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Article Citation - WoS: 2Citation - Scopus: 2Physics-Informed Neural Network for Nonlinear Bending Analysis of Nano-Beams: A Systematic Hyperparameter Optimization(MDPI, 2025) Esfahani, Saba Sadat Mirsadeghi; Fallah, Ali; Aghdam, Mohammad Mohammadi; Mohammadi Aghdam, Mohammad; Mirsadeghi Esfahani, Saba SadatThis paper investigates the nonlinear bending analysis of nano-beams using the physics-informed neural network (PINN) method. The nonlinear governing equations for the bending of size-dependent nano-beams are derived from Hamilton's principle, incorporating nonlocal strain gradient theory, and based on Euler-Bernoulli beam theory. In the PINN method, the solution is approximated by a deep neural network, with network parameters determined by minimizing a loss function that consists of the governing equation and boundary conditions. Despite numerous reports demonstrating the applicability of the PINN method for solving various engineering problems, tuning the network hyperparameters remains challenging. In this study, a systematic approach is employed to fine-tune the hyperparameters using hyperparameter optimization (HPO) via Gaussian process-based Bayesian optimization. Comparison of the PINN results with available reference solutions shows that the PINN, with the optimized parameters, produces results with high accuracy. Finally, the impacts of boundary conditions, different loads, and the influence of nonlocal strain gradient parameters on the bending behavior of nano-beams are investigated.Article Citation - WoS: 3Citation - Scopus: 3Characterization of Mesenchymal Stem Cells in Mucolipidosis Type Ii (i-Cell Disease)(Tubitak Scientific & Technological Research Council Turkey, 2019) Köse, Sevil; Kaya, Fatima Aerts; Kuşkonmaz, Bülent Barış; Çetinkaya, Duygu Uçkan; Aerts Kaya, Fatima; Uckan Cetinkaya, DuyguMucolipidosis type II (ML-II, I-cell disease) is a fatal inherited lysosomal storage disease caused by a deficiency of theenzyme N-acetylglucosamine-1-phosphotransferase. A characteristic skeletal phenotype is one of the many clinical manifestationsof ML-II. Since the mechanisms underlying these skeletal defects in ML-II are not completely understood, we hypothesized that adefect in osteogenic differentiation of ML-II bone marrow mesenchymal stem cells (BM-MSCs) might be responsible for this skeletalphenotype. Here, we assessed and characterized the cellular phenotype of BM-MSCs from a ML-II patient before (BBMT) and afterBM transplantation (ABMT), and we compared the results with BM-MSCs from a carrier and a healthy donor. Morphologically, wedid not observe differences in ML-II BBMT and ABMT or carrier MSCs in terms of size or granularity. Osteogenic differentiation wasnot markedly affected by disease or carrier status. Adipogenic differentiation was increased in BBMT ML-II MSCs, but chondrogenicdifferentiation was decreased in both BBMT and ABMT ML-II MSCs. Immunophenotypically no significant differences were observedbetween the samples. Interestingly, the proliferative capacity of BBMT and ABMT ML-II MSCs was increased in comparison to MSCsfrom age-matched healthy donors. These data suggest that MSCs are not likely to cause the skeletal phenotype observed in ML-II, butthey may contribute to the pathogenesis of ML-II as a result of lysosomal storage-induced pathology.Article Citation - Scopus: 62Weak ø-Contraction on partial metric spaces(Eudoxus Press, LLC, 2012) Karapinar,E.In this manuscript, the notion of weak ø-contraction is considered on partial metric space. It is shown that a self mapping T on a complete partial metric space X has a fixed point if they satisfied weak ø-contraction. © 2012 EUDOXUS PR20E6SS, LLC.Article Citation - Scopus: 3The early Turkestani émigré struggle and turkestanism: Nation – imagining in emigration: 1925-1940;(Ahmet Yesevi University, 2016) Karasar,H.A.The early Turkestani émigré struggle was an important example of ‘nation imagining’ in emigration. In this article, the challenges faced by Turkestani nationalist leaders who had left their fatherland after the Bolshevik invasion of their country are examined. The activities of émigré leaders and pan-Turkists like Zeki Velidî Togan, Mustafa Çokayoğlu, Osman Hoca and Nihal Atsız are illustrated in some detail. Special attention is given to policy formation, propaganda tactics, the use of media (mainly by publishing periodicals), and the organization of NGOs with the mission of setting and uniting the public (in diaspora) against Russian invasion. It is hoped that this discussion will enable researchers to make better assessments of the past and intelligent projections for the future. The work is based on extensive original sources, most of which have not been exploited before in English language publications. © 2016, Ahmet Yesevi University. All rights reserved.Article Orhan Pamuk’s İstabul Carved in His Memory as a Source of Melancholy(Cyprus International University, 2018) Tekin, KuğuBu makale Orhan Pamuk’un İstanbul Hatıralar ve Şehir başlıklı romanındaki melankolik İstanbul imgesinin yazarın hafızasındaki yansımalarını incelemiştir. Yazara göre İstanbul’dan başka çok az şehir bu imgenin yaratığı derin melankoli duygusuna aynı ölçüde eşlik eden mutluluğa sahiptir. Makale romandaki melankoli yüklü İstanbul imgesini yaratırken yazara ilham veren kaynakları araştırmıştır. Görülüyor ki yazarın romanda da minnettarlığını sıkça ifade ettiği başlıca dört yazar Pamuk’un hafızasında yer eden İstanbul hatıralarını biçimlendirmiştir. Bu yazarlardan ilk ikisi Yahya Kemal Beyatlı ve Ahmet Hamdi Tanpınar’dır ve her ikisi de Fransız yazarlar Gerard de Nerval ve Theophile Gautier’in İstanbul izlenimlerinden etkilenmişlerdir. Özellikle Gautier’in Constantinople başlıklı gezi yazıları Yahya Kemal ve Tanpınar’ı derinden etkilemiş ve bu yazarların İstanbullular için farklı ve yerli bir İstanbul imgesi yaratmalarını sağlamıştır. Bu şehir imgesini farklı ve özgün kılan, güzel olanla, biçimsiz, sefil ve acınası olanın bir araya gelerek oluşturduğu melankoli duygusunun, çökmüş bir imparatorluğun kalıntıları üzerinde yükselerek şehre hâkim olmasıdır. Romanda esinlendiği yazarların adımlarını takip eden Pamuk bir yandan da yirminci yüzyıl İstanbul’unda meydana gelen kültürel, sosyal, siyasi ve çevresel değişimlerle iç içe geçen kendi çocukluk ve ilk gençlik dönemlerini hikâye etmiştir. Makalenin kuramsal çerçevesini Freud, Kristeva ve Peter Schwenger gibi yazarların görüşleri oluşturmuştur.Article Citation - Scopus: 2A New Formulation for the Boundary Element Analysis of Heat Conduction Problems With Nonlinear Boundary Conditions;(Turk Isı Bilimi ve Teknigi Dernegi, 2019) Baranoğlu,B.An effective numerical method based on the boundary element formulation is presented to solve heat conduction equations which are governed by the Fourier equation, with nonlinear boundary conditions on one or more sections of the prescribed boundary. The solution involves the manipulation of the system matrices of the boundary element method and obtaining a smaller ranked matrix equation in which the unknown is only the temperature difference over the nonlinear boundary condition region. This way, the iterations to deal with the nonlinear conditions are performed faster. After finding the solution over the nonlinear boundary condition region, the solution over the entire boundary is obtained as a post-process through a prescribed relation. An example with a proven exact solution is employed to assess the results. © 2019 TIBTD Printed in TurkeyConference Object Citation - Scopus: 1A New E-Commerce Model Suggestion of Agricultural Products(Springer international Publishing Ag, 2024) Eryilmaz, Meltem; Briman, Mohammed Khalid Hilmi; Yakut, GokceThis study aims to create an e-commerce application that enables farmers to sell their products directly to their customers without resorting to intermediaries by a smart cargo box. It presents a method by which the agricultural industry can gain momentum in e-commerce. The main contributions of the study are an e-commerce application that enables farmers to sell their products directly to the customer without the need for an intermediary and the design and implementation of a smart cargo box that is tailored to carry agricultural items throughout the delivery process that locks and unlocks only via QR code generated by the application after order. Django FrameworkNext.js, React.js, and Redux are used for the system development. The database is created with PostgreSQL using migrations, and AmazonWeb Services is used for this database. The "ESP32 Cam" is used to read the QR Code.Conference Object Yazilim Mühendisligi Egitiminde Bitirme Projesinin Yürütülmesinde İki Farkli Yöntemin Ögrenci Bakis Açisiyla Degerlendirilmesi(CEUR-WS, 2015) Karakaya,M.; Bostan,A.[No abstract available]Other Current Induction Therapy Strategies and Anti-T Lymphocyte Globulin Usage in Kidney Transplantation: Consensus-Based Recommendations by a Turkish Expert Panel(Aves, 2024) Çakır, Ülkem; Dinçkan, Ayhan; Karadoğan, Nayim; Keven, Kenan; Koçak, Hüseyin; Koç, Serkan Kubilay; Yıldız, Alaattin; Turkmen, Aydin; Töz, Hüseyin; Sezer, SirenThis advisory committee convened to review national and global kidney transplantation dynamics and provide recom- mendations on the use of anti-T lymphocyte globulin (ATLG) for prevention and treatment of rejection after allogeneic kidney transplantation. A critical evaluation of 6 relevant articles released up to October 2022 was performed to reveal their importance in clinical practice. Additionally, 27 key questions on the indication, dosage of ATLG, and risk stratification were used for the Delphi technique with 8 members of the Turkish Society of Nephrology including 5 kidney transplanta- tion (KTx) subcommittee members and a surgeon experienced in solid organ transplantation. The committee declared that Türkiye had great potential in KTx; however, increase in transplantation would be possible in the case of raise in the deceased donor transplantation. As a consensus, ATLG was strongly recommended for induction and rejection treatment. Also, committee members recommended the safe dosage range in steroid resistant acute rejection as 2.5-3 mg/kg daily for 5-7 days, and the median of preferred dosage in induction sounded as 2-2.5 mg/kg daily for 3 days in intermediate risk state. Additionally, post-transplant infection and malignancy cases due to immunosuppression were much rarely encoun- tered than they were in the past.Article Citation - WoS: 2Citation - Scopus: 5Scattering of Plane Waves at the Junction of Two Corrugated Half-Planes(Taylor & Francis inc, 2005) Serbest, AH; Kara, A; Lueneburg, E; Lüneburg, ErnstIn this paper, the boundary conditions given by Weinstein ( 1969) are employed to simulate two corrugated half-planes with the same slot height but different slot width. The scattering mechanism at the junction of these half-planes is investigated via the Fourier transform technique, which leads to two coupled Wiener - Hopf equations. The solution of the Wiener - Hopf system is obtained by the Daniele - Khrapkov method and some numerical results are presented about the analysis of the scattered field.
