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Article Citation - WoS: 10Citation - Scopus: 12Space Efficiency of Tall Buildings in Singapore(Mdpi, 2024) Aslantamer, Ozlem Nur; Ilgin, Hueseyin EmreSpace efficiency in Singaporean tall buildings results from a complex interplay of historical, architectural, engineering, technological, socioeconomic, and environmental factors. The city-state's innovative and adaptive approach has enabled it to overcome the challenges associated with skyscraper construction, leading to the development of some of the most advanced and sustainable high-rise structures in the world. However, there is currently a lack of detailed analysis on space utilization in Singaporean high-rise buildings. This study addresses this gap by examining 63 cases. The main findings of this research: 1. Residential functions, central core layouts, and prismatic shapes are the most frequent. 2. Concrete material with a shear-walled frame system is the preferred structural choice. 3. Average spatial efficiency is 80%, and the core-to-GFA (Gross Floor Area) ratio averages 17%. These metrics vary from a minimum of 68% and 5% to a maximum of 91% and 32%, respectively. These insights offer valuable guidance for Singaporean construction professionals, particularly architects, helping them make informed design decisions for high-rise projects.Article Citation - WoS: 4Citation - Scopus: 3The Effect of Combined Hydrolyzed Type 2 Collagen, Methylsulfonylmethane, Glucosamine Sulfate and Chondroitin Sulfate Supplementation on Knee Osteoarthritis Symptoms(Baycinar Medical Publ-baycinar Tibbi Yayincilik, 2024) Ayhan, Fikriye Figen; Çoban, Ayşegül Demirci; Karasu, Ayça Utkan; Karaoğlan, Belgin; Çınar, Ece; Eyigör, Sibel; Dalyan, MeltemObjectives: This study aimed to evaluate the effects of the combined hydrolyzed type 2 collagen, methylsulfonylmethane (MSM), glucosamine sulfate (GS), and chondroitin sulfate (CS) supplement on knee pain intensity in patients with knee osteoarthritis (OA). Patients and methods: This multicenter, observational, noninterventional study included 98 patients (78 females, 20 males; mean age: 52.8±6.5 years; range, 40 to 64 years) who had Grade 1-3 knee OA between May 2022 and November 2022. The patients were prescribed the combination of hydrolyzed type 2 collagen, MSM, GS, and CS as a supplement for knee OA. The sachet form of the combined supplement containing 1250 mg hydrolyzed type 2 collagen, 750 mg MSM, 750 mg GS, and 400 mg CS was used once daily for two consecutive months. Patients were evaluated according to the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Visual Analog Scale (VAS)-pain, and Health Assessment Questionnaire (HAQ). Patients were scheduled to visit for follow-up four weeks (Visit 2) and eight weeks (Visit 3) after Visit 1 (baseline; day 0 of the study). Results: For the VAS-pain, WOMAC, WOMAC-subscale, and HAQ scores, the differences in improvement between the three visits were significant (p<0.001 for all). The patient compliance with the supplement was a median of 96.77%, both for Visit 2 and Visit 3. Conclusion: The combination of hydrolyzed type 2 collagen, MSM, GS, and CS for eight weeks in knee OA was considered an effective and safe nutritional supplement.

