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  • Article
    Effect of COVID-19 Infection on the Performance of Elite Adolescent Overhead Athletes
    (SAGE Publications Ltd, 2025) Uluǧ, Naime; Kodak, Seyde Büşra; Kodak, Muhammed Ihsan,; Karahan, Zehra Can; Kiliç, Erden
    Background: COVID-19 might have a negative impact on sports performance. There are few studies in the literature that assess how the sports performance of adolescent athletes is affected by COVID-19. Objective: This study aimed to compare the sports performance of adolescent overhead athletes who had COVID-19 infection with those who had not. Methods: The study involved adolescent elite overhead athletes from basketball, volleyball, handball, and tennis. Athletes’ performance were assessed using core muscle endurance, hand grip strength, upper extremity functional performance, reaction time and agility performance, and the 3-min step test. Results: Study included 47 adolescent overhead athletes (mean age 15.15 ± 1.51 years). The COVID-19 group showed significantly higher Borg Scale scores and decrease in oxygen saturation levels only after the step test (p = 0.02, p = 0.02, respectively). Additionally, COVID-19 group had lower grip strength in both right and left hands compared to the non-COVID group (p = 0.01, p = 0.05, respectively). No significant association was found between core muscle power and endurance, upper extremity functional performance, reaction time and agility performance (p > 0.05). Conclusions: Our results showed reduced hand grip strength and increased fatigue following COVID-19 infection in adolescent overhead athletes. Time period after COVID-19 infection had a negative correlation with sports performance and core endurance. © 2025 Elsevier B.V., All rights reserved.
  • Article
    A Comparative Analysis of Progestin-Primed Ovarian Stimulation Versus GnRH Antagonists Protocols Pertaining To Stimulation Parameters and Embryological Outcomes in Patients With Endometrioma
    (Frontiers Media SA, 2025) Boynukalin, Fazilet Kübra; Tohma, Yusuf Aytaç; Gültomruk, Meral; Yarkiner, Zalihe; Akkaya, Ceren Melisa; Özkavukçu, Sinan; Bozdaǧ, Gürkan
    Research question: Do embryo parameters and live birth rates differ between patients with endometrioma undergoing a freeze-all strategy using either GnRH antagonists or progestin-primed ovarian stimulation (PPOS)? Design: This retrospective cohort study was conducted at Bahceci Health Group from January 2021 to January 2023. Inclusion criteria were females aged 20–40 with confirmed endometriosis, using either GnRH antagonists or PPOS ovarian stimulation, and opting for freezing all embryos without fresh embryo transfer (ET). A total of 543 patients were analyzed, with the primary outcome being usable embryos at cleavage stage and secondary outcomes including distribution of embryo quality, clinical pregnancy, and live birth rate. Results: For the GnRH antagonist arm, the median (25th-75th percentiles) total gonadotropin dose required during stimulation was significantly higher (2725 [2100–3587.5] vs. 2400 [2050–3075] IU, p = 0.001) and duration was longer (11 [10–12] vs. 10 [9–11] days, p = 0.01), although number of mature oocytes and maturation and fertilization rates were similar in both arms. However, the linear regression analysis revealed that the number of usable day-three embryos was higher with the PPOS protocol than with the GnRH antagonist protocol (OR: 0.890, CI 95%: 0.226 – 1.554, p= 0.009). Particularly in patients that had undergone FET, the respective live birth rates were 50.0% and 54.6% in GnRH antagonist and PPOS arms, respectively, without any statistical significance (p= 0.365). Conclusion: In patients with endometrioma, the PPOS protocol over GnRH antagonists might potentially enhance the quantity of usable cleavage-stage embryos while showing no significant impact on the number of collected oocytes. © 2025 Elsevier B.V., All rights reserved.