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Institution Author: Saadet, Elif DemirciLanguage: en

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    Article
    Analysis of the Relationship Between Clinical Features, Treatment Options and Recurrence of Patients Diagnosed With Anogenital Warts
    (2023) Saadet, Elif Demirci; İnal, Halil Gürdal; Seçkin, Bedreddin; Akarsu, Süleyman; İnal, Gurdal
    Aims: Our study aimed to describe the demographic and clinical characteristics of patients with anogenital warts and to investigate the relationship between treatment options and recurrence. Methods: The data of patients who were admitted to the dermatology, urology, and gynecology outpatient clinics between 2010 and 2021, and diagnosed with anogenital warts were retrospectively analyzed. Demographic characteristics of the patients, presence of other sexually transmitted diseases, anatomical distribution of warts, number of anatomical regions and warts, frequency of recurrence, type of treatment before the first recurrence, and follow-up periods were documented. Statistical analysis was performed and the results were evaluated at a 95% confidence interval and p<0.05. Results: A total of 201 patients, 181 (90%) male and 20 (10%) female, who met the study criteria, were included in the study. The ages of the patients vary between 20-67 years; the median was 31 years. The rate of the number of warts of 10 or more in patients with recurrence was found to be statistically significantly higher than in cases without recurrence (p=0.013). The recurrence rate was statistically significantly higher in patients with pubic localization (p=0.001). There was a significant difference between the number of localization regions according to recurrence status (p=0.003). The recurrence rate of patients who received cryotherapy was statistically significantly higher (p=0.002). According to the logistic regression analysis; the number of 10 or more warts increases the risk of recurrence to 2.665 times (95% CI: 1.225-5.799) (p=0.013). Cryotherapy increases the risk of recurrence to 6.243 times (95% CI: 1.786-21.828) (p=0.004). Male sex increases the risk of recurrence to 3.034 times (95% CI: 1.029-8.940) (p=0.044). Conclusion: Anogenital warts often recur even if they disappear completely after treatment. It has been observed that the recurrence is more common when the number of warts is more than 10. Recurrence may be observed more frequently in the male gender. Recurrence occurs more frequently with cryotherapy than electrocauterization. The importance of prophylactic human papillomavirus vaccination in preventing anogenital warts is emerging once again due to the high recurrence rate and prolonged treatment period.
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    Article
    Herpes Zoster Hastalarının Demografik ve Klinik Özelliklerinin Değerlendirilmesi
    (Selcuk University, 2023) Demirci Saadet, E.; Hasanbeyzade, S.; Hasanbeyzade, Sabir; Saadet, Elif Demırcı
    Background: Herpes zoster is a disease that is more frequently seen in people aged over 50 years and negatively affects the quality of life due to the development of post-herpetic neuralgia. This study aimed to investigate the demographic and clinical characteristics of patients diagnosed with herpes zoster. Methods: In this cross-sectional study, the data of patients who were followed up with a diagnosis of herpes zoster at the dermatology department between 2013 and 2020 were retrospectively examined. Results: Of 440 patients, 252 (57.3%) were female and 188 (42.7%) were male. The mean age was 48.9±18 (4-94) years. The most common localization was the thoracic region at a rate of 35.5% and the lumbar region at a rate of 21.4%. Disseminated and ophthalmic zoster were more common in elderly patients (p<0.001). The most common comorbidities were hypertension (HT)+coronary artery disease (CAD) (12.6%), cancer (10.3%), and diabetes+HT (5.9%). Severe pain was observed in 19.7% of the patients and was more common in women (p=0.016). The rate of moderate and severe pain was high in the patients with HT+CAD and cancer (p˂0.001). Post-herpetic neuralgia was observed in 15.3% of the patients aged over 50. Conclusions: Herpes zoster is especially common in adults. Since it causes acute pain and can lead to postherpetic neuralgia development, risky patient groups should be more carefully followed up and treated. © 2023, Selcuk University. All rights reserved.