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Article Citation - WoS: 4Citation - Scopus: 3Evaluation of Hepatosteatosis in Patients With Chronic Hepatitis B Virus Infection(Elsevier, 2023) Sayar, Merve Sefa; Bulut, Dilek; Acar, AliBackground and study aims: The current study aimed to investigate the frequency of hepatic steatosis in chronic hepatitis B (CHB) patients and determine the possible risk factors associated with its presence.Patients and methods: This cross-sectional study retrospectively evaluated the medical records of 255 adult CHB patients visiting an infectious disease outpatient clinic. Patients with hepatitis B surface anti-gen positivity for >6 months and those who did not receive antiviral therapy were included in the study. The presence and stage of hepatic steatosis were determined through hepatobiliary ultrasonography.Results: The mean age of the patients was 40.6 +/- 12.7 years. Hepatic steatosis was detected in 44.4 % of the patients through ultrasound imaging. Our findings showed that the detected steatosis prevalence in our patients with CHB was significantly higher compared to the highest prevalence of non-alcoholic steatohepatitis found in the general Turkish population (19.9 %) [RR 2.23 (1.75-2.86), p < 0.001]. CHB patients with steatosis had significantly higher age, triglyceride, and gamma-glutamyl transferase levels than those without steatosis (p < 0.05). No significant association was found between the presence of steatosis, sex, liver function test results, and platelet, alkaline phosphatase, cholesterol, alpha fetoprotein, or HBV-DNA levels. No significant relationship was found between aspartate aminotransferase (AST)/platelet ratio index (APRI) and steatosis was examined (p > 0.05). Post-hoc analysis showed a sig-nificant relationship between HBV-DNA levels and ALT, AST, and APRI scores.Conclusion: Our data showed that hepatic steatosis is more common in CHB patients than in the general population. Older age and high triglyceride levels increased the risk of hepatic steatosis in CHB patients, consequently increasing GGT levels, which are indicative of liver damage, in these patients.(c) 2022 Pan-Arab Association of Gastroenterology. Published by Elsevier B.V. All rights reserved.Article Citation - WoS: 25Citation - Scopus: 33Dynamic Behavior of k-out-of-n< Systems(Elsevier, 2011) Eryilmaz, SerkanIn this paper, we study the distribution and expected value of the number of working components at time t in usual and weighted k-out-of-n:G systems under the condition that they are working at time t. We evaluate the distribution of the corresponding conditional random variable and compute its expected value for the systems consisting of independent but nonidentical components. Illustrative examples are presented and an optimization problem which makes use of the conditional random variable is also formulated and solved numerically. (c) 2011 Elsevier B.V. All rights reserved.Article Citation - WoS: 6Citation - Scopus: 6On δ-shock model with a change point in intershock time distribution(Elsevier, 2024) Chadjiconstantinidis, Stathis; Eryilmaz, SerkanIn this paper, we study the reliability of a system that works under o-shock model. That is, the system failure occurs when the time between two successive shocks is less than a given threshold o. In a traditional setup of the o shock model, the intershock times are assumed to have the same distribution. In the present setup, a change occurs in the distribution of the intershock times due to an environmental effect. Thus, the distribution of the intershock times changes after a random number of shocks. The reliability of the system is studied under this change point setup.
