340 results
Search Results
Now showing 1 - 10 of 340
Article Citation - WoS: 2Citation - Scopus: 2Phase and Wave Dependent Analysis of Health Expenditure Efficiency: a Sample of Oecd Evidence(Frontiers Media Sa, 2023) Boduroglu, Elif; Atici, Kazim Baris; Omay, TolgaIntroductionHealth expenditures are a factor that reflects the government's public health policy and contributes to the protection of national health. Therefore, this study focuses on measuring the effectiveness of health expenditures in order to evaluate and improve the public health system and policy during the pandemic period. MethodIn order to examine the effectiveness of health expenditures, the behaviors of the pandemic process were analyzed in two stages. The number of daily cases is analyzed in the first stage by dividing it into waves and phases according to the transmission coefficient (R). For this classification, the discrete cumulative Fourier function estimation is used. In the second stage, the unit root test method was used to estimate the stationarity of the number of cases in order to examine whether the countries made effective health expenditures according to waves and phases. The series being stationary indicates that the cases are predictable and that health expenditure is efficient. Data consists of daily cases from February 2020 to November 2021 for 5 OECD countries. ConclusionThe general results are shown that cases cannot be predicted, especially in the first stage of the pandemic. In the relaxation phase and at the beginning of the second wave, the countries that were seriously affected by the epidemic started to control the number of cas es by taking adequate measures, thus increasing the efficiency of their health systems. The common feature of all the countries we examined is that phase 1, which represents the beginning of the waves, is not stationary. After the waves fade, it can be concluded that the stationary number of health cases cannot be sustainable in preventing new waves' formation. It is seen that countries cannot make effective health expenditures for each wave and stage. According to these findings, the periods in which countries made effective health expenditures during the pandemic are shown. DiscussionThe study aims to help countries make effective short- and long-term decisions about pandemics. The research provides a view of the effectiveness of health expenditures on the number of cases per day in 5 OECD countries during the COVID-19 Pandemic.Article Citation - WoS: 8Citation - Scopus: 9Propagation Measurements for Iqrf Network in an Urban Environment(Mdpi, 2022) Bouzidi, Mohammed; Dalveren, Yaser; Mohamed, Marshed; Dalveren, Yaser; Moldsvor, Arild; Cheikh, Faouzi Alaya; Derawi, Mohammad; Dalveren, Yaser; Department of Electrical & Electronics Engineering; Department of Electrical & Electronics EngineeringRecently, IQRF has emerged as a promising technology for the Internet of Things (IoT), owing to its ability to support short- and medium-range low-power communications. However, real world deployment of IQRF-based wireless sensor networks (WSNs) requires accurate path loss modelling to estimate network coverage and other performances. In the existing literature, extensive research on propagation modelling for IQRF network deployment in urban environments has not been provided yet. Therefore, this study proposes an empirical path loss model for the deployment of IQRF networks in a peer-to-peer configured system where the IQRF sensor nodes operate in the 868 MHz band. For this purpose, extensive measurement campaigns are conducted outdoor in an urban environment for Line-of-Sight (LoS) and Non-Line-of-Sight (NLoS) links. Furthermore, in order to evaluate the prediction accuracy of well-known empirical path loss models for urban environments, the measurements are compared with the predicted path loss values. The results show that the COST-231 Walfisch-Ikegami model has higher prediction accuracy and can be used for IQRF network planning in LoS links, while the COST-231 Hata model has better accuracy in NLoS links. On the other hand, the effects of antennas on the performance of IQRF transceivers (TRs) for LoS and NLoS links are also scrutinized. The use of IQRF TRs with a Straight-Line Dipole Antenna (SLDA) antenna is found to offer more stable results when compared to IQRF (TRs) with Meander Line Antenna (MLA) antenna. Therefore, it is believed that the findings presented in this article could offer useful insights for researchers interested in the development of IoT-based smart city applications.Article Citation - WoS: 76Citation - Scopus: 80Unique Ligand-Based Oxidative Dna Cleavage by Zinc(ii) Complexes of Hpyramol and Hpyrimol(Wiley-v C H verlag Gmbh, 2007) Maheswari, Palanisamy Uma; Barends, Sharief; Oezalp-Yaman, Seniz; de Hoog, Paul; Casellas, Helene; Teat, Simon J.; Reedijk, JanThe zinc(II) complexes reported here have been synthesised from the ligand 4-methyl-2-N-(2-pyridylmethyl)aminophenol (Hpyramol) with chloride or acetate counterions. All the five complexes have been structurally characterised, and the crystal structures reveal that the ligand Hpyramol gradually undergoes an oxidative dehydrogenation to form the ligand 4-methyl-2-N-(2-pyridylmethylene)aminophenol (Hpyrimol), upon coordination to Zn-II. All the five complexes cleave the phi X174 phage DNA oxidatively and the complexes with fully dehydrogenated pyrimol ligands were found to be more efficient than the complexes with non-dehydrogenated Hpyramol ligands. The DNA cleavage is suggested to be ligand-based, whereas the pure ligands alone do not cleave DNA. The DNA cleavage is strongly suggested to be oxidative, possibly due to the involvement of a non-diffusible phenoxyl radical mechanism. ne enzymatic religation experiments and DNA cleavage in the presence of different radical scavengers further support the oxidative DNA cleavage by the zinc(II) complexes.Article Fistulectomy and Primary Sphincteroplasty for Transsphincteric Fistula(Coll Physicians & Surgeons Pakistan, 2025) Emral, Ahmet Cihangir; Gulen, Merter; Ege, BahadirObjective: To evaluate the results of patients treated with fistulectomy and primary sphincteroplasty for uncomplicated perianal fistula. Study Design: Observational study. Place and Duration of the Study: Medicana International Hospital affiliated with Atilim University, Faculty of Medicine, Ankara, Turkiye, from January 2020 to September 2023. Methodology: In this study, patients who were operated on for perianal fistula between 2020 and 2023 were retrospectively examined. Data were obtained retrospectively. All patients underwent preoperative perianal MRI. Clinical notes were evaluated with the Cleveland Clinic Incontinence Score (CCIS) by physical examination. All patients were followed up on the first postoperative day, 1st week, 1st and 3rd postoperative months. Results: A total of 44 patients who underwent fistulectomy with primary sphincteroplasty were included in the study. Twenty-six patients (59.1%) had a history of perianal abscesses. It was observed that 34 (77.3%) of the patients had posterior, 7 (15.9%) anterior, and 3 (6.8%) lateral fistulas. A total of 3 patients (6.8%) were observed to have minor worsening in their incontinence scores. There was no statistically significant difference between the preoperative and postoperative 3rd month Cleveland Clinic Incontinence Score values of the patients (CCIS mean 1.6 vs. 1.7, respectively, p >0.05). Recurrence was observed in 1 patient (2.3%) during follow-ups. Conclusion: Fistulectomy with primary sphincteroplasty is an effective and reliable method to preserve anal continence and improve quality of life.Article Citation - WoS: 4Citation - Scopus: 7Real-Time Learning and Monitoring System in Fighting Against Sars-Cov in a Private Indoor Environment(Mdpi, 2022) Erisen, SerdarThe SARS-CoV-2 virus has posed formidable challenges that must be tackled through scientific and technological investigations on each environmental scale. This research aims to learn and report about the current state of user activities, in real-time, in a specially designed private indoor environment with sensors in infection transmission control of SARS-CoV-2. Thus, a real-time learning system that evolves and updates with each incoming piece of data from the environment is developed to predict user activities categorized for remote monitoring. Accordingly, various experiments are conducted in the private indoor space. Multiple sensors, with their inputs, are analyzed through the experiments. The experiment environment, installed with microgrids and Internet of Things (IoT) devices, has provided correlating data of various sensors from that special care context during the pandemic. The data is applied to classify user activities and develop a real-time learning and monitoring system to predict the IoT data. The microgrids were operated with the real-time learning system developed by comprehensive experiments on classification learning, regression learning, Error-Correcting Output Codes (ECOC), and deep learning models. With the help of machine learning experiments, data optimization, and the multilayered-tandem organization of the developed neural networks, the efficiency of this real-time monitoring system increases in learning the activity of users and predicting their actions, which are reported as feedback on the monitoring interfaces. The developed learning system predicts the real-time IoT data, accurately, in less than 5 milliseconds and generates big data that can be deployed for different usages in larger-scale facilities, networks, and e-health services.Article Citation - WoS: 3Citation - Scopus: 4A Simple Method To Set the Spray Properties for Flame Spray Pyrolysis Production of Nanoparticles(Elsevier Sci Ltd, 2020) Alhaleeb, Mustafi A.; Machin, Nesrin E.The most critical part of the flame spray pyrolysis (FSP) process is the nozzle, since it plays a key role in setting the spray properties. In this study, we developed an approach to adjust the nozzle throat gap size for a desired dispersion gas flow rate and upstream pressure, based on the external size and shape of a two phase external mixing nozzle. An equation was derived and validated by comparing the predicted gas flow rates with the data provided in a commercial nozzle supplier chart. Experiments were also conducted in our lab-scale FSP reactor to test the validity of the predictions. The approach developed here was found to closely predict the gap size necessary to pass the required dispersion gas flow at a desired pressure drop. Error in predictions was found to be less than 3% at an upstream pressure range of 3-10 bars. The isentropic flow assumption for perfect gases across the convergent-divergent nozzle was found to fail below 2 bars, consistent with the theory applied. By using the method here, the nozzle setting for a desired operation in an FSP process can be easily done, minimizing the time-consuming trial and error steps needed otherwise.Article Citation - WoS: 29Citation - Scopus: 33Risk Factors for Linezolid-Associated Thrombocytopenia and Negative Effect of Carbapenem Combination(J infection developing Countries, 2019) Kilic, Esra Kaya; Bulut, Cemal; Sonmezer, Meliha Cagla; Ozel, Ozlem; Hatipoglu, Cigdem Ataman; Ertem, Gunay Tuncer; Kinikli, SamiIntroduction: Linezolid is a synthetic antimicrobial agent with a broad spectrum of activity against virtually all Gram-positive bacteria. Although linezolid is generally well tolerated, the prolonged use of linezolid can lead to myelosuppression, including neutropenia, thrombocytopenia, and anemia. The aim of this study was investigating the risk factors for thrombocytopenia in patients who received linezolid therapy. Methodology: This retrospective study was performed on patients who received linezolid therapy between July 2007 and December 2017. Thrombocytopenia was defined as either a platelets count of < 100x10(9)/L or a 25% reduction from the baseline platelet count. Results: A total of 371 patients, (198 (53%) male and 173(47%) female were included into the study. Mean duration of therapy was 12.81 +/- 5.19 days. Linezolid-induced thrombocytopenia was detected in a total of 111 patients. Using the univariate analysis advanced sex, serum urea concentration, baseline platelet level and low eGFR value were found to be risk factors for linezolid associated thrombocytopenia (p < 0.05). According to a multivariate analysis, patients undergoing carbapenem treatment combination therapy (p = 0.003) and with a baseline platelet level of < 200x10(9)/L (p = 0.00) were found to have a high risk of developing thrombocytopenia. Conclusions: Several factors may influence of linezolid associated thrombocytopenia. Platelet count should be monitored during therapy and thrombocytopenia should be kept in mind in patients with baseline platelet level of < 200x10(9)/L, low eGFR, linezolid-carbapenem combination therapy.Article Citation - WoS: 2Citation - Scopus: 2Transcatheter valve-in-valve implantation Edwards Sapien XT in a direct flow valve after early degeneration(Wiley-hindawi, 2020) Duran Karaduman, Bilge; Ayhan, Huseyin; Bulguroglu, Serkan; Keles, Telat; Bozkurt, EnginIn recent years, the use of bioprosthetic valve (BPV) has increased significantly with both surgical aortic valve replacement (SAVR) and transcatheter aortic valve implantation (TAVI) due to reasons such as the advantage of not using anticoagulants. Nevertheless, major disadvantage of all BPV is the risk of early structural valve deterioration, leading to valve dysfunction, and requires reoperation, which significantly increases the risk of mortality or major morbidity especially after SAVR. There are a limited number of TAV-in-TAV case reports due to TAVI BPV degeneration. In our knowledge, this is the second report of TAV-in-TAV implantation wherein a previously implanted transfemoral 25-mm nonmetallic Direct Flow SVD valve treated with ViV TAVI via Edwards Sapien XT.Erratum Erratum: Correction to: Stem Cell and Advanced Nano Bioceramic Interactions (Advances in Experimental Medicine and Biology (2018) 1077 Doi: 10.1007/978-981-13-0947-2_17.)(2018) Köse, S.; Kankilic, B.; Gizer, M.; Ciftci Dede, E.; Bayramli, E.; Korkusuz, P.; Korkusuz, F.Article Citation - WoS: 9Citation - Scopus: 10Impact of Hospital-Acquired Acute Kidney Injury on Covid-19 Outcomes in Patients With and Without Chronic Kidney Disease: a Multicenter Retrospective Cohort Study(Tubitak Scientific & Technological Research Council Turkey, 2021) Ozturk, Savas; Turgutalp, Kenan; Arıcı, Mustafa; Çetinkaya, Hakkı; Altıparmak, Mehmet Rıza; Aydın, Zeki; Ateş, KenanBackground/aim: Hospital-acquired acute kidney injury (HA-AKI) may commonly develop in Covid-19 patients and is expected to have higher mortality. There is little comparative data investigating the effect of HA-AKI on mortality of chronic kidney disease (CKD) patients and a control group of general population suffering from Covid-19. Materials and methods: HA-AKI development was assessed in a group of stage 3–5 CKD patients and control group without CKD among adult patients hospitalized for Covid-19. The role of AKI development on the outcome (in-hospital mortality and admission to the intensive care unit [ICU]) of patients with and without CKD was compared. Results: Among 621 hospitalized patients (age 60 [IQR: 47–73]), women: 44.1%), AKI developed in 32.5% of the patients, as stage 1 in 84.2%, stage 2 in 8.4%, and stage 3 in 7.4%. AKI developed in 48.0 % of CKD patients, whereas it developed in 17.6% of patients without CKD. CKD patients with HA-AKI had the highest mortality rate of 41.1% compared to 14.3% of patients with HA-AKI but no CKD (p < 0.001). However, patients with AKI+non-CKD had similar rates of ICU admission, mechanical ventilation, and death rate to patients with CKD without AKI. Adjusted mortality risks of the AKI+non-CKD group (HR: 9.0, 95% CI: 1.9–44.2) and AKI+CKD group (HR: 7.9, 95% CI: 1.9–33.3) were significantly higher than that of the non-AKI+non-CKD group. Conclusion: AKI frequently develops in hospitalized patients due to Covid-19 and is associated with high mortality. HA-AKI has worse outcomes whether it develops in patients with or without CKD, but the worst outcome was seen in AKI+CKD patients.Key words: Acute kidney injury, chronic kidney disease, Covid-19, hospitalization, mortality
