Gültan, Tuğçe

Profile URL
https://hdl.handle.net/20.500.14411/8446
Name Variants
T., Gultan G.,Tuğçe T.,Gültan G.,Tugce G., Tugce Gültan, Tuğçe T.,Gultan Gültan,T. Tugce, Gultan Tuğçe, Gültan Gultan,T. Gultan, Tugce Gultan, T.
Job Title
Araştırma Görevlisi
Email Address
tugce.gultan@atilim.edu.tr
Main Affiliation
Chemical Engineering
Status
Former Staff
Website
ORCID ID
Scopus Author ID
Turkish CoHE Profile ID
Google Scholar ID
WoS Researcher ID
No research topics data found.

Sustainable Development Goals

NO POVERTY1
NO POVERTY
0
Research Products
ZERO HUNGER2
ZERO HUNGER
0
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GOOD HEALTH AND WELL-BEING3
GOOD HEALTH AND WELL-BEING
3
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QUALITY EDUCATION4
QUALITY EDUCATION
0
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GENDER EQUALITY5
GENDER EQUALITY
0
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CLEAN WATER AND SANITATION6
CLEAN WATER AND SANITATION
0
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AFFORDABLE AND CLEAN ENERGY7
AFFORDABLE AND CLEAN ENERGY
0
Research Products
DECENT WORK AND ECONOMIC GROWTH8
DECENT WORK AND ECONOMIC GROWTH
0
Research Products
INDUSTRY, INNOVATION AND INFRASTRUCTURE9
INDUSTRY, INNOVATION AND INFRASTRUCTURE
0
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REDUCED INEQUALITIES10
REDUCED INEQUALITIES
0
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SUSTAINABLE CITIES AND COMMUNITIES11
SUSTAINABLE CITIES AND COMMUNITIES
0
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RESPONSIBLE CONSUMPTION AND PRODUCTION12
RESPONSIBLE CONSUMPTION AND PRODUCTION
0
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CLIMATE ACTION13
CLIMATE ACTION
0
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LIFE BELOW WATER14
LIFE BELOW WATER
0
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LIFE ON LAND15
LIFE ON LAND
0
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PEACE, JUSTICE AND STRONG INSTITUTIONS16
PEACE, JUSTICE AND STRONG INSTITUTIONS
0
Research Products
PARTNERSHIPS FOR THE GOALS17
PARTNERSHIPS FOR THE GOALS
0
Research Products
This researcher does not have a Scopus ID.
This researcher does not have a WoS ID.
No records found in other affiliations.
Scholarly Output

3

Articles

3

Views / Downloads

2/0

Supervised MSc Theses

0

Supervised PhD Theses

0

WoS Citation Count

32

Scopus Citation Count

28

Patents

0

Projects

0

WoS Citations per Publication

10.67

Scopus Citations per Publication

9.33

Open Access Source

0

Supervised Theses

0

JournalCount
International Journal of Polymeric Materials and Polymeric Biomaterials2
Colloids and Surfaces A: Physicochemical and Engineering Aspects1
Current Page: 1 / 1

Scopus Quartile Distribution

Competency Cloud

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Filters

2019 - 201912020 - 20222

Settings

Author of Publication: search.filters.isAuthorOfPublication.3994c082-a388-436b-8eae-8fd3b23e20e6

Scholarly Output Search Results

Now showing 1 - 3 of 3
  • Article
    Citation - WoS: 14
    Citation - Scopus: 14
    Membrane Supported Poly(butylene Adipate-Co Nanofibrous Matrices as Cardiac Patch: Effect of Basement Membrane for the Fiber Deposition and Cellular Behavior
    (Elsevier, 2022-12) Gultan, Tugce; Gumusderelioglu, Menemse
    Electrospun nanofibrous matrices are convenient biomaterials that mimic extracellular matrices for adhesion, migration, proliferation, and differentiation of cells. The aim of this study is to optimize the electrospinning parameters for poly(butylene adipate-co-terephthalate) (PBAT) nanofiber production by the response surface methodology (RSM) and to develop a suitable material design for the usability of PBAT in cardiac tissue engineering. Therefore, electrospun PBAT nanofibrous matrices collected on solvent-casted polycaprolactone (PCL) or PBAT basement membranes at optimized conditions. The attachment and proliferation behavior of the H9C2 rat cardiomyoblasts investigated on different PBAT and PCL surface features as a model cell line. For this purpose, neat PBAT and PCL films have been used comparatively with both random (R-PBAT) and aligned PBAT (A-PBAT) nanofibers coated films. The effect of polymer concentration, flow rate, applied voltage, and needle tip -connector distance on fiber diameter and alignment was examined in the electrospinning process and optimum processing parameters were determined by RSM. The PBAT nanofibers were spun on basement membranes with 10% (w/v) polymer concentration, 1 mL/h volumetric flow rate, 2000 rpm collector rotation velocity (for aligned ones), 15 kV applied voltage, and 20 cm needle tip-collector distance. The average diameter of random (R-PBAT) and aligned (A-PBAT) nanofibers was calculated as 555 +/- 126 nm and 417 +/- 137 nm. The mechanical test results showed that the alignment topography increased the elastic modulus of PBAT nanofibers compared to random matrices. The alignment of fibers found as 91% and 75% within the +/- 10? range for A-PBAT/SC-PBAT and A-PBAT/SC-PCL, respectively. These findings showed that usage of PCL, instead of PBAT, as basement membrane decrease the alignment of deposited nanofibers. A 7-day cell culture study conducted with H9C2 cells seeded samples to investigate the influence of these differences on cell behavior. The results indicated that the alignment of fibers provides a suitable topography to proliferate and spread in myocyte morphology for H9C2 cells especially compared to neat films. Cellular behavior and nanofiber deposition have been affected by the usage of various basement membrane polymers. These findings demonstrated that the usage of basement membrane as support material provides the required thickness and mechanical properties to the aligned PBAT nanofiber matrices, and this double layer structure might be a promising candidate for cardiac tissue engineering with further studies
  • Article
    Citation - WoS: 10
    Citation - Scopus: 7
    Synergistic effect of fabrication and stabilization methods on physicochemical and biological properties of chitosan scaffolds
    (Taylor & Francis As, 2020-02-13) Gultan, Tugce; Bektas Tercan, Seyma; Cetin Altindal, Damla; Gumusderelioglu, Menemse
    In this study, the aim was to investigate the changes in the physical, chemical and biological properties of chitosan scaffolds obtained by freeze-drying and microwave-assisted gas foaming methods. Also, it was aimed to determine the most suitable one when scaffolds are subjected to different stabilization processes. To prevent the solubility of chitosan scaffolds, stabilization processes were carried out by treatment with ethanol (EtOH), sodium hydroxide (NaOH), or sodium bicarbonate (Na2CO3). The chemical and physical changes in the chitosan structure induced by different stabilization methods were investigated by characterization studies carried out comparatively with two-dimensional chitosan films. The results showed that, particularly, NaOH stabilization improved the physical, thermal, and mechanical properties of the bulk material. The wettability and surface roughness of the chitosan films were enhanced for cellular adhesion after stabilization. Cell culture studies revealed that variations in both fabrication and stabilization methods significantly affected in vitro cellular responses such as cell attachment, proliferation and viability. In conclusion, chitosan scaffolds fabricated by microwave-assisted gas foaming and stabilized by NaOH solution were found as the best structure due to their higher cellular activities.
  • Article
    Citation - WoS: 8
    Citation - Scopus: 7
    Enhancement of Scaffolding Properties for Poly(3-Hydroxybutyrate): Blending With Poly-Β and Wet Electrospinning
    (Taylor & Francis As, 2019-01-21) Catiker, E.; Konuk, E.; Gultan, T.; Gumusderelioglu, M.
    Poly-beta-alanine (PBA), and its derivatives poly(alpha-methyl-beta-alanine) and poly[N-(3-methoxypropyl-beta-alanine) were synthesized by hydrogen transfer polymerization (HTP). Porous 3 D matrices of poly(3-hydroxybutyrate) (P3HB) reinforced with PBA/its derivatives were obtained via lyophilization and wet electrospinning. However, mechanical properties of the porous matrices prepared by wet electrospinning were found to present superior performance for tissue engineering applications. Cell culture study was performed by using wet electrospun P3HB matrices doped with 10% (w/w) PBA which show better manipulation ability, chemical and mechanical properties. Scaffolds of P3HB-PBA (10% w/w) blend was determined to demonstrate better cell attachment and proliferation compared to the scaffolds of pure P3HB.