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Article Citation - WoS: 2Citation - Scopus: 2Ultrafast Green Synthesis of Superparamagnetic Hybrid Nanoparticle for Advanced Applications(Wiley, 2025) Kibar, GunesThe integration of superparamagnetic iron oxide nanoparticles (SPIONs) into functional hybrid nanostructures remains a challenge, particularly in preserving their magnetic properties within composite frameworks. Herein, we present a rapid and environmentally friendly synthesis strategy for SPION-decorated polyhedral oligomeric silsesquioxane (POSS) nanoparticles. The process involves UV-induced polymerization to form POSS nanoparticles, followed by in situ SPION precipitation, with comprehensive characterization performed via SEM, FTIR, XRD, and VSM analyses. This approach enables the fabrication of hybrid nanoparticles (similar to 160 nm) within 5 min and subsequent SPION decoration in under an hour, ensuring (10 emu/g) superparamagnetic behavior. The developed method is highly scalable, efficient, and compatible with green chemistry principles, making it a promising platform for engineering advanced hybrid nanostructures. These nanoparticles hold significant potential for applications in biomedicine, catalysis, and next-generation material science.Article Citation - WoS: 5Citation - Scopus: 5Aptamer decorated PDA@magnetic silica microparticles for bacteria purification(Springer Wien, 2024) Kavruk, Murat; Babaie, Zahra; Kibar, Gunes; Cetin, Barbaros; Yesilkaya, Hasan; Amrani, Yassine; Ozalp, V. CengizOne significant constraint in the advancement of biosensors is the signal-to-noise ratio, which is adversely affected by the presence of interfering factors such as blood in the sample matrix. In the present investigation, a specific aptamer binding was chosen for its affinity, while exhibiting no binding affinity towards non-target bacterial cells. This selective binding property was leveraged to facilitate the production of magnetic microparticles decorated with aptamers. A novel assay was developed to effectively isolate S. pneumoniae from PBS or directly from blood samples using an aptamer with an affinity constant of 72.8 nM. The capture experiments demonstrated efficiencies up to 87% and 66% are achievable for isolating spiked S. pneumoniae in 1 mL PBS and blood samples, respectively.
