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Article Citation - WoS: 12Citation - Scopus: 13Novel Pt(ii) Complexes Containing Pyrrole Oxime, Synthesis, Characterization and Dna Binding Studies(Elsevier, 2014) Erdogan, Deniz Altunoz; Ozalp-Yaman, SenizSince the discovery of anticancer activity and subsequent clinical success of cisplatin (cis-[PtCl2(NH3)(2)]), platinum-based compounds have since been widely synthesized and studied as potential chemotherapeutic agents. In this sense, three novel nuclease active Pt(II) complexes with general formula; [Pt(NH3)CI(L)] (1), [Pt(L)(2)] (2), and K[PtCl2(L)] (3) in which L is 1-H-pyrrole-2-carbaldehyde oxime were synthesized. Characterization of complexes was performed by elemental analysis, FT-IR, H-1 NMR and mass spectroscopy measurements. Interaction of complexes (1-3) with calf thymus deoxyribonucleic acid (ct-DNA) was investigated by using electrochemical, spectroelectrochemical methods and cleavage studies. The hyperchromic change in the electronic absorption spectrum of the Pt(II) complexes indicates an electrostatic interaction between the complexes and ct-DNA. Binding constant values between 4.42 x 10(3) and 5.09 x 10(3) M-1 and binding side size values between 2 and 3 base pairs were determined from cyclic voltammetry (CV) and differential pulse voltammetry (DPV) studies. (C) 2014 Elsevier B.V. All rights reserved.Book Part Fuel Cell Energy Conversion(Elsevier, 2025) Ercelik, M.; Nalbant, Y.; Çolpan, C.; Ismail, M.S.Fuel cells are electrochemical devices that convert the chemical energy of the fuel into electrical energy directly. There are different types of fuel cells, which can be categorized according to their electrolyte type and fuel used. The performance of these fuel cells mainly depends on the materials of their components and the manufacturing method. In this chapter, an introduction to different fuel cell types, the materials and manufacturing methods that can be used for fuel cells, and characterization techniques are first presented. Then, the basic concepts and equations for the thermodynamics and electrochemistry of fuel cells are given. The principles of fuel cell stack design including the calculations of pressure drop within a flow field are discussed. Energy and exergy analyses of integrated fuel cells systems are also presented. This chapter also covers several illustrative examples and a case study on the mathematical modeling of fuel cells. © 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.
