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Review Citation - WoS: 91Citation - Scopus: 105Recommendations for Head and Neck Surgical Oncology Practice in a Setting of Acute Severe Resource Constraint During the Covid-19 Pandemic: an International Consensus(Elsevier Science inc, 2020) Mehanna, Hisham; Hardman, John C.; Shenson, Jared A.; Abou-Foul, Ahmad K.; Topf, Michael C.; AlFalasi, Mohammad; Holsinger, F. ChristopherThe speed and scale of the global COVID-19 pandemic has resulted in unprecedented pressures on health services worldwide, requiring new methods of service delivery during the health crisis. In the setting of severe resource constraint and high risk of infection to patients and clinicians, there is an urgent need to identify consensus statements on head and neck surgical oncology practice. We completed a modified Delphi consensus process of three rounds with 40 international experts in head and neck cancer surgical, radiation, and medical oncology, representing 35 international professional societies and national clinical trial groups. Endorsed by 39 societies and professional bodies, these consensus practice recommendations aim to decrease inconsistency of practice, reduce uncertainty in care, and provide reassurance for clinicians worldwide for head and neck surgical oncology in the context of the COVID-19 pandemic and in the setting of acute severe resource constraint and high risk of infection to patients and staff.Article Citation - WoS: 8Citation - Scopus: 10Current Account and Credit Growth: the Role of Household Credit and Financial Depth(Elsevier Science inc, 2020) Ekinci, Mehmet Fatih; Ekinci, Mehmet Fatih; Omay, Tolga; Omay, Tolga; Ekinci, Mehmet Fatih; Omay, Tolga; Economics; EconomicsUnderstanding the impact of financial variables on the current account balance is one of the priorities of academic literature and policymakers. Evidence from a broad panel of advanced and emerging countries shows that an increase in credit growth is associated with a significant deterioration in the current account balance. When we examine the roles of the components of credit, we find that an increase in household credit causes a significant decline in the current account balance, whereas an increase in business loans has no significant effect. Therefore, our findings indicate that the significant negative impact of credit growth on the current account balance is driven by household credit. Furthermore, we show that total and household credit growth rates have a stronger negative effect on the current account balance for lower levels of financial depth. Our results suggest that targeted policy measures that curb household credit growth might be more effective to reduce external imbalances particularly at the early stages of financial deepening.Article Citation - WoS: 5Citation - Scopus: 5Maternal Pain Management at Home in Children with Cancer: A Turkish Sample(Elsevier Science inc, 2020) Boztepe, Handan; Ay, Ayse; Akyuz, CananPurpose: The purpose of the present study was to examine maternal pain management in children with cancer and the associated factors. Design and methods: The present work is a descriptive and cross-sectional study. Data for the study were obtained from mothers of children in the age group of 0 to 18 years undergoing treatment for solid tumors in Pediatric Oncology Service and Outpatient Clinics (n = 112 ). We used a questionnaire on parental pain management practices at home, the knowledge about pain and analgesic drugs, Spielberger State-Trait Anxiety Inventory (STAI), and Pain Catastrophizing Scale (PCS) to collect the data. Results: Several mothers taking part in the study reported various misconceptions about the assessment of children's pain, analgesic drugs, and usage of limited non-pharmacological methods for managing pain in children with cancer. No significant relationships were found between mothers' pain management practices, knowledge of pain assessment and analgesic drugs, and mothers' and children's sociodemographic characteristics or mothers' pain catastrophizing and anxiety about their own pain. Conclusions: The findings of the study revealed that the majority of mothers of children with cancer had misconceptions regarding knowledge of pain assessment and analgesic drugs; these misconceptions potentially lead to manage children's pain associated with cancer ineffectively. Findings indicate mothers' information and support needs for children's cancer pain management in the home settings. Practice implications: A further understanding of barriers to parental pain management in children with cancer in the home setting will contribute immensely in developing appropriate management practices. (C) 2019 Elsevier Inc. All rights reserved.Review Citation - WoS: 22Citation - Scopus: 28The Effect of £6 Cm Sized Noncavity-Distorting Intramural Fibroids on in Vitro Fertilization Outcomes: a Systematic Review and Meta-Analysis(Elsevier Science inc, 2023) Erden, Murat; Uyanik, Esra; Polat, Mehtap; Ozbek, Irem Yarali; Yarali, Hakan; Mumusoglu, SezcanImportance: The potential detrimental effects of fibroids on natural fecundity and in vitro fertilization (IVF) outcomes may be influ-enced by their size, location, and number. The impact of small noncavity-distorting intramural fibroids on reproductive outcomes in IVF is still controversial, with conflicting results.Objective(s): To determine whether women with noncavity-distorting intramural fibroids of & LE;6 cm size have lower live birth rates (LBRs) in IVF than female age-matched controls with no fibroids.Data Sources: MEDLINE, Embase, Global Health, and Cochrane Library databases were searched from inception until July 1, 2022. Study Selection and Synthesis: Women undergoing IVF with noncavity-distorting intramural fibroids & LE;6 cm constituted the study group (n = 520), whereas women with no fibroid formed the controls (n = 1392). Female age-matched subgroup analyses were performed to evaluate the impact of different cut-offs for size (& LE;6, & LE;4, and & LE;2 cm), location (the International Federation of Gynecology and Obstetrics [FIGO] type-3), and the number of fibroids on reproductive outcomes. Mantel-Haenszel odds ratios (ORs) with 95% confidence intervals (CIs) were used for outcome measures. All statistical analyses were performed using RevMan 5.4.1Main Outcome Measure(s): The primary outcome measure was LBR. Secondary outcome measures were clinical pregnancy, implan-tation, and miscarriage rates.Result(s): After adopting the eligibility criteria, 5 studies were included in the final analysis. Women with & LE;6 cm noncavity-distorting intramural fibroids had significantly lower LBRs (OR: 0.48, 95% CI: 0.36-0.65, 3 studies, I2=0; low-certainty evidence) compared with women with no fibroids. A significant reduction in LBRs was noted in & LE;4 cm but not in the & LE;2 cm subgroups. The FIGO type-3 fibroids of 2-6 cm size were associated with significantly lower LBRs. Owing to a lack of studies, the impact of the number of noncavity-distorting intramural fibroids (single vs. multiple) on IVF outcomes could not be assessed.Conclusion(s): We conclude that 2-6 cm sized noncavity-distorting intramural fibroids have a deleterious effect on LBRs in IVF. The presence of FIGO type-3 fibroids of 2-6 cm size is associated with significantly lower LBRs. Conclusive evidence from high-quality randomized controlled trials, the reference standard study design for studies of health care interventions, is needed before myomectomy might be offered in daily clinical practice to women with such small fibroids before undergoing IVF treatment. (Fertil Sterile 2023;119:996-1007. & COPY;2023 by American Society for Reproductive Medicine.)El resumen esta disponible en Espanol al final del articulo.Article Citation - WoS: 3Citation - Scopus: 5Global Energy Preserving Model Reduction for Multi-Symplectic Pdes(Elsevier Science inc, 2023) Uzunca, Murat; Karasozen, Bulent; Aydin, AyhanMany Hamiltonian systems can be recast in multi-symplectic form. We develop a reduced -order model (ROM) for multi-symplectic Hamiltonian partial differential equations (PDEs) that preserves the global energy. The full-order solutions are obtained by finite difference discretization in space and the global energy preserving average vector field (AVF) method. The ROM is constructed in the same way as the full-order model (FOM) applying proper orthogonal decomposition (POD) with the Galerkin projection. The reduced-order system has the same structure as the FOM, and preserves the discrete reduced global energy. Ap-plying the discrete empirical interpolation method (DEIM), the reduced-order solutions are computed efficiently in the online stage. A priori error bound is derived for the DEIM ap-proximation to the nonlinear Hamiltonian. The accuracy and computational efficiency of the ROMs are demonstrated for the Korteweg de Vries (KdV) equation, Zakharov-Kuznetzov (ZK) equation, and nonlinear Schrodinger (NLS) equation in multi-symplectic form. Preser-vation of the reduced energies shows that the reduced-order solutions ensure the long-term stability of the solutions.(c) 2022 Elsevier Inc. All rights reserved.Review Citation - WoS: 59Citation - Scopus: 78Web Application Testing: a Systematic Literature Review(Elsevier Science inc, 2014) Dogan, Serdar; Betin-Can, Aysu; Garousi, VahidContext: The web has had a significant impact on all aspects of our society. As our society relies more and more on the web, the dependability of web applications has become increasingly important. To make these applications more dependable, for the past decade researchers have proposed various techniques for testing web-based software applications. Our literature search for related studies retrieved 193 papers in the area of web application testing, which have appeared between 2000 and 2013. Objective: As this research area matures and the number of related papers increases, it is important to systematically identify, analyze, and classify the publications and provide an overview of the trends and empirical evidence in this specialized field. Methods: We systematically review the body of knowledge related to functional testing of web application through a systematic literature review (SLR) study. This SLR is a follow-up and complimentary study to a recent systematic mapping (SM) study that we conducted in this area. As part of this study, we pose three sets of research questions, define selection and exclusion criteria, and synthesize the empirical evidence in this area. Results: Our pool of studies includes a set of 95 papers (from the 193 retrieved papers) published in the area of web application testing between 2000 and 2013. The data extracted during our SLR study is available through a publicly-accessible online repository. Among our results are the followings: (1) the list of test tools in this area and their capabilities, (2) the types of test models and fault models proposed in this domain, (3) the way the empirical studies in this area have been designed and reported, and (4) the state of empirical evidence and industrial relevance. Conclusion: We discuss the emerging trends in web application testing, and discuss the implications for researchers and practitioners in this area. The results of our SLR can help researchers to obtain an overview of existing web application testing approaches, fault models, tools, metrics and empirical evidence, and subsequently identify areas in the field that require more attention from the research community. (C) 2014 Elsevier Inc. All rights reserved.
