Dietary Total Antioxidant Capacity and Oxidative Stress in Patients With Type-2 Diabetes

dc.authorid CETINER, OZLEM/0000-0001-9872-416X
dc.authorid Yalçın, Tuba/0000-0002-4820-8180
dc.authorid Rakicioglu, Neslisah/0000-0001-8763-7407
dc.authorscopusid 57222153256
dc.authorscopusid 55536356400
dc.authorscopusid 57192717388
dc.authorscopusid 7003524225
dc.authorscopusid 12798033700
dc.authorwosid Sendur, Suleyman N/R-2450-2018
dc.authorwosid Cetiner, Ozlem/AAZ-6733-2021
dc.authorwosid CETINER, OZLEM/GRF-4333-2022
dc.authorwosid Yalçın, Tuba/ABR-2906-2022
dc.contributor.author Cetiner, Ozlem
dc.contributor.author Sendur, Suleyman Nahit
dc.contributor.author Yalcin, Tuba
dc.contributor.author Bayraktar, Miyase
dc.contributor.author Rakicioglu, Neslisah
dc.contributor.other Nutrition and Dietetics
dc.date.accessioned 2024-07-05T15:19:31Z
dc.date.available 2024-07-05T15:19:31Z
dc.date.issued 2021
dc.department Atılım University en_US
dc.department-temp [Cetiner, Ozlem] Atilim Univ, Dept Nutr & Dietet, Ankara, Turkey; [Sendur, Suleyman Nahit; Bayraktar, Miyase] Hacettepe Univ, Fac Med, Dept Internal Dis, Endocrinol Subdiv, Ankara, Turkey; [Yalcin, Tuba; Rakicioglu, Neslisah] Hacettepe Univ, Dept Nutr & Dietet, TR-06100 Ankara, Turkey en_US
dc.description CETINER, OZLEM/0000-0001-9872-416X; Yalçın, Tuba/0000-0002-4820-8180; Rakicioglu, Neslisah/0000-0001-8763-7407 en_US
dc.description.abstract Background: Reactive oxygen species can disrupt normal cellular functions by damaging DNA, protein, and lipid structures of the cell. Some antioxidant molecules may protect the body against reactive oxygen species. We aimed to investigate the relationship between the dietary intake of antioxidants and oxidative DNA damage in diabetic patients. Material and Methods: A total of 85 individuals were included in the study, of which 30 were newly diagnosed with type-2 diabetes, 30 were formerly diagnosed with type-2 diabetes, and 25 were healthy individuals. Twenty-four-hour dietary recalls were recorded for 3 consecutive days. Dietary total antioxidant capacity and dietary oxidative balance scores were calculated according to these records. Spot urine samples were collected and analyzed for 8-hydroxy-2' deoxyguanosine/creatinine. Results: Dietary total antioxidant capacity, estimated via different methods, was higher in the controls than that in patients with type-2 diabetes (p<0.05). The urinary 8-hydroxy-2'-deoxyguanosine/creatinine ratio, a reliable predictor of oxidative DNA damage, was also higher in non-diabetic patients (p<0.05). The urinary 8-hydroxy-2'-deoxyguanosine/creatinine ratio was not related to dietary antioxidant intake (p>0.05). Conclusion: Urinary 8-hydroxy-2'-deoxyguanosine/creatinine concentration may not always reflect the current oxidative status of the body. en_US
dc.identifier.citationcount 0
dc.identifier.doi 10.23751/pn.v23i2.9695
dc.identifier.issn 1129-8723
dc.identifier.issue 2 en_US
dc.identifier.scopus 2-s2.0-85109455156
dc.identifier.scopusquality Q3
dc.identifier.uri https://doi.org/10.23751/pn.v23i2.9695
dc.identifier.uri https://hdl.handle.net/20.500.14411/1976
dc.identifier.volume 23 en_US
dc.identifier.wos WOS:000669548500014
dc.institutionauthor Çetiner, Özlem
dc.language.iso en en_US
dc.publisher Mattioli 1885 en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.scopus.citedbyCount 1
dc.subject Antioxidants en_US
dc.subject diet en_US
dc.subject DNA damage en_US
dc.subject type 2 diabetes en_US
dc.subject oxidative stress en_US
dc.title Dietary Total Antioxidant Capacity and Oxidative Stress in Patients With Type-2 Diabetes en_US
dc.type Article en_US
dc.wos.citedbyCount 1
dspace.entity.type Publication
relation.isAuthorOfPublication 1f2dc58a-135d-4b90-88f2-22765dd32a3c
relation.isAuthorOfPublication.latestForDiscovery 1f2dc58a-135d-4b90-88f2-22765dd32a3c
relation.isOrgUnitOfPublication 2071c428-f13d-4e73-b6f2-9902e8f00103
relation.isOrgUnitOfPublication.latestForDiscovery 2071c428-f13d-4e73-b6f2-9902e8f00103

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