Aptamer Hybrid Nanocomplexes as Targeting Components for Antibiotic/Gene Delivery Systems and Diagnostics: a Review
| dc.contributor.author | Rabiee, Navid | |
| dc.contributor.author | Ahmadi, Sepideh | |
| dc.contributor.author | Arab, Zeynab | |
| dc.contributor.author | Bagherzadeh, Mojtaba | |
| dc.contributor.author | Safarkhani, Moein | |
| dc.contributor.author | Nasseri, Behzad | |
| dc.contributor.author | Tayebi, Lobat | |
| dc.date.accessioned | 2024-07-05T15:41:06Z | |
| dc.date.available | 2024-07-05T15:41:06Z | |
| dc.date.issued | 2020 | |
| dc.description | Safarkhani, Moein/0000-0001-7062-073X; Rabiee, Navid/0000-0002-6945-8541; Rabiee, Mohammad/0000-0003-1180-8729; ahmadi, sepideh/0000-0002-6178-1168; Nasseri, Behzad/0000-0003-3634-8327; Tayebi, Lobat/0000-0003-1947-5658 | en_US |
| dc.description.abstract | With the passage of time and more advanced societies, there is a greater emergence and incidence of disease and necessity for improved treatments. In this respect, nowadays, aptamers, with their better efficiency at diagnosing and treating diseases than antibodies, are at the center of attention. Here, in this review, we first investigate aptamer function in various fields (such as the detection and remedy of pathogens, modification of nanoparticles, antibiotic delivery and gene delivery). Then, we present aptamer-conjugated nanocomplexes as the main and efficient factor in gene delivery. Finally, we focus on the targeted co-delivery of genes and drugs by nanocomplexes, as a new exciting approach for cancer treatment in the decades ahead to meet our growing societal needs. | en_US |
| dc.identifier.doi | 10.2147/IJN.S248736 | |
| dc.identifier.issn | 1178-2013 | |
| dc.identifier.scopus | 2-s2.0-85087419841 | |
| dc.identifier.uri | https://doi.org/10.2147/IJN.S248736 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14411/3421 | |
| dc.language.iso | en | en_US |
| dc.publisher | Dove Medical Press Ltd | en_US |
| dc.relation.ispartof | International Journal of Nanomedicine | |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.subject | aptamer | en_US |
| dc.subject | polyethyleneimine | en_US |
| dc.subject | hybrid nanocomplexes | en_US |
| dc.subject | antibiotic | en_US |
| dc.subject | targeting | en_US |
| dc.subject | gene delivery systems | en_US |
| dc.title | Aptamer Hybrid Nanocomplexes as Targeting Components for Antibiotic/Gene Delivery Systems and Diagnostics: a Review | en_US |
| dc.type | Review | en_US |
| dspace.entity.type | Publication | |
| gdc.author.id | Safarkhani, Moein/0000-0001-7062-073X | |
| gdc.author.id | Rabiee, Navid/0000-0002-6945-8541 | |
| gdc.author.id | Rabiee, Mohammad/0000-0003-1180-8729 | |
| gdc.author.id | ahmadi, sepideh/0000-0002-6178-1168 | |
| gdc.author.id | Nasseri, Behzad/0000-0003-3634-8327 | |
| gdc.author.id | Tayebi, Lobat/0000-0003-1947-5658 | |
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| gdc.author.wosid | Bagherzadeh, Mojtaba/ABC-2351-2020 | |
| gdc.author.wosid | Safarkhani, Moein/AAU-1039-2021 | |
| gdc.author.wosid | Rabiee, Navid/K-4407-2019 | |
| gdc.author.wosid | Rabiee, Mohammad/L-9865-2018 | |
| gdc.author.wosid | ahmadi, sepideh/AAN-7491-2020 | |
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| gdc.description.department | Atılım University | en_US |
| gdc.description.departmenttemp | [Rabiee, Navid; Arab, Zeynab; Bagherzadeh, Mojtaba; Safarkhani, Moein] Sharif Univ Technol, Dept Chem, Tehran, Iran; [Ahmadi, Sepideh] Shahid Beheshti Univ Med Sci, Sch Adv Technol Med, Dept Med Biotechnol, Student Res Comm, Tehran, Iran; [Ahmadi, Sepideh] Shahid Beheshti Univ Med Sci, Cellular & Mol Biol Res Ctr, Tehran, Iran; [Nasseri, Behzad] Hacettepe Univ, Chem Engn Dept, TR-06800 Ankara, Turkey; [Nasseri, Behzad] Hacettepe Univ, Bioengn Div, TR-06800 Ankara, Turkey; [Nasseri, Behzad] Atilim Univ, Chem Engn & Appl Chem Dept, Ankara, Turkey; [Rabiee, Mohammad] Amirkabir Univ Technol, Dept Biomed Engn, Biomat Grp, Tehran, Iran; [Tahriri, Mohammadreza; Tayebi, Lobat] Marquette Univ, Sch Dent, Milwaukee, WI 53233 USA; [Webster, Thomas J.] Northeastern Univ, Dept Chem Engn, Boston, MA 02115 USA | en_US |
| gdc.description.endpage | 4256 | en_US |
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| gdc.description.startpage | 4237 | en_US |
| gdc.description.volume | 15 | en_US |
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| gdc.oaire.keywords | Gene Transfer Techniques | |
| gdc.oaire.keywords | aptamer | |
| gdc.oaire.keywords | Review | |
| gdc.oaire.keywords | Aptamers, Nucleotide | |
| gdc.oaire.keywords | Anti-Bacterial Agents | |
| gdc.oaire.keywords | hybrid nanocomplexes | |
| gdc.oaire.keywords | R5-920 | |
| gdc.oaire.keywords | Drug Delivery Systems | |
| gdc.oaire.keywords | International Journal of Nanomedicine | |
| gdc.oaire.keywords | Dentistry | |
| gdc.oaire.keywords | antibiotic | |
| gdc.oaire.keywords | Humans | |
| gdc.oaire.keywords | Nanoparticles | |
| gdc.oaire.keywords | Polyethyleneimine | |
| gdc.oaire.keywords | polyethyleneimine | |
| gdc.oaire.keywords | targeting | |
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