introduced new manufacturing techniques, business practices, and consumer habits to Turkey, opening channels of postwar technological exchange. Closer examination of the GE-Koc partnership reveals that during the early Cold War, the transfer and embedding of American technologies in Turkey was a politically complicated process of innovation that required constant adaptation. Fraught with unforeseeable obstacles, it also required cautious negotiation with multiple transnational actors. The story of the GE-Koc partnership thus adds a new dimension to historical understandings of the Turkish Cold War experience and the Americanization of the region. It illustrates how transferring a nonmilitary, soft-power, domestic technologythe light bulb-played a significant role in Turkish-American relations and therefore contributes to studies of U.S. Cold War diplomacy through transnational investment in innovation.
  • Article
    Citation - WoS: 1
    Citation - Scopus: 1
    The Effect of Group Behavior on the Pull-Out Capacity of Model Soil Nails in High Plasticity Clay
    (Springer int Publ Ag, 2024) Akis, Ebru; Bakir, Bahadir Sadik; Yilmaz, Mustafa Tolga
    Soil nailing technique is widely used in stabilizing roadway and tunnel portal cut excavations. The key parameter in the design of soil nail systems is the pull-out capacity. The pull-out capacity of soil nails can be estimated either from the studies involving similar soil conditions or from the empirical formulas available in the literature. Particularly, it has been documented placing nails closer than a certain minimum distance results in a reduction in the pull-out resistance of a nail placed in sand. However, this requirement has not been discussed for the nail groups located within clay formations. In order to investigate the influence of nail spacing on the pull-out resistance of nails, a series of laboratory pull-out experiments were performed in clay of high plasticity. The results of these experiments showed a remarkable trend. Specifically, there was a significant reduction in the pull-out capacity of a nail when the spacing between nails two times the nail diameter (2 & Oslash;). In contrast, the pull-out capacity of a nail embedded in clay remained unaffected by neighboring nails, provided the spacing was maintained at six times the nail diameter (6 & Oslash;). In addition, during the conducted pull-out tests, it was observed that the failure mode of a single nail and 6 & Oslash; spaced group nails near the surface results as heaving around the single nail. However, in the case of closely positioned (2 & Oslash; spaced) nails, the affected area following nail failure exhibits distinct characteristics, which operate as a group. This leads to the occurrence of failure in the form of heaving around the group of nails.
  • Article
    Investigating of Dynamic Compressive Response of Plain and Fiber-Reinforced Concrete Structures at Various Strain Rates
    (SAGE Publications Ltd, 2025) Gunay, A.R.; Hafizoglu, H.; Akdeniz, E.; Kaya, C.
    Across the world, studies on building design are conducted at various scales. The behavior of structures under static loading has been the subject of various studies in the modern era, leading to the development of significant standards and application techniques. However, studies on the behavior of structures under dynamic loading have remained limited. This study investigated the dynamic compressive behavior of plain and fiber-reinforced C60 and C80 concrete samples through experimental studies at room temperature. In addition, this study also investigated dynamic deformation and fracture behavior of plain concrete samples by numerical studies. For this purpose, plain and fiber-reinforced C60 and C80 concrete samples were produced. Experimental studies covered both static and dynamic compression tests. Following the static tests, dynamic test samples with a diameter and length of 10 mm were produced from the static test samples by water jet cutting method and were dynamically compressed in the Split Hopkinson Pressure Bar (SHPB) test setup. Dynamic compression test results showed that the strength of plain and fiber-reinforced C60 and C80 concretes were obtained in the range of 74–162 MPa at an average strain rate of between 139 and 650 s−1. Experimental results also showed that the fiber addition affected the dynamic increase factor (DIF) and impact toughness of both C60 and C80 concretes in a good manner. To compare experimental and numerical results, a dynamic compression test condition was visualized with a high-speed camera and simulated with the Ls-Dyna software using the finite-element method. Numerical studies indicated a good correlation with dynamic compression results in terms of crack formation and fracture progress. © IMechE 2025.
  • Article
    Citation - WoS: 1
    Exploring Supportive and Deterrent Factors on Online Shopping in a Developing Country
    (Igi Global, 2020) Pusatli, Tolga; Akman, Ibrahim
    This study explores the influence of the reasons of individuals' supportive and deterrent behaviors against commercial usage of online media in the emerging market of Turkey. The supportive and deterrent factors are grouped in empirical categories as discouragement and encouragement, respectively. The impact of these factors on actual behavior were assessed via intermediary empirical category including the variables inefficiency, efficiency, intention, and subjective norm. A survey was conducted using a sample of 251 observations obtained from the visitors of three large/busy malls using purposive sampling. The multiple least-square regression was utilized to test the nature of the relationships between variables. Results indicated a significant discouraging impact of warranty, finance, habits, security on inefficiency perceptions, an encouraging impact of geography and convenience on efficiency perceptions. Significant behavioral impact of perceptions regarding inefficiency, efficiency, subjective norms, and intention on actual usage of online shopping was also observed.
  • Book Part
    Clinical Development of Quinone-Based Drugs
    (Elsevier, 2024) Altuner, E.E.; Issa, G.; Ozalp, V.C.; Aldemir, O.; Torlak, Y.; Dar, U.A.
    This chapter provides a detailed explanation of the clinical investigations, pharmacological effects, and characteristics of quinone and quinone derivatives, along with references to pertinent sources. Although quinones have an oxygen group in their structure, they are quickly oxidized and interact with reactive oxygen species. This demonstrates how quinones work as drugs. Quinones and their derivatives are used as medications to treat a wide range of diseases, including cancer, lung, kidney, brain, and tumor disorders. Each of the following has effects on a different area of health; lapochols, anthraquinones, naphthoquinone and its derivatives, and other wide range of quinone derivatives are thoroughly explored in this chapter. © 2025 Elsevier Inc. All rights reserved.
  • Article
    Citation - WoS: 11
    Citation - Scopus: 20
    The Taylor Series Method and Trapezoidal Rule on Time Scales
    (Elsevier Science inc, 2020) Georgiev, Svetlin G.; Erhan, Inci M.
    The Taylor series method for initial value problems associated with dynamic equations of first order on time scales with delta differentiable graininess function is introduced. The trapezoidal rule for the same types of problems is derived and applied to specific examples. Numerical results are presented and discussed. (c) 2020 Elsevier Inc. All rights reserved.
  • Conference Object
    Citation - Scopus: 6
    The Use of Semi-Public Spaces as Urban Space and Evaluation in Terms of Urban Space Quality
    (Springer Nature, 2022) Orhan,M.
    The rapid physical change and increase in density of today’s cities lead to changes in urban space usage and habits in urban life. This change negatively affects the description and use of public spaces as socialisation spaces, which are one of the most significant urban components. As a result, city dwellers satisfy their need for public spaces with the use of different urban spaces. Urban life shifts from urban public spaces to semi-public spaces. Semi-public spaces are qualified and accessible spaces that ensure transition between private spaces (buildings) and public spaces. These spaces gain different attributes according to the characteristics (commerce, housing, tourism, etc.) of the urban spaces they coexist within and to the functions and designs of the structures surrounding them. These attributes determine their configuration as integrated or dissociated with the city and thus specify their relationship with the city. This relationship changes ‘city–space–structure–human’ interaction, and this change affects urban quality with the spatial quality of semi-public spaces. The aim of this study is to present how and related to which characteristics the use of semi-public spaces as urban spaces has changed, to detect the effects of this change on the urban environment and to establish the role of semi-public spaces in terms of urban quality. In conclusion, semi-public spaces with different characteristics located in different urban spaces will be examined as regards physical, schematic, functional characteristics and use within the scope of this study. In accordance with the data obtained by comparative analysis method, approaches to facilitate their use as urban spaces and to ensure their integration with the city will be introduced. Accordingly, criteria that semi-public spaces should possess in order to increase and sustain urban space quality will be determined. © 2022, The Author(s), under exclusive license to Springer Nature Switzerland AG.
  • Letter
    Medical Education During the Covid-19 Pandemic: Experience From a Newly Established Medical School
    (Springer india, 2020) Tulek, Necla; Gonullu, Ugur
    [No Abstract Available]
  • Article
    Citation - WoS: 11
    Citation - Scopus: 15
    A Study on the Performance Evaluation of Wavelet Decomposition in Transient-Based Radio Frequency Fingerprinting of Bluetooth Devices
    (Wiley, 2022) Almashaqbeh, Hemam; Dalveren, Yaser; Kara, Ali
    Radio frequency fingerprinting (RFF) is used as a physical-layer security method to provide security in wireless networks. Basically, it exploits the distinctive features (fingerprints) extracted from the physical waveforms emitted from radio devices in the network. One of the major challenges in RFF is to create robust features forming the fingerprints of radio devices. Here, dual-tree complex wavelet transform (DT-CWT) provides an accurate way of extracting those robust features. However, its performance on the RFF of Bluetooth transients which fall into narrowband signaling has not been reported yet. Therefore, this study examines the performance of DT-CWT features on the use of transient-based RFF of Bluetooth devices. Initially, experimentally collected Bluetooth transients from different smartphones are decomposed by DT-CWT. Then, the characteristics and statistics of the wavelet domain signal are exploited to create robust features. Next, the support vector machine (SVM) is used to classify the smartphones. The classification accuracy is demonstrated by varying channel signal-to-noise ratio (SNR) and the size of transient duration. Results show that reasonable accuracy can be achieved (lower bound of 88%) even with short transient duration (1024 samples) at low SNRs (0-5 dB).