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  • Article
    Citation - WoS: 3
    Citation - Scopus: 3
    Detection of spermatogonial stem/progenitor cells in prepubertal mouse testis with deep learning
    (Springer/plenum Publishers, 2023) Kahveci, Burak; Onen, Selin; Akal, Fuat; Korkusuz, Petek
    PurposeRapid and easy detection of spermatogonial stem/progenitor cells (SSPCs) is crucial for clinicians dealing with male infertility caused by prepubertal testicular damage. Deep learning (DL) methods may offer visual tools for tracking SSPCs on testicular strips of prepubertal animal models. The purpose of this study is to detect and count the seminiferous tubules and SSPCs in newborn mouse testis sections using a DL method.MethodsTesticular sections of the C57BL/6-type newborn mice were obtained and enumerated. Odd-numbered sections were stained with hematoxylin and eosin (H&E), and even-numbered sections were immune labeled (IL) with SSPC specific marker, SALL4. Seminiferous tubule and SSPC datasets were created using odd-numbered sections. SALL4-labeled sections were used as positive control. The YOLO object detection model based on DL was used to detect seminiferous tubules and stem cells.ResultsTest scores of the DL model in seminiferous tubules were obtained as 0.98 mAP, 0.93 precision, 0.96 recall, and 0.94 f1-score. The SSPC test scores were obtained as 0.88 mAP, 0.80 precision, 0.93 recall, and 0.82 f1-score.ConclusionSeminiferous tubules and SSPCs on prepubertal testicles were detected with a high sensitivity by preventing human-induced errors. Thus, the first step was taken for a system that automates the detection and counting process of these cells in the infertility clinic.
  • Review
    Citation - WoS: 2
    Citation - Scopus: 5
    Machine Learning for Sustainable Reutilization of Waste Materials as Energy Sources - a Comprehensive Review
    (Taylor & Francis inc, 2024) Peng, Wei; Sadaghiani, Omid Karimi
    This work reviews Machine Learning applications in the sustainable utilization of waste materials as energy source so that analysis of the past works exposed the lack of reviewing study. To solve it, the origin of waste biomass raw materials is explained, and the application of Machine Learning in this section is scrutinized. After analysis of numerous papers, it is concluded that Machine Learning and Deep Learning are widely utilized in waste biomass production areas to enhance the quality and quantity of production, improve the predictions, diminish the losses, as well as increase storage and transformation conditions. The positive effects and application with the utilized algorithms and other effective information are collected in this work for the first time. According to the statistical analysis, in 20% out of the studies conducted about the application of Machine Learning and Deep Learning in waste biomass raw materials, Artificial Neural Network (ANN) algorithm has been applied. Afterward, the Super Vector Machine (SVM) and Random Forest (RF) are the second and third most-utilized algorithms applied in 15% and 14% of studies. Meanwhile, 27% of studies focused on the applications of Machine Learning and Deep Learning in the Forest wastes.
  • Review
    Citation - WoS: 3
    Citation - Scopus: 5
    A Systematic Review on Smart Waste Biomass Production Using Machine Learning and Deep Learning
    (Springer, 2023) Peng, Wei; Sadaghiani, Omid Karimi
    The utilization of waste materials, as an energy resources, requires four main steps of production, pre-treatment, bio-refinery, and upgrading. This work reviews Machine Learning applications in the waste biomass production step. By investigating numerous related works, it is concluded that there is a considerable reviewing gap in the surveying and collecting the applications of Machine Learning in the waste biomass. To fill this gap with the current work, the kinds and resources of waste biomass as well as the role of Machine Learning and Deep Learning in their development are reviewed. Moreover, the storage and transportation of the wastes are surveyed followed by the application of Machine Learning and Deep Learning in these areas. Summarily, after analysis of numerous papers, it is concluded that Machine Learning and Deep Learning are widely utilized in waste biomass production areas to enhance the waste collecting quality and quality, improve the predictions, diminish the losses, as well as increase storage and transformation conditions.