Özkan, Ozan

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Profile URL
https://hdl.handle.net/20.500.14411/7175
Name Variants
O., Özkan
O.,Ozan
Ozkan,O.
Ozan, Ozkan
Özkan,O.
O.,Özkan
Ozkan, Ozan
Özkan, Ozan
Ö.,Ozan
O., Ozkan
Ozan, Özkan
O., Ozan
Ö., Ozan
O.,Ozkan
Job Title
Doktor Öğretim Üyesi
Email Address
ozan.ozkan@atilim.edu.tr
Main Affiliation
Metallurgical and Materials Engineering
Status
Website
ORCID ID
Scopus Author ID
57189848353
Turkish CoHE Profile ID
Google Scholar ID
WoS Researcher ID
IUF-1471-2023

Sustainable Development Goals

NO POVERTY1
NO POVERTY
0
Research Products
ZERO HUNGER2
ZERO HUNGER
0
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GOOD HEALTH AND WELL-BEING3
GOOD HEALTH AND WELL-BEING
2
Research Products
QUALITY EDUCATION4
QUALITY EDUCATION
0
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GENDER EQUALITY5
GENDER EQUALITY
0
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CLEAN WATER AND SANITATION6
CLEAN WATER AND SANITATION
0
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AFFORDABLE AND CLEAN ENERGY7
AFFORDABLE AND CLEAN ENERGY
0
Research Products
DECENT WORK AND ECONOMIC GROWTH8
DECENT WORK AND ECONOMIC GROWTH
0
Research Products
INDUSTRY, INNOVATION AND INFRASTRUCTURE9
INDUSTRY, INNOVATION AND INFRASTRUCTURE
0
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REDUCED INEQUALITIES10
REDUCED INEQUALITIES
0
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SUSTAINABLE CITIES AND COMMUNITIES11
SUSTAINABLE CITIES AND COMMUNITIES
0
Research Products
RESPONSIBLE CONSUMPTION AND PRODUCTION12
RESPONSIBLE CONSUMPTION AND PRODUCTION
0
Research Products
CLIMATE ACTION13
CLIMATE ACTION
0
Research Products
LIFE BELOW WATER14
LIFE BELOW WATER
0
Research Products
LIFE ON LAND15
LIFE ON LAND
0
Research Products
PEACE, JUSTICE AND STRONG INSTITUTIONS16
PEACE, JUSTICE AND STRONG INSTITUTIONS
0
Research Products
PARTNERSHIPS FOR THE GOALS17
PARTNERSHIPS FOR THE GOALS
0
Research Products
Documents

6

Citations

125

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Documents

8

Citations

138

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Scholarly Output

7

Articles

7

Views / Downloads

31/0

Supervised MSc Theses

0

Supervised PhD Theses

0

WoS Citation Count

114

Scopus Citation Count

97

Patents

0

Projects

0

WoS Citations per Publication

16.29

Scopus Citations per Publication

13.86

Open Access Source

1

Supervised Theses

0

JournalCount
Journal of Nanoscience and Nanotechnology2
International Journal of Pharmaceutics1
International Journal of Polymeric Materials and Polymeric Biomaterials1
Journal of Biomaterials Applications1
Journal of Bioscience and Bioengineering1
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Author: Turkoglu Sasmazel, Hilal

Scholarly Output Search Results

Now showing 1 - 4 of 4
  • Thumbnail Image
    Article
    Citation - WoS: 18
    Citation - Scopus: 19
    Effects of Nozzle Type Atmospheric Dry Air Plasma on L929 Fibroblast Cells Hybrid Poly (ε-caprolactone)/Chitosan (ε-Caprolactone) Scaffolds Interactions
    (Soc Bioscience Bioengineering Japan, 2016) Ozkan, Ozan; Sasmazel, Hilal Turkoglu; Turkoglu Sasmazel, Hilal
    In the study presented here, in order to improve the surface functionality and topography of poly (epsilon-caprolactone) (PCL)/chitosan/PCL hybrid tissue scaffolds fabricated layer by layer with electrospinning technique, an atmospheric pressure nozzle type plasma surface modification was utilized. The optimization of the plasma process parameters was carried out by monitoring the changes in surface hydrophilicity by using contact angle measurements. SEM, AFM and XPS analyses were utilized to observe the changes in topographical and chemical properties of the modified surfaces. The results showed that applied plasma modification altered the nanotopography and the functionality of the surfaces of the scaffolds. The modification applied for 9 min from a distance of 17 cm was found to provide the possible contact angle value (75.163 +/- 0.083) closest to the target value which is the value of tissue culture polystyrene (TCPS) petri dishes (similar to 49.7 degrees), compared to the unmodified samples (84.46 +/- 3.86). In vitro cell culture was carried out by L929 mouse fibroblast cell line in order to examine the effects of plasma surface modification on cell material interactions. Standard MIT assay showed improved cell viability on/within modified scaffolds confirmed with the observations of the cell attachment and the morphology by means of SEM, fluorescence and confocal imaging. The experiments performed in the study proved the enhanced biocompatibility of the nozzle type dry air plasma modified scaffolds. (C) 2016, The Society for Biotechnology, Japan. All rights reserved.
  • Thumbnail Image
    Article
    Citation - WoS: 39
    Citation - Scopus: 44
    A Novel Treatment Strategy for Preterm Birth: Intra-Vaginal Progesterone-Loaded Fibrous Patches
    (Elsevier, 2020) Cam, Muhammet Emin; Hazar-Yavuz, Ayse Nur; Cesur, Sumeyye; Ozkan, Ozan; Alenezi, Hussain; Sasmazel, Hilal Turkoglu; Edirisinghe, Mohan; Turkoglu Sasmazel, Hilal
    Progesterone-loaded poly(lactic) acid fibrous polymeric patches were produced using electrospinning and pressurized gyration for infra-vaginal application to prevent preterm birth. The patches were intravaginally inserted into rats in the final week of their pregnancy, equivalent to the third trimester of human pregnancy. Maintenance tocolysis with progesterone-loaded patches was elucidated by recording the contractile response of uterine smooth muscle to noradrenaline in pregnant rats. Both progesterone-loaded patches indicated similar results from release and thermal studies, however, patches obtained by electrospinning had smaller average diameters and more uniform dispersion compared to pressurized gyration. Patches obtained by pressurized gyration had better results in production yield and tensile strength than electrospinning; thereby pressurized gyration is better suited for scaled-up production. The patches did not affect cell attachment, viability, and proliferation on Vero cells negatively. Consequently, progesterone-loaded patches are a novel and successful treatment strategy for preventing preterm birth.
  • Thumbnail Image
    Article
    Citation - WoS: 9
    Citation - Scopus: 9
    Dielectric Barrier Discharge and Jet Type Plasma Surface Modifications of Hybrid Polymeric Poly (ε-caprolactone)/Chitosan Scaffolds
    (Sage Publications Ltd, 2018) Ozkan, Ozan; Sasmazel, Hilal Turkoglu; Turkoglu Sasmazel, Hilal
    In this study, dry air plasma jet and dielectric barrier discharge Ar+O-2 or Ar+N-2 plasma modifications and their effects on wettability, topography, functionality and biological efficiency of the hybrid polymeric poly (epsilon-caprolactone)/chitosan scaffolds were reported. The samples treated with Ar+O-2 dielectric barrier discharge plasma (80 sccm O-2 flow rate, 3-min treatment) or with dry air plasma jet (15-cm nozzle-sample distance, 13-min treatment) had the closest wettability (49.11 +/- 1.83 and 53.60 +/- 0.95, respectively) to the commercial tissue culture polystyrene used for cell cultivation. Scanning electron microscopy images and X-ray photoelectron spectrometry analysis showed increase in topographical roughness and OH/NH2 functionality, respectively. Increased fluid uptake capacity for the scaffolds treated with Ar+O-2 dielectric barrier discharge plasma (73.60%+/- 1.78) and dry air plasma jet (72.48%+/- 0.75) were also noted. Finally, initial cell attachment as well as seven-day cell viability, growth and proliferation performances were found to be significantly better for both plasma treated scaffolds than for untreated scaffolds.
  • Thumbnail Image
    Article
    Citation - WoS: 6
    Citation - Scopus: 7
    Hybrid Polymeric Scaffolds Prepared by Micro and Macro Approaches
    (Taylor & Francis As, 2017) Ozkan, Ozan; Sasmazel, Hilal Turkoglu; Turkoglu Sasmazel, Hilal
    Polymeric scaffolds with complex porous structures were fabricated with two different polymers by combining three fabrication methods in three steps, in which, nonwoven poly(e-caprolactone) microfibers were obtained with electrospinning and immersed in solvent cast chitosan solution poured in Petri dish to fabricate hybrid polymers, and finally the combined structure was freeze-dried with two different predrying techniques to obtain macropores in the structure. The resulting hybrid polymeric mats were found to have both microfibers and macroporosity due to the electrospinning as well as freeze-drying processes, which resemble the natural extracellular matrix. The optimized scaffolds that predried in the incubator at 40 degrees C for 5 h and then freeze-dried for 24 h exhibited contact angle value of 68.93 +/- 2.18 degrees with 3.252 +/- 0.783 MPa Young's modulus and 0.260 +/- 0.002 MPa yield strength as well as 1.35-fold cell yield in MRC5 fibroblast cell culture, compared to the commercial tissue culture polystyrene. [GRAPHICS] .