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Permanent URI for this collectionhttps://hdl.handle.net/20.500.14411/18
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Article Stochastic Comparisons of Mixtures of Heterogeneous Geometric Distributions Associated with Shock Models(Springer Heidelberg, 2026-05-14) Amini-Seresht, Ebrahim; Lorvand, Hamed; Balakrishnan, NarayanaswamyIn this paper, we discuss stochastic comparisons of two finite mixture models of different heterogeneous geometric distributions with different mixing proportions, in terms of usual stochastic, hazard rate, likelihood ratio and mean residual life orders. Finally, an application to shock models is discussed to illustrate the significance of the results established here.Article Optimizing Drone-Based Humanitarian Relief in Post-Disaster Scenarios: A Hybrid MCDM and Maximum Coverage Approach(Springer Heidelberg, 2026-05-02) Vural, DanismentThis study proposes a novel hybrid decision-making framework that integrates expert-driven supply prioritization via the Stepwise Weight Assessment Ratio Analysis (SWARA) method with an operationally constrained Maximum Coverage Problem (MCP) model to optimize drone-based humanitarian logistics in post-disaster scenarios. Grounded in a real-world case study of the 2023 Kahramanmaraş earthquake, the model systematically elicits expert preferences to rank critical supplies such as food, medical items, and cold chain products, and embeds these weights directly into a constrained MCP formulation. The model incorporates drone-specific operational limits, including battery consumption, payload capacity, and round-trip feasibility, to ensure realistic deployment strategies. Results show that scenario configurations with four to five strategically located drone bases, each equipped with four to five drones, can increase the achieved priority-weighted delivered quantity by up to 35-40% compared to minimal base-drone configurations within the proposed model framework. Moreover, the proposed framework improves responsiveness by prioritizing urgent deliveries and supporting more timely allocation decisions under operational constraints. Unlike traditional MCP approaches that rely on static weights, this method offers a context-sensitive and scalable optimization model informed by field expertise. The findings underscore the potential of structured expert-based weighting combined with operational optimization to enhance the efficiency and responsiveness of drone-assisted disaster relief systems.Article Defining the Danger Zone for Peroneal Nerve Safety in All-inside Lateral Meniscus Repair: An MRI-Based Study(Springer Heidelberg, 2026-05-05) Bilecenoglu, Burak; Yagmurkaya, Ummuhan; Esme, Simge; Demir, Berin Tugtag; Koksal, Ali; Demirel, MuratBackgroundThe peroneal (fibular) nerve (PN) traverses the posterolateral aspect of the knee joint, placing it at risk during lateral meniscus (LM) repair, given its proximity to the popliteus tendon (PoT).ObjectiveThis study aimed to evaluate the risk of PN injury and define a safe anchor penetration angle during all-inside LM repair.Materials and methodsA retrospective analysis was conducted using magnetic resonance imaging (MRI) scans of 327 individuals aged 18-60 years. The patellar tendon (PaT) and PoT widths were measured. The PN location relative to the PoT was determined. Distances from the PN to predefined medial and lateral reference lines across the PoT were calculated. The angular relationship between these lines and the transverse axis of the PaT was also analyzed for both anteromedial (AM) and anterolateral (AL) arthroscopic portals.ResultsThe PN-to-PoT distance was found to be comparable for both portals. However, the PN was significantly farther from the lateral reference line in the AM portal and from the medial reference line in the AL portal. The safe upper limit for anchor insertion was approximately 65 degrees from the AM portal and 88 degrees from the AL portal.ConclusionAppropriate portal selection and anchor angle during all-inside LM repair can significantly reduce the risk of PN injury. The AL portal offers a broader safe insertion range and may therefore improve nerve protection. HintergrundDer N. peroneus (PN, auch: N. fibularis) verl & auml;uft querüber die posterolaterale Seite des Kniegelenks, was ihn angesichts seiner N & auml;he zu Sehne des M. popliteus (& bdquo;popliteus tendon, PoT) bei einer Rekonstruktion des lateralen Meniskus(LM) einem Risiko aussetzt.ZielZiel der vorliegenden Studie war es, das Risiko einer PN-Verletzung zu ermitteln und einen sicheren Anker-Eindringwinkel bei der All-inside-LM-Rekonstruktion festzulegen.Material und MethodeDazu wurde eine retrospektive Auswertung unter Verwendung der Magnetresonanztomographie(MRT)-Ausnahmen von 327 Personen im Alter von 18-60 Jahren durchgeführt. Die Breite der Patellarsehne (& bdquo;patellar tendon, PaT) und der PoT wurden gemessen. Au ss erdem wurde die PN-Lokalisierung relativ zur PoT ermittelt. Die Abst & auml;nde vom PN zu vordefinierten medialen und lateralen Referenzlinien im Bereich der PoT wurde berechnet. Auch wurde die Winkelbeziehung zwischen diesen Linien und der Querachse der PaT sowohl für anteromediale (AM) als auch für anterolaterale (AL) arthroskopische Portale analysiert.ErgebnisseDer Abstand vom PN zur PoT wurde für beide Portale als vergleichbar bewertet. Jedoch war der PN von der lateralen Referenzlinie im AM-Portal und von der medialen Referenzlinie im AL-Portal signifikant weiter weg. Der sichere obere Grenzwert für die Ankerinsertion betrug ann & auml;hernd 65 degrees vom AM-Portal und 88 degrees vom AL-Portal.SchlussfolgerungEine geeignete Wahl des Portals und des Ankerwinkels bei der All-inside-LM-Rekonstruktion können das Risiko einer Verletzung des PN signifikant vermindern. Das AL-Portal bietet einen breiteren sicheren Einführbereich und kann daher zu einer besseren Nervenprotektion beitragen.Article A Note on Hazard Rates of Systems Protected by a Block(Springer Heidelberg, 2026-04-29) Eryilmaz, SerkanThis paper is concerned with the investigation of the properties of the hazard rate of the system protected by a block. By examining the characteristics of the hazard rate of the system supported by a protection block, a comparison is made with the redundancy method, according to the hazard rate. It is shown that the lifetime of the system supported by the protection block is larger than the lifetime of the system equipped with redundant system asymptotically in the hazard rate order. The extension of the results to a system with multiple components is also discussed for a consecutive k-out-of-n system.Article The Objects and Effects of the Restrictions by Object Under Art. 101(1) TFEU: Has the ECJ Solved the Riddle(Springer Heidelberg, 2026-03) Korkmaz Goka, EkinThe concept of by object infringements under Art. 101(1) of the TFEU has been a subject of ongoing controversy. Central to this debate are two primary issues: the interpretation of the term object and whether the effects or non-agreement elements in general should be considered when determining it. Should the latter question be answered affirmatively, further complications arise, particularly regarding the scope of the analysis in relation to the effects analysis and the allocation of the evidentiary burden between the parties. EU case law has significantly contributed to this debate, both in support and contradiction. The ECJ has, albeit implicitly, developed a system which seeks to strike a balance between competing interests while considering economic realities. However, the use of ambiguous terminology, inconsistencies in judicial rulings, and a lack of sufficiently clear explanations in certain cases have hindered the literature and national authorities from fully understanding the underlying system. This study aims to address this gap in the literature by providing a comprehensive legal analysis of the concept of by object infringements under Art. 101(1), in light of the framework established by the ECJ. The objective is to contribute to greater legal certainty in this area.Correction Rehabilitation in Neuromuscular Diseases: Best Turkish Practice Recommendations by Multidisciplinary Experts (Nov, 10.1007/S13760-025-02923-8, 2025)(Springer Heidelberg, 2026-01-28) Umay, Ebru; Tanigor, Goksel; Toraman, Fusun; Karaahmet, Ozgur; Bilgilisoy, Meral; Sertpoyraz, Filiz; Kasapoglu, BanuIn this article, a co-author name has been missed out in the original published version. The complete correct name is given below. Banu Kasapoğlu. The original article has been corrected. © The Author(s) under exclusive licence to Belgian Neurological Society 2026.Article Citation - WoS: 1Rehabilitation in Neuromuscular Diseases: Best Turkish Practice Recommendations by Multidisciplinary Experts(Springer Heidelberg, 2025-11-01) Umay, Ebru; Tanigor, Goksel; Toraman, Fusun; Karaahmet, Ozgur; Bilgilisoy, Meral; Sertpoyraz, Filiz; Nazli, Fatma; Kasapoglu, BanuBackground and aim:Neuromuscular diseases (NMDs) are a heterogeneous group of diseases including motor neurone diseases (MND), muscle diseases (MD), neuropathies and neuromuscular junction diseases (NMJD). NMDs are characterized by a wide range of symptoms and findings, depending on different underlying issues. Therefore, the literature includes specific management and/or rehabilitation recommendations for each subgroup and even for some diseases within these subgroups. Currently, neither in our country nor globally is there a comprehensive recommendation study that thoroughly addresses all aspects of NMD rehabilitation developed by experienced and specialized multidisciplinary experts in the field.Materials and methodsThe recommendations in this paper have been created by a multidisciplinary team for all patients without age limitation under the headings of peripheral neuropathy/polyneuropathy, MND, MD and NMJD using the seven-step and 3 round modified Delphi method via e-mail. The strength of agreements (SOA) was calculated for each item (recommendation) using percentages (response of between 8 and 10%), median values, and interquartile range with Kappa method.ResultsThe opinions of the experts were analysed according to the 3-round modified Delphi method, and a list of 110 items of recommendations for patients with NMDs of all ages was prepared in as much detail as possible to shed light on almost all questions and problems that may be encountered in clinical practice. There were 5 recommendations in the general management subsection, 20 recommendations in the rehabilitation indications subsection, 8 recommendations in the rehabilitation contraindications section, and 77 recommendations in the rehabilitation section (general principles 7 recommendations, modalities 13 recommendations, exercise characteristics 57 recommendations).ConclusionWe think that this study will be a light for physicians dealing with this patient group in clinical practice, as it includes fine details up to exercise prescriptions.Article A New Conservative Numerical Method for Strongly Coupled Nonlinear Schrödinger Equations(Springer Heidelberg, 2025-09-30) Ors, Ridvan Fatih; Koroglu, Canan; Aydin, AyhanIn this paper, a numerical method based on the conservative finite difference scheme is constructed to numerically solve the strongly coupled nonlinear Schr & ouml;dinger (SCNLS) equation. Conservative properties such as energy and mass of the SCNLS equation have been proven. In particular a fourth-order central difference scheme is used to discretize the the spatial derivative and a second-order Crank-Nicolson type discretization is used to discretize the temporal derivative. It has been shown that the proposed scheme preserves the discrete mass and energy. The existence of discrete solution is also investigated. Several numerical results are given to demonstrate the preservation properties of the new method. Also, the effect of the linear coupling parameters on the evolution of solitary waves is investigated.Article Factors Influencing the Transition Time From Psoriasis to Psoriatic Arthritis: A Real-World Multicenter Analysis(Springer Heidelberg, 2025-09-09) Kilic, Gamze; Kilic, Erkan; Tekeoglu, Ibrahim; Sargin, Betul; Cengiz, Gizem; Balta, Nihan Cuzdan; Nas, KemalTo identify clinical and demographic predictors associated with the timing of transition from psoriasis (PsO) to psoriatic arthritis (PsA), and to compare the characteristics of patients with concurrent PsO-PsA onset versus those with prolonged transition. A multi-center, observational study was conducted using data from the Turkish League Against Rheumatism (TLAR) network including PsA patients fulfilling CASPAR criteria. Patients were categorized into two groups: Group 1 (concurrent PsO and PsA onset within +/- 1 year) and Group 2 (prolonged transition to PsA, > 1 year after PsO). Demographic, clinical, and laboratory characteristics, disease activity, and patient-reported outcomes were compared between groups. Logistic regression was employed to determine independent predictors of prolonged transition. Among 799 patients (mean age 46.8 +/- 12.3 years), 237 (29.7%) had concurrent onset and 562 (70.3%) had a prolonged transition, with a mean PsO-to-PsA interval of 12.9 +/- 9.6 years. Depression (p = 0.005) and fatigue levels (p = 0.011) were significantly higher in patients with prolonged transition to PsA. Multivariate analysis revealed that scalp psoriasis (OR = 7.162), nail psoriasis (OR = 3.270), family history of PsO (OR = 1.813), and enthesitis ever (OR = 2.187) were associated with prolonged transition. Conversely, family history of PsA (OR = 0.421) and older age at PsO onset (OR = 0.957) predicted shorter transition. Prolonged transition from PsO to PsA is influenced by distinct clinical and demographic factors. Scalp/nail psoriasis, family history of PsO, and enthesitis ever may signal higher risk for prolonged PsA onset. Recognizing these markers can support timely referral and intervention, minimizing diagnostic delay and improving long-term patient outcomes.Article Citation - Scopus: 1Patient Safety in Healthcare: A Proposal for Ensuring the Use of Regulation-Compliant Safety Devices(Springer Heidelberg, 2025-08-21) Bayrak, TuncayMedical devices used in health care should fulfill the requirements of the technical regulations to protect patient health. Difficulties in enforcing stricter rules in the new medical device regulations may negatively affect the continuity of care. This study examines the status of manufacturers' compliance with medical device regulations, based on predefined criteria, and proposes a collaborative action plan and an approach to verify regulatory compliance. We conducted a nationwide survey comprising questions grouped by criteria to understand the status of the manufacturers in terms of compliance with the Medical Device Regulation. Four hundred sixty-seven manufacturers participated in the survey. We achieved a Cronbach's alpha of 0.77, which indicates that the survey is statistically reliable. We applied the independent samples t-test to the responses to determine significant features per question and employed factor analysis to investigate the relationships of the questions. The results of independent samples t-tests showed statistically significant differences across groups in replies to several survey items (p < 0.05), indicating that participants' opinions varied based on their demographic characteristics. We applied Exploratory Factor Analysis to introduce the relationships between the questions. The analysis revealed that manufacturers continue to face substantial challenges in acquiring sufficient knowledge and operational capability to meet MDR requirements. In light of these findings, we focused on the person responsible for regulatory compliance, who plays a central role in maintaining regulatory compliance within manufacturing organizations. We proposed an action plan at the macro level to introduce more effective action plans in cooperation with other stakeholders, including healthcare providers, and a verification approach for regulatory compliance to enhance the Person Responsible for Regulatory Compliance's competence. Manufacturers should implement effective postmarketing clinical follow-up plans involving device-oriented parameters for monitoring in the healthcare system, especially in collaboration with health professionals.