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Permanent URI for this collectionhttps://ada.atilim.edu.tr/handle/123456789/22

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Citation Count: 11
Vulnerability of groundwater to pollution from agricultural diffuse sources: a case study
(I W A Publishing, 2002) Muhammetoglu, H; Muhammetoglu, A; Soyupak, S
Kumluca, near Antalya in Turkey, is an important plain with its intensive agricultural activities employing greenhouses. The chemical fertilizer application practices caused excessive increases of the nitrogen, phosphorus and salinity within groundwater. A study has been initiated to assess the present state of the groundwater pollution problem of Kumluca Plain. A total of nine measurement and sampling stations have been selected to represent different depths groundwater table, different types of agricultural activities and different soil types. The magnitudes of the parameters: temperature, salinity and conductivity, nitrate, nitrite, ammonia, orthophosphate and fecal coliform were determined for groundwater. Soil samples collected from the stations have been analyzed for several parameters such as texture, total salinity, total nitrogen, and total phosphorus. The measurement and analyses results of the groundwater showed wide spatial variations depending on factors such as the quality of irrigation water, depth groundwater, soil characteristics, type and age of agriculture and hydrology. Groundwater vulnerabilities to pollution have been analyzed using the SEEPAGE Model approach. Furthermore the soil, aquifer and groundwater characteristics, which will be utilized to establish "cause" and "effect" relationships in future, have been clarified.
Citation Count: 12
Vulnerability of groundwater to pollution from agricultural diffuse sources: A case study
(IWA Publishing, 2002) Muhammetoǧlu,H.; Muhammetoǧlu,A.; Soyupak,S.
Kumluca, near Antalya in Turkey, is an important plain with its intensive agricultural activities employing greenhouses. The chemical fertilizer application practices caused excessive increases of the nitrogen, phosphorus and salinity within groundwater. A study has been initiated to assess the present state of the groundwater pollution problem of Kumluca Plain. A total of nine measurement and sampling stations have been selected to represent different depths groundwater table, different types of agricultural activities and different soil types. The magnitudes of the parameters: temperature, salinity and conductivity, nitrate, nitrite, ammonia, orthophosphate and fecal coliform were determined for groundwater. Soil samples collected from the stations have been analyzed for several parameters such as texture, total salinity, total nitrogen, and total phosphorus. The measurement and analyses results of the groundwater showed wide spatial variations depending on factors such as the quality of irrigation water, depth groundwater, soil characteristics, type and age of agriculture and hydrology. Groundwater vulnerabilities to pollution have been analyzed using the SEEPAGE Model approach. Furthermore the soil, aquifer and groundwater characteristics, which will be utilized to establish "cause" and "effect" relationships in future, have been clarified.
Citation Count: 6
Evaluation of efficiencies of diffuse allochthonous and autochthonous nutrient input control in restoration of a highly eutrophic lake
(I W A Publishing, 2002) Muhammetoglu, A; Muhammetoglu, H; Soyupak, S
Mogan Lake is an important recreational area for Metropolitan Ankara-Turkey. It is a shallow eutrophic lake with a dense growth of macrophytes. The main contributors of nutrients and other pollutants to the lake are the creeks carrying the runoff water from the watershed and upland farming land, in addition to the domestic and industrial wastewater discharges from a nearby town and industries. Hydrodynamic and water quality modeling techniques were used to determine the optimum management schemes for the lake restoration and diffuse pollution control. Management scenarios were devised and tested to control allochthonous and autochthonous nutrient inputs to the lake. Phosphorus and nitrogen load reductions were the main test elements for the control of allochthonous nutrient inputs. The scenario analysis revealed that reduction of phosphorus and nitrogen loads from diffused sources will have a marginal effect on controlling eutrophication if macrophyte growth is left uncontrolled. Scenarios employing macrophyte harvesting and sediment dredging have been evaluated for autochthonous nutrient input control. Sediment dredging alone has been shown to yield the most favorable conditions for water quality improvement in Mogan Lake. Further, control of diffuse pollution was an essential final step to achieve an acceptable long-term sustainable water quality improvement in the lake.
Citation Count: 102
A 1.6-mm, metal tube ultrasonic motor
(Ieee-inst Electrical Electronics Engineers inc, 2003) Cagatay, S; Koc, B; Uchino, K
A miniaturized metal tube ultrasonic motor, the dimensions of which are 1.6 mm in diameter and 6 rum in length, was developed. Two flattened surfaces with 90-degrees were ground on the outer surface of the stator. Two PZT-based piezoelectric ceramics were bonded onto these flat surfaces. The asymmetrical surface of the stator developed the split of the two degenerated orthogonal bending modes, resulting in a wobble motion. The working frequency of the 1.6-mm motor with 6 mm in length was 130 kHz. A torque of 0.5 mNm was reached at a maximum power of 45 mW with a speed of 45 rad/sec. The maximum efficiency was 16%.
Citation Count: 486
Stability analysis of social foraging swarms
(Ieee-inst Electrical Electronics Engineers inc, 2004) Gazi, V; Passino, KM
In this article we specify an M-member "individual-based" continuous time swarm model with individuals that move in an n-dimensional space according to an attractant/repellent or a nutrient profile. The motion of each individual is determined by three factors: i) attraction to the other individuals on long distances; ii) repulsion from the other individuals on short distances; and iii) attraction to the more favorable regions (or repulsion from the unfavorable regions) of the attractant/repellent profile. The emergent behavior of the swarm motion is the result of a balance between inter-individual interactions and the simultaneous interactions of the swarm members with their environment. We study the stability properties of the collective behavior of the swarm for different profiles and provide conditions for collective convergence to more favorable regions of the profile.
Citation Count: 196
A generalized LMI-Based approach to the global asymptotic stability of delayed cellular neural networks
(Ieee-inst Electrical Electronics Engineers inc, 2004) Singh, V; Department of Mechatronics Engineering
A novel linear matrix inequality (LMI)-based criterion for the global asymptotic stability and uniqueness of the equilibrium point of a class of delayed cellular neural networks (CNNs) is presented. The criterion turns out to be a generalization and improvement over some previous criteria.
Citation Count: 37
Synthesis, spectroscopy and electrochemical behaviors of nickel(II) complexes with tetradentate shiff bases derived from 3,5-Bu₂^t-salicylaldehyde
(Pergamon-elsevier Science Ltd, 2005) Kasumov, VT; Özalp-Yaman, S; Tas, E; Chemical Engineering
Nickel(II) complexes of a series of N,N'-polymethylenebis(3,5-Bu'(2)-salicylaidimine) ligands containing 2,4-di-Bu'(2)-phenol arms, NiLx, were synthesized and their spectroscopic and redox properties were examined. The UV-vis, H-1 NMR spectroscopic and magnetic results indicate that complexes NiL1-NiL4 unlike NiL5 and NiL6 have a square-planar structure in the solid state and in solution. Cyclic voltammograms of NiLx (x= 1-4) complexes displayed two-step oxidation processes. The first oxidation peak potentials of all Ni(II) complexes corresponds to the reversible one-electron oxidation process of the metal center, yielding Ni(III) species. The second oxidation peak of the complexes was assigned as the ligand based oxidation generating a coordinated phenoxyl radical species. (c) 2005 Elsevier B.V. All rights reserved.
Citation Count: 4
Assessment of nitrogen excess in an agricultural area using a nitrogen balance approach
(I W A Publishing, 2005) Muhammetoglu, H; Muhammetoglu, A; Soyupak, S
A pilot study has been initiated to develop an approach for quantification of nitrogen excesses from agricultural activities that involve greenhouse farming in Kumluca Plain, Turkey. Detailed calculations utilizing the nitrogen balance method (NBM) were carried out at nine different locations within the plain over a time period of one year. The major contributing factors and governing operative mechanisms taken into consideration were nitrogen application rates both as organic and chemical fertilizers, irrigation water to application practices, and nitrogen uptake by plants. The adopted approach yielded valuable information such as plant nitrogen uptake efficiencies, excess nitrogen, leaching rates and leachate nitrogen concentrations. Further, a site specific multiple linear regression model has been developed to estimate the ratio (N-leachate/N-groundwater) as a function of independent variables: farming age, excess nitrogen application and SEEPAGE Index Number. The negative sign of the model parameters implies that the ratio (N-leachate/N-groundwater) decreases as values of the independent variables increase. The adopted approach and the obtained results can beneficially be applied to similar sites to establish basic parameters of irrigation and fertilizer application operations.
Citation Count: 91
Effect of progesterone on DPPC membrane: Evidence for lateral phase separation and inverse action in lipid dynamics
(Elsevier Science inc, 2005) Korkmaz, F; Severcan, F; Physics Group
Interactions of progesterone with zwitterionic dipalmitoyl phosphatidylcholine (DPPC) triultilamellar liposomes were investigated as a function of temperature and progesterone concentration by using three non-invasive techniques namely Fourier transform infrared spectroscopy, turbidity at 440 nm, and differential scanning calorimetry. The results reveal that progesterone changes the physical properties of DPPC bilayers by decreasing the main phase-transition temperature, abolishing the pre-transition, broadening the phase-transition profile, disordering the system both in gel and liquid crystalline phase, increasing the dynamics at low concentrations whereas stabilizing the membrane at high concentrations, and inducing phase separation. Progesterone does not change the hydration of the C=O groups, while it strengthens the hydrogen bonding between the PO (2) over bar groups of lipids and the water molecules around. (c) 2005 Elsevier Inc. All rights reserved.
Citation Count: 7
Comparison of NAT1, NAT2 & GSTT2-2 activities in normal and neoplastic human breast tissues
(SAP - Slovak Academic Press, spol. s.r.o., 2006) Geylan-Su,Y.S.; Isgör,B.; Coban,T.; Kapucuoglu,N.; Aydintug,S.; Iscan,M.; Güray,T.
In this study, arylamine N-acetyltransferases, NATs (E.C.2.3.1.5) and glutathione-S-transferase-T2-2, GSTT2-2 (E.C.2.5.1.18) enzyme activities in the breast tumor and surrounding tumor-free tissues of 22 female breast cancer patients with infiltrating ductal carcinoma were measured. The possible impacts of grade of malignancy, chemotherapy treatment, estrogen receptor status and menopausal status on all enzyme activities were evaluated. The results showed that, both NAT2 and GSTT2-2 display significant differences between tumor and tumor-free breast tissues, while no difference was observed in NAT1. Grade of malignancy seems to be positively associated with NAT1 and negatively associated with GSTT2-2. Though, both NAT2 and GSTT2-2 have increased mean tumor activities, the grade of malignancy, chemotherapy status, menopausal status or estrogen receptor status are not correlated statistically.
Citation Count: 6
Comparison of NAT1, NAT2 & GSTT2-2 activities in normal and neoplastic human breast tissues
(Aepress Sro, 2006) Geylan-SU, YS; Isgör, B; Coban, T; Kapucuoglu, N; Aydintug, S; Iscan, M; Güray, T; Chemical Engineering
In this study, arylamine N-acetyltransferases, NATs (E.C.2.3.1.5) and glutathione-S-transferase-T2-2, GSTT2-2 (E.C.2.5.1.18) enzyme activities in the breast tumor and surrounding tumor-free tissues of 22 female breast cancer patients with infiltrating ductal carcinoma were measured. The possible impacts of grade of malignancy, chemotherapy treatment, estrogen receptor status and menopausal status on all enzyme activities were evaluated. The results showed that, both NAT2 and GSTT2-2 display significant differences between tumor and tumor-free breast tissues, while no difference was observed in NAT1. Grade of malignancy seems to be positively associated with NAT1 and negatively associated with GSTT2-2. Though, both NAT2 and GSTT2-2 have increased mean tumor activities, the grade of malignancy, chemotherapy status, menopausal status or estrogen receptor status are not correlated statistically.
Citation Count: 3
Our experience in cardiac transplantation in Baskent University
(Elsevier Science inc, 2006) Sezgin, A; Gültekin, B; Özkan, S; Akay, T; Uguz, E; Tokalak, I; Aslamaci, S; Department of Social Sciences for University wide Courses
Recently cardiac transplantation has an important place in treatment of end-stage cardiac failure. In Turkey between 2003 and 2005 at 10 centers 64 cardiac transplantations were performed including five at our facility. Herein we have presented our results. All patients were men of mean age 34.2 +/- 10.7 (17 to 44) years. Upon preoperative echocardiography their mean ejection fraction was 18% +/- 3.27% (17% to 23%). Pulmonary vascular resistance was 4.47 wood unit in one patient and in one case, there was Rh incompatibility between donor and recipient. We used HTK solution for protection of donor hearts. Mean ischemia time was 251.2 +/- 62.7 minutes (155 to 314). Mean aortic clamping time was 84 +/- 4.7 minutes (80 to 90). In all patients we performed a biatrial anastomosis technique. Hemofiltration was used to prevent hemodilution during operation. In the postoperative period four patients had acute renal dysfunction; one, a minor cerebrovascular accident; two, reoperated because of bleeding; one, cholestasis; one, temporary atrio-ventricular block; and one, mediastinitis. Mean follow-up time was 15.6 +/- 19.7 months (2 to 50). Neither early nor late mortality has occurred. All patients are in New York Heart Association class I. In all cases we used triple immunosuppressive therapy. In the follow-up period the mean number of cardiac biopsies per patient was 4.2 +/- 3.03 (2 to 8). Two cases had cardiac catheterization. As a complication of cardiac biopsy, pericardial tamponade developed in one patient; in another one we observed a right ventricular aneursym after cardiac biopsy. Cardiac transplantation was performed with low mortality and morbidity rates in end-stage cardiac failure patients with longer life expectancy and higher life quality. Unfortunately in our country, because of difficulties to find donor hearts, cardiac transplantations were small in number. For better results, we need a larger series.
Citation Count: 62
Pedestrian self-reports of factors influencing the use of pedestrian bridges
(Pergamon-elsevier Science Ltd, 2007) Rasanen, Mikko; Lajunen, Timo; Alticafarbay, Farahnaz; Aydin, Cumhur; Department of Civil Engineering
The study was designed to find out factors that influence use/non-use of pedestrian bridges. The use rate of five pedestrian bridges was observed in the central business district (CBD) of Ankara. After the observations, a survey was conducted among pedestrians using those bridges and crossing contrary to safe practice under them at street level (n = 408). In the present data, the use rate of pedestrian bridges varied from 6 to 63%. The frequent use of the bridge when crossing the road concerned, and seeing bridge use as time saving and safe in general were positively related to respondents' bridge use. Frequent visits to CBD decreased the likelihood of using the bridge. Other factors accounted only for a small proportion of variance in bridge use. The study suggests that bridge use or non-use is a habit and not coincidental behaviour. For increasing the pedestrians' bridge use, escalators seem to be a good solution, but traffic signals under a bridge may deteriorate the use rate. In addition, increasing the number of legs leading to the bridge may not increase the use rate. The use rate is likely to improve, if the safety benefits and convenience of using the bridge without considerable time loss are clearly visible to pedestrians. (c) 2007 Elsevier Ltd. All rights reserved.
Citation Count: 71
Unique ligand-based oxidative DNA cleavage by zinc(II) complexes of hpyramol and hpyrimol
(Wiley-v C H verlag Gmbh, 2007) Maheswari, Palanisamy Uma; Barends, Sharief; Oezalp-Yaman, Seniz; de Hoog, Paul; Casellas, Helene; Teat, Simon J.; Reedijk, Jan; Chemical Engineering
The zinc(II) complexes reported here have been synthesised from the ligand 4-methyl-2-N-(2-pyridylmethyl)aminophenol (Hpyramol) with chloride or acetate counterions. All the five complexes have been structurally characterised, and the crystal structures reveal that the ligand Hpyramol gradually undergoes an oxidative dehydrogenation to form the ligand 4-methyl-2-N-(2-pyridylmethylene)aminophenol (Hpyrimol), upon coordination to Zn-II. All the five complexes cleave the phi X174 phage DNA oxidatively and the complexes with fully dehydrogenated pyrimol ligands were found to be more efficient than the complexes with non-dehydrogenated Hpyramol ligands. The DNA cleavage is suggested to be ligand-based, whereas the pure ligands alone do not cleave DNA. The DNA cleavage is strongly suggested to be oxidative, possibly due to the involvement of a non-diffusible phenoxyl radical mechanism. ne enzymatic religation experiments and DNA cleavage in the presence of different radical scavengers further support the oxidative DNA cleavage by the zinc(II) complexes.
Citation Count: 31
Comparison between alternating aerobic-anoxic and conventional activated sludge systems
(Pergamon-elsevier Science Ltd, 2007) Balku, Saziye; Energy Systems Engineering
Conventional activated sludge systems ensure removal of colloidal and dissolved carbonaceous organic matter whereas alternating aerobic-anoxic systems, in addition, satisfy a further reduction in nitrogen content of wastewater. Main difference between them is that the alternating system should also include an anoxic operation mode which satisfies denitrification. In other words conventional systems are operated under aerobic conditions whereas alternating systems require a periodical change from aerobic conditions to anoxic conditions. So the most important problem in alternating systems is to find the appropriate durations for both sequences. In this study a comparison between conventional and alternating systems is considered in terms of nitrogen removal and aeration time by simulation under the same conditions together with an optimization algorithm. The results show that an activated sludge system can be operated as an alternating aerobic-anoxic system so that nitrogen removal is also possible during treatment without any additional investment or operational cost. (C) 2007 Elsevier Ltd. All rights reserved.
Citation Count: 43
Platinated copper(3-clip-phen) complexes as effective DNA-cleaving and cytotoxic agents
(Wiley-v C H verlag Gmbh, 2008) Ozalp-Yaman, Seniz; de Hoog, Paul; Amadei, Giulio; Pitie, Marguerite; Gamez, Patrick; Dewelle, Janique; Reedijk, Jan; Chemical Engineering
The synthesis and biological activity of three heteronuclear platinum-copper complexes based on 3-Clip-Phen are reported. These rigid complexes have been designed to alter the intrinsic mechanism of action of both the platinum moiety and the Cu(3-Clip-Phen) unit. The platinum centers of two of these complexes are coordinated to a 3-Clip-Phen moiety, an ammine ligand and two chlorides, which are either cis or trans to each other. The third complex comprises two 3-Clip-Phen units and two chloride ligands bound in a trans fashion to the platinum ion. DNA-cleavage experiments show that the complexes are highly efficient nuclease agents. In addition, a markedly difference in their aptitude to perform direct double-strand cleavage is observed, which appears to be strongly related to the ability of the platinum unit to coordinate to DNA. Indeed, complex 6 is unable to coordinate to DNA, which is reflected by its incapability to carry out double-strand breaks. Nonetheless, this complex exhibits efficient DNA-cleavage activity, and its cytotoxicity is high for several cell lines. Complex 6 shows better antiproliferate activity than both cisplatin and Cu(3-Clip-Phen) toward most cancer cell lines. Furthermore, the cytotoxicity observed for 1 is for most cell lines close to that of cisplatin, or even better. Cu(3-Clip-Phen) induces very low cytotoxic effects, but a marked migratory activity. Complex 6 presents DNA-cleavage properties comparable to the one of Cu(3-Clip-Phen), but it does not show any migratory activity. Interestingly, both Cu(3-Clip-Phen) and 6 induces vacuolisation processes in the cell in contrast to complex 1 and cisplatin. Thus, the four complexes cisplatin tested, Cu(3-Clip-Phen), I and 6 stimulate different cellular responses.
Citation Count: 27
Comparison of cellular proliferation on dense and porous PCL scaffolds
(Ios Press, 2008) Sasmazel, Hilal Tuerkoglu; Gumusderelioglu, Menemse; Gurpinar, Aylin; Onur, Mehmet Ali; Metallurgical and Materials Engineering
In this contribution, PCL (poly-e caprolactone) scaffolds were prepared by solvent-casting/particle-leaching technique in the presence of two pore formers, PEG(4000) or sucrose molecules in different quantities (0, 10, 20, 30, 40, 50, 55 w/w% PEG(4000)/PCL; 10, 20 w/w% Sucrose/ PCL). The surface and bulk properties of the resulting scaffolds were studied by SEM, DSC and FTIR. SEM photographs showed that, macroporosity was obtained in the PCL structures prepared with sucrose crystals while microporous structure was obtained in the presence of PEG(4000) molecules. Average pore diameters calculated from SEM photographs were 40.1 and 191.2 mu m for 40% PEG(4000)/PCL and 10% Sucrose/PCL scaffolds, respectively. The DSC and FTIR results confirmed that there is no any interaction between pore formers and PCL during structural formation, and both pore formers, PEG(4000) and sucrose, remained independently in the scaffolds. L929 mouse fibroblast cells were seeded onto PCL structures and maintained during 7 days to evaluate cell proliferation. Cell culture results showed that, 10% Sucrose/ PCL scaffold was the most promising substrate for L929 cell growth due to 3-D architecture and macroporous structure of the scaffold.
Citation Count: 30
Comparison of biomechanical behaviour of maxilla following Le Fort I osteotomy with 2-versus 4-plate fixation using 3D-FEA. Part 1: Advancement surgery
(Churchill Livingstone, 2008) Atac, M. S.; Erkmen, E.; Yucel, E.; Kurt, A.
The study aimed to calculate the location and intensity of the maximum stress fields on the fixation plates and surrounding maxilla following Le Fort I osteotomies after advancement procedures using three-dimensional finite element analysis. The models were generated using skull CT scan data. Le Fort I osteotomy Simulations were made and two separate impacted maxillary models were designed. The ADV-2 model has 2 plate fixations bilaterally at the piriform rims, the ADV-4 model has 4 plate fixations at the zygomatic buttresses and piriform rims. The stress fields on bone, plate and screws were computed for each model. Posterior occlusal loads were simulated on one side in the molar-premolar region, in all three directions, reflecting the chewing forces. The increased locations of highest Von Mises stresses on the plates and highest maximum principle stresses on the bones were determined in ADV-2 models especially Under horizontal and oblique loads when compared with ADV-4 models. Evaluation of the highest Von Mises Stress Values and maximum principal stress revealed that oblique load in the ADV-2 model received the highest values. 4-plate fixation following Le Fort I advancement Surgery exerts less stress on the maxillary bones and fixation materials than 2-plate fixation.
Citation Count: 6
Analysis of the Hall effect in TlGaTe₂ single crystals
(Iop Publishing Ltd, 2009) Qasrawi, A. F.; Gasanly, N. M.; Department of Electrical & Electronics Engineering
The electrical resistivity and Hall coefficient of p-type TlGaTe2 crystals were measured in the temperature range of 110-320 K. The electrical resistivity, charge carrier density and Hall mobility data for the crystals have been analyzed by means of existing theories and models to determine the extrinsic energy levels, the carrier effective mass, the donor and acceptor concentrations and the dominant scattering mechanism in the crystal as well. The analysis of the temperature-dependent electrical resistivity recorded parallel and perpendicular to the crystal's axis ( c-axis) reflected the existence of energy levels located at 0.26 and at 0.20 eV, respectively. The difference of these two energy levels is due to crystal anisotropy. The energy level at 0.26 eV was found to represent an acceptor level, as confirmed from Hall data analysis. The temperature dependence of the carrier density was analyzed by using the single-donor-single-acceptor model. The latter analysis revealed the carrier effective mass and the acceptor and donor concentrations as 0.73m(0), 4.10 x 10(17) cm(-3) and 1.20 x 10(17) cm(-3), respectively. The Hall mobility of TlGaTe2 is found to be limited by the scattering of hole-acoustic phonon interactions. The calculated theoretical mobility fits to the experimental one under the condition that the acoustic deformation potential is 11.0 eV, which is the energy position of the top of valence band maximum that is formed by the Te 5s states.
Citation Count: 16
A glow in the dark: synthesis and electropolymerization of a novel chemiluminescent terthienyl system
(Royal Soc Chemistry, 2009) Asil, Demet; Cihaner, Atilla; Onal, Ahmet M.; Chemical Engineering
The synthesis and characterization of a unique (electro)-chemiluminescent monomer based on a terthienyl system, and its corresponding polymer which is the first example of an electro-active chemiluminescent polymer bearing a pyridazine appendage, are described.

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