Outcomes of Transcatheter Aortic Valve Implantation in Patients With and Without Diabetes Mellitus

dc.authorid Keles, Telat/0000-0001-5372-8351
dc.authorscopusid 26530826900
dc.authorscopusid 57189903577
dc.authorscopusid 6603167404
dc.authorscopusid 7003971982
dc.contributor.author Ayhan, Huseyin
dc.contributor.author Guney, Murat Can
dc.contributor.author Keles, Telat
dc.contributor.author Bozkurt, Engin
dc.date.accessioned 2024-09-10T21:34:11Z
dc.date.available 2024-09-10T21:34:11Z
dc.date.issued 2024
dc.department Atılım University en_US
dc.department-temp [Ayhan, Huseyin] Univ Hlth Sci, Sincan Educ & Res Hosp, Fac Med, Dept Cardiol, Ankara, Turkiye; [Guney, Murat Can] Atilim Univ, Medicana Int Ankara Hosp, Fac Med, Dept Cardiol, Ankara, Turkiye; [Keles, Telat] Ankara Yildirim Beyazit Univ, Ankara City Hosp, Fac Med, Dept Cardiol, Ankara, Turkiye; [Bozkurt, Engin] Medicana Int Ankara Hosp, Dept Cardiol, Ankara, Turkiye en_US
dc.description Keles, Telat/0000-0001-5372-8351 en_US
dc.description.abstract Introduction: Diabetes mellitus (DM) in patients undergoing cardiac transcatheter or surgical interventions usually is correlated with poor outcomes. Transcatheter aortic valve implantation (TAVI) has been developed as a therapy choice for inoperable, high-, or intermediate-risk surgical patients with severe aortic stenosis (AS). Objective: To evaluate the impact of DM and hemoglobin A1c (HbA1c) on outcomes and survival after TAVI. Methods: Five hundred and fifty-two symptomatic severe AS patients who underwent TAVI, of whom 164 (29.7%) had DM, were included in this retrospective study. Follow-up was performed after 30 days, six months, and annually. Results: The device success and risks of procedural-related complications were similar between patients with and without DM, except for acute kidney injury, which was more frequent in the DM group (2.4% vs. 0%, P=0.021). In-hospital and first-year mortality were similar between the groups (4.9% vs. 3.6%, P=0.490 and 15.0% vs. 11.2%, P=0.282, respectively). There was a statistical difference between HbA1c >= 6.5 and HbA1c <= 6.49 groups in total mortality (34.4% vs. 15.8%, P<0.001, respectively). The only independent predictors were Society of Thoracic Surgeons score (hazard ratio [HR] 1.28, 95% confidence interval [CI] 1.09-1.51; P=0.003) and HbA1c level >= 6.5 (HR 10.78, 95% CI 2.58-21.50; P=0.003) in multivariable logistic regression analysis. Conclusion: In this study, we conclude that DM was not correlated with an increased mortality risk or complication rates after TAVI. Also, it was shown that mortality was higher in patients with HbA1c >= 6.5, and it was an independent predictor for long-term mortality. en_US
dc.description.woscitationindex Science Citation Index Expanded
dc.identifier.citationcount 0
dc.identifier.doi 10.21470/1678-9741-2023-0088
dc.identifier.issn 0102-7638
dc.identifier.issn 1678-9741
dc.identifier.issue 4 en_US
dc.identifier.pmid 39038027
dc.identifier.scopus 2-s2.0-85199407999
dc.identifier.scopusquality Q3
dc.identifier.uri https://doi.org/10.21470/1678-9741-2023-0088
dc.identifier.uri https://hdl.handle.net/20.500.14411/7309
dc.identifier.volume 39 en_US
dc.identifier.wos WOS:001275157200001
dc.identifier.wosquality Q4
dc.institutionauthor Güney, Murat Can
dc.institutionauthor Ayhan, Hüseyin
dc.language.iso en en_US
dc.publisher Soc Brasil Cirurgia Cardiovasc en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.scopus.citedbyCount 1
dc.subject Transcatheter Aortic en_US
dc.subject Valve Replacement en_US
dc.subject Glycated Hemoglobin en_US
dc.subject Aortic Valve Stenosis en_US
dc.subject Diabetes Mellitus en_US
dc.subject Acute Kidney Injury en_US
dc.title Outcomes of Transcatheter Aortic Valve Implantation in Patients With and Without Diabetes Mellitus en_US
dc.type Article en_US
dc.wos.citedbyCount 1
dspace.entity.type Publication
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relation.isAuthorOfPublication.latestForDiscovery f9c4eb42-12de-4fc4-8ddb-670f7dcd0594

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