Stimulus-Responsive Sequential Release Systems for Drug and Gene Delivery

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dc.authoridFatahi, Yousef/0000-0003-0374-2141
dc.authoridRabiee, Mohammad/0000-0003-1180-8729
dc.authoridRabiee, Navid/0000-0002-6945-8541
dc.authoridHamblin, Michael R/0000-0001-6431-4605
dc.authoridKarimi/0000-0002-7977-3940
dc.authoridahmadi, sepideh/0000-0002-6178-1168
dc.authoridNasseri, Behzad/0000-0003-3634-8327
dc.authorscopusid58189812000
dc.authorscopusid57201008317
dc.authorscopusid58070347200
dc.authorscopusid57217480243
dc.authorscopusid56560134100
dc.authorscopusid57205292283
dc.authorscopusid58948373100
dc.authorwosidHamblin, Mike/AAB-2511-2022
dc.authorwosidFatahi, Yousef/S-6193-2016
dc.authorwosidRabiee, Mohammad/L-9865-2018
dc.authorwosidRabiee, Navid/K-4407-2019
dc.authorwosidBagherzadeh, Mojtaba/AAE-6814-2020
dc.authorwosidBaheiraei, Nafiseh/P-4999-2019
dc.authorwosidKarimi/F-8405-2017
dc.contributor.authorAhmadi, Sepideh
dc.contributor.authorRabiee, Navid
dc.contributor.authorBagherzadeh, Mojtaba
dc.contributor.authorElmi, Faranak
dc.contributor.authorFatahi, Yousef
dc.contributor.authorFarjadian, Fatemeh
dc.contributor.authorHamblin, Michael R.
dc.date.accessioned2024-07-05T15:39:38Z
dc.date.available2024-07-05T15:39:38Z
dc.date.issued2020
dc.departmentAtılım Universityen_US
dc.department-temp[Ahmadi, Sepideh] Shahid Beheshti Univ Med Sci, Sch Adv Technol Med, Dept Med Cal Biotechnol, Student Res Comm, Tehran, Iran; [Ahmadi, Sepideh] Shahid Beheshti Univ Med Sci, Cellular & Mol Biol Res Ctr, Tehran, Iran; [Rabiee, Navid; Bagherzadeh, Mojtaba] Sharif Univ Technol, Dept Chem, Tehran, Iran; [Elmi, Faranak] Tabriz Univ Med Sci, Sch Adv Med Sci, Dept Biotechnol, Tabriz, Iran; [Elmi, Faranak] Islamic Azad Univ, Fac Sci, Dept Biol, Marand Branch, Marand, Iran; [Fatahi, Yousef] Univ Tehran Med Sci, Fac Pharm, Dept Pharmaceut Nanotechnol, Tehran, Iran; [Fatahi, Yousef] Univ Tehran Med Sci, Fac Pharm, Nanotechnol Res Ctr, Tehran, Iran; [Fatahi, Yousef] Universal Sci Educ & Res Ctr USERN, Tehran, Iran; [Farjadian, Fatemeh] Shiraz Univ Med Sci, Pharmaceut Sci Res Ctr, Sch Pharm, Shiraz, Iran; [Baheiraei, Nafiseh] Tarbiat Modares Univ, Fac Med Sci, Dept Hematol, Tissue Engn & Appl Cell Sci Div, Tehran, Iran; [Nasseri, Behzad] Hacettepe Univ, Bioengn Div, Chem Engn Dept, TR-06800 Ankara, Turkey; [Nasseri, Behzad] Hacettepe Univ, Bioengn Ctr, TR-06800 Ankara, Turkey; [Nasseri, Behzad] Atilim Univ, Chem Engn & Appl Chem Dept, TR-06830 Ankara, Turkey; [Rabiee, Mohammad] Amirkabir Univ Technol, Dept Biomed Engn, Biomat Grp, Tehran, Iran; [Dastjerd, Niloufar Tavakoli] Qazvin Univ Med Sci, Sch Allied Med Sci, Dept Med Biotechnol, Qazvin, Iran; [Valibeik, Ali] Lorestan Univ Med Sci, Sch Med, Dept Clin Biochem, Khorramabad, Iran; [Karimi, Mahdi] Iran Univ Med Sci, Cellular & Mol Res Ctr, Tehran, Iran; [Karimi, Mahdi] Iran Univ Med Sci, Fac Adv Technol Med, Dept Med Nanotechnol, Tehran, Iran; [Karimi, Mahdi] Iran Univ Med Sci, Oncopathol Res Ctr, Tehran, Iran; [Karimi, Mahdi] Univ Tehran Med Sci, Res Ctr Sci & Technol Med, Tehran, Iran; [Karimi, Mahdi] Islamic Azad Univ, Appl Biotechnol Res Ctr, Tehran Med Sci, Tehran, Iran; [Karimi, Mahdi; Hamblin, Michael R.] Harvard Med Sch, Wellman Ctr Photomed, Massachusetts Gen Hosp, Boston, MA 02114 USA; [Hamblin, Michael R.] Univ Johannesburg, Fac Hlth Sci, Laser Res Ctr, ZA-2028 Doornfontein, South Africaen_US
dc.descriptionFatahi, Yousef/0000-0003-0374-2141; Rabiee, Mohammad/0000-0003-1180-8729; Rabiee, Navid/0000-0002-6945-8541; Hamblin, Michael R/0000-0001-6431-4605; Karimi/0000-0002-7977-3940; ahmadi, sepideh/0000-0002-6178-1168; Nasseri, Behzad/0000-0003-3634-8327en_US
dc.description.abstractIn recent years, a range of studies have been conducted with the aim to design and characterize delivery systems that are able to release multiple therapeutic agents in controlled and programmed temporal sequences, or with spatial resolution inside the body. This sequential release occurs in response to different stimuli, including changes in pH, redox potential, enzyme activity, temperature gradients, light irradiation, and by applying external magnetic and electrical fields. Sequential release (SR)-based delivery systems, are often based on a range of different micro- or nanocarriers and may offer a silver bullet in the battle against various diseases, such as cancer. Their distinctive characteristic is the ability to release one or more drugs (or release drugs along with genes) in a controlled sequence at different times or at different sites. This approach can lengthen gene expression periods, reduce the side effects of drugs, enhance the efficacy of drugs, and induce an anti-proliferative effect on cancer cells due to the synergistic effects of genes and drugs. The key objective of this review is to summarize recent progress in SR-based drug/gene delivery systems for cancer and other diseases. (C) 2020 Elsevier Ltd. All rights reserved.en_US
dc.description.sponsorshipUS NIH [R01AI050875, R21AI121700]en_US
dc.description.sponsorshipMRH was supported by US NIH Grants R01AI050875 and R21AI121700.en_US
dc.identifier.citationcount123
dc.identifier.doi10.1016/j.nantod.2020.100914
dc.identifier.issn1748-0132
dc.identifier.issn1878-044X
dc.identifier.pmid32788923
dc.identifier.scopus2-s2.0-85087278714
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1016/j.nantod.2020.100914
dc.identifier.urihttps://hdl.handle.net/20.500.14411/3245
dc.identifier.volume34en_US
dc.identifier.wosWOS:000579498700005
dc.identifier.wosqualityQ1
dc.language.isoenen_US
dc.publisherElsevier Sci Ltden_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.scopus.citedbyCount155
dc.subjectSequential drug and gene releaseen_US
dc.subjectStimulus-responsive nanoparticlesen_US
dc.subjectCancer nanomedicineen_US
dc.subjectTemporal controlen_US
dc.subjectSynergistic combinationsen_US
dc.titleStimulus-Responsive Sequential Release Systems for Drug and Gene Deliveryen_US
dc.typeReviewen_US
dc.wos.citedbyCount146
dspace.entity.typePublication

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