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Article QRS (Quality-Reliability-Safety) Complex of Engineering: Its Importance and Necessity in Engineering Education(SAGE Publications Inc., 2026) Eryilmaz, S.Although quality, reliability and safety are well-known concepts, the importance of these concepts has increased even more considering today's technologies and integrated systems. It is important that these concepts are known by engineers who play an important role in the design of such systems. This article aims to emphasize the importance and necessity of teaching the triple of quality, reliability and safety, expressed with the acronym QRS, in engineering education. In particular, the definitions of these concepts, the relationships between them and the basic issues that should be known by any engineering student regarding these concepts are summarized. Some suggestions are offered to help engineering students gain competence in these subjects. © The Author(s) 2026Book Part Citation - Scopus: 1Safety, Toxicity Profile and Side Effects(Springer Science+Business Media, 2025) Demirci Saadet, E.; Türsen, B.Since Janus kinases mediate the effects of numerous inflammatory cytokines, various side effects are observed during treatment with JAK inhibitors that inhibit these kinases. Infections are the most common side effects. The development of malignancy, venous thromboembolism, major cardiovascular adverse events, nausea, acne, and various laboratory abnormalities has also been observed with the use of JAK inhibitors. With the long-term use of JAK inhibitors, their safety, toxicity and side effect profiles are better understood. © 2025 The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG.
