Profile URL: https://hdl.handle.net/20.500.14411/7790
Job Title:Araştırma Görevlisi
Email Address:beyza.karaduz@atilim.edu.tr
Main Affiliation:Atılım University
Status: Former Staff
Name Variants:
Beyza Nur, Karadüz B.,Karadüz
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Article Citation - WoS: 23Citation - Scopus: 23Validity and Reliability of 6-Minute Pegboard and Ring Test in Patients With Asthma(Taylor & Francis Ltd, 2021-05-31) Calik-Kutukcu, Ebru; Tekerlek, Haluk; Bozdemir-Ozel, Cemile; Karaduz, Beyza Nur; Cakmak, Aslihan; Inal-Ince, Deniz; Karakaya, GulObjective The 6-minute pegboard and ring test (6PBRT) is a test of upper-extremity functional capacity designed for and validated in chronic obstructive pulmonary disease. The aim of this study was to evaluate the validity and reliability of the 6PBRT in asthma patients. Methods Thirty-four adults (30 women, 4 men) with well-controlled asthma were included. Unsupported upper-extremity exercise capacity was assessed using 6PBRT, maximal arm exercise capacity using an arm ergometer, handgrip strength using a hand dynamometer, activities of daily living with the London Chest Activities of Daily Living Scale (LCADL), Milliken ADL scale (MAS) and health-related quality of life using the Asthma Quality of Life Questionnaire (AQLQ) and Health Assessment Questionnaire Disability Index (HAQ-DI). Results The 6PBRT showed moderate to excellent test-retest reliability with an intraclass correlation coefficient (ICC) value of 0.872 [95% confidence interval (CI) 0.702-0.941]. The 6PBRT was reproducible according to Bland-Altman analysis, with upper and lower limits of agreement of 53.51 and -25.08 rings moved, respectively. The 6PBRT score was significantly correlated with maximum workload (r = 0.514, p = 0.002) achieved in the arm ergometer test, change in dyspnea during 6PBRT (r = -0.402, p = 0.020), LCADL-self-care (r = -0.364, p = 0.037), MAS total (r = 0.483, p = 0.005), AQLQ-symptom domain (r = 0.420, p = 0.026) and HAQ-DI total scores (r = -0.390, p = 0.025). Conclusions The 6PBRT can be used as a valid and reliable test to evaluate functional arm exercise capacity in patients with well-controlled asthma.Article Determinants of Peak Oxygen Pulse in Disorders of Glucose Metabolism(2022) Dağdelen, Selçuk; Kutukcu, E Calik; Arıkan, Hülya; Karadüz, Beyza Nur; Bozdemir-özel, CemileAbstract Funding Acknowledgements Type of funding sources: None. Background/Introduction Oxygen pulse reflects oxygen consumption per heart beat and it provides an information for stroke volume and peripheral oxygen extraction during exercise. Further this, oxygen pulse reported as prognostic for all-cause and cardiovascular mortality. Disorders of glucose metabolism (i.e., prediabetes and overt diabetes mellitus) are important risk factor for cardiovascular disease and might disrupt oxygenation. Purpose We aimed to investigate determinants of peak oxygen pulse in patients with prediabetes and overt diabetes mellitus. Methods Twenty-six patients with disorders of glucose metabolism (mean age: 48,62±7,08 years, HbA1c: 6,51±0,94) were included in the study. Laboratory parameters which very low density lipoprotein cholesterol (VLDL), low and high density lipoprotein (HDL, LDL) levels, HbA1c and C-reactive protein (CRP) levels of participiants were recorded. Patient performed a symptom limited maximal cardiopulmonary test (CPET). Results There was statistically significant negative correlation between oxygen pulse with VLDL (r=-512, p=0,018), CRP (r=-665, p<0.001), waist circumference (r=-471, p=0,015). Based on linear regression analysis, we found that CRP and VLDL explained %40 of variance Oxygen pulse. (R=0.637, R2=0.406, F(2-26). 6.160, p=0.009, constant=0.133). Conclusion(s) CRP and very low density lipoprotein cholesterol levels is independent predictors of oxygen pulse. Management of VLDL levels and inflammation can improve peripheral oxygenization in prediabetes and overt diabetes mellitus.Conference Object The Validity and Reliability of the 6 Minute Pegboard and Ring Test in Patients With Controlled and Partially Controlled Asthma(European Respiratory Soc Journals Ltd, 2020-09-07) Kutukcu, Ebru Calik; Karaduz, Beyza Nur; Cakmak, Aslihan; Inal-Ince, Deniz; Vardar-Yagli, Naciye; Saglam, Melda; Karakaya, Gul[No Abstract Available]Article Tip 2 Diyabetli Bireylerde Kardiyovasküler Hastalıklar Risk Faktörleri Bilgi Düzeyi ve Fiziksel Aktivite Seviyelerinin İncelenmesi(2021) Özel, Cemile Bozdemir; Arıkan, Hülya; Dağdelen, Selçuk; Kütükçü, Ebru Çalık; Karadüz, Beyza Nur; Kabakçı, Mevlana Giray; İnce, Deniz İnal; Karadüz-durukan, Beyza Nur; Inal-ınce, DenizAmaç: Tip 2 diyabetli bireylerde fiziksel aktivite kardiyovasküler hastalıklar risk faktörleri açısından önemlidir. Çalışmanın amacı, Tip 2 diyabetli bireylerde kardiyovasküler hastalıklar risk faktörleri bilgi düzeyi ve fiziksel aktivite seviyelerini değerlendirmekti.Yöntem: Çalışmaya 47 tip 2 diyabetli birey (yaş ortalaması: 50,80±5,61 yıl) dahil edildi. Vücut yağı biyoelektrik empedans analizi ile değerlendirildi. Kardiyovasküler hastalıklar risk faktörleri bilgi düzeyi, Kardiyovasküler Hastalıklar Risk Faktörleri Bilgi Düzeyi Ölçeği (0-28) ile değerlendirildi. Koroner arter hastalık risk faktörleri hesaplandı. Fiziksel aktivite seviyeleri yedi gün boyunca üç eksenli akselerometre ile ölçüldü.Bulgular: Kardiyovasküler hastalıklar risk faktörleri bilgi düzeyi ölçeği 20,69±3,86 puandı. Framingham risk skoru 8,85±3,06 olarak kaydedildi. Günlük ortalama adım sayısı 7195±3441,20 adım/gün olarak hesaplandı. Metabolik eşdeğer ile açlık kan glukozu (r=-0.381; p=0,018), vücut kütle indeksi (r=-0,665; p<0,001), bel çevresi (r=-0,381; p=0,018), vücut yağ yüzdesi (r=-0,554; p=0,002) ile ilişkiliydi. Kardiyovasküler hastalıklar bilgi düzeyi ortalamanın üzerinde bulundu. Sonuç: Tip 2 diyabetli bireylerde kardiyovasküler hastalıklar bilgi düzeyi ortalamanın üzerinde olmasına rağmen, bireylerin adım sayıları düşüktü. Tip 2 diyabetli bireyleri fiziksel aktivite konusunda bilinçlendirmeye ve adım sayısının yanı sıra aktivite şiddetine de odaklanarak fiziksel aktiviteyi arttırmaya yönelik uygulamalar amaçlanmalıdır.Article Citation - WoS: 3Citation - Scopus: 5Subclinical Inflammation Is Associated With Reductions in Muscle Oxygenation, Exercise Capacity and Quality of Life in Adults With Type 2 Diabetes(Elsevier, 2020-07) Bozdemir-Ozel, Cemile; Arikan, Hulya; Calik-Kutukcu, Ebru; Karaduz, Beyza Nur; Inal-Ince, Deniz; Kabakci, Giray; Dagdelen, SelcukObjectives: Exercise capacity is related to both morbidity and mortality in patients with type 2 diabetes (T2DM). The aim of this study was to investigate the relationship between subclinical inflammation level, exercise capacity, muscle oxygenation and quality of life in T2DM. Methods: This study includes 28 patients with T2DM (mean age, 51.5 +/- 5.0 years; male-to-female ratio, 6:22). Exercise capacity was evaluated using an incremental symptom-limited maximal exercise test on a bicycle ergometer. Muscle oxygenation was investigated using a wearable lactate-measuring device. Diabetes-specific quality of life was assessed using the Diabetes Quality of Life Questionnaire (DQOL). Subclinical inflammation was assessed using C-reactive protein (CRP) levels. Results: CRPlevelwasnegatively correlatedwith peakworkload during the test (r=-0.588, p=0.002), muscle oxygenation (r=-0.465, p= 0.019) and the psychological impact of treatment subscale of the DQOL (r= e0.540, p=0.017), and positively correlated with body mass index (r=0.519, p=0.008), waist circumference (r=0.426, p=0.038) and fat percentage (r=0.573, p=0.004). Therewasnocorrelation betweenCRPand fasting blood glucose or glycated hemoglobin level (p>0.05). Peakworkloadwas inversely related to fat percentage (r=-0.467, p=0.016) and the DQOLworry about the future impact of diabetes subscale (r=-0.501, p=0.021). Conclusions: In our study, subclinical inflammation negatively affected muscle oxygenation, exercise capacity and quality of life independently of glycemic indicators. Our findings suggest that the degree of glycemic control is insufficient to explain lower exercise capacity. Further studies are needed to investigate subclinical inflammation-reducing interventions in T2DM. (C) 2020 Canadian Diabetes Association.Article Investigation of Cardiovascular Disease Risk Factors Knowledge and Physical Activity Levels in Patients with Type 2 Diabetes(2019) İnce, Deni̇z İnal; Arıkan, Hülya; Karadüz, Beyza Nur; Bozdemir-özel, Cemile; Kabakçı, Giray; Dağdelen, Selçuk; Çalık-kütükçü, EbruArticle Citation - WoS: 3Citation - Scopus: 3Energy Expenditure and Glucose-Lowering Effect of Different Exercise Modalities in Diabetes Mellitus(Elsevier Sci Ltd, 2022-12) Bozdemir-Ozel, Cemile; Arikan, Hulya; Calik-Kutukcu, Ebru; Karaduz, Beyza Nur; Inal-Ince, Deniz; Kabakci, Giray; Dagdelen, SelcukObjectives Hypoglycaemia is a serious complication of exercise in patients with type 2 diabetes mellitus (T2DM). The aim of this study was to test energy expenditure and the degree of the glucose-lowering effect of different exercise modalities. Design Cross-sectional study Participants This study included 44 patients {35 women and nine men, mean age 51 [standard deviation (SD) 5] years} with T2DM [mean HbA1c 7% (SD 1%)]. Main outcome measures Standardised exercise tests for walking, running and cycling were performed using the 6-minute walk test (6MWT), incremental shuttle walk test (ISWT), and symptom-limited maximal cycle exercise test, respectively. Energy expenditure was assessed with a multisensory accelerometer. Change in capillary glucose levels ( increment glucose) was measured before and after each exercise modality. Results increment Glucose was lower in the 6MWT {median 14 [interquartile range (IQR) 22] mg/dl} than in the ISWT [median 18 (IQR 23) mg/ dl; median difference 7 mg/dl, 95% confidence interval (CI) of the difference 3-11] and the cycle test [median 18 (IQR 24) mg/dl; median difference 7 mg/dl, 95% CI 0-16]. Energy expenditure was lower during the 6MWT [median 41 (IQR 18) Kcal] compared with the ISWT [median 51 (IQR 23) Kcal; median difference 11 Kcal, 95% CI 6-16] and the cycle test [median 44 (IQR 25) Kcal; median difference 6 Kcal, 95% CI 0-13]. Conclusions Energy expenditure and corresponding glucose-lowering effect during exercise in patients with T2DM can be predicted from the results of an exercise test. The type of exercise is related to the risk of hypoglycaemia. Walking is associated with the lowest energy expenditure and risk of hypoglycaemia, while cycling and running/jogging cause higher energy expenditure and greater reductions in glucose in patients with T2DM. Contribution of the paper center dot Energy expenditure and risk of hypoglycaemia during exercise can be predicted by exercise tests. center dot The intensity and type of exercise are related to the risk of hypoglycaemia. center dot The change in glucose level was greater for running and cycling than for walking. (c) 2022 Chartered Society of Physiotherapy. Published by Elsevier Ltd. All rights reserved.Conference Object The Association Between Bodex Index and Activities of Daily Living, Occupational Performance, Psychosocial Status and Health Related Quality of Life in Patients With Copd(European Respiratory Soc Journals Ltd, 2020-09-07) Karaduz, Beyza Nur; Calik-Kutukcu, Ebru; Oksuz, Cigdem; Saglam, Melda; Inal-Ince, Deniz; Vardar-Yagli, Naciye; Coplu, Lutfi[No Abstract Available]Conference Object Citation - WoS: 1Responses To Two Different High-Intensity Interval Exercise Training Protocols on Pulmonary Function and Respiratory Muscle Strength in Diabetes Mellitus(European Respiratory Soc Journals Ltd, 2021-09-05) Ozel, Cemile Bozdemir; Arikan, Hulya; Kutukcu, Ebru Calik; Karaduz, Beyza Nur; Ince, Deniz Inal; Kabakci, Giray; Dagdelen, Selcuk[No Abstract Available]Conference Object A Comparison of Arm Exercise Capacity and Activities of Daily Living Between Well-Controlled Asthma Patients With and Without Severe Fatigue During Daily Life(European Respiratory Soc Journals Ltd, 2021-09-05) Karaduz, Beyza Nur; Calik-Kutukcu, Ebru; Cakmak, Aslihan; Ince, Deniz Inal; Vardar-Yagli, Naciye; Saglam, Melda; Karakaya, Gul[No Abstract Available]