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Book Part Citation - Scopus: 2Trace Element Containing Nano-HAp for Preventing Musculoskeletal Infections(Springer Science and Business Media B.V., 2021) Gizer,M.; Boyacıoğlu,Ö.; Korkusuz,P.; Korkusuz,F.Musculoskeletal infections are difficult to diagnose and rapidly reach the chronic phase that is difficult to treat. Osteomyelitis and septic arthritis are inflammatory musculoskeletal diseases and their recovery should contain bone or joint regeneration approaches. Nanometer-sized hydroxyapatite is the main inorganic component of the bone tissue that resembles its extracellular matrix. Nanometer-sized hydroxyapatite composite is also an efficient carrier for various regenerative molecules and medicine. Trace elements on the other hand enhance bone formation, mineralization and have antibacterial properties. Bioactivity, biocompatibility, and antibacterial properties of nanometer-sized hydroxyapatite can be gained and improved with trace elements such as zinc, boron, magnesium, strontium, and molybdenum. This chapter summarizes studies on the effects of zinc, boron, magnesium, strontium, and/or molybdenum-doped nanometer-sized hydroxyapatite that can be used to treat musculoskeletal infections. © 2021, The Author(s), under exclusive license to Springer Nature Switzerland AG.Article Minimization of Greenhouse Effects by Optimal Plankton Feeding: A Simulation-Based Study(Springer Science and Business Media B.V., 2025) Doruk, R.O.Global warming and related greenhouse effects possess significant threats to environmental sustainability. This research investigates the possibility of reducing the greenhouse gas levels and associated ambient temperature by manipulating the plankton population in a given forecasting period. To achieve this goal, an optimal control strategy is developed by Pontryagin’s minimum principle, and it is applied to a recently derived nonlinear marine ecosystem model describing the variation of greenhouse gas levels, ambient temperature, and fish interactions. The main goal is to determine an external plankton generation profile that is expected to reduce the greenhouse gas levels and associated ambient temperature to the highest possible extent. The simulation results reveal that the optimal feeding strategy enables one to achieve a reduction of 54% in greenhouse gas levels and 95% in the associated ambient temperature. This research proposes a biological-based novel control approach that can serve as an alternative solution to environmental degradation. © 2025 Elsevier B.V., All rights reserved.
