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Article Citation - WoS: 6Citation - Scopus: 6Which Is Better To Predict Erectile Dysfunction and Male Sexual Function in the Context of Metabolic Syndrome: Triglyceride-Glucose Index or Visceral Adiposity Index?: a Retrospective Cross-Sectional Study(Springer, 2024) Bolat, Mustafa Suat; Bolat, Ipek Akalin; Dundar, Cihad; Asci, RamazanPurposeMany factors influence male sexual function, including metabolic disorders such as metabolic syndrome (MetS). We aimed to investigate the effects of two metabolic indices, the triglyceride-glucose (TyG) index and the visceral adiposity index (VAI), on male sexual function.MethodsA total of 400 men having sexual dysfunction were included. Anthropological data, comorbidities were recorded. Serum total testosterone, prolactin, and estradiol levels were recorded. Sex-specific VAI was calculated using the [(WC/39.68) + (1.88xMI)] x (TG/1.03) x (1.31/HDL) formula and using Ln (fasting triglycerides) x (fasting glucose)/2] formula, TyG index was calculated. Turkish-validated 15-item long-form of the International Index of Erectile Dysfunction (IIEF) questionnaire and male sexual health questionnaire (MSHQ) were used for erectile function and ejaculatory function, respectively. The ROC analysis was used to evaluate the predictive abilities of TyG and VAI cut-off values for ED risk.ResultsA higher TyG index and VAI were associated with an increased risk of ED. The presence of MetS further worsened sexual function, with lower scores in sexual satisfaction, orgasm, desire, and general satisfaction. The TyG index and VAI showed similar predictive abilities for ED. Patients with MetS had worse ejaculation quality compared to those without MetS.ConclusionsThese findings highlight the potential of the TyG index and VAI as convenient tools for predicting and assessing sexual dysfunction in men, particularly in the context of metabolic disorders. Early detection and intervention for metabolic syndrome and insulin resistance may help to mitigate their negative impact on male sexual function.Article Citation - WoS: 2Citation - Scopus: 2Structural Design Optimization of Multi-Layer Spherical Pressure Vessels: a Metaheuristic Approach(Springer, 2019) Akis, Tolga; Azad, Saeid KazemzadehThis study addresses the optimum design problem of multi-layer spherical pressure vessels based on von Mises yield criterion. In order to compute the structural responses under internal pressure, analytical solutions for one-, two-, and three-layer spherical pressure vessels are provided. A population-based metaheuristic algorithm is reformulated for optimum material selection as well as thickness optimization of multi-layer spherical pressure vessels. Furthermore, in order to enhance the computational efficiency of the optimization algorithm, upper bound strategy is also integrated with the algorithm for reducing the total number of structural response evaluations during the optimization iterations. The performance of the algorithm is investigated through weight and cost minimization of one-, two- and three-layer spherical pressure vessels and the results are presented in detail. The obtained numerical results, based on different internal pressures as well as vessel sizes, indicate the usefulness and efficiency of the employed methodology in optimum design of multi-layer spherical pressure vessels.Article Citation - WoS: 14Citation - Scopus: 14Fuzzy Logic Model To Estimate Seasonal Pseudo Steady State Chlorophyll-A Concentrations in Reservoirs(Springer, 2004) Soyupak, S; Chen, DGA fuzzy logic model is developed to estimate pseudo steady state chlorophyll-a concentrations in a very large and deep dam reservoir, namely Keban Dam Reservoir, which is also highly spatial and temporal variable. The estimation power of the developed fuzzy logic model was tested by comparing its performance with that from the classical multiple regression model. The data include chlorophyll-a concentrations in Keban lake as a response variable, as well as several water quality variables such as PO4 phosphorus, NO3 nitrogen, alkalinity, suspended solids concentration, pH, water temperature, electrical conductivity, dissolved oxygen concentration and Secchi depth as independent environmental variables. Because of the complex nature of the studied water body, as well as non-significant functional relationships among the water quality variables to the chlorophyll-a concentration, an initial analysis is conducted to select the most important variables that can be used in estimating the chlorophyll-a concentrations within the studied water body. Following the outcomes from this initial analysis, the fuzzy logic model is developed to estimate the chlorophyll-a concentrations and the advantages of this new model is demonstrated in model fitting over the traditional multiple regression method.Article Citation - Scopus: 1Surface Patterning of Poly(ε-Caprolactone) Scaffolds by Electrospinning for Monitoring Cell Biomass Behavior(Springer, 2022) Albayrak, Deniz; Sasmazel, Hilal TurkogluThe aim of this work was to produce three-dimensional fibrous surface patterns of poly(epsilon-caprolactone) (PCL), onto two-dimensional smooth solvent cast PCL surfaces with an electrospinning method by using a mask/stencil for monitoring cell biomass behavior. The characterizations of produced scaffolds were done by thickness measurements, scanning electron microscopy (SEM) analyses, contact angle (CA) measurements, Fourier-transform infrared spectroscopy (FTIR), and mechanical tests. According to SEM micrographs, all of the electrospun scaffold surfaces exhibited bead-free and uniform morphology while solvent cast surfaces were smooth and nonporous. CA measurements revealed that the solvent cast surfaces had moderate hydrophilicity (similar to 60 degrees) while electrospun regions had a more hydrophobic character (similar to 110 degrees for fully electrospun surfaces and similar to 85 degrees for electrospun patterns). Mechanical testing showed the produced scaffolds had a brittle character. Moreover, cell culture studies were performed with mouse fibroblast (L929) cells for 7 days period, and cell attachment assay, MTT assay, fluorescence, and SEM analyses were done. Cell culture studies indicated that the solvent cast and electrospun patterns have different characteristics for cell behavior. Thus, cell movement, attachment, and proliferation can be directed and monitored by obtaining different surface topographies in a single substrate surface. Based on the results of this study, it was found that patterns consisting of polymeric nanofiber structures can also be created directly by the electrospinning method.Article Citation - WoS: 22Citation - Scopus: 23On Residual Lifetime of Coherent Systems After the rth Failure(Springer, 2013) Eryilmaz, SerkanIn this article we study the residual lifetime of a coherent system after the rth failure, i.e. the time elapsed from the rth failure until the system failure given that the system operates at the time of the rth failure. We provide a mixture representation for the corresponding residual lifetime distribution in terms of signature. We also obtain some stochastic ordering results for the residual lifetimes.Article Citation - WoS: 5Citation - Scopus: 5Automorphisms of the mapping class group of a nonorientable surface(Springer, 2017) Atalan, Ferihe; Szepietowski, BlazejLet S be a nonorientable surface of genus g >= 5 with n >= 0 punctures, and Mod(S) its mapping class group. We define the complexity of S to be the maximum rank of a free abelian subgroup of Mod(S). Suppose that S-1 and S-2 are two such surfaces of the same complexity. We prove that every isomorphism Mod(S-1) -> Mod(S-2) is induced by a diffeomorphism S-1 -> S-2. This is an analogue of Ivanov's theorem on automorphisms of the mapping class groups of an orientable surface, and also an extension and improvement of the first author's previous result.Editorial Special Issue: International Workshop in Applied Probability 2014(Springer, 2016) Eryilmaz, S.; Koutras, Markos V.[No Abstract Available]Article Citation - WoS: 2Citation - Scopus: 1Computing Waiting Time Probabilities Related To (k1< k2< ..., kl< Pattern(Springer, 2023) Chadjiconstantinidis, Stathis; Eryilmaz, SerkanFor a sequence of multi-state trials with l possible outcomes denoted by {1, 2, ..., l}, let E be the event that at least k(1) consecutive is followed by at least k(2) consecutive 2s,..., followed by at least k(l) consecutive ls. Denote by T-r the number of trials for the rth occurrence of the event E in a sequence of multi-state trials. This paper studies the distribution of the waiting time random variable T-r when the sequence consists of independent and identically distributed multi-state trials. In particular, distributional properties of T-r are examined via matrix-geometric distributions.Article Citation - WoS: 27Citation - Scopus: 30The Distributions of Sum, Minima and Maxima of Generalized Geometric Random Variables(Springer, 2015) Tank, Fatih; Eryilmaz, SerkanGeometric distribution of order as one of the generalization of well known geometric distribution is the distribution of the number of trials until the first consecutive successes in Bernoulli trials with success probability . In this paper, it is shown that this generalized distribution can be represented as a discrete phase-type distribution. Using this representation along with closure properties of phase-type distributions, the distributions of sum, minima and maxima of two independent random variables having geometric distribution of order are obtained. Numerical results are presented to illustrate the computational details.Article Citation - WoS: 1Citation - Scopus: 1Principal and Nonprincipal Solutions of Impulsive Dynamic Equations: Leighton and Wong Type Oscillation Theorems(Springer, 2023) Zafer, A.; Akgol, S. DogruPrincipal and nonprincipal solutions of differential equations play a critical role in studying the qualitative behavior of solutions in numerous related differential equations. The existence of such solutions and their applications are already documented in the literature for differential equations, difference equations, dynamic equations, and impulsive differential equations. In this paper, we make a contribution to this field by examining impulsive dynamic equations and proving the existence of such solutions for second-order impulsive dynamic equations. As an illustration, we prove the famous Leighton and Wong oscillation theorems for impulsive dynamic equations. Furthermore, we provide supporting examples to demonstrate the relevance and effectiveness of the results.
