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Article Citation - WoS: 3Citation - Scopus: 3Comparison of the Performance of Structural Break Tests in Stationary and Nonstationary Series: a New Bootstrap Algorithm(Springer, 2024) Camalan, Ozge; Hasdemir, Esra; Omay, Tolga; Kucuker, Mustafa CanStructural breaks are considered as permanent changes in the series mainly because of shocks, policy changes, and global crises. Hence, making estimations by ignoring the presence of structural breaks may cause the biased parameter value. In this context, it is vital to identify the presence of the structural breaks and the break dates in the series to prevent misleading results. Accordingly, the first aim of this study is to compare the performance of unit root with structural break tests allowing a single break and multiple structural breaks. For this purpose, firstly, a Monte Carlo simulation study has been conducted through using a generated homoscedastic and stationary series in different sample sizes to evaluate the performances of these tests. As a result of the simulation study, Zivot and Andrews (J Bus Econ Stat 20(1):25-44, 1992) are the best-performing tests in capturing a single break. The most powerful tests for the multiple break setting are those developed by Kapetanios (J Time Ser Anal 26(1):123-133, 2005) and Perron (Palgrave Handb Econom 1:278-352, 2006). A new Bootstrap algorithm has been proposed along with the study's primary aim. This newly proposed Bootstrap algorithm calculates the optimal number of statistically significant structural breaks under more general assumptions. Therefore, it guarantees finding an accurate number of optimal breaks in real-world data. In the empirical part, structural breaks in the real interest rate data of the US and Australia resulting from policy changes have been examined. The results concluded that the bootstrap sequential break test is the best-performing approach due to the general assumption made to cover real-world data.Article Citation - WoS: 1Citation - Scopus: 1On the Rate of Convergence for the q-durrmeyer Polynomials in Complex Domains(Walter de Gruyter Gmbh, 2024) Gurel, Ovgu; Ostrovska, Sofiya; Turan, MehmetThe q-Durrmeyer polynomials are one of the popular q-versions of the classical operators of approximation theory. They have been studied from different points of view by a number of researchers. The aim of this work is to estimate the rate of convergence for the sequence of the q-Durrmeyer polynomials in the case 0 < q < 1. It is proved that for any compact set D subset of C, the rate of convergence is O(q(n)) as n -> infinity. The sharpness of the obtained result is demonstrated.Article Citation - WoS: 13Citation - Scopus: 13Investigating Space Utilization in Skyscrapers Designed with Prismatic Form(Mdpi, 2024) Ilgin, Hueseyin Emre; Aslantamer, Ozlem NurThe enduring appeal of prismatic shapes, historically prevalent in office building designs, persists in contemporary skyscraper architecture, which is attributed particularly to their advantageous aspects concerning cost-efficiency and optimal space utilization. Space efficiency is a crucial factor in prismatic skyscraper design, carrying substantial implications for sustainability. However, the current academic literature lacks a complete exploration of space efficiency in supertall towers with prismatic forms, despite their widespread use. This paper seeks to address this significant gap by conducting a comprehensive analysis of data gathered from a carefully selected set of 35 case studies. The primary discoveries presented in this paper are outlined as follows: (i) average space efficiency stood at approximately 72%, covering a range that extended from 56% to 84%; (ii) average core to gross floor area ratio averaged around 24%, spanning a spectrum that ranged from 12% to 36%; (iii) the majority of prismatic skyscrapers utilized a central core approach, mainly customized for residential use; (iv) the dominant structural system observed in the analyzed cases was the outriggered frame system, with concrete being the commonly utilized material for the structural components; and (v) the impact of diverse structural systems on space efficiency showed no significant deviation, although differences in function led to variations in average space efficiency. The authors expect that these findings will provide valuable guidance, especially for architects, as they strive to enhance the sustainable planning of prismatic towers.Article Effects of Pomegranate Seed Oil on Lower Extremity Ischemia-Reperfusion Damage: Insights into Oxidative Stress, Inflammation, and Cell Death(MDPI, 2025) Bozok, Ummu Gulsen; Ergorun, Aydan Iremnur; Kucuk, Aysegul; Yigman, Zeynep; Dursun, Ali Dogan; Arslan, MustafaAim: This study sought to clarify the therapeutic benefits and mechanisms of action of pomegranate seed oil (PSO) in instances of ischemia–reperfusion (IR) damage in the lower extremities. Materials and Methods: The sample size was determined, then 32 rats were randomly allocated to four groups: Control (C), ischemia–reperfusion (IR), low-dose PSO (IR + LD, 0.15 mL/kg), and high-dose PSO (IR + HD, 0.30 mL/kg). The ischemia model in the IR group was established by occluding the infrarenal aorta for 120 min. Prior to reperfusion, PSO was delivered to the IR + LD and IR + HD groups at doses of 0.15 mL/kg and 0.30 mL/kg, respectively, followed by a 120 min reperfusion period. Subsequently, blood and tissue specimens were obtained. Statistical investigation was executed utilizing Statistical Package for the Social Sciences version 20.0 (SPSS, IBM Corp., Armonk, NY, USA). Results: Biochemical tests revealed significant variations in total antioxidant level (TAS), total oxidant level (TOS), and the oxidative stress index (OSI) across the groups (p < 0.0001). The IR group had elevated TOS and OSI levels, whereas PSO therapy resulted in a reduction in these values (p < 0.05). As opposed to the IR group, TASs were higher in the PSO-treated groups. Histopathological analysis demonstrated muscle fiber degeneration, interstitial edema, and the infiltration of cells associated with inflammation in the IR group, with analogous results noted in the PSO treatment groups. Immunohistochemical analysis revealed that the expressions of Tumor Necrosis Factor-alpha (TNF-α), Nuclear Factor kappa B (NF-κB), cytochrome C (CYT C), and caspase 3 (CASP3) were elevated in the IR group, while PSO treatment diminished these markers and attenuated inflammation and apoptosis (p < 0.05). The findings demonstrate that PSO has a dose-dependent impact on IR injury. Discussion: This research indicates that PSO has significant protective benefits against IR injury in the lower extremities. PSO mitigated tissue damage and maintained mitochondrial integrity by addressing oxidative stress, inflammation, and apoptotic pathways. Particularly, high-dose PSO yielded more substantial enhancements in these processes and exhibited outcomes most comparable to the control group in biochemical, histological, and immunohistochemical investigations. These findings underscore the potential of PSO as an efficacious natural treatment agent for IR injury. Nevertheless, additional research is required to articulate this definitively.Article Citation - WoS: 28Citation - Scopus: 44Digital Transformation Strategies, Practices, and Trends: a Large-Scale Retrospective Study Based on Machine Learning(Mdpi, 2023) Gurcan, Fatih; Boztas, Gizem Dilan; Dalveren, Gonca Gokce Menekse; Derawi, MohammadThe purpose of this research is to identify the areas of interest, research topics, and application areas that reflect the research nature of digital transformation (DT), as well as the strategies, practices, and trends of DT. To accomplish this, the Latent Dirichlet allocation algorithm, a probabilistic topic modeling technique, was applied to 5350 peer-reviewed journal articles on DT published in the last ten years, from 2013 to 2022. The analysis resulted in the discovery of 34 topics. These topics were classified, and a systematic taxonomy for DT was presented, including four sub-categories: implementation, technology, process, and human. As a result of time-based trend analysis, "Sustainable Energy", "DT in Health", "E-Government", "DT in Education", and "Supply Chain" emerged as top topics with an increasing trend. Our findings indicate that research interests are focused on specific applications of digital transformation in industrial and public settings. Based on our findings, we anticipate that the next phase of DT research and practice will concentrate on specific DT applications in government, health, education, and economics. "Sustainable Energy" and "Supply Chain" have been identified as the most prominent topics in current DT processes and applications. This study can help researchers and practitioners in the field by providing insights and implications about the evolution and applications of DT. Our findings are intended to serve as a guide for DT in understanding current research gaps and potential future research topics.Article Citation - WoS: 2Citation - Scopus: 2Performance Assessment of Anion Exchange Electrolyzer With PBI-BASED Membrane Through 0-D Modeling(Elsevier Ltd, 2025) Celebi, Ceren; Colpan, C. Ozgur; Devrim, YilserAnion exchange membrane (AEM) water electrolysis is emerging as a promising method for the sustainable production of hydrogen. A key advantage lies in the potential for cost-effective hydrogen production by substituting expensive noble metal electrocatalysts with affordable transition metals. This work presents a 0-D mathematical model for evaluating the performance of AEMWEs, with a particular focus on polybenzimidazole (PBI)-based membranes, which are renowned for their high thermal stability, chemical resistance and excellent conductivity in alkaline media. The objective of the model is to predict the behavior of membranes in AEMWE systems, and it has been employed to evaluate the performance of a range of PBI membranes. To ensure precision, the values were meticulously selected from the literature, in accordance with the experimental conditions. Furthermore, IR-corrected validation was incorporated to isolate the impact of membrane conductivity on performance, thereby facilitating a dependable assessment of PBI membranes under diverse conditions. The model considers the effects of electrolyte resistance and bubble formation on cell voltage behavior. The efficiency was evaluated on the basis of the higher heating value (HHV). The findings demonstrate that one membrane exhibits consistent efficiency across a broad temperature range (40-90 degrees C), whereas the other displays notable variability under diverse conditions. In particular, the efficiency of the electrolyzer is significantly enhanced by the use of thinner membranes and higher temperatures. The highest efficiencies obtained were 83.9% and 79.8% for 25 mu m and 50 mu m PBI/Polystyrene membrane under the operating conditions of 1 M KOH solution at 80 degrees C and current density of 2 A/cm2. This study aims to provide valuable information on the performance of PBI membranes through a zero-dimensional model validated by experimental data.Article Citation - WoS: 2Citation - Scopus: 3Modeling of Kappa Factor Using Multivariate Adaptive Regression Splines: Application To the Western Türkiye Ground Motion Dataset(Springer, 2024) Kurtulmus, Tevfik Ozgur; Yerlikaya-Ozkurt, Fatma; Askan, Aysegul; Yerlikaya–Özkurt, FatmaThe recent seismic activity on Turkiye's west coast, especially in the Aegean Sea region, shows that this region requires further attention. The region has significant seismic hazards because of its location in an active tectonic regime of North-South extension with multiple basin structures on soft soil deposits. Recently, despite being 70 km from the earthquake source, the Samos event (with a moment magnitude of 7.0 on October 30, 2020) caused significant localized damage and collapse in the Izmir city center due to a combination of basin effects and structural susceptibility. Despite this activity, research on site characterization and site response modeling, such as local velocity models and kappa estimates, remains sparse in this region. Kappa values display regional characteristics, necessitating the use of local kappa estimations from previous earthquake data in region-specific applications. Kappa estimates are multivariate and incorporate several characteristics such as magnitude and distance. In this study, we assess and predict the trend in mean kappa values using three-component strong-ground motion data from accelerometer sites with known VS30 values throughout western Turkiye. Multiple linear regression (MLR) and multivariate adaptive regression splines (MARS) were used to build the prediction models. The effects of epicentral distance Repi, magnitude Mw, and site class (VS30) were investigated, and the contributions of each parameter were examined using a large dataset containing recent seismic activity. The models were evaluated using well-known statistical accuracy criteria for kappa assessment. In all performance measures, the MARS model outperforms the MLR model across the selected sites.Article Citation - WoS: 11Citation - Scopus: 14Protective Effects of BPC 157 on Liver, Kidney, and Lung Distant Organ Damagein Rats with Experimental Lower-Extremity Ischemia–Reperfusion Injury(MDPI, 2025) Demirtas, Hueseyin; Ozer, Abdullah; Yildirim, Alperen Kutay; Dursun, Ali Dogan; Sezen, Saban Cem; Arslan, MustafaBackground and Objectives: Ischemia–reperfusion (I/R) injury can affect multiple distant organs following I/R in the lower extremities. BPC-157’s anti-inflammatory and free radical-neutralizing properties suggest its potential in mitigating ischemia–reperfusion damage. This study evaluates the protective effects of BPC-157 on remote organ damage, including the kidneys, liver, and lungs, in a rat model of skeletal muscle I/R injury. Materials and Methods: A total of 24 male Wistar albino rats were randomly divided into four groups: sham (S), BPC-157(B), lower extremity I/R(IR) and lower extremity I/R+BPC-157(I/RB). Some 45 min of ischemia of lower extremity was followed by 2 h of reperfusion of limbs. BPC-157 was applied to groups B and I/RB at the beginning of the procedure. After 2 h of reperfusion, liver, kidney and lung tissues were harvested for biochemical and histopathological analyses. Results: In the histopathological examination, vascular and glomerular vacuolization, tubular dilation, hyaline casts, and tubular cell shedding in renal tissue were significantly lower in the I/RB group compared to other groups. Lung tissue showed reduced interstitial edema, alveolar congestion, and total damage scores in the I/RB group. Similarly, in liver tissue, sinusoidal dilation, necrotic cells, and mononuclear cell infiltration were significantly lower in the I/RB group. Additionally, the evaluation of TAS, TOS, OSI, and PON-1 revealed a statistically significant increase in antioxidant activity in the liver, lung, and kidney tissues of the I/RB group. Conclusions: The findings of this study demonstrate that BPC-157 exerts a significant protective effect against distant organ damage in the liver, kidneys, and lungs following lower extremity ischemia–reperfusion injury in rats.Article Citation - WoS: 9Citation - Scopus: 9Dft Insights Into Noble Gold-Based Compound Li5aup2: Effect of Pressure on Physical Properties(Amer Chemical Soc, 2023) Surucu, Gokhan; Gencer, Aysenur; Surucu, Ozge; Ali, Md. AshrafIn this study, the Li5AuP2 compound is investigated in detail due to the unique chemical properties of gold that are different from other metals. Pressure is applied to the compound from 0 to 25 GPa to reveal its structural, mechanical, electronic, and dynamical properties using density functional theory (DFT). Within this pressure range, the compound is optimized with a tetragonal crystal structure, making it mechanically and dynam-ically stable above 18 GPa and resulting in an increment of bulk, shear, and Young's moduli of Li5AuP2. Pressure application, furthermore, changes the brittle or ductile nature of the compound. The anisotropic elastic and sound wave velocities are visualized in three dimensions. The thermal properties of the Li5AuP2 compound are obtained, including enthalpy, free energy, entropy x T, heat capacity, and Debye temperature. The electronic properties of the Li5AuP2 compound are studied using the Perdew-Burke-Ernzerhof (PBE) and Heyd-Scuseria-Ernzerhof (HSE) functionals. The pressure increment is found to result in higher band gap values. The Mulliken and bond overlap populations are also determined to reveal the chemical nature of this compound. The optical properties, such as dielectric functions, refractive index, and energy loss function of the Li5AuP2 compound, are established in detail. To our knowledge, this is the first attempt to study this compound in such detail, thus, making the results obtained here beneficial for future studies related to the chemistry of gold.Article On the Injectivity With Respect To q of the Lupas q-transform(Taylor & Francis Ltd, 2024) Yilmaz, Ovgue Gurel; Ostrovska, Sofiya; Turan, Mehmet; Gurel Yilmaz, OvguThe Lupas q-transform has first appeared in the study of the Lupas q-analogue of the Bernstein operator. Given 0 < q < 1 and f is an element of C[0, 1], the Lupas q-transform is defined by Lambda(q)(f; x) Pi(infinity)(k=0) 1/1 + q(k)x Sigma(k=0)f(1 - q(k))q(k(k-1)/2)x(k)/(1 - q)(1 - q(2)) center dot center dot center dot (1 - q(k)), x >= 0. During the last decades, this transform has been investigated from a variety of angles, including its analytical, geometric features, and properties of its block functions along with their sums. As opposed to the available studies dealing with a fixed value of q, the present work is focused on the injectivity of Lambda(q) with respect to parameter q. More precisely, the conditions on f such that equality Lambda(q)(f; x) = Lambda(r)(f; x); x >= 0 implies q = r have been established.