2 results
Search Results
Now showing 1 - 2 of 2
Article Neuron Modeling: Estimating the Parameters of a Neuron Model From Neural Spiking Data(Tubitak Scientific & Technological Research Council Turkey, 2018) Doruk, Resat Ozgur; Doruk, OzgurWe present a modeling study aiming at the estimation of the parameters of a single neuron model from neural spiking data. The model receives a stimulus as input and provides the firing rate of the neuron as output. The neural spiking data will be obtained from point process simulation. The resultant data will be used in parameter estimation based on the inhomogeneous Poisson maximum likelihood method. The model will be stimulated by various forms of stimuli, which are modeled by a Fourier series (FS), exponential functions, and radial basis functions (RBFs). Tabulated results presenting cases with different sample sizes (# of repeated trials), stimulus component sizes (FS and RBF), amplitudes, and frequency ranges (FS) will be presented to validate the approach and provide a means of comparison. The results showed that regardless of the stimulus type, the most effective parameter on the estimation performance appears to be the sample size. In addition, the lowest variance of the estimates is obtained when a Fourier series stimulus is applied in the estimation.Review Frailty, Sarcopenia and Nutrition(Ankara Yildirim Beyazit University, 2024) Yesil,B.O.; Okur,İ.N.; Hızlı,Ş.Recently, the terms frailty and sarcopenia have been used frequently. Frailty, which occurs due to age-related physiological changes in multiple systems, is accepted as one of the geriatric syndromes. In frailty, negative energy balance, decreased strength, slowed walking speed, decreased grip strength, sarcopenia and involuntary weight loss can be seen. Frailty emerges as an indicator of biological age and correlates with the outcomes of biological age regardless of age, gender and comorbidities. Recent studies have begun to use the concept of frailty in children. Frailty in children is caused by a multi-system physiological impairment, including neurological, endocrine, immune and skeletal systems, which leads to a deterioration in quality of life. Frail children therefore require additional care and related services compared to children of the same age. Sarcopenia is defined as progressive loss in the musculoskeletal system. It has been determined that frailty and sarcopenia have many things in common in terms of their formation mechanisms, clinical consequences, treatment and prevention methods. Nutrition is closely related to both frailty and sarcopenia. Therefore, adequate energy and protein intake is extremely important in preventing malnutrition and loss of lean body mass. © 2024 Ankara Yildirim Beyazit University. All rights reserved.
