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Article Citation - WoS: 5Citation - Scopus: 9Deviations of Body Functions and Structure, Activity Limitations, and Participation Restrictions of the International Classification of Functioning, Disability, and Health Model in Children With Cystic Fibrosis and Non-Cystic Fibrosis Bronchiectasis(Wiley, 2020) Ozipek, Melike; Arikan, Hulya; Calik-Kutukcu, Ebru; Kerem-Gunel, Mintaze; Saglam, Melda; Inal-Ince, Deniz; Ozcelik, UgurBackground To the best of our knowledge, there is no study in the literature investigating the extrapulmonary outcomes of children with non-cystic fibrosis (CF) bronchiectasis and CF under the framework of the International Classification of Functioning, Disability, and Health (ICF) model. The purpose of the present study is to evaluate the children with CF and non-CF bronchiectasis using the ICF model. Materials and Methods Children with CF, non-CF bronchiectasis, and healthy counterparts were evaluated (20 participants in each group) according to the ICF items in domain b (body functions), domain s (body structures), and domain d (activities and participation). The pulmonary functions, respiratory and peripheral muscle strength tests, and posture analysis were carried out for domain b. For domain d, however, the Glittre-activities of daily living test and Pediatric Outcome Data Collection were used. Results Muscle strength of shoulder abductors and hip extensors in children with CF was significantly lower than healthy children and adolescents (P < .05). The severity of lateral and posterior postural abnormalities in children with CF and non-CF bronchiectasis was higher than those of healthy children (P < .05). Among the patient groups, global function, sports/physical function, expectations, transfers/basic mobility, and pain/comfort were the most affected participation dimensions (P < .05). Conclusions This study highlights the need for comprehensive up-to-date evaluation methods according to the ICF model for understanding rehabilitation requirements in CF and non-CF bronchiectasis in different age groups.Article Citation - WoS: 8Citation - Scopus: 8Physical fitness and activities of daily living in primary ciliary dyskinesia: A retrospective study(Wiley, 2022) Sonbahar-Ulu, Hazal; Cakmak, Aslihan; Inal-Ince, Deniz; Vardar-Yagli, Naciye; Yatar, Ilker; Calik-Kutukcu, Ebru; Ozcelik, UgurBackground Primary ciliary dyskinesia (PCD) is a rare, hereditary, autosomal recessive disorder characterized by recurrent upper and lower respiratory tract infections. This study aimed to compare pulmonary function, respiratory muscle strength, exercise capacity, physical fitness, and activities of daily living (ADLs) retrospectively between patients with PCD and healthy controls. Methods Data from 20 patients with PCD and 20 matched, healthy counterparts recorded between July 2015 and January 2017 were analyzed. The data evaluated and recorded included pulmonary function using a portable spirometer, respiratory muscle strength (using a mouth pressure device, exercise capacity using the incremental shuttle walk test,), physical fitness (using the Munich Fitness Test), and ADLs (using the Glittre ADL test). Results Pulmonary function, respiratory muscle strength, incremental shuttle walk test scores (all parameters), and total Munich Fitness Test scores were lower in the PCD group relative to controls (P < 0.05). The duration to complete the Glittre ADL test was higher in PCD patients than in healthy subjects (P < 0.05). Conclusions Pulmonary function, respiratory muscle strength, exercise capacity, physical fitness, and ADL were affected by PCD. Thus, pulmonary rehabilitation regimens should be tailored according to these impacts.Article Citation - WoS: 11Citation - Scopus: 11Visuomotor Reaction Time and Dynamic Balance in Children With Cystic Fibrosis and Non-Cystic Fibrosis Bronchiectasis: a Case-Control Study(Wiley, 2020) Dik, Jan; Saglam, Melda; Tekerlek, Haluk; Vardar-Yagli, Naciye; Calik-Kutukcu, Ebru; Inal-Ince, Deniz; Dogru, DenizObjective Extrapulmonary involvement such as balance and reaction time is unclear in cystic fibrosis (CF) patients. The aim of this study was to evaluate visuomotor reaction time (VMRT) and dynamic balance in children with CF and non-CF bronchiectasis compared to healthy children. Design/Methods Demographic and clinical characteristics were recorded. All children were evaluated with pulmonary function test (PFT) using a spirometer, incremental shuttle walk test (ISWT) for exercise capacity, Fitlight Trainer for VMRT, and functional reach test (FRT) for dynamic balance. Results Fourteen children with CF (10.71 +/- 2.94 years, 7 females), 17 children with non-CF bronchiectasis (12.75 +/- 2.81 years, 8 females), and 21 healthy children (11.36 +/- 3.28 years, 11 females) were included. Children with CF had longer total VMRT (P = .027), poorer FRT performance (P = .001), and shorter ISWT distances (P = .03) compared to the children with non-CF bronchiectasis and controls. Although total VMRT was longest in the CF group, there was no significant difference in mean VMRT among the CF, non-CF bronchiectasis, and control groups (P > .05). Conclusion Dynamic balance and VMRT show greater impairment in children with CF than in children with non-CF bronchiectasis compared to healthy controls. Our findings suggest that VMRT and dynamic balance should be taken into consideration for assessments and exercise programs in pulmonary rehabilitation.

