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Article Citation - WoS: 11Citation - Scopus: 15A Study on the Performance Evaluation of Wavelet Decomposition in Transient-Based Radio Frequency Fingerprinting of Bluetooth Devices(Wiley, 2022) Almashaqbeh, Hemam; Dalveren, Yaser; Kara, AliRadio frequency fingerprinting (RFF) is used as a physical-layer security method to provide security in wireless networks. Basically, it exploits the distinctive features (fingerprints) extracted from the physical waveforms emitted from radio devices in the network. One of the major challenges in RFF is to create robust features forming the fingerprints of radio devices. Here, dual-tree complex wavelet transform (DT-CWT) provides an accurate way of extracting those robust features. However, its performance on the RFF of Bluetooth transients which fall into narrowband signaling has not been reported yet. Therefore, this study examines the performance of DT-CWT features on the use of transient-based RFF of Bluetooth devices. Initially, experimentally collected Bluetooth transients from different smartphones are decomposed by DT-CWT. Then, the characteristics and statistics of the wavelet domain signal are exploited to create robust features. Next, the support vector machine (SVM) is used to classify the smartphones. The classification accuracy is demonstrated by varying channel signal-to-noise ratio (SNR) and the size of transient duration. Results show that reasonable accuracy can be achieved (lower bound of 88%) even with short transient duration (1024 samples) at low SNRs (0-5 dB).Article Citation - WoS: 1Citation - Scopus: 1Personal Response Systems Through the Prism of Students' Experiences(Wiley, 2020) Mishra, Deepti; Chew, Esyin; Ostrovska, Sofiya; Wong, JojoPersonal response systems (PRSs) today offer an opportunity to the field of education in terms of improving teaching and learning outcomes through active engagement in classrooms. The present paper investigates students' attitudes to different types of PRSs, namely, Socrative and Clickers. Both qualitative and quantitative data are gathered and classified. The performed thematic analysis reveals major categories within the framework of this study, namely educational efficacy, psychological aspects, technology-related issues, and administrative issues. It has been found that Socrative fares better in the "educational efficacy" and "administrative issues," whereas Clickers outperforms Socrative in the "technological-related issues." It is worth pointing out that both Socrative and Clickers are tantamount in "psychological aspects" yielding no negative experiences. The results of this study reveal that two main factors, cost and technological infrastructure, are determinative in the incorporation and appreciation of such systems in an educational setting.Article Citation - WoS: 17Citation - Scopus: 30Analysis of Cultural and Gender Influences on Teamwork Performance for Software Requirements Analysis in Multinational Environments(Wiley, 2012) Fernandez-Sanz, L.; Misra, SanjaySoftware development is mainly a social activity where teams of developers should work as a coordinated unit to fulfill the needs of customers. Studies have shown the importance of teamwork ability as the main skill for software professionals both in local settings and in global software development. Teamwork performance can be evaluated according to different approaches but we need deeper analysis within software teams of differences in individuals' performance related to culture, nationality or even gender. We applied a simple evaluation experience named teamwork benefits awareness (TBA) to groups of last-year students of computing degrees with experience as junior IT professionals during intensive multinational workshops based on international software projects. TBA allowed to measure individual and team performance during a requirements analysis session based on a real project. Results segmented by nationality and gender are presented and analysed in comparison with the data collected from computing professionals in local settings. In general, no significant differences have been found out although interesting relations are suggested with two Hofstede's country indicators. TBA is also perceived as a good technique for highlighting both teamwork benefits as well as the nature of real situations of software requirements analysis and orientation to customer needs.Article Citation - WoS: 4Citation - Scopus: 6A Team-Oriented Course Development Experience in Distance Education for Multidisciplinary Engineering Design(Wiley, 2022) Say, Bilge; Erden, Zühal; Erden, Zuhal; Turhan, Cihan; Turhan, Cihan; Say, Bilge; Erden, Zühal; Turhan, Cihan; Say, Bilge; Energy Systems Engineering; Software Engineering; Mechatronics Engineering; Energy Systems Engineering; Mechatronics Engineering; Software EngineeringBased on the multidisciplinary needs of today's complex and innovative technology, accreditation bodies of engineering demand proof of multidisciplinary teamwork in undergraduate engineering curricula. This article reports the design and conduct of a Multidisciplinary Engineering Design (MED) course initiated as a result of accreditation process requirements. The course, which consists of multidisciplinary lectures, practice sessions, and various phases of a multidisciplinary team project, was conducted online because of the COVID-19 pandemic by a multidisciplinary team of instructors using multiple software tools to enhance collaboration. In general, the course outcomes were satisfied under the current design, and several points for further improvement and elaboration were collected via quantitative and qualitative evaluations. Accordingly, the results show that the project-based and team-based MED course, in terms of multidisciplinary course management and its outcomes, can benefit from the use of software tools in creating a multidisciplinary team in distance education by means of enhanced cooperation and motivation among the participants.Article Citation - WoS: 19Citation - Scopus: 20The consumers' social media use in choosing physicians and hospitals: the case study of the province of Izmir(Wiley, 2017) Tengilimoglu, Dilaver; Sarp, Nilgn; Yar, Cemre Eda; Bektas, Meral; Hidir, Mehmet Nil; Korkmaz, EsinManifested as a reflection of the Internet technology progress, web 2.0 has transformed communication among people to different dimensions while increasing the social use of Internet. Thus, the concept of social media has entered our lives. Blogs, forums, Facebook, Twitter and YouTube applications are but few of the social media platforms with active users exceeding millions. As in many other subjects, these and others are also environments where people share information and their positive or negative experiential views with respect to healthcare issues and services. Hence, the social media communication and exchange of information are deemed influential on the process of receiving health services. In the present study that aims to determine social media use of individuals in their choice of physicians, dentists and hospitals, a survey, as a data collection instrument, has been carried out to 947 residents of the province of Izmir. Individuals participating in the study have stated that they have used social media in choosing a physician (41.9% of the participants), dentist (34.1% of the participants) and hospitals (41.7% of the participants). The study has revealed that individuals are affected by social media in their healthcare choices. Copyright (C) 2015 John Wiley & Sons, Ltd.Article Citation - WoS: 7Citation - Scopus: 6A platinum blue complex exerts its cytotoxic activity via DNA damage and induces apoptosis in cancer cells(Wiley, 2017) Adiguzel, Zelal; Ozalp-Yaman, Seniz; Celik, Gokalp; Salem, Safia; Bagci-Onder, Tugba; Senbabaoglu, Filiz; Acilan, CeydaHere, we describe the characteristics of a Pt-blue complex [Pt-4(2-atp)(8)(H2O)(OH)] (2-atp: 2-aminothiophenol) as a prodrug for its DNA-binding properties and its use in cancer therapy. The nature of the interaction between the Pt-blue complex and DNA was evaluated based on spectroscopic measurements, the electronic absorption spectra, thermal behavior, viscosity, fluorometric titration, and agarose gel electrophoresis. Our results suggested that the compound was able to partially intercalate DNA and appeared to induce both single- and double-stranded breaks (DBS) on DNA in vitro, but no DSBs in cells. The ability of the compound to induce DNA damage was dependent on reactive oxygen species (ROS) in vitro. There was also elevated formation of ROS and SOD expression in response to drug treatment in cell culture. The complex was found to be more cytotoxic to cancer cells in comparison with noncancer controls using WST-1 assay. The mean of cell death was determined to be apoptosis as assessed via biochemical, morphological, and molecular observations, including DNA condensation/fragmentation analysis, live cell imaging microscopy, TUNEL analyses, and increase in the levels of pro-apoptotic genes such as Bag3, Bak, Bik, Bmf, and Hrk. Hence, the Pt-blue complex under study grants premise for further studies.Article Citation - WoS: 139Citation - Scopus: 140CaXH3 (X = Mn, Fe, Co) perovskite-type hydrides for hydrogen storage applications(Wiley, 2020) Surucu, Gokhan; Gencer, Aysenur; Candan, Abdullah; Gullu, Hasan H.; Isik, MehmetHydrogen storage is one of the attractive research interests in recent years due to the advantages of hydrogen to be used as energy source. The studies on hydrogen storage applications focus mainly on investigation of hydrogen storage capabilities of newly introduced compounds. The present paper aims at characterization of CaXH3 (X: Mn, Fe, or Co) perovskite-type hydrides for the first time to understand their potential contribution to the hydrogen storage applications. CaXH3 compounds have been investigated by density functional theory studies to reveal their various characteristics and hydrogen storage properties. CaXH3 compounds have been optimized in cubic crystal structure and the lattice constants of studied compounds have been obtained as 3.60, 3.50, and 3.48 angstrom for X: Mn, Fe, and Co compounds, respectively. The optimized structures have negative formation enthalpies pointing out that studied compounds are thermodynamically stable and could be synthesized experimentally. The gravimetric hydrogen storage densities of X: Mn, Fe, and Co compounds were found in as 3.09, 3.06, and 2.97 wt%, respectively. The revealed values for hydrogen storage densities indicate that CaXH3 compounds may be potential candidates for hydrogen storage applications. Moreover, various mechanical parameters of interest compounds like elastic constants, bulk modulus, and Poisson's ratio have been reported throughout the study. These compounds were found mechanically stable with satisfying Born stability criteria. Further analyses based on Cauchy pressure and Pugh criterion, showed that they have brittleness nature and relatively hard materials. In addition, the electronic characteristics, band structures, and associated partial density of states of CaXH3 hydrides have been revealed. The dynamic stability behavior of them was verified based on the phonon dispersion curves.Article Enhanced Doxorubicin Cytotoxicity on Breast Cancer Spheroids by Aptamer Targeted Co-Delivery With Hyaluronidase(Wiley, 2025) Kavruk, Murat; Demirel, Dide Su; Bonyadi, Farzaneh; Guner, Buket Cakmak; Dursun, Ali Dogan; Vakifahmetoglu, Cekdar; Ozalp, Veli CengizBreast cancer is one of the most prevalent solid tumors in women and can be classified into subtypes based on molecular characteristics, such as hormone receptor status and HER2 expression. Aptamers, highly specific affinity molecules, are extensively studied for targeted drug delivery using nanocarriers to enhance anti-cancer efficacy. This study focused on HER2-responsive co-delivery of doxorubicin and hyaluronidase via aptamer-gated mesoporous silica nanoparticles to improve therapeutic outcomes in solid tumors. SK-BR-3 spheroids are employed as a model for resistant tumor environments in solid tumors. Previous research is shown that conjugating cytotoxic drugs with nanoparticles or cells enhances drug penetration into tumor spheroids. In this work, doxorubicin is loaded into mesoporous silica nanoparticles and capped with HER2-specific aptamers, while the particle surface is functionalized with hyaluronidase. This dual-functionalized nanocarrier system achieves an approximate to 8.5-fold increase in cytotoxicity compared to aptamer-targeted delivery lacking hyaluronidase. The enhanced effect is attributed to hyaluronidase-mediated loosening of the spheroid structure, facilitating nanoparticle penetration and localized release of doxorubicin at high concentrations on HER2-positive cells.Article Information-Theoretic Approach in Allometric Scaling Relations of Dna and Proteins(Wiley, 2022) Adiguzel, YekbunAllometric scaling relations can be observed in between molecular parameters. Hence, we looked for presence of such relation among sizes (i.e., lengths) of proteins and genes. Protein lengths exist in the literature as the number of amino acids. They can also be derived from the mRNA lengths. Here, we looked for allometric scaling relation by using such data and simultaneously, the data was compared with the sizes of genes and proteins that were obtained from our modified information-theoretic approach. Results implied presence of scaling relation in the calculated results. This was expected due to the implemented modification in the information-theoretic calculation. Relation in the literature-based data was lacking high goodness of fit value. It could be due to physical factors and selective pressures, which ended up in deviations of the literature-sourced values from those in the model. Genome size is correlated with cell size. Intracellular volume, which is related to the DNA size, would require certain number of proteins, the sizes of which can therefore be correlated with the protein sizes. Cell sizes, genome sizes, and average protein and gene sizes, along with the number of proteins, namely the expression levels of the genes, are the physical factors, and the molecular factors influence those physical factors. The selective pressures on those can act through the connection between those physical factors and limit the dynamic ranges. Biological measures could be prone to such forces and are likely to deviate from expected models, regardless of the validity of assumptions, unless those are also implemented in the models. Yet, present discrepancies could be pointing at the need for model improvement, data imperfection, invalid assumptions, etc. Still, current work highlights possible use of information-theoretic approach in allometric scaling relations' studies.Letter Citation - WoS: 3Citation - Scopus: 3Global Robust Stability of Interval Delayed Neural Networks: Modified Approach(Wiley, 2009) Singh, VimalA criterion for the global robust stability of Hopfield-type delayed neural networks with the intervalized network parameters is presented. The criterion, which is derived by utilizing the idea of splitting the given interval into two intervals, is in the form of linear matrix inequality and, hence, computationally tractable. The criterion yields a less conservative condition compared with many recently reported criteria, as is demonstrated with an example. Copyright (C) 2008 John Wiley & Sons, Ltd.
