TR-Dizin
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Article Citation - WoS: 4Citation - Scopus: 516s Bacterial Metagenomic Analysis of Herby Cheese (otlu Peynir) Microbiota(Istanbul Univ-cerrahpasa, 2021) Sudağıdan, Mert; Yurt, Mediha Nur Zafer; Taşbaşı, Behiye Büşra; Acar, Elif Esma; Ömeroğlu, Esra Ersoy; Uçak, Samet; Aydın, AliCheese microbiota may contain various bacterial species due to the use of different types of milk, rennet, and herbs. In this study, the distribution of the dominant bacteria present in the microbiota of herby cheese samples (n = 13) were examined by the next generation sequencing (NGS) technique. DNA was extracted both directly from cheese samples and after pre-enrichment. The metagenomic analysis of the NGS results revealed that Firmicutes were dominant both in DNA directly extracted from herby cheese (KOP), and pre-enriched samples (OP), at the phylum level. At the genus level, Lactobacillus, Lactococcus, and Streptococcus were dominant in the KOP samples, whereas in the OP samples, Enterococcus, Streptococcus, and Bacillus were determined as the dominant bacterial genera. Although Lactococcus raffinolactis and Streptococcus salivarius were dominant in the KOP samples, Enterococcus faecalis and S. salivarius were dominant in the OP samples. The Shannon species diversity index and principal coordinates analysis (PCoA) were used to determine the distribution in KOP and OP samples at the genus level. The PCoA of KOP-10, KOP-11, KOP-2, and KOP-7, KOP-3, and KOP-6 samples showed the wide distribution, whereas KOP-5, KOP-8, KOP-9, and KOP-14 herby cheese samples were closely related. The OP samples, especially OP-7 and OP-14, showed wide distribution in comparison to other OP samples. Finally, the dominant bacterial communities were identified by DNAbased metagenomic analysis, and this is the first report to elucidate the microbiota of herby cheese produced in Turkey using the NGS technique.Review Citation - WoS: 3Citation - Scopus: 4Akciğer Kanserinde İmmünoterapi ve Tedavide Multidisipliner Yaklaşım(Turkish Assoc Tuberculosis & Thorax, 2020) Karadurmuş, Nuri; Kaya, Akın; Göksel, Tuncay; Yılmaz, Ülkü; Tülek, NeclaAkciğer kanseri dünya genelinde kanserle ilişkili ölümlerin başlıca nedeniolmaya devam etmektedir. Son 20 yılda kanser biyolojisi ve patogenezi hakkındaki bilgiler artmış, immün kontrol noktası inhibitörleri (İKNİ) kullanımasunulmuş ve böylece solid kanserlerin tedavisinde önemli bir dönem başlamıştır. Bu derlemede; tedavide yenilikler, immünoterapi ve tedavide multidisipliner yaklaşım çerçevesinde akciğer kanseri ele alınmıştır. Küçük hücreli dışıakciğer kanseri (KHDAK) en sık görülen ve özellikleri nedeniyle İKNİ tedavisinden ideal olarak yararlanabilecek akciğer kanseri türü olması nedeniyleyazının odak noktasını oluşturmuştur. Bu derleme, akciğer kanseri tedavisindeimmünoterapi yaklaşımının göğüs hastalıkları başta olmak üzere tüm branşlarda multidisipliner farkındalığını artırmayı ve yönetimi hakkında bilgi sağlamayıamaçlayan ilk Türkçe derlemedir. Ayrıca bu derleme, KHDAK tedavisinde İKNİkullanımına ilişkin son klinik çalışmaların dikkat çekici sonuçlarını sunmasıaçısından önem teşkil etmektedir. İmmünoterapi kanser tedavisinde yeni bir dönem başlatmıştır ve İKNİ tedavisinin kendine özgü etki mekanizması yeni bazı advers olay grubunun ortaya çıkmasına nedenolmuştur, bunlar arasında pnömonitis özellikle önemlidir ve advers olaylar konusunda gerektiğinde hastaların ilgili uzmanlık dalları ilekonsülte edilmesi gerekmektedir. Akciğer kanserinde tedavi, hastanın özellikleri, histolojik özellikler, genetik durum göz önünde bulundurularak her bir hastaya özel planlanmalı ve akciğer kanserli bir hastanın tanısal değerlendirilmesi ve en uygun şekilde tedavisi içingöğüs hastalıkları, göğüs cerrahisi, tıbbi onkoloji, radyasyon onkolojisi, patoloji ve radyoloji uzmanlık dalları arasında işbirliği sağlanmalıdır. Bununla birlikte, aile hekimleri de akciğer kanserinin erken tanınmasında ve ayrıca hastalarını tütün bırakmayı teşvik ederekkanserin önlenmesinde önemli rol oynayabilirler. Ayrıca, toplumda farkındalık yaratmak ve erken tanı için akciğer kanseri yönündentarama çalışmaları yapmak hedeflenmelidirArticle Citation - WoS: 7Citation - Scopus: 10Ann-Assisted Forecasting of Adsorption Efficiency To Remove Heavy Metals(Tubitak Scientific & Technological Research Council Turkey, 2019) Buaısha, Magdi; Balku, Şaziye; Yaman, Şeniz ÖzalpIn wastewater treatment, scientific and practical models utilizing numerical computational techniques suchas artificial neural networks (ANNs) can significantly help to improve the process as a whole through adsorption systems.In the modeling of the adsorption efficiency for heavy metals from wastewater, some kinetic models have been used such as pseudo first-order and second-order. The present work develops an ANN model to forecast the adsorption efficiency of heavy metals such as zinc, nickel, and copper by extracting experimental data from three case studies. To do this, we apply trial-and-error to find the most ideal ANN settings, the efficiency of which is determined by mean square error (MSE) and coefficient of determination (R2). According to the results, the model can forecast adsorption efficiency percent (AE%) with a tangent sigmoid transfer function (tansig) in the hidden layer with 10 neurons and a linear transferfunction (purelin) in the output layer. Furthermore, the Levenberg–Marquardt algorithm is seen to be most ideal for training the algorithm for the case studies, with the lowest MSE and high R2 . In addition, the experimental results and the results predicted by the model with the ANN were found to be highly compatible with each other.Article Citation - WoS: 1Citation - Scopus: 1Anticipatory Effect of Execution on Observation: an Approach Using Exopinch Finger Robot(Tubitak Scientific & Technological Research Council Turkey, 2019) Arıkan, Kutluk Bilge; Zadeh, Hassan Gol Mohammad; Turgut, Ali Emre; Zinnuroğlu, Murat; Bayer, Gözde; Günendi, Zafer; Cengiz, BülentBackground/aim: This study aims to explore the mirror neuron system (MNS) involvement using mu (8–12 Hz)/beta (15–25 Hz) bandsuppression in an action observation-execution paradigm.Materials and methods: Electrophysiological (EEG) data from 16 electrodes were recorded while 8 participants observed video clips ofa hand squeezing a spring. Specifically, the effect of anticipated execution on observation was studied. For this purpose, a fully actuatedfinger exoskeleton robot was utilized to synchronize observation and execution and to control the execution condition for the participants. Anticipatory effect was created with a randomized robot accompany session.Results: The results showed that the observational condition (with or without anticipation) interacted with hemisphere at central channels near somatosensory cortex. Additionally, we explored the response of MNS on the kinetics features of visual stimuli (hard or softspring).Conclusion: The results showed an interaction effect of kinetics features and hemisphere at frontal channels corresponding nearly tothe ventral premotor cortex area of the brain. The activation of mirror neurons in this area plays a crucial role in observational learning.Based on our results, we propose that specific type of visual stimuli can be combined with the functional abilities of the MNS in the action observation based treatment of hand motor dysfunction of stroke patients to have a positive additional impact.Article Citation - Scopus: 2An Approach for Performance Prediction of Saturated Brushed Permanent Magnet\rdirect Current (dc) Motor From Physical Dimensions(Tubitak Scientific & Technological Research Council Turkey, 2022) Asl, Rasul Tarvirdilu; Zeinali, Reza; Ertan, Hulusi BulentAn analytical approach for performance prediction of saturated brushed permanent magnet direct current\r(DC) motors is proposed in this paper. In case of a heavy saturation in the stator back core of electrical machines, some\rflux completes its path through the surrounding air, and the conventional equivalent circuit cannot be used anymore.\rThis issue has not been addressed in the literature. The importance of considering the effect of the flux penetrating\rthe surrounding air is shown in this paper using finite element simulations and experimental results, and an analytical\rapproach is proposed to consider this effect on magnet operating point determination and performance prediction of\rsaturated brushed permanent magnet DC motors. An analytical method is also presented to determine the boundary\rradius of the surrounding air for obtaining accurate results in finite element (FE) solutions and analytical calculations.\rAn analytical approach based on Carter’s coefficient is also proposed to calculate the effective length of the magnet when\rthe length of the magnet and rotor length are not the same. The accuracy of the proposed analytical model is illustrated\rusing finite element simulations and experimental results. With this accuracy, this analytical model is very suitable to\rbe used for reliable and quick mathematical design optimization.Article Citation - WoS: 13Citation - Scopus: 13Association between monocyte to high-density lipoprotein cholesterol ratio and bicuspid\raortic valve degeneration(Tubitak Scientific & Technological Research Council Turkey, 2020) Karaduman, Bilge Duran; Ayhan, Hüseyin; Keles, Telat; Bozkurt, EnginBackground/aim: From a pathophysiological point of view, inflammation is thought to be more dominant in bicuspid aortic valve\r(BAV) stenosis than tricuspid aortic valve (TAV) stenosis. Our study aimed to determine the association between monocyte to highdensity lipoprotein cholesterol (HDL-C) ratio (MHR), a new inflammatory marker, and the speed of progression of stenosis and\rpathophysiology of BAV stenosis.\rMaterials and methods: A total of 210 severe aortic stenosis patients (70 consecutive BAV patients, 140 matched TAV patients) were\rretrospectively enrolled in the study. Clinical and echocardiographic data and laboratory results related to our research were collected\rretrospectively from the patients’ records. MHR was measured as the ratio of the absolute monocyte count to the HDL-C value.\rResults: Seventy BAV (mean age: 72.0 ± 9.1 years, 42.9% female) and 140 TAV patients (mean age: 77.9 ± 8.3 years, 51.4% female)\rwith severe aortic stenosis were enrolled in this study. There was no difference between the two groups in terms of another baseline\rdemographic or clinic findings except age (P < 0.001). Monocyte count, hemoglobin level, mean platelet volume was significantly\rhigher, and HDL-C level was significantly lower in the BAV group, while other lipid and CBC parameters were found to be similar. In\rthe multivariate analysis, MHR (P = 0.005, 95% CI: 0.90–0.98) and, as expected, age (P = 0.001, 95% CI: 1.02–1.11) were found to be\rsignificant as the independent predictor of BAV, after adjusting for other risk factors.\rConclusion: Our study showed a significant correlation between increased MHR and BAV. MHR was determined as a significant\rindependent predictor for the speed of progression and diagnosis of severe BAV stenosis in multivariate analysis.Article Citation - WoS: 11Citation - Scopus: 15Biomaterials and Tissue Engineering for Regenerative Repair of Articular Cartilage Defects(Turkish League Against Rheumatism, 2009) Tur, Kazim; Department of Metallurgical and Materials EngineeringArticular cartilage defects heal very poorly and lead to degenerative arthritis. Existing medications cannot promote healing process; cartilage defects eventually require surgical replacements with autografts. As there is not enough source of articular cartilage that can be donated for autografting, materials that promote cartilage regeneration are important in both research and clinical applications. Tissue engineering involves cell growth on biomaterial scaffolds in vitro. These cells are then injected into cartilage defects for biological in vivo regeneration of the cartilage tissue. This review aims first to provide a brief introduction to the types of materials in medicine (biomaterials), to their roles in treatment of diseases, and to design factors and general requirements of biomaterials. Then, it attempts to sum up the recent advances in engineering articular cartilage; one of the most challenging area of study in biomaterials based tissue engineering, as an example to the research on regenerative solutions to musculoskeletal problems with an emphasis on the biomaterials that have been developed as scaffolds for cartilage tissue engineering. The definitive goal on cartilage regeneration is to develop a system using biomimetic approach to produce cartilage tissue that mimics native tissue properties, provides rapid restoration of tissue function, and is clinically translatable. This is obviously an ambitious goal; however, significant progress have been made in recent years; and further advances in materials design and technology will pave the way for creating significantly custom-made cellular environment for cartilage regeneration. (Turk J Rheumatol 2009; 24: 206-17)Article Borulu Sulama Şebekeleri Optimizasyonu(Turkish Chamber Civil Engineers, 2018) Marım, Gökhan; Darama, Yakup; Bozkuş, ZaferBorulu sulama şebekeleri ülkelerin tarımsal ürün yetiştirmesinde ve su tasarrufunda enönemli sistemlerdir. Günümüzde tarımsal amaçlı sulama, su tüketiminin en yüksek olduğusektördür. Ülkemizde tarım sektörünün kullandığı su miktarı su potansiyelimizin %73oranındadır. Ülkemizde ve genelde Dünyada nüfus artışı nedeniyle tarımsal üretimde sutalebinin artması ve su kaynaklarımızın sınırlı olması nedeniyle sürdürülebilir su kaynaklarıyönetimi zorunlu olmaktadır. Son yıllarda ülkemizde yapılan sulama sistemleri yatırımlarınınbüyük bir çoğunluğunu, su kaybını ve tarımsal su kullanımını azaltan modern borulu sulamaşebekeleri yatırımları oluşturmaktadır. Bu çalışma borulu sulama şebekelerinintasarımlarının maliyet ve istenen işletme basınçları açısından optimum koşullara ulaşmasınaodaklanmıştır. Optimizasyon problemi çözümünde heuristik tabanlı dinamik programlamaile birlikte doğrusal programlama yöntemi olan “Simplex” metodu kullanılmış olup, buoptimizasyon yazılımı DSİ borulu sulama şebekeleri için uygulanmıştır.Article Citation - WoS: 1Citation - Scopus: 1Bozucu Torklar Altında İzdüşümsel Doğru Akım Motoru Kontrolü(Gazi Univ, Fac Engineering Architecture, 2018) Doruk, Reşat Özgür; Zuglam, İsmailBu çalışmada, izdüşümsel doğrusal kareselservo geri beslemesi (P-LQSF) yöntemiyle tasarlanmış bir birdoğru akım (DC) motoru denetim yaklaşımı sunulmaktadır. Tasarlanan denetleyicinin kararlılığı girdidenhale-kararlılıkyaklaşımından yola çıkarak incelenmektedir. İzdüşümsel kontrol yöntemi, tam durumdeğişkeni geri beslemeli bir denetleyicinin özdeğer spektrumunu çıktı geri beslemesi kullanarak yaklaşıkolarak elde etmeyi amaçlar. Tasarlanan denetleyicilerin kararlılık analizi hem teorik hem de sayısalbenzetim yoluyla incelenecektir. Temel doğrusal kararlılığın yanı sıra, bozucu etkilerin kapalı döngüyü birdış girdi olarak etkilemesinden yola çıkarak girdiden-çıktıya-kararlılık kavramından yararlanılması olanaklıolabilmektedir. Sonuç olarak bir bozucu etkiden-hale-kararlılık yaklaşımı ortaya çıkmaktadır. Tasarımlar,elde edilen bu yaklaşımla incelenecektir. Performanslar ise sayısal benzetimler yoluyla görülecektir.Article Citation - WoS: 11Citation - Scopus: 14Card Spending Dynamics in Turkey During the Covid-19 Pandemic(Central Bank Republic Turkey, 2021) Kantur, Zeynep; Özcan, GülserimThis paper provides an extensive analysis of card spending during the COVID-19 pandemic in Turkey by using weekly aggregated and sectoral credit and debit card spending data from March 2014 to December 2020. At an aggregated level, we show that aggregate demand decreases significantly at the early stages of COVID-19 and seems to reinstate its pre-COVID trend. However, when we include the pre-existing conditions of Turkey, the 2018 currency crisis, we observe that the recovery in demand is not that strong. To highlight the underlying reasons for structural change in aggregate demand, we estimate the model with stringency index and unemployment-related search index. The estimated model indicates that containment measures and restrictions and fear of job/income loss mainly explain the overall impact of COVID-19 on aggregate demand. We also examined sectoral data to understand aggregate demand dynamics better. Only stable and delayable sector groups have reached a trend above their pre-pandemic trajectories. However, the social and work-related sectors are far from their respective pre-pandemic trend.Article Citation - WoS: 2Caval Valve Implantation Procedure in 7 Cases of Torrential Tricuspid Regurgitation and Step-By Description of the Procedure(Kare Publ, 2025) Sarıçam, Ersin; Barcin, Cem; Çelebi, Aksüyek Savaş; Asfour, Mohamed; Bozbas, Huseyin; İlkay, ErdoğanArticle Citation - WoS: 3Citation - Scopus: 3Characterization of Mesenchymal Stem Cells in Mucolipidosis Type Ii (i-Cell Disease)(Tubitak Scientific & Technological Research Council Turkey, 2019) Köse, Sevil; Kaya, Fatima Aerts; Kuşkonmaz, Bülent Barış; Çetinkaya, Duygu UçkanMucolipidosis type II (ML-II, I-cell disease) is a fatal inherited lysosomal storage disease caused by a deficiency of theenzyme N-acetylglucosamine-1-phosphotransferase. A characteristic skeletal phenotype is one of the many clinical manifestationsof ML-II. Since the mechanisms underlying these skeletal defects in ML-II are not completely understood, we hypothesized that adefect in osteogenic differentiation of ML-II bone marrow mesenchymal stem cells (BM-MSCs) might be responsible for this skeletalphenotype. Here, we assessed and characterized the cellular phenotype of BM-MSCs from a ML-II patient before (BBMT) and afterBM transplantation (ABMT), and we compared the results with BM-MSCs from a carrier and a healthy donor. Morphologically, wedid not observe differences in ML-II BBMT and ABMT or carrier MSCs in terms of size or granularity. Osteogenic differentiation wasnot markedly affected by disease or carrier status. Adipogenic differentiation was increased in BBMT ML-II MSCs, but chondrogenicdifferentiation was decreased in both BBMT and ABMT ML-II MSCs. Immunophenotypically no significant differences were observedbetween the samples. Interestingly, the proliferative capacity of BBMT and ABMT ML-II MSCs was increased in comparison to MSCsfrom age-matched healthy donors. These data suggest that MSCs are not likely to cause the skeletal phenotype observed in ML-II, butthey may contribute to the pathogenesis of ML-II as a result of lysosomal storage-induced pathology.Article Citation - WoS: 1Citation - Scopus: 3The Clinical and Demographical Characteristics of Turkish Pediatric Lymphedema Patients: a Multicenter Study(Tubitak Scientific & Technological Research Council Turkey, 2022) Borman, Pinar; Balcan, Aysegul; Eyigor, Sibel; Coskun, Evrim; Ayhan, Figen; Cakit, Burcu Duyur; Dogan, Sevil CeyhanBackground/aim: Reducing lymphedema-associated burden and disability in the pediatric setting requires improved awareness and understanding clinical properties of the lymphedema. The aim of this study was to evaluate the clinical and demographic characteristics of patients with pediatric lymphedema presented to different lymphedema centers in Turkey. Materials and methods: The socio-demographic and clinical characteristics of the children including age, gender, presence of genetic syndromes, duration of edema, site and stage of lymphedema and the received therapies were determined. Parental and children education on self-management techniques were recorded. Results: A total of 122 children (female: 66, male: 56) with a mean age of 120.7 +/- 71.2 months were included from 7 centers. Of them; 92% had primary, 8% had secondary lymphedema mostly due to infection and trauma. Lymphedema was part of a syndrome in 18% of the children. The most common site of involvement was the lower extremity, followed by upper extremity and genital involvement. Lymphedema was complicated in 17 % of children, mainly with a clinical picture of cellulitis, infection, and pain. The median duration of lymphedema was 41 (5-216) months. Although most of the children had stage 2 lymphedema, only 40% of them received treatment. The most commonly received treatment was compression therapy. No family or child was educated for self-care management before. Conclusion: In conclusion, pediatric lymphedema has a comparable gender distribution and usually involves the lower extremities. Although most of the children had advanced disease, more than half of the patients did not receive any treatment indicating the unmet need for management of lymphedema. The education of patients and/or children about self-management methods were lacking. We suggest educational activities for both families of children with lymphedema and health care providers, in order to facilitate early reference to lymphedema units and to receive prompt preventive and therapeutic approaches for this suffering condition.Article Citation - WoS: 2Citation - Scopus: 3The Clinical, Functional, and Radiological Features of Hand Osteoarthritis: Tlar-Osteoarthritis Multi-Center Cohort Study(Turkish League Against Rheumatism, 2022) Duruoz, Mehmet Tuncay; Gursoy, Didem Erdem; Tuncer, Tiraje; Altan, Lale; Ayhan, Figen; Bal, Ajda; Ugurlu, HaticeObjectives: This study aims to evaluate the clinical, functional, and radiological features of hand osteoarthritis (OA) and to examine their relationships in different geographic samples of the Turkish population. Patients and methods: Between April 2017 and January 2019, a total of 520 patients (49 males, 471 females; mean age: 63.6 +/- 9.8 years) with hand OA were included in the study from 26 centers across Turkiye by the Turkish League Against Rheumatism (TLAR). The demographic characteristics, grip strengths with Jamar dynamometer, duration of hand pain (month), the severity of hand pain (Visual Analog Scale [ VAS]), and morning stiffness were evaluated. The functional disability was evaluated with Duruoz Hand Index (DHI). The Kellgren-Lawrence (KL) OA scoring system was used to assess the radiological stage of hand OA. Results: The DHI had significant correlations with VAS- pain (r= 0.367, p<0.001), duration of pain (r=0.143, p=0.001) and bilateral handgrip strengths (r=-0.228, p=0.001; r=-0.303, p<0.001). Although DHI scores were similar between the groups in terms of the presence of hand deformity (p= 0.125) or Heberden's nodes (p=0.640), the mean DHI scores were significantly higher in patients with Bouchard's nodes (p=0.015). The total number of nodes had no significant correlations with the VAS-pain and DHI score (p>0.05). The differences between the groups of radiological hand OA grades in terms of age (p= 0.007), VAS-pain (p<0.001), duration of pain (p<0.001), and DHI (p<0.001) were significant. There were no significant differences between radiological hand OA grades according to the duration of the stiffness, grip strength, and BMI (p>0.05 for all). Conclusion: In our population, the patients with hand OA had pain, functional disability, and weak grip strength. The functional impairment was significantly correlated with the severity of the pain, and the functional status was worse in high radiological hand OA grades.Article Citation - WoS: 16Citation - Scopus: 20Common Fixed Point Theorems in Cone Banach Spaces(Hacettepe Univ, Fac Sci, 2011) Abdeljawad, Thabet; Karapinar, Erdal; Tas, Kenan; MathematicsRecently, E. Karapinar (Fixed Point Theorems in Cone Banach Spaces, Fixed Point Theory Applications, Article ID 609281, 9 pages, 2009) presented some fixed point theorems for self-mappings satisfying certain contraction principles on a cone Banach space. Here we will give some generalizations of this theorem.Article Citation - Scopus: 21Comparative Analysis of Programming Languages Utilized in Artificial Intelligence Applications: Features, Performance, and Suitability(Prof.Dr. İskender AKKURT, 2024) Sezen, Arda; Türkmen, Güzin; Şengül, GökhanThis study presents a detailed comparative analysis of the foremost programming languages employed in Artificial Intelligence (AI) applications: Python, R, Java, and Julia. These languages are analysed for their performance, features, ease of use, scalability, library support, and their applicability to various AI tasks such as machine learning, data analysis, and scientific computing. Each language is evaluated based on syntax and readability, execution speed, library ecosystem, and integration with external tools. The analysis incorporates a use case of code writing for a linear regression task. The aim of this research is to guide AI practitioners, researchers, and developers in choosing the most appropriate programming language for their specific needs, optimizing both the development process and the performance of AI applications. The findings also highlight the ongoing evolution and community support for these languages, influencing long-term sustainability and adaptability in the rapidly advancing field of AI. This comparative assessment contributes to a deeper understanding of how programming languages can enhance or constrain the development and implementation of AI technologies.Article Citation - WoS: 7Citation - Scopus: 10Comparison of Three Different Learning Methods of Multilayer Perceptron Neural Network for Wind Speed Forecasting(Gazi Univ, 2021) Bulut, Mehmet; Tora, Hakan; Buaisha, Dr.magdiIn the world, electric power is the highest need for high prosperity and comfortable living standards. The security of energy supply is an essential concept in national energy management. Therefore, ensuring the security of electricity supply requires accurate estimates of electricity demand. The share of electricity generation from renewables is significantly growing in the world. This kind of energy types are dependent on weather conditions as the wind and solar energies. There are two vital requirements to locate and measure specific systems to utilize wind power: modelling and forecasting of the wind velocity. To this end, using only 4 years of measured meteorological data, the present research attempts to estimate the related speed of wind within the Libyan Mediterranean coast with the help of ANN (artificial neural networking) with three different learning algorithms, which are Levenberg-Marquardt, Bayesian Regularization and Scaled Conjugate Gradient. Conclusions reached in this study show that wind speed can be estimated within acceptable limits using a limited set of meteorological data. In the results obtained, it was seen that the SCG algorithm gave better results in tests in this study with less data.Article Citation - WoS: 4Citation - Scopus: 5Construction of a Complex Jacobi Matrix From Two-Spectra(Hacettepe Univ, Fac Sci, 2011) Guseinov, Gusein Sh; MathematicsIn this paper we study the inverse spectral problem for two-spectra of finite order complex Jacobi matrices (tri-diagonal matrices). The problem is to reconstruct the matrix using two sets of eigenvalues, one for the original Jacobi matrix and one for the matrix obtained by deleting the first column and the first row of the Jacobi matrix. An explicit procedure of reconstruction of the matrix from the two-spectra is given.Article Citation - WoS: 1Citation - Scopus: 2A Convergent Two-Level Linear Scheme for the Generalized Rosenau–kdv–rlw Equation(Tubitak Scientific & Technological Research Council Turkey, 2019) Aydın, AyhanA new convergent two-level finite difference scheme is proposed for the numerical solution of initial valueproblem of the generalized Rosenau–KdV–RLW equation. The new scheme is second-order, linear, conservative, andunconditionally stable. It contains one free parameter. The impact of the parameter to error of the numerical solutionis studied. The prior estimate of the finite difference solution is obtained. The existence, uniqueness, and convergence ofthe scheme are proved by the discrete energy method. Accuracy and reliability of the scheme are tested by simulating thesolitary wave graph of the equation. Wave generation subject to initial Gaussian condition has been studied numerically.Different wave generations are observed depending on the dispersion coefficients and the nonlinear advection term.Numerical experiments indicate that the present scheme is conservative, efficient, and of high accuracy, and well simulatesthe solitary waves for a long time.Article Correlation of Clinical Signs and Magnetic Resonance Imaging Findings in Patients With Lumbar Spondylosis(Turkish League Against Rheumatism, 2023) Altan, Lale; Ökmen, Burcu Metin; Tuncer, Tiraje; Sindel, Dilşad; Çay, Hasan Fatih; Hepgüler, Simin; Uğurlu, HaticeObjectives: The purpose of the study was to contribute further to this debated topic by investigating the correlation of magnetic resonance imaging (MRI) findings with the clinical picture in lumbar spondylosis patients. Patients and methods: This multicenter retrospective study (as part of the epidemiological project of the TLAR-OASG [Turkish League Against Rheumatism-Osteoarthritis Study Group]) included 514 patients (101 males, 413 females; mean age: 63.6±10.8 years; range, 40 to 85 years) who were diagnosed as lumbar spondylosis by clinical examination and direct X-ray between December 2016 and June 2018. Demographic characteristics of patients, Visual Analog Scale for pain, presence of radiating pain, Roland-Morris disability questionnaire, straight leg raise test, deep tendon reflexes, neurogenic intermittent claudication symptoms, any decrease of muscle strength, and abnormality of sensation were recorded. Lumbar MRI findings of the patients were recorded as positive or negative in terms of disc herniation, intervertebral disc degeneration, root compression, osteophytes, spinal stenosis. Statistical analysis was done to assess the correlation between the clinical symptoms, physical examination, and MRI findings. Results: Correlation analysis of the MRI results and the clinical findings showed a significant correlation between straight leg raise test and root compression (p<0.001, r=0.328) and a significant correlation between neurogenic intermittent claudication and spinal stenosis (p<0.001, r=0.376). Roland-Morris disability questionnaire had a significant correlation with all MRI findings (p<0.05, r<0.200). Conclusion: The results of this study corroborate the notion that diligent patient history and physical examination are more valuable than MRI findings, even though a higher incidence of abnormal MRI findings have been obtained in patients with disability and dermatomal radiating pain.

