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Review Citation - WoS: 75Citation - Scopus: 120Hybrid Blockchain Platforms for the Internet of Things (iot): a Systematic Literature Review(Mdpi, 2022) Alkhateeb, Ahmed; Catal, Cagatay; Kar, Gorkem; Mishra, AlokIn recent years, research into blockchain technology and the Internet of Things (IoT) has grown rapidly due to an increase in media coverage. Many different blockchain applications and platforms have been developed for different purposes, such as food safety monitoring, cryptocurrency exchange, and secure medical data sharing. However, blockchain platforms cannot store all the generated data. Therefore, they are supported with data warehouses, which in turn is called a hybrid blockchain platform. While several systems have been developed based on this idea, a current state-of-the-art systematic overview on the use of hybrid blockchain platforms is lacking. Therefore, a systematic literature review (SLR) study has been carried out by us to investigate the motivations for adopting them, the domains at which they were used, the adopted technologies that made this integration effective, and, finally, the challenges and possible solutions. This study shows that security, transparency, and efficiency are the top three motivations for adopting these platforms. The energy, agriculture, health, construction, manufacturing, and supply chain domains are the top domains. The most adopted technologies are cloud computing, fog computing, telecommunications, and edge computing. While there are several benefits of using hybrid blockchains, there are also several challenges reported in this study.Review Citation - WoS: 120Citation - Scopus: 142Dynamic Thermal and Hygrometric Simulation of Historical Buildings: Critical Factors and Possible Solutions(Pergamon-elsevier Science Ltd, 2020) Akkurt, G. G.; Aste, N.; Borderon, J.; Buda, A.; Calzolari, M.; Chung, D.; Turhan, C.Building dynamic simulation tools, traditionally used to study the hygrothermal performance of new buildings during the preliminary design steps, have been recently adopted also in historical buildings, as a tool to investigate possible strategies for their conservation and the suitability of energy retrofit scenarios, according to the boundary conditions. However, designers often face with the lack of reliable thermophysical input data for various envelope components as well as with some intrinsic limitations in the simulation models, especially to describe the geometric features and peculiarities of the heritage buildings. This paper attempts to bridge this knowledge gap, providing critical factors and possible solutions to support hygrothermal simulations of historical buildings. The information collected in the present work could be used by researchers, specialists and policy-makers involved in the conservation of building's heritage, who need to address a detailed study of the hygrothermal performance of historical buildings thorugh dynamic simulation tools.Review Citation - WoS: 10Citation - Scopus: 10Latest Developments in Engineered Skeletal Muscle Tissues for Drug Discovery and Development(Taylor & Francis Ltd, 2023) Ostrovidov, Serge; Ramalingam, Murugan; Bae, Hojae; Orive, Gorka; Fujie, Toshinori; Shi, Xuetao; Kaji, HirokazuIntroductionWith the advances in skeletal muscle tissue engineering, new platforms have arisen with important applications in biology studies, disease modeling, and drug testing. Current developments highlight the quest for engineering skeletal muscle tissues with higher complexity . These new human skeletal muscle tissue models will be powerful tools for drug discovery and development and disease modeling.Areas coveredThe authors review the latest advances in in vitro models of engineered skeletal muscle tissues used for testing drugs with a focus on the use of four main cell culture techniques: Cell cultures in well plates, in microfluidics, in organoids, and in bioprinted constructs. Additional information is provided on the satellite cell niche.Expert opinionIn recent years, more sophisticated in vitro models of skeletal muscle tissues have been fabricated. Important developments have been made in stem cell research and in the engineering of human skeletal muscle tissue. Some platforms have already started to be used for drug testing, notably those based on the parameters of hypertrophy/atrophy and the contractibility of myotubes. More developments are expected through the use of multicellular types and multi-materials as matrices . The validation and use of these models in drug testing should now increase.Review Anlaşılabilir Girdinin Muğlak Tanımı ve “edinme” Teriminin Yanıltıcı Kullanımı Üzerine Eleştirel Bir İnceleme(2020) Peker, Hilal; Özkaynak, OnurStephen Krashen, ikinci dil edinimi alanında önde gelen isimlerden biri olmuştur. Girdi Hipotezi ve Monitör Modeli en dikkat çekici eseri olarak düşünülebilir. Özellikle, dil edinimi için anlaşılabilir girdinin önemini vurgulayan temel önerisi dil yeterliliğine önemli oranda ışık tutmuştur. Krashen, dil edinen kişiye doğal dil parçaları sağlandığı sürece dillerin kolayca edinilebileceğini iddia etmiştir. Aldığı büyük beğeniye rağmen, Krashen’in fikirleri, bazı dilbilimciler tarafından sert bir şekilde eleştirilmiştir, çünkü Krashen’in iddiaları ikinci dil edinimi ile ilgili belli başlı bazı konuları netleştirememiştir. Bu bağlamda, bu makalenin yazarları, Girdi Hipotezi ve Monitör Modelini dil edinimi için girdinin yetersizliği, anlaşılabilir girdinin operasyonel bir tanımının bulunmaması ve edinim teriminin yanıltıcı kullanımı gibi konulara odaklanan eleştirel bir şekilde gözden geçirmektedir. Buna ek olarak, yazarlar, yukarıda belirtilen yetersizlikleri ve yanıltıcı unsurlara dikkat çekmek için iddialarını dil bilimi alanında günümüzde nadir olarak yapılmış deneysel ve bilimsel çalışmalarla desteklerken hicivli bir dili benimsemişlerdir.Review Citation - WoS: 7Citation - Scopus: 9A Survey of Covid-19 Diagnosis Using Routine Blood Tests With the Aid of Artificial Intelligence Techniques(Mdpi, 2023) Habashi, Soheila Abbasi; Koyuncu, Murat; Alizadehsani, RoohallahSevere Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), causing a disease called COVID-19, is a class of acute respiratory syndrome that has considerably affected the global economy and healthcare system. This virus is diagnosed using a traditional technique known as the Reverse Transcription Polymerase Chain Reaction (RT-PCR) test. However, RT-PCR customarily outputs a lot of false-negative and incorrect results. Current works indicate that COVID-19 can also be diagnosed using imaging resolutions, including CT scans, X-rays, and blood tests. Nevertheless, X-rays and CT scans cannot always be used for patient screening because of high costs, radiation doses, and an insufficient number of devices. Therefore, there is a requirement for a less expensive and faster diagnostic model to recognize the positive and negative cases of COVID-19. Blood tests are easily performed and cost less than RT-PCR and imaging tests. Since biochemical parameters in routine blood tests vary during the COVID-19 infection, they may supply physicians with exact information about the diagnosis of COVID-19. This study reviewed some newly emerging artificial intelligence (AI)-based methods to diagnose COVID-19 using routine blood tests. We gathered information about research resources and inspected 92 articles that were carefully chosen from a variety of publishers, such as IEEE, Springer, Elsevier, and MDPI. Then, these 92 studies are classified into two tables which contain articles that use machine Learning and deep Learning models to diagnose COVID-19 while using routine blood test datasets. In these studies, for diagnosing COVID-19, Random Forest and logistic regression are the most widely used machine learning methods and the most widely used performance metrics are accuracy, sensitivity, specificity, and AUC. Finally, we conclude by discussing and analyzing these studies which use machine learning and deep learning models and routine blood test datasets for COVID-19 detection. This survey can be the starting point for a novice-/beginner-level researcher to perform on COVID-19 classification.Review Citation - WoS: 23Controlled Gene Delivery Systems: Nanomaterials and Chemical Approaches(Amer Scientific Publishers, 2020) Ahmadi, Sepideh; Rabiee, Navid; Fatahi, Yousef; Bagherzadeh, Mojtaba; Gachpazan, Meysam; Baheiraei, Nafiseh; Hamblin, Michael R.Successful gene therapy depends on the design of effective gene delivery systems. A gene delivery system is considered a powerful tool for the release of genetic material within cells resulting in a change in cell functions and protein production. The release of genes in a controlled manner by using appropriate carriers facilitates their release without side effects and increases the expression of genes at the released site. It is expected that significant changes in the combination of several genes and drugs can be provided by developing treatment systems sensitive to different stimuli such as redox potential, pH variations, temperature gradients, light irradiation, and enzyme activity. The most important advantages for the release of genes and stimuli-responsive therapeutics include delivering vectors locally, reducing side effects and causing no toxicity to distant tissues while at the same time reducing the immune response to the vectors. In this review, we aim to discuss different types of gene carriers involved in the controlled transfer of nucleic acids (non-viral inorganic and organic nanoparticles (NPs) and virus-like particles (VLPs)) as well as the simultaneous transfer of several genes and/or drugs into cells or different tissues, providing for an efficient and safe treatment of numerous diseases.Review Citation - Scopus: 1Operetta in Turkey: A case study of Gün’s translation of Strauss’s Die Fledermaus(John Benjamins Publishing Company, 2020) Soy,Ö.Ş.; Şenol,M.The genre operetta has long found itself a place in the musical polysystem of Turkey and become one of the borrowed forms of art symbolizing modernity through Turkey’s Westernization process. It was the main goal of the Republic to carry the young republican nation to the level of civilized societies like those of the West. Western ideological, cultural, scientific and literary works were examined and translated, paving the way to emergence of national ideologies, literary works, and cultural legacies. In this context, our study aims to examine Aydın Gün’s translation into Turkish of Johann Strauss II’s Die Fledermaus, under the title Yarasa. In order to do this, we draw on Peter Low’s Pentathlon Principle. © 2020 John Benjamins Publishing Company.Review Analysis of Different Methods of Suppressing Generator Noise Reaching Indoor Noise(2022) Öz, Hatice Mehtap; Koçyiğit, Filiz Bal; Köse, ErcanThe noise which occurs during the operation of the auxiliary power units is a disturbing factor, although its level varies depending on the environment. This high level of noise in occupational areas can cause not only health but also accidents risks. While silencers are mostly preferred for active noise control, acoustic foam or textile products are preferred according to passive control methods. In this review, the noises produced by the generators were examined and the studies in the literature on suppressing these noises were evaluated by making comparative analyzes. New recommendations have been developed according to the results of the comparative analysis. In case the sampled natural gas generator is closed with 2 mm thick plywood and a steel framed box covered with an acoustic sponge, the sound pressure level is approximately 30 dB in low frequency diesel + electric generators using a silencer according to active control methods. In measurements; It was observed that it decreased from 93.2 to 88.4 dB. While materials such as an acoustic sponge, which are preferred in passive control methods, are open-celled and porous structures, it is advantageous to have sound absorption capacity, but it can be a disadvantage due to its synthetic content.Review Citation - WoS: 22Citation - Scopus: 36Principles of Reverse Electrodialysis and Development of Integrated-Based System for Power Generation and Water Treatment: a Review(Walter de Gruyter Gmbh, 2022) Othman, Nur Hidayati; Kabay, Nalan; Guler, EnverReverse electrodialysis (RED) is among the evolving membrane-based processes available for energy harvesting by mixing water with different salinities. The chemical potential difference causes the movement of cations and anions in opposite directions that can then be transformed into the electrical current at the electrodes by redox reactions. Although several works have shown the possibilities of achieving high power densities through the RED system, the transformation to the industrial-scale stacks remains a challenge particularly in understanding the correlation between ion-exchange membranes (IEMs) and the operating conditions. This work provides an overview of the RED system including its development and modifications of IEM utilized in the RED system. The effects of modified membranes particularly on the psychochemical properties of the membranes and the effects of numerous operating variables are discussed. The prospects of combining the RED system with other technologies such as reverse osmosis, electrodialysis, membrane distillation, heat engine, microbial fuel cell), and flow battery have been summarized based on open-loop and closed-loop configurations. This review attempts to explain the development and prospect of RED technology for salinity gradient power production and further elucidate the integrated RED system as a promising way to harvest energy while reducing the impact of liquid waste disposal on the environment.Review Sivil Havacılıkta Elektrikli Yer Hizmetleri Teçhizatı Kullanımı Faydalar, Kısıtlar ve Öneriler(2020) Yıldız, Melih; Mutlu, SavaşHavacılık sektörü, her yıl gösterdiği yüksek büyüme oranları yanı sıra, çevre vesağlık sorunlarına neden olan emisyonları azaltmak ve akaryakıt ile işletmemaliyelerini düşürmek için gayret göstermektedir. Bu çabaların ortak paydasındabulunan tahrik sistemlerinde elektrik enerjisi kullanımı giderek ilgi çekmektedir.Bir yandan da yetkili otoritelerin elektrikli araç kullanımı konusundaki yaklaşımısonucu, havacılık ekosisteminin önemli unsurlarından biri olan yer hizmetlerindekullanılan teçhizatın da elektrikli alternatifleri gündeme gelmiştir. Bu araştırmada,yer hizmetlerinde kullanılan teçhizatın elektrikli olmasındaki faydalar ile birliktesöz konusu teçhizatın kısıtları ve konu hakkındaki öneriler ortaya konulmuştur.Araştırma nitel olarak gerçekleştirilmiş ve ikincil verilerden faydalanılmıştır.Araştırmada dünyada bu alanda yapılmış uygulama çalışmalarından elde edilendeneyim ve modelleme çalışmaları sonuçları analiz edilmiş, bu alandaki genel eğilimortaya konulmuştur. Ülkemizde önde gelen firmalardan birisinin mevcut elektrikliyer hizmetleri teçhizatı kullanım oranları değerlendirilmiştir. Ülkemiz elektrikli yerhizmetleri teçhizatı kullanımının incelenen ülkeler ortalamasında olduğugörülmüştür. Çalışma sonucunda elektrikli yer hizmetleri teçhizatınınyaygınlaşması için gerekli şartlar belirlenmiş ve öneriler oluşturulmuştur.

