2 results
Search Results
Now showing 1 - 2 of 2
Article Evaluation of Clinical Characteristics, Risk Factors and Prognosis of Herpes Zoster (Shingles) Infection in Turkiye: Varicomp-Adult Study(Elsevier Sci Ltd, 2025) Ozgen-Top, Ozge; Karacaer, Zehra; Ozkan, Ece Firuze; Ozger, Hasan Selcuk; Saltoglu, Nese; Oztoprak-Cuvalci, Nefise; Senol, EsinObjective: The study aimed to determine the estimated prevalence of herpes zoster (HZ) infection in the adult population in Turkiye and the rates of HZ-associated complications and risk factors. Methods: This retrospective, multicenter ( n = 11), cross-sectional study was conducted between January 2016 and January 2022 and included all patients aged >= 18 years diagnosed with shingles following screening based on ICD-10 codes. The prevalence of HZ infection was calculated; rates of HZ-related complications (recurrence, hospitalization, postherpetic neuralgia [PHN]) and associated risk factors were determined. Results: A total of 6114 HZ patients were included; the estimated 5-year HZ prevalence in Turkiye was 908.7 per 10 0,0 0 0 population. Of the patients, 851 (14.2%) were immunocompromised, 366 (6%) were hospitalized due to HZ, 284 (8.9%) experienced PHN, 97 (3.2%) experienced recurrence of the patients. Risk factors for PHN were older age ( >= 50 years [OR = 3.19; P < 0.001)], and trigeminal dermatome involvement (OR = 2.45; P = 0.006). Antiviral use was associated with reduced PHN risk (OR = 0.16; P < 0.001). Conclusions: Our multicenter cross-sectional study revealed the high burden of HZ in Turkiye and high-lighted the potential for increasing prevalence due to risk factors including aging and comorbidities. (c) 2025 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)Article Herpes Zoster Hastalarının Demografik ve Klinik Özelliklerinin Değerlendirilmesi(Selcuk University, 2023) Demirci Saadet, E.; Hasanbeyzade, S.Background: Herpes zoster is a disease that is more frequently seen in people aged over 50 years and negatively affects the quality of life due to the development of post-herpetic neuralgia. This study aimed to investigate the demographic and clinical characteristics of patients diagnosed with herpes zoster. Methods: In this cross-sectional study, the data of patients who were followed up with a diagnosis of herpes zoster at the dermatology department between 2013 and 2020 were retrospectively examined. Results: Of 440 patients, 252 (57.3%) were female and 188 (42.7%) were male. The mean age was 48.9±18 (4-94) years. The most common localization was the thoracic region at a rate of 35.5% and the lumbar region at a rate of 21.4%. Disseminated and ophthalmic zoster were more common in elderly patients (p<0.001). The most common comorbidities were hypertension (HT)+coronary artery disease (CAD) (12.6%), cancer (10.3%), and diabetes+HT (5.9%). Severe pain was observed in 19.7% of the patients and was more common in women (p=0.016). The rate of moderate and severe pain was high in the patients with HT+CAD and cancer (p˂0.001). Post-herpetic neuralgia was observed in 15.3% of the patients aged over 50. Conclusions: Herpes zoster is especially common in adults. Since it causes acute pain and can lead to postherpetic neuralgia development, risky patient groups should be more carefully followed up and treated. © 2023, Selcuk University. All rights reserved.
