Dielectric barrier discharge and jet type plasma surface modifications of hybrid polymeric poly (ε-caprolactone)/chitosan scaffolds
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Date
2018
Authors
Özkan, Ozan
Sasmazel, Hilal Turkoglu
Şaşmazel, Hilal Türkoğlu
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Publisher
Sage Publications Ltd
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Abstract
In this study, dry air plasma jet and dielectric barrier discharge Ar+O-2 or Ar+N-2 plasma modifications and their effects on wettability, topography, functionality and biological efficiency of the hybrid polymeric poly (epsilon-caprolactone)/chitosan scaffolds were reported. The samples treated with Ar+O-2 dielectric barrier discharge plasma (80 sccm O-2 flow rate, 3-min treatment) or with dry air plasma jet (15-cm nozzle-sample distance, 13-min treatment) had the closest wettability (49.11 +/- 1.83 and 53.60 +/- 0.95, respectively) to the commercial tissue culture polystyrene used for cell cultivation. Scanning electron microscopy images and X-ray photoelectron spectrometry analysis showed increase in topographical roughness and OH/NH2 functionality, respectively. Increased fluid uptake capacity for the scaffolds treated with Ar+O-2 dielectric barrier discharge plasma (73.60%+/- 1.78) and dry air plasma jet (72.48%+/- 0.75) were also noted. Finally, initial cell attachment as well as seven-day cell viability, growth and proliferation performances were found to be significantly better for both plasma treated scaffolds than for untreated scaffolds.
Description
Turkoglu Sasmazel, Hilal/0000-0002-0254-4541; Ozkan, Ozan/0000-0002-9050-1583
Keywords
Dielectric barrier discharge, hybrid poly(epsilon-caprolactone), chitosan scaffolds, MRC5 fibroblast cells, plasma jet, plasma treatment
Turkish CoHE Thesis Center URL
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Citation
5
WoS Q
Q3
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Source
Volume
32
Issue
9
Start Page
1300
End Page
1313