3 results
Search Results
Now showing 1 - 3 of 3
Article Revolutionizing Glaucoma Care: Harnessing Artificial Intelligence for Precise Diagnosis and Management(2025) Ucgul, Ahmet Yucel; Aktas, ZeynepGlaucoma is a leading cause of irreversible blindness worldwide, necessitating early detection and effective management to prevent vision loss. Recent advancements in artificial intelligence (AI) have revolutionized glaucoma care by enhancing diagnostic accuracy, monitoring disease progression, and personalizing treatment strategies. AI models, including machine learning and deep learning algorithms, have demonstrated exceptional performance in analyzing fundus photography, optical coherence tomography, and visual field data, surpassing traditional diagnostic methods. Convolutional neural networks have shown high sensitivity and specificity in detecting glaucomatous changes, while vision transformers and hybrid AI models further refine risk assessment and prognosis. Additionally, AI- powered monitoring systems utilizing multi-modal data integration allow for more precise prediction of disease progression and the need for surgical intervention. The incorporation of AI into telemedicine and wearable intraocular pressure sensors extends glaucoma management to remote and underserved populations. Despite these advancements, challenges remain, including issues related to algorithm generalizability, data standardization, bias, and ethical concerns regarding AI-driven clinical decision-making. To maximize AI’s potential in glaucoma care, further interdisciplinary research, regulatory oversight, and multi-center validation studies are needed. By addressing these challenges, AI can be effectively integrated into clinical practice, leading to improved early detection, enhanced treatment strategies, and more personalized patient care. The future of AI in glaucoma management holds great promise, paving the way for a more data-driven and patient-centered approach to combating this sight-threatening disease.Article Citation - WoS: 1Citation - Scopus: 1Gonioscopy-Assisted Transluminal Trabeculotomy Versus Bent Ab Interno Needle Goniectomy in Patients With Open-Angle Glaucoma(Galenos Publ House, 2025) Ucgul, Ahmet Yucel; Ucgul, Rukiye Kilic; Aktas, ZeynepAmaç: Açık açılı glokomlu (AAG) hastalarda gonyoskopi yardımlı translüminal trabekülotomi (GATT) ile eğik iğne ab interno gonyektominin (BANG) etkinlik ve güvenliğini karşılaştırmak. Gereç ve Yöntem: Bu retrospektif karşılaştırmalı çalışma, GATT (34 göz) veya BANG (31 göz) uygulanan AAG tanılı 65 gözü içermektedir. Göz içi basınç (GİB), başlangıçta ve postoperatif takip vizitlerinde Goldmann applanasyon tonometresi ile ölçüldü. Cerrahi başarı, kısmi (GİB ≤21 mmHg ve ≥%20 azalma) ve tam (aynı kriterler ilaçsız) olarak kategorize edildi. Komplikasyonlar ve ek cerrahi gereksinimi not edildi. Bulgular: Ameliyat öncesi ortalama GİB, GATT grubunda 32,9±6,1 mmHg iken, BANG grubunda 31,8±5,4 mmHg idi. Son kontrolde, GATT grubunda ortalama GİB 15,8±4,5 mmHg’ye düşerken (%51,9 azalma), BANG grubunda 17,9±5,7 mmHg’ye (%43,7 azalma) düştü. Tam cerrahi başarı oranı GATT prosedürü için %88,2, BANG prosedürü için %61,3’tü. Erken cerrahi başarısızlıklar BANG grubunda daha sık görülürken, GATT grubunda erken başarısızlıklar daha nadir olsa da, geç dönemde cerrahi başarısızlıklar BANG grubuna göre daha sık izlendi. Her iki prosedürde de minimal komplikasyonlar görülmüş olup; en yaygın komplikasyon ise geçici hifemaydı. Sonuç: Bu çalışmada, GATT cerrahisinin, BANG cerrahisine kıyasla daha büyük ve daha sürdürülebilir GİB azalması sağladığı ve daha yüksek cerrahi başarı oranlarına sahip olduğu dikkate alındığında, AAG’nin yönetiminde GATT’ın daha güvenilir bir seçenek olduğu söylenebilir.Article Citation - Scopus: 1Outcomes of Gonioscopy-Assisted Transluminal Trabeculotomy in Children with Early-Onset Glaucoma Secondary To Sturge-Weber Syndrome(Elsevier, 2025) Aktas, Zeynep; El Sayed, Yasmine; Ucgul, Ahmet Yucel; Gawdat, Ghada; Elhilali, Hala; Aboalazayem, FayrouzPurpose: To evaluate the effectiveness and safety of gonioscopy-assisted transluminal trabeculotomy (GATT) in managing early-onset glaucoma secondary to Sturge-Weber syndrome (SWS). Design: A retrospective interventional case series. Participants: Medical records of 16 patients (22 eyes) diagnosed with early-onset glaucoma secondary to SWS who underwent GATT surgery were reviewed. Methods: All patients underwent GATT surgery using a 5-0 or 6-0 prolene suture under general anesthesia. Main Outcome Measures: The primary outcomes were intraocular pressure (IOP) reduction, complete surgical success (IOP <= 18 mmHg without medications), qualified surgical success (IOP <= 18 mmHg with medications), and postoperative complications. Results: The mean IOP decreased significantly from 25.4 +/- 4.8 mmHg at baseline to 15.7 +/- 4.2 mmHg at the final follow-up (P < 0.001), representing a 38.19% reduction. The mean age at the time of GATT surgery was 33.6 +/- 33.9 months. The mean follow-up duration was 16.3 +/- 6.4 months. Complete surgical success was achieved in 45.4% of eyes (10 out of 22), while qualified success was reached in 81.8% of eyes (18 out of 22). Despite the overall success, 18.1% of eyes (4 eyes) required additional surgical interventions during the follow-up period. These included Ahmed glaucoma valve implantation in 1 eye, trabeculectomy in 2 eyes, and transscleral diode laser cyclophotocoagulation in 1 eye. Transient hyphema was the only reported complication, resolving spontaneously within 1 week without further intervention. Conclusions: Gonioscopy-assisted transluminal trabeculotomy appears to be a promising surgical option for managing early-onset glaucoma in patients with SWS, offering significant IOP reduction and a favorable safety profile within the limitations of our study. However, further studies with longer follow-up periods and comparative groups are necessary to confirm these findings.
